The Patient Assistance Program is for patients with no insurance coverage or lapsed coverage. This program offers free ALPHANATE or AlphaNine SD to uninsured who otherwise cannot afford their medications. Patients must meet financial and other program specific criteria to be eligible for assistance.
Full Answer
Why choose Alphanate?
ALPHANATE is designed to meet the needs of a variety of patients. 1 Since product launch in 1997, there has never been a confirmed case of virus or prion transmission with ALPHANATE. ALPHANATE is manufactured using 10 steps to safety with full traceability through the entire process from donor to patient.
Is Alphanate safe for patients with hemophilia A?
ALPHANATE is a trusted treatment for patients with hemophilia A or von Willebrand disease (VWD) 1. Since product launch in 1997, there has never been a confirmed case of virus or prion transmission with ALPHANATE.
What are the risks of Alphanate?
Because ALPHANATE is made from human plasma, it may carry a risk of transmitting infectious agents, eg, viruses, the variant Creutzfeldt-Jakob disease (vCJD) agent, and, theoretically, the Creutzfeldt-Jakob disease (CJD) agent, despite steps designed to reduce this risk. A comprehensive patient support and assistance program.
What does the $0 copay assistance program cover?
* The $0 Copay Assistance Program, which may cover out-of-pocket expenses not covered or partially covered by insurance, with no annual limits*† * Benefits investigation and support services to help patients coordinate with their insurer
What is Alphanate used for?from drugs.com
After administration, Alphanate temporarily replaces the missing coagulation factor VIII and von Willebrand factor needed for effective hemostasis.
What is the role of Alphanate in plasma?from drugs.com
Alphanate contains antihemophilic factor (FVIII) and von Willebrand factor (VWF), constituents of normal plasma. FVIII is an essential cofactor in activation of factor X leading to formation of thrombin and fibrin. VWF promotes platelet aggregation and platelet adhesion on damaged vascular endothelium; it also serves as a stabilizing carrier protein for the procoagulant protein FVIII. 12, 13
How many IU of Alphanate are needed for a child?from drugs.com
A total of 21 children (ages 7-16) were included in clinical trials with Alphanate. Subjects received Alphanate weekly for prophylaxis or suspected bleeds. They were successfully treated for 1499 bleeding episodes or as prophylaxis to prevent them (e.g. pain in the joint). The median number of units needed to treat the bleeds was 420 IU, with a range of 210 to 1620 IU. Adult and pediatric subjects did not differ in their response to treatment.
How long is alphanate stable?from drugs.com
Alphanate is stable for three years, up to the expiration date printed on its label, provided that the storage temperature does not exceed 25 °C (77 °F). Do not freeze.
How is alphanate prepared?from drugs.com
Alphanate is prepared from pooled human plasma by cryoprecipitation of FVIII, fractional solubilization, and further purification employ ing heparin-coupled, cross-linked agarose which has an affinity to the heparin binding domain of VWF/FVIII:C complex. The product is treated with a mixture of tri-n-butyl phosphate (TNBP) and polysorbate 80 to inactivate enveloped viruses. The product is also subjected to an 80 °C heat treatment step for 72 hours to inactivate enveloped and non-enveloped viruses. However, no procedure has been shown to be totally effective in removing viral infectivity from coagulation factor products.
What are the adverse reactions of alphanate?from drugs.com
Serious adverse drug reactions (ADRs) observed in patients receiving Alphanate include anaphylaxis/hypersensitivity reactions. Thromboembolic events also have been observed in patients receiving Alphanate for VWD [see Warnings and Precautions (5.3) ].
How many days of exposure to Alphanate?from drugs.com
In a prospective clinical study with Alphanate, 23 subjects were exposed to 1217 infusions (median=42, range 2-160). The total number of exposure days was 1133, and the total number of months on study across all subjects was 234 (19.5 subject years). No ADRs or inhibitors to FVIII were reported during the study.
Alphanate prices
The cost for Alphanate intravenous powder for injection - is around $11 for a supply of 1 powder for injection, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
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Alphanate Coupons and Rebates
Alphanate offers may be in the form of a printable coupon, rebate, savings card, trial offer, or free samples. Some offers may be printed right from a website, others require registration, completing a questionnaire, or obtaining a sample from the doctor's office.
