What are patient assistance programs for Cardizem?
Patient Assistance Programs for Cardizem. Patient assistance programs (PAPs) are usually sponsored by pharmaceutical companies and provide free or discounted medicines to low income or uninsured and under-insured people who meet specific guidelines. Eligibility requirements vary for each program.
What is Cardizem used to treat?
Cardizem (diltiazem) is a member of the calcium channel blocking agents drug class and is commonly used for Angina Pectoris Prophylaxis and Heart Failure. Cardizem Prices The cost for Cardizem oral tablet 30 mg is around $678 for a supply of 100 tablets, depending on the pharmacy you visit.
Is there a generic version of Cardizem?
A generic version of Cardizem is available, see diltiazem prices. Cardizem (diltiazem) is a member of the calcium channel blocking agents drug class and is commonly used for Angina Pectoris Prophylaxis, and Heart Failure.
What happens when you increase the dose of Cardizem?
As the dose of CARDIZEM tablets is increased from a daily dose of 120 mg (30 mg qid) to 240 mg (60 mg qid) daily, there is an increase in area-under-the-curve of 2.3 times. When the dose is increased from 240 mg to 360 mg, daily, there is an increase in area-under-the-curve of 1.8 times. INDICATIONS AND USAGE
How long does it take for Cardizem to lower blood pressure?
Diltiazem starts to work on the day you start taking it, but for high blood pressure and angina it may take a couple of weeks to work fully. If you're taking diltiazem for high blood pressure, you may not have had any symptoms before.
How long does it take Cardizem to work for AFIB?
The oral immediate release diltiazem tablet has a fast onset of action of 30-60 minutes and is dosed every 6 hours. Intravenous continuous infusion diltiazem has a variable onset of action with a titration frequency of every 15-30 minutes.
What does Cardizem do for atrial fibrillation?
The calcium channel blockers diltiazem (Cardizem) and verapamil (Calan, Isoptin) are effective for initial ventricular rate control in patients with atrial fibrillation. These agents are given intravenously in bolus doses until the ventricular rate becomes slower.
What is diltiazem 300 mg used for?
Diltiazem is used alone or together with other medicines to treat angina (severe chest pain) or hypertension (high blood pressure). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly.
What should you avoid while taking diltiazem?
dilTIAZem food You may want to limit alcohol intake and avoid excessive consumption of grapefruit and grapefruit juice during treatment with dilTIAZem.
Will diltiazem convert AFIB?
Abstract. Prior studies have suggested that intravenous diltiazem reduces the probability of spontaneous conversion of atrial fibrillation (AF) to sinus rhythm in the electrophysiology laboratory and in patients with postoperative AF.
What is the first drug of choice for atrial fibrillation?
Amiodarone as a first-choice drug for restoring sinus rhythm in patients with atrial fibrillation: a randomized, controlled study.
Can you live in constant AFib?
With the right treatment and regular management, most people with persistent atrial fibrillation can live active, healthy lives. The longer persistent Afib goes without treatment, however, the harder it is to manage. It may become permanent or lead to severe complications such as blood clots or stroke.
Does Cardizem make you tired?
Yes. Though uncommon, diltiazem (Cardizem) can lower your heart rate. In some cases, it may make your heart rate too low, causing you to feel tired or weak. If this happens, you should seek medical attention.
What are the side effects of diltiazem 360 mg?
Dizziness, lightheadedness, weakness, nausea, flushing, constipation, and headache may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
How long does it take for diltiazem to lower heart rate?
The peak blood pressure-reducing and blood vessel-widening effects occur three to six hours after oral administration of diltiazem extended-release capsules, and at least 50% of the effect is still present after 24 hours. Immediate-release diltiazem tablets are usually taken three or four times a day.
What are the worst side effects of diltiazem?
The most serious side effects of diltiazem include:Slowed heart rate (bradycardia)Heart block (AV block)Heart rhythm problems (arrhythmias)Severe low blood pressure.Heart failure.Severe allergic reactions.
What is the drug of choice for atrial fibrillation?
Amiodarone as a first-choice drug for restoring sinus rhythm in patients with atrial fibrillation: a randomized, controlled study. Chest.
Is it better to take diltiazem in the morning or evening?
