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aprepitant patient assistance

by Nick Yundt Published 2 years ago Updated 1 year ago
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Patient Assistance & Copay Programs for Aprepitant Patient assistance programs (PAPs) are usually sponsored by pharmaceutical companies and provide free or discounted medicines and copay programs to low income or uninsured and under-insured people who meet specific guidelines. Eligibility requirements vary for each program.

Full Answer

Can aprepitant be used to treat nausea and vomiting?

Aprepitant is not typically used to treat nausea and vomiting. When a medicine is given to prevent nausea and vomiting, it is known as prophylaxis, or prophylactic anti-emetic therapy. How is aprepitant (Emend®) given to prevent nausea and vomiting?

How does aprepitant work?

Aprepitant is designed to block receptors in your brain called substance P/neurokinin 1 (NK 1) receptors which, when activated, can trigger nausea and vomiting. Depending upon the type of chemotherapy, certain types may contribute to substance P being released.

How much does aprepitant cost?

The cost for aprepitant oral capsule 40 mg is around $86 for a supply of 1 capsules, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans. This aprepitant price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.

Can I get a co-pay card for aprepitant?

Aprepitant (Emend®) For Branded medications (may be available for generic medications too), check with the manufacturer to determine if a co-pay card is offered and if it could reduce your monthly copay. If you are uninsured, check with the manufacturer to determine if you are eligible to receive medication at no cost.

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Does Merck have a patient assistance program?

The Merck Patient Assistance Program provides certain medicines and adult vaccines free of charge to eligible individuals who do not have insurance or whose insurance does not cover their prescription Merck products.

Who makes Emend?

Merck Sharp & Dohme Corp.EMEND is a registered trademark of Merck Sharp & Dohme Corp.

How do you qualify for free eliquis?

You may be eligible for the Free 30-Day Trial Offer for ELIQUIS® (apixaban) if:You have not previously filled a prescription for ELIQUIS;You have a valid 30-day prescription for ELIQUIS;You are being treated with ELIQUIS for an FDA-approved indication that an HCP has planned for more than 35 days of treatment;More items...

What pharmaceutical company makes Janumet?

With JANUVIA, JANUMET, JUVISYNC (sitagliptin and simvastatin) and now JANUMET XR, Merck has a growing family of products that provides physicians with important treatment options for patients with type 2 diabetes.

How much is Emend cost?

It is typically used in adults and children to prevent nausea and vomiting caused by cancer chemotherapy and is sometimes prescribed off-label to prevent nausea and vomiting that may be caused by surgery. The generic version of Emend is aprepitant. The cash price of Emend is about $524.86.

Is there a generic for Emend?

GENERIC NAME: APREPITANT - ORAL (a-PRE-pi-tant)

How much does Eliquis cost at Walmart?

The cost of Eliquis is $695.91 for 60, 5MG Tablet, but you can use an Eliquis coupon below to pay $459.24 per 60, 5mg Tablet....Average 12 Month Prices for Eliquis.PharmacyEliquis Retail PriceEliquis SingleCare PriceWalmart$601.08$528.01Walgreens$623.72$537.78Kroger Pharmacy$624.91$487.613 more rows

What is a cheaper alternative to Eliquis?

You can always consider speaking to your provider to see if another, cheaper medication will be as effective as Eliquis for you. Similar anticoagulant medications to Eliquis include: Warfarin (Coumadin, Jantoven): Warfarin is a generic drug that is comparable with Eliquis but costs significantly less – as little as $4.

Does Bristol Myers Squibb have a patient assistance program?

The Bristol Myers Squibb Patient Assistance Foundation (BMSPAF) is an independent, charitable organization that helps eligible patients who need temporary help obtaining the medicines listed on this website.

How much does Janumet cost at Walmart?

Average 12 Month Prices for JanumetPharmacyJanumet Retail PriceJanumet SingleCare PriceWalmart$605.80$425.79Walgreens$672.31$442.23Kroger Pharmacy$651.58$377.66Albertsons Pharmacy$611.73$364.752 more rows

How expensive is Janumet?

The lowest GoodRx price for the most common version of Janumet is around $520.21, 17% off the average retail price of $629.00.

Is Janumet still on the market?

Many of these Januvia and Janumet patients developed acute pancreatitis shortly after starting the drugs or changing dosage. Over half of the cases resolved after Januvia and Janumet were discontinued.

How long does it take for Emend to work?

Take the first dose as directed by your doctor, usually 1 hour before the start of chemotherapy. For the next 2 days, continue to take a dose once daily 1 hour before the start of treatment if you are getting chemotherapy that day. If you are not getting any chemotherapy, then take the dose once daily in the morning.

