How much does it cost to pay for Actemra?
†The final amount owed by patients may be as little as $5, but may vary depending on the patient's health insurance plan. Eligible commercially insured patients who are prescribed ACTEMRA for an FDA-approved use can receive up to $15,000 in assistance annually for drug costs.
What is the Actemra co-pay card program?
If eligible commercially insured patients need assistance with their out-of-pocket costs, ACTEMRA Access Solutions can refer them to the ACTEMRA Co-pay Card Program.* *Eligibility criteria apply. Not valid for patients using federal or state government programs to pay for their medications and or administration of their Genentech medication.
What is Actemra used to treat?
Important Safety Information & Indication. ACTEMRA is indicated for the treatment of adult patients with moderately to severely active rheumatoid arthritis (RA) who have had an inadequate response to one or more Disease-Modifying Anti-Rheumatic Drugs (DMARDs).
What are the contraindications for Actemra?
ACTEMRA is contraindicated in patients with known hypersensitivity to ACTEMRA. Other serious or potentially life-threatening adverse reactions that have been reported in clinical trials with ACTEMRA include gastrointestinal perforations. Use ACTEMRA with caution in patients who may be at risk for GI perforations.
How long does it take to get an actrema injection?
Can ACTEMRA cause tears in the stomach?
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ACTEMRA Instructions for Use - Genentech
• Take the box containing the syringe out of the refrigerator and open the box. Do not touch the trigger fingers on the syringe as this may damage the syringe. • Remove 1 single-use ACTEMRA prefilled syringe from the box and let it warm up for 30 minutes to allow it to
Actemra: Uses, Dosage & Side Effects - Drugs.com
Warnings. Actemra affects your immune system. You may get infections more easily, even serious or fatal infections. Call your doctor if you have a fever, chills, aches, tiredness, cough, skin sores, diarrhea, weight loss, or burning when you urinate.. Actemra may also cause a perforation (a hole or tear) in your stomach or intestines.
Subcutaneous Injections for RA | ACTEMRA® (tocilizumab)
Review Important Side Effect Information & training. Before you start taking ACTEMRA injections, your doctor or nurse should review the ACTEMRA Medication Guide, including Instructions for Use, with you.Reviewing the Medication Guide should help you to better understand the risks and benefits of your RA treatment.
ACTEMRA SC formulation is not intended for intravenous administration.
4 . 1 INDICATIONS AND USAGE . 1.1 Rheumatoid Arthritis (RA) ACTEMRA ® (tocilizumab) is indicated for the treatment of adult patients with moderately to severely active
Who should not take ACTEMRA?
Do not take ACTEMRA if you are allergic to tocilizumab, or any of the ingredients in ACTEMRA.
How long after ACTEMRA can you check cholesterol?
Increase in blood cholesterol levels: your cholesterol levels should be checked 4 to 8 weeks after you start receiving ACTEMRA.
How to report side effects of Genentech?
Tell your healthcare provider if you have any side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects to Genentech at 1-888-835-2555.
Can you take actherma with diverticulitis?
If you have diverticulitis (inflammation in parts of the large intestine), talk to your healthcare provider before taking ACTEMRA. Some people taking ACTEMRA may develop a hole in the wall of their stomach or intestines (also known as a perforation). This happens most often in people who also take nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, or methotrexate.
Can you die from actherma?
Serious allergic reactions, including death, can happen with ACTEMRA. These reactions can happen with any infusion or injection of ACTEMRA, even if they did not occur with an earlier infusion or injection. Tell your healthcare provider before your next dose if you had hives, rash or flushing after your injection.
Can you get multiple sclerosis from actrea?
While rare, Multiple Sclerosis has been diagnosed in people who take ACTEM RA. It is not known what effect ACTEMRA may have on some nervous system disorders.
Does actuma increase cancer risk?
ACTEMRA may increase your risk of certain cancers by changing the way your immune system works .
