Full Answer
What tier drug is Revlimid?
What drug tier is Revlimid typically on? Medicare prescription drug plans typically list Revlimid on Tier 5 of their formulary. Generally, the higher the tier, the more you have to pay for the medication.
What is the monthly cost of Revlimid?
Celgene launched Revlimid in 2005 at a price of $215 per pill. After more than 20 price hikes, the drug now costs $763 per pill, or $16,023 per month.
How long can you take Revlimid?
You won't take the drug on days 22 to 28. Revlimid can be taken for up to 12 cycles. Your doctor will likely prescribe Revlimid with the medication rituximab (Truxima, Rituxan).
How do you get Revlimid?
REVLIMID is only available through a select network of specialty pharmacies due to a restricted distribution program called Lenalidomide REMS. These specialty pharmacies help to manage the handling and shipping of REVLIMID and may provide additional resources.
Is Revlimid a chemotherapy?
Revlimid | Chemotherapy Drug Information | Chemocare.com.
What is the life expectancy for multiple myeloma Stage 3?
Life Expectancy With Stage III Multiple Myeloma This is called the 5-year relative survival rate. Current research puts the 5-year survival rate for stage III multiple myeloma at about 53%. However, there are various factors other than stage that can influence your chance of survival.
What are the long term effects of taking Revlimid?
It's possible that Revlimid can cause long-term side effects. For example, this medication may cause: liver problems, such as liver failure. other types of cancer, such as skin cancer or leukemia.
What is the success rate of Revlimid?
Patients who took REVLIMID and dexamethasone continuously had a 75% response rate compared to 73% of patients who took REVLIMID and dexamethasone for only 18 months and 62% of patients who took the combination of melphalan, prednisone, and thalidomide.
How Long Can multiple myeloma stay in remission?
The period of time between relapses varies from person to person. But for many, the first remission can last 2 years or more.
Is there a generic brand of REVLIMID?
Generic Versions of Revlimid and Velcade Now Available for Patients With Multiple Myeloma. In the first half of 2022, the Food and Drug Administration (FDA) approved generic versions of the two drugs most commonly used as the backbone of multiple myeloma combination therapies, Revlimid and Velcade.
What is the generic name for REVLIMID?
Generic Name: lenalidomide. Lenalidomide is used to treat various types of cancers. It works by slowing or stopping the growth of cancer cells. It is also used to treat anemia in patients with certain blood/bone marrow disorders (myelodysplastic syndromes-MDS).
How much is REVLIMID Canada?
In Canada, Revlimid costs between $8,000 and $10,000 Canadian per month, depending on dosage.
Is there a generic for Revlimid?
Generic Versions of Revlimid and Velcade Now Available for Patients With Multiple Myeloma. In the first half of 2022, the Food and Drug Administration (FDA) approved generic versions of the two drugs most commonly used as the backbone of multiple myeloma combination therapies, Revlimid and Velcade.
How long is maintenance treatment for multiple myeloma?
There is some debate about the optimal length of maintenance therapy in today's myeloma world. Most European doctors will have a fixed duration (2-3 years) of maintenance therapy but that could be related to approvals by European regulatory agencies. Most US doctors suggest "until disease progression".
Does Medicare cover multiple myeloma?
"As most patients with myeloma in the United States are covered by Medicare, our results have important implications both for the clinicians who care for these patients and for health-care policy that tackles coverage of oral and parenteral anticancer therapy."
What is the generic name for Revlimid?
Generic Name: lenalidomide. Lenalidomide is used to treat various types of cancers. It works by slowing or stopping the growth of cancer cells. It is also used to treat anemia in patients with certain blood/bone marrow disorders (myelodysplastic syndromes-MDS).
Who is the FDA contact for Revlimid?
FDA MedWatch at 1-800-FDA-1088. Celgene Corporation, a Bristol Myers Squibb company, at 1-888-423-5436. There is a pregnancy exposure registry that monitors the outcomes of females who take REVLIMID during pregnancy, or if their male partner takes REVLIMID and they are exposed during pregnancy.
What does a specialty pharmacy do with Revlimid?
The specialty pharmacy will contact you to provide counseling on the serious risks and safe-use conditions of REVLIMID before you receive your prescription. They will also coordinate delivery of REVLIMID to you
What do you need to know before prescribing Revlimid?
Before you begin taking REVLIMID, you must read and agree to all of the instructions in the REVLIMID REMS program. Before prescribing REVLIMID, your healthcare provider will explain the REVLIMID REMS program to you and have you sign the Patient-Physician Agreement Form.
How long do you have to take a second pregnancy test before you can get a prescription for Revlimid?
If you can get pregnant, you must take a second pregnancy test within 24 hours before getting a REVLIMID prescription
What to do if you are pregnant while taking Revlimid?
If you become pregnant while taking REVLIMID, stop taking it right away and call your healthcare provider. If your healthcare provider is not available, you can call 1-888-423-5436 for medical information. Healthcare providers and patients should report all cases of pregnancy to:
Can you give Revlimid to a partner?
