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actavis patient assistance transdermal clonidine

by Nettie Hane V Published 2 years ago Updated 1 year ago
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Are there any patient assistance programs for clonidine?

Patient Assistance Programs for Clonidine. Patient assistance programs (PAPs) are usually sponsored by pharmaceutical companies and provide free or discounted medicines to low income or uninsured and under-insured people who meet specific guidelines.

What is the clonidine transdermal system?

Clonidine Transdermal System, USP is a transdermal system providing continuous systemic delivery of clonidine for 7 days at an approximately constant rate. Clonidine is a centrally acting alpha-agonist hypotensive agent.

What is the steady state of clonidine in the human body?

Steady-state clonidine plasma levels are obtained within 3 days after transdermal application to the upper outer arm and increase linearly with increasing size of the transdermal patch. Mean steady-state plasma concentrations with the 4.1 cm 2 , 8.2 cm 2 and 12.3 cm 2 systems are approximately 0.4 ng/mL, 0.8 ng/mL, and 1.1 ng/mL, respectively.

What is the mechanism of action of clonidine?

Clonidine stimulates alpha-adrenoreceptors in the brain stem. This action results in reduced sympathetic outflow from the central nervous system and in decreases in peripheral resistance, renal vascular resistance, heart rate, and blood pressure. Renal blood flow and glomerular filtration rate remain essentially unchanged.

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How much does clonidine cost?

Clonidine Prices. The cost for clonidine oral tablet 0.1 mg is around $10 for a supply of 8 tablets, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.

What is clonidine used for?

Clonidine is a member of the antiadrenergic agents, centrally acting drug class and is commonly used for ADHD, Alcohol Withdrawal, Anxiety, and others.

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

Uses

Clonidine relaxes and expands (dilates) blood vessels resulting in lowered blood pressure. It is used to treat high blood pressure (hypertension).

Uses

This medication may also be used to ease withdrawal symptoms associated with the long-term use of narcotics, alcohol, and nicotine (smoking). Other possible uses are to treat Tourette's syndrome, prevent specific headaches (e.g., migraines, cluster), or hot flashes associated with menopause.

How To Use

Apply clonidine patches to a hairless area of the skin on the upper arm or chest every 7 days. Apply each patch to a different area than the previous one to avoid skin irritation. Apply a new patch before removing the old one. Be sure to remove the hard plastic backing on the patch before using. Do not apply patch to broken or irritated skin.

Side Effects

Dizziness, drowsiness, headache, constipation, loss of appetite, fatigue, nasal congestion and dry eyes may occur during first several days as your body adjusts to the medication. To avoid dizziness and lightheadedness when rising from a seated or lying position, get up slowly.

Precautions

Tell your doctor your medical history, especially of: heart problems, blood vessel problems, kidney problems, depression, Raynaud's syndrome, allergies (especially drug allergies). Before having surgery, including dental surgery, tell the doctor you use clonidine. Clonidine should be used only when clearly needed during pregnancy.

Drug Interactions

Tell your doctor of all prescription and nonprescription drugs you use, especially of: beta-blockers (e.g., atenolol, propranolol), tricyclic antidepressants (e.g., amitriptyline, doxepin). Do not start or stop any medicine without doctor or pharmacist approval.

How to apply clonidine patch?

2) Select a hairless area such as on the upper, outer arm or upper chest.

How long does it take for clonidine to reach plasma levels?

Therapeutic plasma clonidine levels are achieved 2 to 3 days after initial application of clonidine transdermal system.

How long does it take for clonidine to show signs of overdose?

Signs and symptoms of overdose generally occur within 30 minutes to two hours after exposure. As little as 0.1 mg of clonidine has produced signs of toxicity in children. If symptoms of poisoning occur following dermal exposure, remove all clonidine transdermal systems.

How long does it take to stop clonidine?

When discontinuing therapy with clonidine transdermal system, the physician should reduce the dose gradually over 2 to 4 days to avoid withdrawal symptomatology.

How long does clonidine stay in your system?