What is Genentech Patient Foundation?
The Genentech Patient Foundation gives free Genentech medicine to people who don't have insurance or who have financial concerns and meet eligibility criteria. Two forms are needed to enroll in the Genentech Patient Foundation:
Is Actemra a RSVP?
ACTEMRA ® (tocilizumab) patients enrolled in ACTEMRA Access Solutions are automatically enrolled in RSVP. Use this form to opt out of this program.
What is ACTEMRA used for?
ACTEMRA is indicated for the treatment of adult patients with moderately to severely active rheumatoid arthritis (RA) who have had an inadequate response to one or more Disease-Modifying Anti-Rheumatic Drugs (DMARDs). ACTEMRA is indicated for the treatment of giant cell arteritis (GCA) in adult patients.
Where to report side effects of Actemra?
You may report side effects to the FDA at (800) FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at (888) 835-2555.
How many ISRs are there in ACTEMRA SC?
During the 1-year study, a frequency of 28.8% (15/52) ISRs was observed in ACTEMRA-SC treated PJIA patients. These ISRs occurred in a greater proportion of patients at or above 30 kg (44.0%) compared with patients below 30 kg (14.8%). All ISRs were mild in severity and none of the ISRs required patient withdrawal from treatment or dose interruption.
What are the most common adverse reactions to methotrexate?
The most common serious adverse reactions were serious infections. The most common serious infections included pneumonia, urinary tract infection, cellulitis, herpes zoster, gastroenteritis, diverticulitis, sepsis and bacterial arthritis. In the ACTEMRA-IV monotherapy clinical study, the rate of serious infections was 3.6 per 100 patient-years in the ACTEMRA group and 1.5 per 100 patient-years in the methotrexate group. The rate of serious infections in the 4 mg/kg and 8 mg/kg ACTEMRA plus DMARD groups was 4.4 and 5.3 events per 100 patient-years, respectively, compared to 3.9 events per 100 patient-years in the placebo plus DMARD group.
How long does it take for ACTEMRA to show signs of liver damage?
Some of these cases have resulted in liver transplant or death. Time to onset for cases ranged from months to years after treatment initiation. Most cases presented with marked elevations of transaminases (> 5 times ULN), and some cases presented with signs or symptoms of liver dysfunction and only mildly elevated transaminases.
What are the most common adverse events in ACTEMRA IV?
The most common adverse events (at least 5%) seen in ACTEMRA-IV treated patients in the 12-week controlled portion of the study were: upper respiratory tract infections, headache, nasopharyngitis, and diarrhea.
What is the rate of infection in actrea IV?
The rate of infections in the ACTEMRA-IV all-exposure population was 163.7 per 100 patient-years. The most common events observed were nasopharyngitis and upper respiratory tract infections. The rate of serious infections was numerically higher in patients weighing less than 30 kg treated with 10 mg/kg ACTEMRA-IV (12.2 per 100 patient-years) compared to patients weighing at or above 30 kg, treated with 8 mg/kg ACTEMRA-IV (4.0 per 100 patient-years). The incidence of infections leading to dose interruptions was also numerically higher in patients weighing less than 30 kg treated with 10 mg/kg ACTEMRA-IV (21%) compared to patients weighing at or above 30 kg, treated with 8 mg/kg ACTEMRA-IV (8%).
What should I tell my healthcare provider before receiving ACTEMRA?
ACTEMRA may not be right for you. Before receiving ACTEMRA, tell your healthcare provider if you:
What are the side effects of ACTEMRA?
These blood tests are to check for the following side effects of ACTEMRA: Low neutrophil count: neutrophils are white blood cells that help the body fight infection. Low platelet count: platelets are blood cells that help with clotting, which stops bleeding. Increase in liver function test levels.
How long after ACTEMRA can you check cholesterol?
Increase in blood cholesterol levels: your cholesterol levels should be checked 4 to 8 weeks after you start receiving ACTEMRA.
