Does Pomalyst cause liver damage?
Pomalidomide, like the structurally related agents thalidomide and lenalidomide, is associated with a low rate of serum aminotransferase elevations during therapy and has been implicated in causing rare instances of clinically apparent liver injury which can be severe.
What does it mean when Pomalidomide is prescribed multiple myeloma?
This medicine is used in patients with multiple myeloma that has worsened during treatment or within 60 days of the last treatment. It interferes with the growth of multiple myeloma cells, which are eventually destroyed in the body. Pomalidomide is an antineoplastic (cancer medicine).
What drug company makes Pomalyst?
Pomalyst is manufactured by Celgene. The Multiple Myeloma Research Consortium (MMRC) played an integral role in the development of Pomalyst, partnering with Celgene in the early clinical trials that established its efficacy, and continues to sponsor trials evaluating Pomalyst in combination with other myeloma drugs.
Where do you put medicine in your home?
Store your medicines in a cool, dry place. For example, store it in your dresser drawer or a kitchen cabinet away from the stove, sink, and any hot appliances. You can also store medicine in a storage box, on a shelf, or in a closet.
How long can you take Pomalyst?
Dosage for Kaposi sarcoma The usual dose of Pomalyst to treat Kaposi sarcoma (KS) is 5 mg once a day. You'll likely take this dose on days 1 through 21 of your 28 day treatment cycle. Your doctor may have you stop taking Pomalyst if your KS gets worse or if side effects become too bothersome.
What time of day is best to take Pomalyst?
Take Pomalyst only as directed (once daily) at the same time each day. Take this medication without food (at least two hours before or two hours after a meal) and do not open, break, or chew capsules. Swallow capsules whole with water.
What does POMALYST cost?
The cost for Pomalyst oral capsule 1 mg is around $20,983 for a supply of 21 capsules, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans. This Pomalyst price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
How effective is POMALYST?
Overall survival was 10.9 months for all refractory patients. There was a response rate of 34% for those refractory to Revlimid and 33% for those refractory to both Revlimid and Velcade.
Can you drink alcohol with POMALYST?
Do not combine this medication with other medications that can cause dizziness and confusion. Do not drink alcohol while taking this medication.
Why Should medicines not be thrown away in a sink or toilet?
These pharmaceuticals can pollute our water and unintentionally expose us to the chemicals in these medications. Recent studies have found that medicines flushed down the drain can contaminate our lakes and streams, which can hurt fish and other aquatic wildlife, and end up in our drinking water.
What drugs have to be kept cold?
MEDICATIONS THAT REQUIRE COLD CHAIN SHIPPING SOLUTIONSInsulin.Victoza.Botox.Humira.Byetta.All vaccines.Caverject.
Can we keep medicines in bedroom?
Never keep medicines on the side table in the bedroom. If keeping any kind of medicine near the bed is important at night, remove it in the morning. The medicines should always be kept in the Northern direction. Do not keep a refrigerator, invertor, gas cylinder or a dustbin in your bedroom.
Is pomalidomide a chemotherapy?
Pomalidomide is the generic name for the trade name chemotherapy drug Pomalyst®. In some cases, health care professionals may use the trade name Pomalyst® when referring to the generic drug pomalidomide.
What is the difference between Revlimid and Pomalyst?
POMALYST has immune-modulating qualities similar to REVLIMID® (lenalidomide). However, POMALYST with dexamethasone is proven to continue the fight if multiple myeloma stops responding to REVLIMID and a proteasome inhibitor.
What is the mechanism of action of pomalidomide?
Mechanism of action Pomalidomide directly inhibits angiogenesis and myeloma cell growth. This dual effect is central to its activity in myeloma, rather than other pathways such as TNF alpha inhibition, since potent TNF inhibitors including rolipram and pentoxifylline do not inhibit myeloma cell growth or angiogenesis.
How is pomalidomide administered?
Pomalidomide should be administered on an empty stomach (at least 2 hours before or 2 hours after a meal). Missed doses may be administered if within 12 hours of the usual dosing time of pomalidomide.
How to contact POMALYST?
Your experience could help inspire fellow patients, caregivers, and healthcare professionals. To contact us, call 1‑800‑657‑9801 or email [email protected].
How old do you have to be to sign up for Celgene?
Must be 18 years of age or older to sign up. Please see Privacy Policy to learn more about Celgene’s use of submitted information.
What do you need to know before taking pomalyst?
Before you begin taking POMALYST, you must read and agree to all of the instructions in the POMALYST REMS ® program. Before prescribing POMALYST, your healthcare provider (HCP) will explain the POMALYST REMS program to you and have you sign the Patient-Physician Agreement Form.
What is my momentum program?
VO: The My Momentum program provides support that may help you with your multiple myeloma journey.
Does POMALYST help with blood clots?
Most people who take POMALYST will also take a blood thinner medicine to help prevent blood clots.
Can you donate blood while taking pomalyst?
Do not donate blood while you take POMALYST, during any breaks (interruptions) in your treatment, and for 4 weeks after stopping POMALYST. If someone who is pregnant gets your donated blood, her baby may be exposed to POMALYST and may be born with birth defects.