Because of the increased risk of myocardial ischemia in the morning hours, it has been suggested that the administration of anti-ischemic medication before bedtime may be more effective than the traditional morning dosing.
When should you not give Cardizem?
CARDIZEM is contraindicated in (1) patients with sick sinus syndrome except in the presence of a functioning ventricular pacemaker, (2) patients with second- or third-degree AV block except in the presence of a functioning ventricular pacemaker, (3) patients with hypotension (less than 90 mm Hg systolic), (4) patients ...
What should I monitor with diltiazem?
AssessmentMonitor BP and pulse prior to therapy, during dose titration, and periodically during therapy. ... Assess for rash periodically during therapy. ... Angina: Assess location, duration, intensity, and precipitating factors of patient's anginal pain.Arrhythmias: Monitor ECG continuously during administration.
What is Cardizem used for?
Cardizem (diltiazem) is a member of the calcium channel blocking agents drug class and is commonly used for Angina Pectoris Prophylaxis, and Heart Failure.
How much does a free drug card save?
The free Drugs.com Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions.
Is Cardizem a generic?
Prices are for cash paying customers only and are not valid with insurance plans. A generic version of Cardizem is available, see diltiazem prices. This Cardizem price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
Important Note
The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.
Uses
Diltiazem is a calcium channel blocker. Calcium is involved in blood vessel contraction. By blocking calcium, diltiazem relaxes and widens blood vessels. Diltiazem is used to treat chest pain (angina). Ask your doctor or pharmacist about possible problems related to use of short-acting calcium channel blockers.
How To Use
This medication should be swallowed whole with a full glass of water unless your doctor directs you otherwise. May be taken with or without meals. This drug must be taken as directed if used to prevent chest pain. It is not effective if taken only when chest pain occurs. Do not stop taking this medication suddenly without your doctor's permission.
Side Effects
This drug may cause dizziness and lightheadedness especially during the first few days. Avoid activities requiring alertness. When you sit or lie down for a while, get up slowly to allow your body to adjust and minimize dizziness.
Precautions
Before taking this drug, tell your doctor if you have: heart problems, liver disease, lung disease, allergies. Limit intake of alcohol while taking this drug. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. This drug is excreted into breast milk.
Drug Interactions
Tell your doctor of all prescription and nonprescription drugs you may use, especially of: cyclosporine, flecainide, beta-blockers (including eye drops), intravenous (IV) calcium, digoxin, lithium, disopyramide, high blood pressure medication, benzodiazepines (e.g., midazolam, triazolam), buspirone, lovastatin, quinidine, rifampin, carbamazepine, cimetidine, St John's wort.
Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include dizziness, weakness, slowed or irregular heartbeat, nausea, drowsiness, confusion, and slurred speech.
Important Note
The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.
Uses
Diltiazem is a calcium channel blocker. Calcium is involved in blood vessel contraction and in controlling the electrical impulses within the heart. By blocking calcium, diltiazem relaxes and widens blood vessels and can normalize heartbeats. Diltiazem is used to treat chest pain (angina) or high blood pressure.
How To Use
The capsule (s) may be taken without regard to meals once daily in the morning. Swallow whole. Do not open, chew or crush the capsule. Do not stop taking this drug suddenly without your doctor's permission. Your dose may need to be gradually decreased.
Side Effects
This drug may cause dizziness and lightheadedness especially during the first few days. Avoid activities requiring alertness. When you sit or lie down for a while, get up slowly to allow your body to adjust and minimize dizziness.
Precautions
Tell your doctor your medical history, especially: heart disease, liver disease, lung disease, any allergies. Limit intake of alcohol while taking this drug. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. This drug is excreted into breast milk.
Drug Interactions
Tell your doctor of all prescription and nonprescription drugs you may use, especially: cyclosporine, flecainide, beta-blockers (including eye drops), intravenous (IV) calcium, digoxin, lithium, disopyramide, high blood pressure medication, benzodiazepines (e.g., midazolam, triazolam), buspirone, lovastatin, quinidine, rifampin, carbamazepine, cimetidine, St John's wort.
Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include dizziness, weakness, slowed or irregular heartbeat, nausea, drowsiness, confusion, and slurred speech.
How is diltiazem absorbed?
