Is afatinib chemo?
How Afatinib Works: Afatinib is not a chemotherapy drug but one of what are termed "targeted therapies." Targeted therapy is the result of years of research dedicated to understanding the differences between cancer cells and normal cells.
What are the side effects of afatinib?
Side EffectsBloody or cloudy urine.burning, dry, or itching eyes.difficult, burning, or painful urination.discharge or excessive tearing.frequent urge to urinate.redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid.redness, swelling, or pain of the skin.scaling of the skin on the hands and feet.More items...•
Is Gilotrif a chemotherapy?
Goals of therapy: Afatinib (Gilotrif®) is a chemotherapy drug taken to shrink lung cancer and to slow its progression to other areas of the body. Afatinib is also given to decrease symptoms such as cough, shortness of breath, and pain associated with non-small cell lung cancer.
How do you take a Gilotrif?
This medication comes in tablet form that you take by mouth once daily. Take this medication on an empty stomach, either 1 hour before or 2 hours after a meal. Take afatinib at around the same time every day. Take the tablet whole, do not break, crush or chew.
How long can you take afatinib?
Results: Patients prescribed afatinib had a significantly longer median duration of treatment compared with those prescribed erlotinib (12.1 vs 9.9 months; p = 0.035) and experienced a 14% reduction in risk of discontinuing therapy (adjusted hazard ratio: 0.86; CI: 0.75-0.99).
What is the best time to take afatinib?
Take this medicine on an empty stomach at least 1 hour before or 2 hours after a meal.Dosing. The dose of this medicine will be different for different patients. ... Missed Dose. If you miss a dose of this medicine, take it as soon as possible. ... Storage.
Is afatinib an immunotherapy?
We suggest that afatinib represents a second-line alternative treatment option for immunotherapy unfit advanced lung SCC patients. The role of EGFR-TKIs in the treatment of lung SCC without EGFR-activating mutations has been evaluated in several clinical trials.
How does afatinib work?
Afatinib (Gilotrif) belongs to a class of drugs known as tyrosine kinase inhibitors. It works by blocking the function of two closely related proteins, the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2).
Is afatinib cytotoxic?
Metformin Enhances TKI-Afatinib Cytotoxic Effect, Causing Downregulation of Glycolysis, Epithelial-Mesenchymal Transition, and EGFR-Signaling Pathway Activation in Lung Cancer Cells. Pharmaceuticals (Basel).
How do you pronounce afatinib?
Afatinib (pronounced aff-a-tin-ib) is a cancer treatment drug and is also known by its brand name Giotrif (pronounced jee-oh-triff).
What type of drug is afatinib?
Afatinib is in a class of medications called kinase inhibitors. It works by blocking the action of a certain naturally occurring substance that may be needed to help cancer cells multiply.
Is afatinib FDA approved?
On January 12, 2018, the Food and Drug Administration granted approval to afatinib (Gilotrif, Boehringer Ingelheim Pharmaceutical, Inc.)
Is afatinib an immunotherapy?
We suggest that afatinib represents a second-line alternative treatment option for immunotherapy unfit advanced lung SCC patients. The role of EGFR-TKIs in the treatment of lung SCC without EGFR-activating mutations has been evaluated in several clinical trials.
Is afatinib cytotoxic?
Metformin Enhances TKI-Afatinib Cytotoxic Effect, Causing Downregulation of Glycolysis, Epithelial-Mesenchymal Transition, and EGFR-Signaling Pathway Activation in Lung Cancer Cells. Pharmaceuticals (Basel).
Is afatinib FDA approved?
On January 12, 2018, the Food and Drug Administration granted approval to afatinib (Gilotrif, Boehringer Ingelheim Pharmaceutical, Inc.)
What is afatinib 30mg?
Generic Name: afatinib Afatinib is used to treat a certain type of lung cancer (non-small cell lung cancer). It belongs to a class of drugs known as kinase inhibitors. It works by slowing or stopping the growth of cancer cells. It binds to a certain protein (epidermal growth factor receptor-EGFR) in some tumors.
What is afatinib used for?
Gilotrif (afatinib) is a member of the multikinase inhibitors drug class and is commonly used for Non-Small Cell Lung Cancer.
How much does a free drug card save?
The free Drugs.com Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions.
Is gilotrif a generic?
Gilotrif is available as a brand name drug only, a generic version is not yet available. For more information, read about generic Gilotrif availability . This Gilotrif price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