Your healthcare provider will counsel you on why and how you and your partner should prevent pregnancy. Your healthcare provider will also inform you not to share the drug, not to donate blood or sperm, and about appropriate contraceptive use. You should be instructed not to extensively handle or open REVLIMID ® (lenalidomide) capsules
Can Revlimid be used for CLL?
REVLIMID should not be used to treat people who have chronic lymphocytic leukemia (CLL) unless they are participants in a controlled clinical trial. It is not known if REVLIMID is safe and effective in children.
Patients With Commercial (Private) Insurance
The BMS Oncology Co-Pay Assistance Program helps commercially insured patients who have been prescribed select BMS medications with out-of-pocket deductibles, co-pays, or co-insurance requirements. Eligible patients may pay as little as $10 per one-month supply, up to a maximum of $15,000 per calendar year.
Patients With Insurance Through Federal Healthcare Programs
Patients insured through Federal Healthcare Programs are not eligible for co-pay assistance programs sponsored by Bristol Myers Squibb.
Patients Without Prescription Drug Coverage or Who Are Underinsured
For patients without prescription drug insurance or for patients who are underinsured, BMS Access Support can make a referral to independent charitable foundations that may be able to help.
What is Celgene patient support?
Celgene Patient Support® is here to help you and your loved ones understand the financial help that may be available for REVLIMID®.
How to contact Celgene insurance?
Call your Specialist at 1-800-931-8691. If you have commercial insurance, you may qualify for the Celgene Commercial Co-pay Program. If you qualify, your out-of-pocket co-pay responsibility will be $25(subject to annual benefit limit) for REVLIMID.
Is Revlimid a trademark?
Celgene Patient Support®and REVLIMID are registered trademarks of Celgene Corporation. Other trademarks are the property of their respective owners. © 2019 Celgene Corporation 09/19 US-REV-19-0425
What is Celgene's commitment to patients?
Underlying Celgene’s commitment to improve the lives of patients worldwide is our dedication to change the course of human health through bold pursuits in science and a promise to always put patients first. At Celgene, we believe that a commitment to medical progress must go hand-in-hand with a corresponding mission to help ensure that patients who can benefit from our discoveries have the opportunity to do so.
What is Celgene's mission?
Celgene realizes its mission of improving the lives of patients around the world through our pioneering patient access programs, significant investment in clinical studies, support for continuing medical education and partnerships with charities that share our commitment to patients.#N#Learn More
Warnings and Precautions
- Embryo-Fetal Toxicity: See Boxed WARNINGS. 1. Females of Reproductive Potential: See Boxed WARNINGS. 2. Males: Lenalidomide is present in the semen of patients receiving the drug. Males must always use a latex or synthetic condom during any sexual contact with females of reprodu…
Multiple Myeloma
- In newly diagnosed: The most frequently reported Grade 3 or 4 reactions included neutropenia, anemia, thrombocytopenia, pneumonia, asthenia, fatigue, back pain, hypokalemia, rash, cataract, lymphop...
- The most common adverse reactions reported in ≥20% (Arm Rd Continuous): diarrhea (45%), anemia (44%), neutropenia (35%), fatigue (33%), back pain (32%), asthenia (28%), insomnia (2…
- In newly diagnosed: The most frequently reported Grade 3 or 4 reactions included neutropenia, anemia, thrombocytopenia, pneumonia, asthenia, fatigue, back pain, hypokalemia, rash, cataract, lymphop...
- The most common adverse reactions reported in ≥20% (Arm Rd Continuous): diarrhea (45%), anemia (44%), neutropenia (35%), fatigue (33%), back pain (32%), asthenia (28%), insomnia (28%), rash (26%),...
- Maintenance Therapy Post Auto-HSCT:The most frequently reported Grade 3 or 4 reactions in ≥20% (REVLIMID arm) included neutropenia, thrombocytopenia, and leukopenia. The serious adverse reactions o...
- The most frequently reported adverse reactions in ≥20% (REVLIMID arm) across both mainte…
Drug Interactions
- Periodically monitor digoxin plasma levels due to increased Cmaxand AUC with concomitant REVLIMID therapy. Patients taking concomitant therapies such as ESAs or estrogen-containing therapies may have an increased risk of thrombosis. It is not known whether there is an interaction between dexamethasone and warfarin. Close monitoring of PT and INR is recommen…
Use in Specific Populations
- PREGNANCY: See Boxed WARNINGS:If pregnancy does occur during treatment, immediately discontinue the drug and refer patient to an obstetrician/gynecologist experienced in reproductive toxicity for f...
- LACTATION: There is no information regarding the presence of lenalidomide in human milk, the effects of REVLIMID on the breastfed infant, or the effects of REVLIMID on milk productio…
- PREGNANCY: See Boxed WARNINGS:If pregnancy does occur during treatment, immediately discontinue the drug and refer patient to an obstetrician/gynecologist experienced in reproductive toxicity for f...
- LACTATION: There is no information regarding the presence of lenalidomide in human milk, the effects of REVLIMID on the breastfed infant, or the effects of REVLIMID on milk production. Because many...
- RENAL IMPAIRMENT: Adjust the starting dose of REVLIMID based on creatinine clearance value and for patients on dialysis.