Patient Assistance Programs for Ambrisentan. Patient assistance programs (PAPs) are usually sponsored by pharmaceutical companies and provide free or discounted medicines to low income or uninsured and under-insured people who meet specific guidelines. Eligibility requirements vary for each program. There are currently no Patient Assistance Programs that we know about for this drug.
Full Answer
What is the ambrisentan co-pay card program?
The AMBRISENTAN Co-Pay Card Program can help with your out-of-pocket costs. Eligible patients who have commercial insurance, may pay no more than a $5 co-pay per prescription. The program provides co-pay assistance of up to $100 for 30-day prescriptions, up to $1,200 a year. For PS-AMBRISENTAN REMS information, click here.
What type of drug is ambrisentan?
Ambrisentan is an oral medication classified as an endothelin receptor antagonist (ERA) which is approved for the treatment of pulmonary arterial hypertension (PAH) in World Health Organization (WHO) Group 1 patients.
Can ambrisentan be purchased at a local pharmacy?
Ambrisentan is a limited distribution medication, which means it cannot be purchased at a local pharmacy. It must be prescribed by a physician through the Letairis® Education and Access Program (LEAP) and insurance approval must be obtained prior to starting therapy. LEAP will forward the request to a specialty pharmacy.
What is the ambrisentan REMS program?
The Ambrisentan REMS is a safety program that manages the risk of serious birth defects when taking ambrisentan. The Ambrisentan REMS is required by the Food and Drug Administration (FDA). Only prescribers and pharmacies certified by the Ambrisentan REMS can prescribe and dispense ambrisentan to patients.
Is patient assistance program legitimate?
Patient assistance programs (PAPs) are usually sponsored by pharmaceutical manufacturers and are promoted as a safety net for Americans who have no health insurance or are underinsured.
How long does it take for ambrisentan to work?
How long does it take for ambrisentan (Letairis) to work? Most people will start to notice better exercise ability after taking ambrisentan (Letairis) for one month. It can take up to three months to notice the full effects of this medication.
What is ambrisentan used for?
Ambrisentan is used alone or in combination with tadalafil (Adcirca, Cialis) to treat pulmonary arterial hypertension (PAH, high blood pressure in the vessels that carry blood to the lungs). Ambrisentan may improve the ability to exercise and slow the worsening of symptoms in people with PAH.
Is ambrisentan FDA approved?
The US Food and Drug Administration (FDA) has approved four generic versions of Gilead Sciences' Letairis (ambrisentan), an endothelin receptor antagonist indicated for treatment for pulmonary arterial hypertension (PAH).
Is there a generic for ambrisentan?
On April 11, 2019, Sun launched an AB-rated generic version of Gilead Sciences' Letairis (ambrisentan) tablets. — Mylan, Teva, Zydus, Par, and Sigmapharm received FDA approval of AB-rated generic versions of Letairis.
Does ambrisentan lower BP?
What Is Letairis? Letairis (ambrisentan) is an endothelin receptor antagonist used to treat pulmonary arterial hypertension (PAH). Letairis blocks the effects of endothelin-1, helping to decrease the blood pressure in the lungs, slow the worsening of symptoms, and improve your ability to exercise.
What are the side effects of ambrisentan?
Incidence not knownChest pain.clay colored stools.decrease in the amount of urine.decreased appetite.dilated neck veins.extreme tiredness or weakness.irregular breathing.large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals.More items...•
What is another name for ambrisentan?
Ambrisentan (U.S. trade name Letairis; E.U. trade name Volibris; India trade name Pulmonext by MSN labs) is a drug indicated for use in the treatment of pulmonary hypertension. The peptide endothelin constricts muscles in blood vessels, increasing blood pressure.
Does ambrisentan cause anemia?
Results from the VOLT post-marketing program confirmed the safety profile of ambrisentan observed in the ARIES studies, including the low incidence of liver function test abnormalities. Peripheral edema and anemia were common side effects of endothelin receptor antagonist therapies, including ambrisentan.
Who is the manufacturer of ambrisentan?
Ambrisentan is a potent selective endothelin A receptor antagonist, developed by Gilead Sciences and GlaxoSmithKline, for the treatment of pulmonary arterial hypertension (PAH) and idiopathic pulmonary fibrosis.