Diltiazem is well absorbed from the gastrointestinal tract and is subject to an extensive first-pass effect, giving an absolute bioavailability (compared to intravenous dosing) of about 40%. CARDIZEM undergoes extensive metabolism in which 2% to 4% of the unchanged drug appears in the urine.In vitro binding studies show CARDIZEM is 70% to 80% bound to plasma proteins. Competitive in vitro ligand binding studies have also shown CARDIZEM binding is not altered by therapeutic concentrations of digoxin, hydrochlorothiazide, phenylbutazone, propranolol, salicylic acid, or warfarin. The plasma elimination half-life following single or multiple drug administration is approximately 3.0 to 4.5 hours. Desacetyl diltiazem is also present in the plasma at levels of 10% to 20% of the parent drug and is 25% to 50% as potent as a coronary vasodilator as diltiazem. Minimum therapeutic plasma levels of CARDIZEM appear to be in the range of 50 to 200 ng/mL. There is a departure from linearity when dose strengths are increased. A study that compared patients with normal hepatic function to patients with cirrhosis found an increase in half-life and a 69% increase in AUC (area-under-the-plasma concentration vs time curve) in the hepatically impaired patients. A single study in nine patients with severely impaired renal functions showed no difference in the pharmacokinetic profile of diltiazem as compared to patients with normal renal function.
Does diltiazem affect AH?
Like other calcium antagonists, diltiazem decreases sinoatrial and atrioventricular conduction in isolated tissues and has a negative inotropic effect in isolated preparations. In the intact animal, prolongation of the AH interval can be seen at higher doses.
Is diltiazem metabolized by the liver?
CARDIZEM (diltiazem hydrochloride) is extensively metabolized by the liver and excreted by the kidneys and in bile. As with any drug given over prolonged periods, laboratory parameters of renal and hepatic function should be monitored at regular intervals. The drug should be used with caution in patients with impaired renal or hepatic function. In subacute and chronic dog and rat studies designed to produce toxicity, high doses of diltiazem were associated with hepatic damage. In special subacute hepatic studies, oral doses of 125 mg/kg and higher in rats were associated with histological changes in the liver, which were reversible when the drug was discontinued. In dogs, doses of 20 mg/kg were also associated with hepatic changes; however, these changes were reversible with continued dosing. Dermatological events (see ADVERSE REACTIONS) may be transient and may disappear despite continued use of CARDIZEM. However, skin eruptions progressing to erythema multiforme and/or exfoliative dermatitis have also been infrequently reported. Should a dermatologic reaction persist, the drug should be discontinued.
How long after meal can you take Cardizem?
The extended-release capsule ( Cardizem SR ®, Dilacor XR ®, and Diltia XT ®) should be taken on an empty stomach, at least 1 hour before or 2 hours after a meal. The extended-release capsule ( Tiazac ®) may be taken with or without food. The dual-release capsule ( Cardizem CD ®) may be taken with food.
When was Cardizem LA approved?
In 2004, the U.S. Food and Drug Administration (FDA) approved Cardizem LA ® (ditiazem) for the treatment of chronic stable angina. Cardizem LA ® had also been earlier approved for the treatment of high blood pressure or hypertension and is a long acting extended-release formulation of diltiazem HCl. Why is this medication prescribed? ...
How does diltiazem work?
It works by relaxing (widening) your blood vessels (veins and arteries), which in turn makes it easier for your heart to pump and reduces the workload on it. Some of the brand names that diltiazem is marketed under include Cardizem®, Cartia XT®, Tiazac®, and Tiamate®. Brand Name (s): Cardizem; Cardizem CD; Cardizem SR; Cartia XT; Dilacor XR;
What is diltiazem used for?
WHAT IS Diltiazem? Diltiazem is used to treat several medical conditions, including hypertension (high blood pressure), angina (chest pain), and even to slow unusually fast heartbeats. Diltiazem is in a class of drugs called calcium channel blockers. It works by relaxing (widening) your blood vessels (veins and arteries), ...
Why is diltiazem prescribed?
Why is this medication prescribed? Diltiazem is used to treat hypertension (high blood pressure), angina (chest pain), and to slow unusually fast heartbeats. Diltiazem belongs to a class of medications called calcium channel blockers. These medications block the transport of calcium into the smooth muscle cells lining the coronary arteries ...
