What is Ambisome Support Solutions?
What is the phone number for Ambisome?
How much does liposomal amphotericin B cost?
The cost for amphotericin b intravenous powder for injection 50 mg is around $56 for a supply of 1 powder for injection, depending on the pharmacy you visit....Intravenous Powder For Injection.QuantityPer unitPrice1$55.94$55.94
What is the ideal infusion time for AmBisome?
AmBisome should be administered by intravenous infusion over a 30 - 60 minute period. For doses greater than 5mg/kg/day, intravenous infusion over a 2 hour period is recommended (see section 4.4).
What is the cost of amphotericin B?
Company stated that NPPA notified the ceiling price of Amphotericin B (Liposomal) Injection 50mg as Rs. 3402.55 per pack vide S.O. 269 (E) dated 16.01.
Who manufactures AmBisome?
AmBisome® is a registered trademark of Gilead Sciences, Inc.
What is the major downside to long term treatment with amphotericin B?
The major drawback of the conventional amphotericin B is its nephrotoxicity.
What drugs should not be taken with amphotericin?
Some products that may interact with this drug include: anti-cancer drugs (such as mechlorethamine, nitrogen mustard), azole antifungals (such as ketoconazole, itraconazole), cidofovir, digoxin, flucytosine, medications that affect the kidneys (including pentamidine, tacrolimus, aminoglycosides such as gentamicin), ...
How long is amphotericin B treatment?
Mean duration of treatment with liposomal amphotericin B was 20 +/- 20 days, at an average dose of 2.3 mg/kg/d.
What is the difference between amphotericin B and liposomal amphotericin?
Liposomal amphotericin B provides an equally efficacious alternative to conventional amphotericin B deoxycholate in patients with AIDS and acute cryptococcal meningitis. Liposomal amphotericin B at a dosage of 3 mg/kg/day is accompanied by significantly fewer adverse effects.
Is AmBisome refrigerated?
Prior to reconstitution Amphotericin B Intravenous should be stored in the refrigerator, protected against exposure to light. The reconstituted solution may be stored in the dark, at room temperature for 24 hours, or at refrigerator temperatures for 1 week with minimal loss of potency and clarity.
What is the difference between amphotericin B and AmBisome?
These results suggest that AmBisome® is an effective and safe antifungal agent in the treatment of systemic candidiasis in VLBWI. The mean duration of AmBisome® therapy was shorter than amphotericin B therapy, but fungal eradication rates, eradication time, and mortality rates were similar.
Is AmBisome generic?
February 15, 2022 - Sun Pharmaceuticals launched an AB-rated generic version of Astellas' Ambisome (amphotericin B) liposome for injection.
Who makes amphotericin B in USA?
Sun Pharmaceuticals Industries announced that one of its wholly-owned subsidiaries has received final approval from US FDA for its Abbreviated New Drug Application (ANDA) for generic Amphotericin B Liposome for Injection, 50 mg/vial Single-Dose Vial.
How do you administer IV amphotericin?
How should this medicine be used? Amphotericin B injection comes as a solid powder cake to be made into a solution and then injected intravenously (into a vein) by a nurse or a doctor. Amphotericin B injection is usually infused (injected slowly) intravenously over a period of 2 to 6 hours once daily.
How long is amphotericin B treatment?
Mean duration of treatment with liposomal amphotericin B was 20 +/- 20 days, at an average dose of 2.3 mg/kg/d.
How do you reconstitute AmBisome?
Vial Reconstitution:Aseptically add 12 mL of Sterile Water for Injection, USP to each AmBisome vial to yield a preparation containing 4 mg amphotericin B/mL. ... Immediately after the addition of water, SHAKE THE VIAL VIGOROUSLY for 30 seconds to completely disperse the AmBisome.More items...•
What is the difference between amphotericin B and AmBisome?
These results suggest that AmBisome® is an effective and safe antifungal agent in the treatment of systemic candidiasis in VLBWI. The mean duration of AmBisome® therapy was shorter than amphotericin B therapy, but fungal eradication rates, eradication time, and mortality rates were similar.
Important Note
The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.
Uses
This medication is used in the treatment of certain fungal infections.
How To Use
This medication is administered by infusion into a vein by a health care professional. It is usually given once a day over 1 to 3 hours. It may be necessary to continue therapy with this medication for several weeks to months in certain cases. Stopping therapy too soon may result in ineffective treatment.