What is a Emend?

Emend is an antiemetic, a medicine that prevents nausea (feeling sick) and vomiting. Emend is used in patients aged from 6 months to prevent nausea and vomiting caused by chemotherapy (medicines used to treat cancer). It is used with chemotherapy that is a moderate or strong trigger of nausea and vomiting.

When is aprepitant taken?

On days when chemotherapy is given and a dose of aprepitant is to be taken, aprepitant is usually brought from home and taken at the infusion center, approximately one hour prior to treatment. On days when a dose of aprepitant is to be taken but no chemotherapy is given, aprepitant is usually taken at home in the morning.

Why is the exact percentage of patients that will experience aprepitant side effects unknown?

Note : The exact percentages of patients that will experience aprepitant side effects is unknown because it has been used under widely varying patient populations in a variety of clinical trials

What is apepitant capsule?

Aprepitant capsules are given to prevent both early and delayed nausea and vomiting (also known as “emesis”) from chemotherapy and is commonly given on a scheduled basis. Aprepitant is not typically used to treat nausea and vomiting. When a medicine is given to prevent nausea and vomiting, it is known as prophylaxis, or prophylactic anti-emetic therapy.

What is the effect of aprepitant on the brain?

Aprepitant is designed to block receptors in your brain called substance P/neurokinin 1 (NK 1) receptors which, when activated, can trigger nausea and vomiting.

How many capsules are in a apropitant?

Aprepitant is commonly dispensed as a “Tri-Pack” that contains one 125 mg capsule labeled as “Day 1” and two 80 mg capsules, one of which is labeled “Day 2” and the other as “Day 3”. Be sure you are taking the correct dosage on the correct day.

Why should a pharmacist review your medication list?

A pharmacist should ALWAYS review your medication list to ensure that drug interactions are prevented or managed appropriately

Why is it important to understand your treatment?

A better understanding of your treatments will allow you to ask more questions of your healthcare team. We then hope that with the answers, you will get better results and have greater satisfaction with your care. Because we know it's not always easy to know what questions to ask, we've tried to make it easy for you!

Drug Company Assistance

The Merck Helps website assists qualified patients receive free or discounted medications through several patient assistance programs.

Foundation Assistance

ASH has not located any foundations that specifically offer assistance for patients requiring aprepitant. If you know of a program or foundation, please contact ASH Policy and Practice Coordinator, Deon Nelson.

How is aprepitant metabolized?from drugs.com

Aprepitant undergoes extensive metabolism. In vitro studies using human liver microsomes indicate that aprepitant is metabolized primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19. Metabolism is largely via oxidation at the morpholine ring and its side chains. No metabolism by CYP2D6, CYP2C9, or CYP2E1 was detected. In healthy young adults, aprepitant accounts for approximately 24% of the radioactivity in plasma over 72 hours following a single oral 300-mg dose of [ 14 C]-aprepitant (2.4 times the maximum Emend recommended dose), indicating a substantial presence of metabolites in the plasma. Seven metabolites of aprepitant, which are only weakly active, have been identified in human plasma.

How to apply for Merck patient assistance?from merckhelps.com

If you believe that you meet the eligibility criteria for the Merck Patient Assistance Program and you have received a prescription for a Merck product, call toll-free 800-727-5400 8 AM to 8 PM ET to obtain a brochure outlining the program and an enrollment application, or by clicking on the link on the right. After downloading the application or receiving your packet in the mail, follow these simple steps to submit your enrollment form for your free Merck medicines:

What is apepitant antagonist?from drugs.com

Aprepitant is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK 1) receptors. Aprepitant has little or no affinity for serotonin (5-HT 3 ), dopamine, and corticosteroid receptors, the targets of existing therapies for chemotherapy-induced nausea and vomiting (CINV).

Does fosaprepitant affect QTC?from drugs.com

In a randomized, double-blind, positive-controlled, thorough QTc study, a single 200-mg dose of fosaprepitant had no effect on the QTc interval. Maximum aprepitant concentrations after a single 200-mg dose of fosaprepitant were 4-fold higher than that achieved with oral Emend 125 mg. QT prolongation with the recommended oral Emend dosing regimens is not expected.

Does aprepitant inhibit emesis?from drugs.com

Aprepitant has been shown in animal models to inhibit emesis induced by cytotoxic chemotherapeutic agents, such as cisplatin, via central actions. Animal and human Positron Emission Tomography (PET) studies with aprepitant have shown that it crosses the blood brain barrier and occupies brain NK 1 receptors. Animal and human studies show that aprepitant augments the antiemetic activity of the 5-HT 3 -receptor antagonist ondansetron and the corticosteroid dexamethasone and inhibits both the acute and delayed phases of cisplatin-induced emesis.