Does diltiazem help with chest pain?
By relaxing coronary arteries, diltiazem is useful in treating and preventing chest pain (angina) resulting from coronary artery spasm. The effect of relaxing the muscles lining the arteries of the rest of the body results in a lowering of blood pressure, which reduces the burden on the heart as it pumps blood to the body.
Does diltiazem relax arteries?
By relaxing coronary arteries, diltiazem is ...
How to use diltiazem?
HOW TO USE: Take this medication by mouth with or without food, usually once daily or as directed by your doctor. Swallow the capsules whole. Do not crush or chew the capsules.
How to report diltiazem side effects?
You may report side effects to Health Canada at 1-866-234-2345. PRECAUTIONS: Before taking diltiazem, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
What medications can affect the removal of diltiazem?
Examples include atazanavir, cimetidine, quinidine, St. John's wort, azole antifungals such as ketoconazole, macrolide antibiotics such as erythromycin, rifamycins including rifabutin and rifampin.
How to treat angina attack?
Use other medications (such as nitroglycerin placed under the tongue) to relieve an angina attack as directed by your doctor. Consult your doctor or pharmacist for details. Tell your doctor if your condition worsens (for example, your chest pain worsens or your routine blood pressure readings increase).
How long does it take to get the full benefit of a blood pressure medicine?
Most people with high blood pressure do not feel sick. For the treatment of high blood pressure, it may take 2 to 4 weeks before you get the full benefit of this drug.
How to contact Healthwarehouse?
Phone: 1-800-748-7001. Email: [email protected]. We need just a little extra information. As a VIPPS accredited pharmacy licensed and/or authorized in all 50 states, pharmacy regulation requires us to ask for your shipping zip code. Product ID: *DILTIAZEMER360.
Does diltiazem lower heart rate?
Diltiazem also lowers your heart rate . These effects help the heart work less hard and lower blood pressure. OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional.
How is diltiazem absorbed?
Diltiazem is well absorbed from the gastrointestinal tract and is subject to an extensive first-pass effect, giving an absolute bioavailability (compared to intravenous administration) of about 40%. CARDIZEM undergoes extensive metabolism in which only 2% to 4% of the unchanged drug appears in the urine.
What is diltiazem in animal models?
In animal models, diltiazem interferes with the slow inward (depolarizing) current in excitable tissue. It causes excitation-contraction uncoupling in various myocardial tissues without changes in the configuration of the action potential.
What were the events that occurred after diltiazem overdose?
Events observed following diltiazem overdose included bradycardia, hypotension, heart block, and cardiac failure. Most reports of overdose described some supportive medical measure and/or drug treatment. Bradycardia frequently responded favorably to atropine, as did heart block, although cardiac pacing was also frequently utilized to treat heart block. Fluids and vasopressors were used to maintain blood pressure and in cases of cardiac failure, inotropic agents were administered. In addition, some patients received treatment with ventilatory support, gastric lavage, activated charcoal, and/or intravenous calcium.
What is the chemical structure of diltiazem?
The chemical structure is: Diltiazem hydrochloride is a white to off-white crystalline powder with a bitter taste. It is soluble in water, methanol, and chloroform. It has a molecular weight of 450.98. CARDIZEM CD is formulated as a once-a-day extended-release capsule containing 120 mg, 180 mg, 240 mg, 300 mg, or 360 mg diltiazem hydrochloride.
How much diltiazem can you overdose on?
There have been reports of diltiazem overdose in amounts ranging from <1 g to 18 g. Of cases with known outcome, most patients recovered and in cases with a fatal outcome, the majority involved multiple drug ingestion.
How much titration for angina?
Angina. Dosages for the treatment of angina should be adjusted to each patient's needs, starting with a dose of 120 or 180 mg once daily. Individual patients may respond to higher doses of up to 480 mg once daily. When necessary, titration may be carried out over a 7- to 14-day period.
Does diltiazem affect contractility?