Patient Assistance Programs for Alphanate
Patient assistance programs (PAPs) are usually sponsored by pharmaceutical companies and provide free or discounted medicines to low income or uninsured and under-insured people who meet specific guidelines. Eligibility requirements vary for each program.
How much does alphanate cost?from drugs.com
The cost for Alphanate intravenous powder for injection - is around $11 for a supply of 1 powder for injection, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
What are the most common adverse reactions to alpha nitrate?from alphanate.com
The most frequent adverse drug reactions reported with ALPHANATE in >1% of infusions were pruritus, headache, back pain, paresthesia, respiratory distress, facial edema, pain, rash, and chills.
What is Genentech Access to Care Foundation?from drugs.com
The Genentech Access to Care Foundation is now the Genentech Patient Foundation. Eligibility determined on a case-by-case basis. Call for most recent medications as the list is subject to change.
How to contact Genentech?from gene.com
Ask about possible side effects and any other medical questions related to your prescribed Genentech medicine. Call us at (800) 821-8590, Monday-Friday, 5am-5pm PT. Chat with us using our live chat feature, Monday-Friday, 5am-5pm PT. Email us by filling out this form. RESOURCES.
Do you have to tell your healthcare provider about all the medications you take?from gene.com
Patients must tell their healthcare provider about all the prescription and non-prescription medicines, vitamins and herbal supplements they take.
What is patient assistance?
The Patient Assistance Program is for patients with no insurance coverage or lapsed coverage. This program offers free ALPHANATE or AlphaNine SD to uninsured who otherwise cannot afford their medications. Patients must meet financial and other program specific criteria to be eligible for assistance. Eligibility criteria for Patient Assistance
How many IUs of Alphanine SD can you get for free?
You can request up to 3 total doses with a maximum of 12,000 IUs through this Free Trial program. Eligibility criteria for Free Trial
Can you get copay assistance with Medicare?
Patients' health plan permits members to participate in copay assistance programs. Patients are ineligible for copay assistance if they participate in Medicare, Medicaid, Medigap, Veterans Affairs, Department of Defense, Tricare, or any other federal or state-funded programs.
How fast can you take Alphanine?
AlphaNine SD should not be administered at a rate exceeding 10 mL/ minute. Rapid administration may result in vasomotor reactions.
What is Alphanine SD made of?
AlphaNine SD is made from human plasma. Plasma products carry a risk of transmitting infectious agents, including viruses, and theoretically, the Creutzfeldt-Jakob disease (CJD) agent, despite steps designed to reduce this risk.
Important Note
- The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug. ANTIHEMOPHILIC FACTOR, HUMAN - INJECTIO…
Uses
- Antihemophilic factor is a protein in the blood necessary in forming clots to stop bleeding. This medication is used to temporarily prevent or control bleeding episodes in patients with hemophilia A.
How to Use
- This medication is given by injection into a vein. The rate of injection depends upon patient response but is generally injected over 5 to 10 minutes. The powder and dissolving fluid should be warmed to room temperature before combining if they were refrigerated. After adding the dissolving fluid, swirl the vial gently to completely dissolve the powder. Do not use the mixed sol…
Side Effects
- This medication is generally well tolerated. Mild chills, nausea and irritation at the injection site may occur. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed a...
Precautions
- Tell your doctor your medical history, especially of: other illnesses, any allergies (especially to animal proteins). Because this medication is prepared from human blood, there is a risk of contracting a virus from using this. Careful screening of blood donors, special manufacturing methods and FDA-approved tests are all used to reduce this risk. Discuss this with your doctor. …
Drug Interactions
- Tell your doctor of all over-the-counter and prescription medications you may use. Do not start or stop any medicine without doctor or pharmacist approval.
Overdose
- If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include unusual tiredness; easy bleeding or bruising; or yellowing eyes or skin.
Notes
- Blood tests will be done frequently to determine dosing and evaluate the effectiveness of this medication.
Missed Dose
- It is important that each dose be used as directed. If you miss a dose, contact your doctor to establish a new dosing schedule. Do not "double-up" the dose to catch up.
Storage
- Store the medication according to manufacturer's instructions. Check the expiration date on the label and properly discard any unused medication after that time.