If the clonidine transdermal system is removed and not replaced with a new system, therapeutic plasma clonidine levels will persist for about 8 hours and then decline slowly over several days. Over this time period, blood pressure returns gradually to pretreatment levels. Close. CLINICAL PHARMACOLOGY.

What are the factors that determine the labeling of clonidine?

Decisions to include these reactions in labeling are typically based on one or more of the following factors: (1) seriousness of the reaction, (2) frequency of reporting, or (3) strength of causal connection to clonidine transdermal system. Body as a Whole: Fever; malaise; weakness; pallor; and withdrawal syndrome.

Can you remove clonidine from a MRI?

Because the clonidine transdermal system patch contains aluminum, it is recommended to remove the system before undergoing an MRI. Information for Patients.

Program Details

PatientAssistance.com is glad to present this offer finding to you. You will find the program details located through the offer link below.

How To Use

Simply print this page and bring to your local pharmacy. If you have any issues please have the pharmacist call 1-800-577-6484.

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Clinical Pharmacology

  • Clonidine stimulates alpha-adrenoreceptors in the brain stem. This action results in reduced sympathetic outflow from the central nervous system and in decreases in peripheral resistance, renal vascular resistance, heart rate, and blood pressure. Renal blood flow and glomerular filtrati…
See more on medlibrary.org

Indications and Usage

  • Clonidine transdermal system is indicated in the treatment of hypertension. It may be employed alone or concomitantly with other antihypertensive agents.
See more on medlibrary.org

Contraindications

  • Clonidine transdermal system should not be used in patients with known hypersensitivity to clonidine or to any other component of the system.
See more on medlibrary.org

Warnings

  • Withdrawal Patients should be instructed not to discontinue therapy without consulting their physician. Sudden cessation of clonidine treatment has, in some cases, resulted in symptoms such as nervousness, agitation, headache, tremor, and confusion accompanied or followed by a rapid rise in blood pressure and elevated catecholamine concentrations in the plasma. The likeli…
See more on medlibrary.org

Important Note

  • The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug. CLONIDINE - TRANSDERMAL (KLAHN-eh-deen) …
See more on patientassistance.com

Uses

  • Clonidine relaxes and expands (dilates) blood vessels resulting in lowered blood pressure. It is used to treat high blood pressure (hypertension). OTHER
See more on patientassistance.com

How to Use

  • Apply clonidine patches to a hairless area of the skin on the upper arm or chest every 7 days. Apply each patch to a different area than the previous one to avoid skin irritation. Apply a new patch before removing the old one. Be sure to remove the hard plastic backing on the patch before using. Do not apply patch to broken or irritated skin. If th...
See more on patientassistance.com

Side Effects

  • Dizziness, drowsiness, headache, constipation, loss of appetite, fatigue, nasal congestion and dry eyes may occur during first several days as your body adjusts to the medication. To avoid dizziness and lightheadedness when rising from a seated or lying position, get up slowly. Also limit your intake of alcoholic beverages and avoid overheating which will aggravate these effect…
See more on patientassistance.com

Precautions

  • Tell your doctor your medical history, especially of: heart problems, blood vessel problems, kidney problems, depression, Raynaud's syndrome, allergies (especially drug allergies). Before having surgery, including dental surgery, tell the doctor you use clonidine. Clonidine should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Clonidin…
See more on patientassistance.com

Drug Interactions

  • Tell your doctor of all prescription and nonprescription drugs you use, especially of: beta-blockers (e.g., atenolol, propranolol), tricyclic antidepressants (e.g., amitriptyline, doxepin). Do not start or stop any medicine without doctor or pharmacist approval.
See more on patientassistance.com

Overdose

  • If overdose is suspected, remove the patch. Contact your local poison control center or emergency room immediately. Symptoms of overdose may include lightheadedness, weakness, sleepiness, irritability, constricted pupils, vomiting, slow heart rate, and slowed breathing.
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Notes

  • It is important to have your blood pressure checked regularly while taking this medication. Learn how to monitor your blood pressure. Discuss this with your doctor. Do not allow anyone else to take this medication.
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Missed Dose

  • If you miss a dose, use it as soon as remembered; do not use if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.
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