How to report side effects of Genentech?
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects to Genentech at 1-888-835-2555. Please see full Prescribing Information and the Medication Guide, including Serious Side Effects, for more Important Safety Information.
What to do if you don't have insurance for Genentech?
If you do not have insurance, or if your insurance does not cover your Genentech medicine, you must meet a different set of income requirements. To find out if you are eligible for any of our programs, please use the tool below or call 1-800-ACTEMRA (1-800-228-3672) to talk with a specialist.
Can you take actherma with diverticulitis?
If you have diverticulitis (inflammation in parts of the large intestine), talk to your healthcare provider before taking ACTEMRA. Some people taking ACTEMRA may develop a hole in the wall of their stomach or intestines (also known as a perforation). This happens most often in people who also take nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, or methotrexate.
Should you test for TB before taking ACTEMRA?
Your healthcare provider should test you for TB before starting and during treatment with ACTEMRA. Before starting ACTEMRA, tell your healthcare provider if you have: an infection, think you may have an infection, are being treated for an infection, or get a lot of infections that return.
How long does it take to get an actrema injection?
The infusion will take about 1 hour to give you the full dose of medicine.
Can ACTEMRA cause tears in the stomach?
Tell your healthcare provider if you have had diverticulitis (inflammation in parts of the large intestine) or ulcers in your stomach or intestines. Some people taking ACTEMRA get tears in their stomach or intestine. This happens most often in people who also take nonsteroidal anti-in flammatory drugs (NSAIDs ), corticosteroids , or methotrexate .
How to contact Genentech about Actemra?
Medicine Information Support. Ask about possible side effects and any other medical questions related to your prescribed Genentech medicine. Call us at (800) 821-8590, Monday-Friday, 5am-5pm PT. Chat with us using our live chat feature, Monday-Friday, 5am-5pm PT.
How to report side effects of Genentech?
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects to Genentech at 1-888-835-2555. Please see full Prescribing Information and the Medication Guide, including Serious Side Effects, for more Important Safety Information.
How old do you have to be to get PJIA?
To treat people with active polyarticular juvenile idiopathic arthritis (PJIA) 2 years of age and older
Can ACTEMRA cause multiple sclerosis?
While rare, Multiple Sclerosis has been diagnosed in people who take ACTEMRA.
Does actuma increase cancer risk?
ACTEMRA may increase your risk of certain cancers by changing the way your immune system works .
Can you get actherma if your neutrophils are low?
Changes in Blood Test Results. Your healthcare provider should do blood tests before and after you start receiving ACTEMRA. You should not receive ACTEMRA if your neutrophil and platelet counts are too low or your liver function test levels are too high.
Can you take actherma with diverticulitis?
If you have diverticulitis (inflammation in parts of the large intestine), talk to your healthcare provider before taking ACTEMRA. Some people taking ACTEMRA may develop a hole in the wall of their stomach or intestines (also known as a perforation).
Who makes ACTEMRA?
Food and Drug Administration. Medication Guide Revised: 03/2021 ACTEMRA is a registered trademark of Chugai Seiyaku Kabushiki Ka isha Corp., a member of the Roche Group.
Can you use ACTEMRA with a prefilled syringe?
Instructions for Use ACTEMRA (AC-TEM-RA) (tocilizumab) Injection, For Subcutaneous Use Single-dose Prefilled Syringe Do not remove the needle cap until you are ready to inject ACTEMRA.
How long does it take to get an actrema injection?
The infusion will take about 1 hour to give you the full dose of medicine.
Can ACTEMRA cause tears in the stomach?
Tell your healthcare provider if you have had diverticulitis (inflammation in parts of the large intestine) or ulcers in your stomach or intestines. Some people taking ACTEMRA get tears in their stomach or intestine. This happens most often in people who also take nonsteroidal anti-in flammatory drugs (NSAIDs ), corticosteroids , or methotrexate .