Is aprepitant a pharmacokinetic drug?from drugs.com

No dosage adjustment is necessary for patients with mild to moderate hepatic impairment (Child-Pugh score 5 to 9). There are no clinical or pharmacokinetic data in patients with severe hepatic impairment (Child -Pugh score greater than 9). Therefore, additional monitoring for adverse reactions in these patients may be warranted when Emend is administered [see Clinical Pharmacology (12.3)].

Is aprepitant present in rat milk?from drugs.com

Lactation studies have not been conducted to assess the presence of aprepitant in human milk, the effects on the breastfed infant, or the effects on milk production. Aprepitant is present in rat milk. The developmental and health benefits of breastfeeding should be considered along with the mother's clinical need for Emend and any potential adverse effects on the breastfed infant from Emend or from the underlying maternal condition.

How to contact prescription hope?

In the event your additional prescription medications are not currently on our list, contact our advocates at 1-877-296-HOPE (4673) today to see if it has been added.

How much does prescription hope cost?

Apply today, and start obtaining your prescription medications for the set price of $50.00 per month per medication .

Can I obtain other prescription medications through Prescription Hope?

In addition to Emend, Prescription Hope can obtain over 1,500 FDA-approved prescription medications. In fact, we help many Americans obtain multiple prescriptions for the set price of $50.00 per month per medication.

Can Prescription Hope help me with Emend if I have prescription medication coverage?

Because we are a national advocate and not a discount drug card or insurance plan, Prescription Hope can obtain pre scription medications without copays, deductibles, or medication tiers.

How long does it take for prescription hope to send medication?

After the application is approved, your first shipment of medication is typically sent within four to six weeks, with regular refills coming to either your home or doctor’s office.

What is emend used for?

Emend is a chemotherapy drug that is used to prevent nausea and vomiting caused by chemotherapy.

Why do you need emend?

Emend is used to prevent vomiting and nausea that is caused by chemotherapy or radiation therapy.

What is the Heron Connect Patient Assistance Program?

† This program is for patients with financial hardship who meet program eligibility criteria to receive CINVANTI at no cost.

What is the number to call Heron Therapeutics for CINVANTI?

Call Heron Connect for more information at 1-844-HERON11 (1-844-437-6611) ||

How to fax CINVANTI?

Complete the Insurance Verification and Program Enrollment Form. Fax this form and the prescription for CINVANTI to 1-844-504-8652.

How much is CINVANTI deductible?

When applicable, patients may also be eligible for deductible assistance up to $200 per treatment. You can enroll your patients in the following ways:

What is the MEC of a 3 day oral aprepitant?

3-day oral aprepitant with MEC (≥1% and greater than standard therapy): fatigue and eructation.

Can you drink CINVANTI while pregnant?

Avoid use of CINVANTI in pregnant women as alcohol is an inactive ingredient for CINVANTI. There is no safe level of alcohol exposure in pregnancy.

Does citantin reduce aprepitant plasma concentration?

Use of CINVANTI with strong CYP3A4 inducers (e.g., rifampin) may result in a reduction in aprepitant plasma concentrations and decreased efficacy of CINVANTI.

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Important Note

Uses

  • Aprepitant is used in combination with other drugs to help prevent nausea and vomiting due to cancer drug treatment (chemotherapy). This medication works by blocking one of the body's chemicals (substance P/neurokinin 1) that causes vomiting.
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How to Use

  • Take this medication by mouth, with or without food. The first dose is usually taken 1 hour before cancer chemotherapy treatment. On the following days, the dose is taken usually once daily in the morning; or use as directed by your doctor. It is important to follow your doctor's instructions for the timing of each dose and for the length of treatment. If you have any questions, consult your …
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Side Effects

  • Tiredness, weakness, nausea, constipation, diarrhea, loss of appetite, upset stomach, dizziness, headache and hiccups may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, severe diz…
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Precautions

  • Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe liver problems, any allergies. This drug may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages. This medication may decrease the effectiveness of combination-type birth control pills. You may nee…
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Drug Interactions

  • This drug should not be used with the following medications because very serious, potentially life-threatening, interactions may occur: astemizole, cisapride, pimozide, terfenadine. If you are currently using any of these medications, tell your doctor or pharmacist before starting aprepitant. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescripti…
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Missed Dose

  • It is important that each dose is taken according to the prescribed schedule. If you miss a dose, contact your doctor or pharmacist immediately to establish a new dosing schedule.
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Storage

  • Store at room temperature between 68 and 77 degrees F (20-25 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.
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