Although diltiazem has a negative inotropic effect in isolated animal tissue preparations, hemodynamic studies in humans with normal ventricular function have not shown a reduction in cardiac index nor consistent negative effects on contractility (dp/dt). An acute study of oral diltiazem in patients with impaired ventricular function (ejection fraction 24%± 6%) showed improvement in indices of ventricular function without significant decrease in contractile function (dp/dt). Worsening of congestive heart failure has been reported in patients with preexisting impairment of ventricular function. Experience with the use of CARDIZEM (diltiazem hydrochloride) in combination with beta-blockers in patients with impaired ventricular function is limited. Caution should be exercised when using this combination.
Important Note
- The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug. DILTIAZEM TABLET - ORAL (dill-TIE-uh-zem) CO…
Uses
- Diltiazem is a calcium channel blocker. Calcium is involved in blood vessel contraction. By blocking calcium, diltiazem relaxes and widens blood vessels. Diltiazem is used to treat chest pain (angina). Ask your doctor or pharmacist about possible problems related to use of short-acting calcium channel blockers.
How to Use
- This medication should be swallowed whole with a full glass of water unless your doctor directs you otherwise. May be taken with or without meals. This drug must be taken as directed if used to prevent chest pain. It is not effective if taken only when chest pain occurs. Do not stop taking this medication suddenly without your doctor's permission. ...
Side Effects
- This drug may cause dizziness and lightheadedness especially during the first few days. Avoid activities requiring alertness. When you sit or lie down for a while, get up slowly to allow your body to adjust and minimize dizziness. You may also experience bloating, heartburn, muscle cramps, headache, flushing, nasal congestion, sore throat, constipation or diarrhea. Inform your doctor if …
Precautions
- Before taking this drug, tell your doctor if you have: heart problems, liver disease, lung disease, allergies. Limit intake of alcohol while taking this drug. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. This drug is excreted into breast milk. If there is no alternative to using this drug you should discontinue brea…
Drug Interactions
- Tell your doctor of all prescription and nonprescription drugs you may use, especially of: cyclosporine, flecainide, beta-blockers (including eye drops), intravenous (IV) calcium, digoxin, lithium, disopyramide, high blood pressure medication, benzodiazepines (e.g., midazolam, triazolam), buspirone, lovastatin, quinidine, rifampin, carbamazepine, cimetidine, St John's wort. …
Overdose
- If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include dizziness, weakness, slowed or irregular heartbeat, nausea, drowsiness, confusion, and slurred speech.
Missed Dose
- If you miss a dose, take as soon as remembered; do not take if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.
Medical Alert
- Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).
Important Note
- The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug. DILTIAZEM 24 HOUR SUSTAINED ACTION CAPS…
Uses
- Diltiazem is a calcium channel blocker. Calcium is involved in blood vessel contraction and in controlling the electrical impulses within the heart. By blocking calcium, diltiazem relaxes and widens blood vessels and can normalize heartbeats. Diltiazem is used to treat chest pain (angina) or high blood pressure. OTHER
How to Use
- The capsule(s) may be taken without regard to meals once daily in the morning. Swallow whole. Do not open, chew or crush the capsule. Do not stop taking this drug suddenly without your doctor's permission. Your dose may need to be gradually decreased.
Side Effects
- This drug may cause dizziness and lightheadedness especially during the first few days. Avoid activities requiring alertness. When you sit or lie down for a while, get up slowly to allow your body to adjust and minimize dizziness. You may also experience bloating, heartburn, muscle cramps, headache, flushing, nasal congestion, sore throat, constipa...
Precautions
- Tell your doctor your medical history, especially: heart disease, liver disease, lung disease, any allergies. Limit intake of alcohol while taking this drug. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. This drug is excreted into breast milk. If there is no alternative to using this drug you should discontinue brea…
Drug Interactions
- Tell your doctor of all prescription and nonprescription drugs you may use, especially: cyclosporine, flecainide, beta-blockers (including eye drops), intravenous (IV) calcium, digoxin, lithium, disopyramide, high blood pressure medication, benzodiazepines (e.g., midazolam, triazolam), buspirone, lovastatin, quinidine, rifampin, carbamazepine, cimetidine, St John's wort. …
Overdose
- If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include dizziness, weakness, slowed or irregular heartbeat, nausea, drowsiness, confusion, and slurred speech.
Missed Dose
- If you miss a dose, take as soon as remembered; do not take if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.
Medical Alert
- Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).