How to report side effects of Genentech?
Can tecentriq cause death?
Can you stop tecentriq?
Can tecentriq cause shortness of breath?
Does TecentrIQ cause fertility problems?
Is TECENTRIQ covered by insurance?
To be eligible for free TECENTRIQ from the Genentech Patient Foundation, insured patients who have coverage for their medicine must have exhausted all other forms of patient assistance (including the Genentech Oncology Co-pay Program and support from independent co-pay assistance foundations) and must meet certain ...
How long is Atezolizumab infusion?
Administer the initial infusion over 60 minutes through an intravenous line with or without a sterile, non-pyrogenic, low-protein binding in-line filter (pore size of 0.2–0.22 micron). If the first infusion is tolerated, all subsequent infusions may be delivered over 30 minutes.
How often is TECENTRIQ given?
How is TECENTRIQ given? Your healthcare provider will give you TECENTRIQ into your vein through an intravenous (IV) line. TECENTRIQ is given once every 3 weeks, as long as you continue to respond to and tolerate the treatment.
How long is TECENTRIQ infusion?
The first TECENTRIQ infusion is given over 60 minutes. If tolerated, the following infusions of TECENTRIQ may be given over 30 minutes. Additional time will be needed for your other medications.
Does atezolizumab cause hair loss?
Official answer. Hair loss (alopecia) has been reported as a common side effect with atezolizumab (brand name: Tecentriq) when used with other anticancer treatments in patients being treated for advanced lung cancer. Atezolizumab may also lead to hormone gland problems which can result in hair loss.
What cancers does atezolizumab treat?
Atezolizumab injection is used to treat urothelial carcinoma (a type of bladder cancer) that has spread throughout the body (metastatic) or cannot be removed by surgery (advanced).
How much is atezolizumab?
Official answer. Tecentriq treatment costs around $14,540 per month depending on the dosage schedule. Tecentriq (atezolizumab) is a programmed death-ligand 1 (PD-L1) blocking antibody (or immune checkpoint inhibitor) used in the treatment of: urothelial carcinoma.
Is TECENTRIQ hazardous?
Not a hazardous substance or mixture. None known.
Is TECENTRIQ effective?
The study showed that Tecentriq in combination with Avastin significantly reduced the risk of death (known as overall survival, a primary endpoint) by 42% (hazard ratio [HR]=0.58; 95% CI: 0.42-0.79; p=0.0006) compared to sorafenib (Nexavar).
What are the side effects of atezolizumab?
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What is atezolizumab made from?
*Atezolizumab is an Fc-engineered, humanised IgG1 anti-programmed death-ligand 1 (PD-L1) monoclonal antibody produced in Chinese hamster ovary cells by recombinant DNA technology.
Is TECENTRIQ chemo?
Tecentriq in combination with gemcitabine and one other chemotherapy drug that's made with platinum (either cisplatin or carboplatin)
What are the side effects of Atezolizumab?
AdvertisementBlack, tarry stools.bladder pain.chest tightness.difficulty in breathing.general feeling of tiredness and weakness.headache.muscle aches.nosebleed.More items...
Is Tecentriq a chemotherapy?
Tecentriq in combination with gemcitabine and one other chemotherapy drug that's made with platinum (either cisplatin or carboplatin)
What is the mechanism of action of Atezolizumab?
Mechanism of Action. Atezolizumab is a humanized monoclonal antibody immune checkpoint inhibitor that selectively binds to PD-L1 to stop the interaction between PD-1 and B7. 1 (ie, CD80 receptors). The antibody still allows interaction between PD-L2 and PD-1.
Is Tecentriq an immunotherapy?
The US Food and Drug Administration (FDA) has approved the immunotherapy drug Tecentriq (atezolizumab) for the treatment of small cell lung cancer (SCLC). It's the second immunotherapy drug approved for people with advanced SCLC, but the first approved for use as part of the initial (first-line) treatment.
Financial Assistance Options | TECENTRIQ Access Solutions
Genentech understands your medicine can be costly. TECENTRIQ Access Solutions can help you find financial assistance options for TECENTRIQ® (atezolizumab).
TECENTRIQ Access Solutions | Patients and Caregivers
TECENTRIQ Access Solutions is a program that helps patients taking TECENTRIQ® (atezolizumab). We can help you understand your health insurance coverage and find financial assistance options. Enroll online to get started.
Tecentriq: Uses, side effects, dosage, alternatives, and more
Tecentriq (atezolizumab) is a brand-name prescription drug that’s used to treat certain types of cancer. Learn about uses, side effects, dosage, and more.
How to monitor immune-mediated adverse reactions?
Monitor patients closely for symptoms and signs that may be clinical manifestations of underlying immune-mediated adverse reactions. Evaluate liver enzymes, creatinine, and thyroid function at baseline and periodically during treatment. In cases of suspected immune-mediated adverse reactions, initiate appropriate workup to exclude alternative etiologies, including infection. Institute medical management promptly, including specialty consultation as appropriate.
Can HSCT cause death?
Fatal and other serious complications can occur in patients who receive allogeneic hematopoietic stem cell transplantation (HSCT) before or after being treated with a PD-1/PD-L1 blocking antibody
Can tecentriq cause hypopituitarism?
TECENTRIQ can cause immune-mediated hypophysitis. Hypophysitis can present with acute symptoms associated with mass effect such as headache, photophobia, or visual field cuts. Hypophysitis can cause hypopituitarism. Initiate hormone replacement as clinically indicated
Can tecentriq cause pneumonitis?