Can you use condoms while taking pomalyst?
Males, including those who have had a vasectomy, must always use a latex or synthetic condom during any sexual contact with a pregnant female or a female that can become pregnant while taking POMALYST, during any breaks (interruptions) in your treatment with POMALYST, and for 4 weeks after stopping POMALYST.
Pomalyst Prices
The cost for Pomalyst oral capsule 1 mg is around $20,803 for a supply of 21 capsules, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
Drugs.com Printable Discount Card
The free Drugs.com Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions.
Pomalyst Coupons and Rebates
Pomalyst offers may be in the form of a printable coupon, rebate, savings card, trial offer, or free samples. Some offers may be printed right from a website, others require registration, completing a questionnaire, or obtaining a sample from the doctor's office.
Patient Assistance Programs for Pomalyst
Patient assistance programs (PAPs) are usually sponsored by pharmaceutical companies and provide free or discounted medicines to low income or uninsured and under-insured people who meet specific guidelines. Eligibility requirements vary for each program.
What is the goal of the POMALYST risk evaluation and mitigation strategy?
The goals of the POMALYST risk evaluation and mitigation strategy are as follows: To prevent the risk of embryo-fetal exposure to POMALYST. To inform prescribers, patients, and pharmacists on the serious risks and safe-use conditions.
What is pomalidomide?
Important information about POMALYST ® (pomalidomide) and the POMALYST Risk Evaluation and Mitigation Strategy (REMS) program 1 POMALYST is contraindicated in pregnant females and females capable of becoming pregnant. Females of reproductive potential may be treated with POMALYST provided adequate precautions are taken to avoid pregnancy 2 To avoid embryo-fetal exposure, POMALYST is only available under a restricted distribution program called " POMALYST REMS® " 3 Only prescribers and pharmacies certified by the POMALYST REMS® program can prescribe and dispense POMALYST to patients who are enrolled and meet all the conditions of the POMALYST REMS® program
Is POMALYST available under a restricted distribution program?
To avoid embryo-fetal exposure, POMALYST is only available under a restricted distribution program called " POMALYST REMS® ". Only prescribers and pharmacies certified by the POMALYST REMS® program can prescribe and dispense POMALYST to patients who are enrolled and meet all the conditions of the POMALYST REMS® program.
What is the most common adverse reaction to POMALYST?
Hematologic Toxicity: Neutropenia (46%) was the most frequently reported Grade 3 or 4 adverse reaction in patients taking POMALYST in clinical trials, followed by anemia and thrombocytopenia. Monitor complete blood counts weekly for the first 8 weeks and monthly thereafter. Patients may require dose interruption and/or modification.
What is the grade of confusional state in POMALYST?
Dizziness and Confusional State: In patients taking POMALYST in clinical trials, 14% experienced dizziness (1% Grade 3 or 4) and 7% a confusional state (3% Grade 3 or 4). Instruct patients to avoid situations where dizziness or confusional state may be a problem and not to take other medications that may cause dizziness or confusional state without adequate medical advice.
What is the treatment for multiple myeloma?
POMALYST + dexamethasone + is atuximab-irfc is indicated for the treatment of adult patients with multiple myeloma who have received at least two prior therapies including lenalidomide and a proteasome inhibitor.
How to monitor neutropenia?
Neutropenia: Monitor complete blood cell counts periodically during treatment. Monitor patients with neutropenia for signs of infection. Consider withholding daratumumab and hyaluronidase-fihj to allow recovery of neutrophils.
What is a DVT in POMALYST?
Deep venous thrombosis (DVT), pulmonary embolism (PE), myocardial infarction, and stroke occur in patients with multiple myeloma treated with POMALYST. Prophylactic antithrombotic measures were employed in clinical trials. Thromboprophylaxis is recommended, and the choice of regimen should be based on assessment of the patient’s underlying risk factors.
Can you donate blood during a period of POMALYST?
Blood Donation: Patients must not donate blood during treatment with POMALYST and for 4 weeks following discontinuation of POMALYST therapy because the blood might be given to a pregnant female patient whose fetus must not be exposed to POMALYST.
Can a pregnant woman take a POMALYST?
Pregnancy: POMALYST can cause fetal harm and is contraindicated in females who are pregnant. If the patient becomes pregnant while taking this drug, the patient should be apprised of the potential risk to a fetus.
What is BMS Access Support?
BMS Access Support ® can help identify financial assistance programs for eligible patients who have been prescribed POMALYST and who need help managing the cost of treatment. The appropriate program will depend on the patient’s coverage.
Does Bristol Myers Squibb guarantee reimbursement?
Bristol Myers Squibb cannot guarantee that a patient will receive assistance. The accurate completion of reimbursement- or coverage-related documentation is the responsibility of the healthcare provider and patient. Bristol Myers Squibb and its agents make no guarantee regarding reimbursement for any service or item.
Does Bristol Myers Squibb provide free medical care?
The Bristol Myers Squibb Patient Assistance Foundation (BMSPAF), a charitable organization, may also provide medicine, free of charge, to eligible, uninsured patients who have an established financial hardship. For more information and eligibility criteria, visit bmspaf.org.