Side Effects
Fever and chills may occur 1 to 2 hours after the infusion is started. This is more common with the first few doses and should subside as therapy continues. Nausea, headache and irritation at the injection site may also occur. To help minimize these effects, you may be given a pain reliever or other medication before each dose.
Precautions
Tell your doctor your medical history, especially of: heart disease, liver disease, kidney disease, any allergies. This medication should be used only if clearly needed during pregnancy. Use of this medication is not recommended while breast-feeding. Discuss the risks and benefits with your doctor.
Drug Interactions
Tell your doctor of all nonprescription or prescription medication you may take, particularly: steroids, digoxin, cyclosporine, zidovudine, pentamidine, aminoglycoside antibiotics, cancer medications, tacrolimus, other antifungals. Do not start or stop any medicine without doctor or pharmacist approval.
Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately.
How much does Ambisome cost?
AmBisome Prices. The cost for AmBisome intravenous powder for injection 50 mg is around $289 for a supply of 1 powder for injection, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
What is an ambsome offer?
AmBisome offers may be in the form of a printable coupon, rebate, savings card, trial offer, or free samples. Some offers may be printed right from a website, others require registration, completing a questionnaire, or obtaining a sample from the doctor's office.
What drugs interact with Ambisome?
However, the following drugs are known to interact with amphotericin B and may interact with AmBisome: antineoplastic agents, corticosteroids and corticotropin (ACTH), digitalis glycosides, flucytosine, azoles (e.g. ketoconazole, miconazole, clotrimazole, fluconazole), leukocyte transfusions, other nephrotoxic medications , and skeletal muscle relaxants. (Please see Package Insert, Drug Interactions)
What is the Am B isome?
Am B isome is indicated for the following: Treatment of patients with Aspergillus species, Candida species, and/or Cryptococcus species infections refractory to amphotericin B deoxycholate, or in patients where renal impairment or unacceptable toxicity precludes the use of amphotericin B deoxycholate. Treatment of visceral leishmaniasis.
What are the adverse events of Am B isome?
In the clinical study noted above, common adverse events occurring at an incidence of 10% or more and more frequently in patients taking Am B isome compared to those taking Abelcet include: abdominal pain, sepsis, transfusion reaction, chest pain, diarrhea, bilirubinemia, edema, hypocalcemia, hypokalemia, hypomagnesemia, anxiety, confusion, headache, and rash
Which isome group had higher discontinuation rates?
Treatment discontinuations due to an adverse event were higher among patients in the Abelcet group than in the Am B isome groups
What tests should be included in patient management?
Laboratory Tests: Patient management should include laboratory evaluation of renal, hepatic, and hematopoietic function, and serum electrolytes (magnesium and potassium).
Is Am B isome contraindicated?
Am B isome is contraindicated in those patients who have demonstrated or have a known hypersensitivity to amphotericin B deoxycholate or any other constituents of the product, unless benefit of therapy outweighs the risk.
Is amphotericin B deoxycholate refractory to aspergillus?
Treatment of patients with Aspergillus species, Candida species, and/or Cryptococcus species infections refractory to amphotericin B deoxycholate, or in patients where renal impairment or unacceptable toxicity precludes the use of amphotericin B deoxycholate
Summary
Astellas Pharma Inc. was establish in Japan on April 1st, 2005. Astellas Pharma Inc. formed through the merger of Yamanouchi Pharmaceutical Co., Ltd. (founded in Osaka, Japan, 1923) and FujisawaPharmaceutical Co., Ltd. (founded in Osaka, Japan, 1894). As a new pharmaceutical company, Astellas Pharma Inc.
Eligibility
Astellas Stock Replacement Program For AmBisome, a patient assistance program provided by Astellas Pharma Inc., offers AmBisome at no cost to those who are eligible for the program. Eligibility is based off of the following requirements:
How do I apply for the Ambisome patient assistance program?
Our application process aims to make it as easy as possible to apply for the Ambisome patient assistance program. The first step is to complete our online enrollment application. We will ask you for details about your healthcare provider, your insurance plan, and your household income as this information is required by the pharmaceutical companies. We may be able to help you apply for other patient assistance programs too, so be sure to tell us about any medications you are taking as well as Ambisome.
What is Ambisome used for?
Ambisome is classed as an antifungal and is used for the treatment of serious life-threatening infections such as leishmaniasis or certain types of meningitis in people who have HIV (human immunodeficiency virus).