TECENTRIQ can cause immune-mediated pneumonitis. The incidence of pneumonitis is higher in patients who have received prior thoracic radiation
Can you breastfeed with tecentriq?
Because of the potential for serious adverse reactions in breastfed infants from TECENTRIQ, advise female patients not to breastfeed while taking TECENTRIQ and for at least 5 months after the last dose.
Can tecentriq cause adrenal insufficiency?
TECENTRIQ can cause primary or secondary adrenal insufficiency. For Grade 2 or higher adrenal insufficiency, initiate symptomatic treatment, including hormone replacement as clinically indicated
Can a pregnant woman take tecentriq?
Based on its mechanism of action, TECENTRIQ can cause fetal harm when administered to a pregnant woman. There are no available data on the use of TECENTRIQ in pregnant women. Animal studies have demonstrated that inhibition of the PD-L1/PD-1 pathway can lead to increased risk of immune-related rejection of the developing fetus, resulting in fetal death
Coverage
Help understanding benefits and coverage, such as benefits investigations and prior authorization resources
Product Distribution
A list of authorized distributors and specialty pharmacies as well as information on our Spoilage Replacement Program
How to report side effects of Genentech?
You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at 1-888-835-2555. Please see full Prescribing Information and Medication Guide for additional Important Safety Information.
Can tecentriq cause death?
TECENTRIQ can cause your immune system to attack normal organs and tissues in any area of your body and can affect the way they work. These problems can sometimes become severe or life-threatening and can lead to death. You can have more than one of these problems at the same time.
Can you stop tecentriq?
Your healthcare provider may also need to delay or completely stop treatment with TECENTRIQ if you have severe side effects.
Can tecentriq cause shortness of breath?
Problems can also happen in other organs. These are not all of the signs and symptoms of immune system problems that can happen with TECENTRIQ. Call or see your healthcare provider right away for any new or worse signs or symptoms, including: Chest pain, irregular heartbeat, shortness of breath, or swelling of ankles.
Does TecentrIQ cause fertility problems?
TECENTRIQ may cause fertil ity problems in females, which may affect the ability to have children. Talk to your healthcare provider if you have concerns about fertility.
How to get patient consent form for Genentech?
Once we have both forms, we can begin working with you and your doctor's office. You can find the Patient Consent Form at Genentech-Access.com/PatientConsent or your doctor might give it to you.
What is a tecentriq access solution?
TECENTRIQ Access Solutions can refer you to the Genentech Oncology Co-pay Assistance Program. It can help you with the out-of-pocket costs of your Genentech medicine, if you’re eligible.*
Who gives free tecentriq?
The Genentech Patient Foundation gives free TECENTRIQ to people who don't have insurance coverage or who have financial concerns.
Who provides Genentech medicine?
The Genentech Patient Foundation provides free Genentech medicine to people who don't have insurance coverage or who have financial concerns and to people who meet certain income criteria.*
Does Genentech have copay assistance?
If you need help with the co-pay for your Genentech medicine, Genentech Oncology Access Solutions for TECENTRIQ can refer you to an independent co-pay assistance foundation. Independent co-pay assistance foundations help patients with public or commercial health insurance.
How to contact Genentech about compassionate use?from gene.com
If you are seeking information about access to one of Genentech's investigational medicines, please call Genentech's Clinical Trial Information Support Line at (888) 662-6728 or Genentech's Compassionate Use Information Line at (844) ...
Who gives Genentech medicine?from gene.com
The Genentech Patient Foundation gives free Genentech medicine to people who don’t have insurance coverage or who have financial concerns and meet eligibility criteria.
What is GSF patient library?from geneticsupportfoundation.org
GSF has a Patient Library that provides more background information on a variety of topics in genetics, including a genetics overview (Genetics 101), Genetics & Pregnancy, and Genetics & Cancer, among others. Learn more.
Can you get Genentech medicine if your health plan requires a step edit?from gene.com
This is called a “step edit.” If your health plan requires a step edit, you may not be eligible for free medicine from the Genentech Patient Foundation.
Can Genentech help with insurance?from gene.com
There are several programs that may be able to help you get your Genentech medicine. Genentech Access Solutions can help you understand your insurance coverage and can refer you to programs that may be able to help you pay for your medicine.
Can a prescriber and patient consent form be sent together?from gene.com
While it is preferred that the Prescriber Foundation Form and Patient Consent Form are sent together, we are still able to review the patient's eligibility if we receive them separately.
Do you need to complete a patient consent form?from gene.com
Both forms are required. No action can be taken until a completed Patient Consent Form and Prescriber Service Form have been received.
How to report side effects of Genentech?
You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at 1-888-835-2555. Please see full Prescribing Information and Medication Guide for additional Important Safety Information.
Can tecentriq cause death?
TECENTRIQ can cause your immune system to attack normal organs and tissues in any area of your body and can affect the way they work. These problems can sometimes become severe or life-threatening and can lead to death. You can have more than one of these problems at the same time.
Can you stop tecentriq?
Your healthcare provider may also need to delay or completely stop treatment with TECENTRIQ if you have severe side effects.
Can tecentriq cause shortness of breath?
Problems can also happen in other organs. These are not all of the signs and symptoms of immune system problems that can happen with TECENTRIQ. Call or see your healthcare provider right away for any new or worse signs or symptoms, including: Chest pain, irregular heartbeat, shortness of breath, or swelling of ankles.
Does TecentrIQ cause fertility problems?
TECENTRIQ may cause fertil ity problems in females, which may affect the ability to have children. Talk to your healthcare provider if you have concerns about fertility.