What is the brand name of tadalafil?
you should know that tadalafil is available under the brand names Adcirca and Cialis. You should only be treated with one of these products at a time. tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take.
What is the brand name for bosentan?
Bosentan, sold under the brand name Tracleer and Safebo among others, is a dual endothelin receptor antagonist medication used in the treatment of pulmonary artery hypertension (PAH). Bosentan is available as film-coated tablets (62.5 mg or 125 mg) or as dispersable tablets for oral suspension (32 mg).
What are the side effects of ambrisentan?
Incidence not knownChest pain.clay colored stools.decrease in the amount of urine.decreased appetite.dilated neck veins.extreme tiredness or weakness.irregular breathing.large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals.More items...•
Can you crush ambrisentan?
Swallow the tablet whole. Do not crush, break, or chew it. You may take this medicine with or without food.
What is another name for ambrisentan?
Ambrisentan (U.S. trade name Letairis; E.U. trade name Volibris; India trade name Pulmonext by MSN labs) is a drug indicated for use in the treatment of pulmonary hypertension. The peptide endothelin constricts muscles in blood vessels, increasing blood pressure.
What is tadalafil 20 mg used for?
Tadalafil is a medicine used to treat erection problems (erectile dysfunction) and symptoms of an enlarged prostate (benign prostate enlargement). It's also sometimes used to treat pulmonary hypertension (high blood pressure in the blood vessels that supply the lungs). Tadalafil is available on prescription only.
How much ambrisentan is there?
Ambrisentan is taken orally, with or without food. There are two FDA approved doses; 5 mg (pale pink and square) or 10 mg (dark pink and oval). Patients’ physicians will decide which strength is right for them.
How does ambrisentan work?
Ambrisentan works by blocking endothelin, a substance made by the body. Endothelin causes blood vessels to narrow (constrict). It also causes abnormal growth of the muscle in the walls of the blood vessels in the lungs. This narrowing increases the pressure required to push the blood through the lungs to get oxygen.
What is Ambrisentan used for?
The goal of this therapy is to improve exercise ability and slow progression of the disease.
What is the difference between Ambrisentan 5 mg and 10 mg?
Ambrisentan comes in 5 and 10 mg, film-coated, unscored tablets. The 5 mg tablet is pale pink and square. The 10 mg tablet is deep pink and oval.
When was Ambrisentan approved for PAH?
Ambrisentan was approved for PAH by the United States Food and Drug Administration (FDA) in 2007.
Why do women have to have a pregnancy test before taking ambrisentan?
Because of the potential harm to the fetus, women must have a pregnancy test before initiating therapy, and every month while they are receiving ambrisentan.
Is ambrisentan safe for children?
There has not been research to determine whether ambrisentan is safe or effective for children.
What is the medication for pulmonary arterial hypertension?
Letairis (ambrisentan) is a prescription medicine used to treat pulmonary arterial hypertension (PAH), which is high blood pressure in the arteries of the lungs.
Who should not take Letairis?
You are pregnant, plan to become pregnant, or become pregnant while taking Letairis. Letairis can cause serious birth defects. (See "What is the most important information I should know about Letairis?")
What should I tell my doctor before taking Letairis?
All your medical conditions. Be sure to tell your doctor if you have a low red blood cell level (anemia) or liver problems
What are the other possible side effects of Letairis?
Tell your doctor right away if you have any unusual weight gain, tiredness, or trouble breathing while taking Letairis. These may be symptoms of a serious health problem. You may need to be treated with medicine or need to go to the hospital
Does ambrisentan affect sperm count?
Decreased sperm counts have been observed in patients taking endothelin receptor antagonists and in animal fertility studies with ambrisentan. Counsel patients about potential effects on fertility
Do female patients have to enroll in Letairis?
All female patients , regardless of reproductive potential, must enroll in the Letairis REMS Program
Is Letairis safe for hepatic impairment?
Hepatic impairment: Letairis is not recommended in patients with moderate or severe hepatic impairment. Fully investigate cause of liver injury in patients who develop hepatic impairment; discontinue Letairis if liver aminotransferases are >5x ULN or if elevations are accompanied by bilirubin >2x ULN, or by signs or symptoms of liver dysfunction and other causes are excluded
What to do if you take more than your usual dose of ambrisentan?