Can NiceRx help me get Ambisome if I have insurance?
NiceRx may be able to help you if your insurance company will not pay for your Ambisome medication. We may also be able to help if you have a high copay or coinsurance responsibility. Whether you have insurance or not, apply online using our enrollment application to find out more.
Is NiceRx an Ambisome coupons provider?
NiceRx is a service provider that helps eligible individuals access the Ambisome patient assistance program. We do not offer trial offers or free Ambisome samples. When obtaining your medication through NiceRx, you will only pay $49 a month per medication. This will likely save you more money than if you were to use Ambisome coupons, discount cards, or Ambisome copay cards.
What is BI Cares?
The BI Cares Patient Assistance Program is a charitable program provided by the Boehringer Ingelheim Cares Foundation (BI Cares), an independent nonprofit organization, to improve patients’ health and lives.
Is Boehringer Ingelheim Cares affiliated with any third party?
The Boehringer Ingelheim Cares Foundation is not affiliated with any third party individual or organization that may charge patients a fee (s) to assist them in applying to our program or ordering refills through our program. These individuals or organizations are acting independently of the Boehringer Ingelheim Cares Foundation and do not have the Foundation’s consent.
Important Note
The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.
Uses
This medication is used in the treatment of certain fungal infections.
How To Use
This medication is administered by infusion into a vein by a health care professional. It is usually given once a day over 1 to 3 hours. It may be necessary to continue therapy with this medication for several weeks to months in certain cases. Stopping therapy too soon may result in ineffective treatment.
Side Effects
Fever and chills may occur 1 to 2 hours after the infusion is started. This is more common with the first few doses and should subside as therapy continues. Nausea, headache and irritation at the injection site may also occur. To help minimize these effects, you may be given a pain reliever or other medication before each dose.
Precautions
Tell your doctor your medical history, especially of: heart disease, liver disease, kidney disease, any allergies. This medication should be used only if clearly needed during pregnancy. Use of this medication is not recommended while breast-feeding. Discuss the risks and benefits with your doctor.
Drug Interactions
Tell your doctor of all nonprescription or prescription medication you may take, particularly: steroids, digoxin, cyclosporine, zidovudine, pentamidine, aminoglycoside antibiotics, cancer medications, tacrolimus, other antifungals. Do not start or stop any medicine without doctor or pharmacist approval.
Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately.
What is Ambisome Support Solutions?
AmBisome Support Solutions, a component of Astellas Pharma Support Solutions SM, offers access and reimbursement support to help patients overcome challenges to accessing AmBisome ® (amphotericin B) liposome for injection. AmBisome Support Solutions provides information regarding patient healthcare coverage options and financial assistance options that may be available to help patients with financial needs.
What is the phone number for Ambisome?
To speak with a dedicated access specialist, please call us at 1-800-477-6472. We are available Monday–Friday, 9:00 am–8:00 pm ET.
Important Note
- The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug. AMPHOTERICIN/LIPID COMPLEX INJECTION (a…
How to Use
- This medication is administered by infusion into a vein by a health care professional. It is usually given once a day over 1 to 3 hours. It may be necessary to continue therapy with this medication for several weeks to months in certain cases. Stopping therapy too soon may result in ineffective treatment.
Side Effects
- Fever and chills may occur 1 to 2 hours after the infusion is started. This is more common with the first few doses and should subside as therapy continues. Nausea, headache and irritation at the injection site may also occur. To help minimize these effects, you may be given a pain reliever or other medication before each dose. If the side effects ...
Precautions
- Tell your doctor your medical history, especially of: heart disease, liver disease, kidney disease, any allergies. This medication should be used only if clearly needed during pregnancy. Use of this medication is not recommended while breast-feeding. Discuss the risks and benefits with your doctor.
Drug Interactions
- Tell your doctor of all nonprescription or prescription medication you may take, particularly: steroids, digoxin, cyclosporine, zidovudine, pentamidine, aminoglycoside antibiotics, cancer medications, tacrolimus, other antifungals. Do not start or stop any medicine without doctor or pharmacist approval.
Notes
- This medication is usually given in the hospital setting where your condition and response can be closely monitored. Laboratory tests and blood counts will be done routinely while using this to monitor its effects and prevent side effects.
Missed Dose
- It is important to use each dose as scheduled. If you miss a dose, contact your health care provider who will help establish a new dose schedule. Do not "double-up" the dose to catch up.