If you take more than your regular dose of ambrisentan tablets, call your doctor right away.
What is the purpose of ambrisentan?
Ambrisentan tablets are indicated for the treatment of pulmonary arterial hypertension (PAH) (WHO Group 1):#N#• To improve exercise ability and delay clinical worsening.#N#Studies establishing effectiveness included predominantly patients with WHO Functional Class II–III symptoms and etiologies of idiopathic or heritable PAH (60%) or PAH associated with connective tissue diseases (34%).
Can Ambrisentan cause side effects?
Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Ambrisentan tablets and other medicines may affect each other, causing side effects. Do not start any new medicines until you check with your doctor.
Can you stop taking Ambrisentan?
Take ambrisentan tablets exactly as your doctor tells you to take it. Do not stop taking ambrisentan tablets unless your doctor tells you to stop.
Does Ambrisentan help with physical symptoms?
Ambrisentan tablets can improve your ability to exercise and it can help slow down the worsening of your physical condition and symptoms.
Can you breastfeed if you take Ambrisentan?
If you miss a menstrual period, or think you might be pregnant, call your doctor right away./li>. It is not known if ambrisentan passes into your breast milk. You should not breastfeed if you are taking ambrisentan tablets. Talk to your doctor about the best way to feed your baby if you take ambrisentan tablets.
Can ambrisentan cause a lot of fluid retention?
Swelling all over the body (fluid retention) can happen within weeks after starting ambrisentan tablets. Tell your doctor right away if you have any unusual weight gain, tiredness, or trouble breathing while taking ambrisentan tablets. These may be symptoms of a serious health problem. You may need to be treated with medicine or need to go to the hospital.
How much does Letairis cost?
Patients who have commercial insurance may pay as little as $5 per month for Letairis. Eligible patients are automatically enrolled when they are prescribed branded Letairis.
Who should not take Letairis?
You are pregnant, plan to become pregnant, or become pregnant while taking Letairis. Letairis can cause serious birth defects. (See "What is the most important information I should know about Letairis?")
What are the other possible side effects of Letairis?
Tell your doctor right away if you have any unusual weight gain, tiredness, or trouble breathing while taking Letairis. These may be symptoms of a serious health problem. You may need to be treated with medicine or need to go to the hospital
What is the medication for pulmonary arterial hypertension?
Letairis (ambrisentan) is a prescription medicine used to treat pulmonary arterial hypertension (PAH), which is high blood pressure in the arteries of the lungs. How LEAP Can HelpFinancial Resources. Stay on track with supportSupport from LEAP is only available with . branded Letairis.
Who should not take Letairis?
You are pregnant, plan to become pregnant, or become pregnant while taking Letairis. Letairis can cause serious birth defects. (See "What is the most important information I should know about Letairis?")
What should I tell my doctor before taking Letairis?
All your medical conditions. Be sure to tell your doctor if you have a low red blood cell level (anemia) or liver problems
How long does it take for a fluid to reappear after taking Letairis?
Swelling all over the body (fluid retention) can happen within weeks after starting Letairis. Tell your doctor right away if you have any unusual weight gain, tiredness, or trouble breathing while taking Letairis. These may be symptoms of a serious health problem. You may need to be treated with medicine or need to go to the hospital
Does Letairis help with physical symptoms?
Letairis can improve your ability to exercise and it can help slow down the worsening of your physical condition and symptoms
What is the number to call for Letairis?
If your patients are struggling to cover out-of-pocket costs or have no insurance at all, encourage them to call 1-866-664-5327 to explore possible support options. Learn more about how LEAP can help. Start a patient on Letairis. Review clinical results.
Does ambrisentan affect sperm count?
Decreased sperm counts have been observed in patients taking endothelin receptor antagonists and in animal fertility studies with ambrisentan. Counsel patients about potential effects on fertility
Is Letairis safe for hepatic impairment?
Hepatic impairment: Letairis is not recommended in patients with moderate or severe hepatic impairment. Fully investigate cause of liver injury in patients who develop hepatic impairment; discontinue Letairis if liver aminotransferases are >5x ULN or if elevations are accompanied by bilirubin >2x ULN, or by signs or symptoms of liver dysfunction and other causes are excluded
