Thank you for your interest in the Bristol-Myers Squibb Patient Assistance Foundation (BMSPAF) ERBITUX® (Cetuximab) Patient Assistance Program. This program is designed to provide assistance based on financial need and the absence of insurance coverage to patients who are currently receiving or planning to receive ERBITUX therapy. To be eligible, patients must not have outpatient prescription drug assistance through Medicaid, Medicare, or any other public or private health care or insurance program, and must not be appealing any denial of insurance coverage for ERBITUX therapy. Attached is an application for the program.
Full Answer
Does Eli Lilly have a patient assistance program?
Lilly Cares® Foundation Patient Assistance Program Helping patients with financial need receive their prescribed Eli Lilly and Company (Lilly) medications at no cost.
What are the side effects of cetuximab?
The most common side effects of Erbitux include:rash,itching,dry or cracked skin,nail changes,headache,diarrhea,nausea,vomiting,More items...
Who manufactures Erbitux?
Erbitux is a trademark owned by or licensed to Eli Lilly and Company , its subsidiaries, or affiliates.
Is Erbitux chemo?
ERBITUX with platinum-based chemotherapy and fluorouracil (CT) was shown to help some people live longer compared to CT alone. Half the patients on ERBITUX with CT were still alive at 10.1 months, compared to 7.4 months with CT alone (median overall survival).
How successful is cetuximab?
Cetuximab also has activity as monotherapy in patients with recurrent and/or metastatic SCCHN who had failed platinum-based chemotherapy,. with a 12.6% response rate, disease control rate of 46%, and median response duration of ~ 6 months.
How do you know if cetuximab is working?
Treatment with cetuximab may cause changes in the way your liver works. This will return to normal when the treatment finishes. You're very unlikely to notice any problems, but your doctor or nurse will take regular blood samples to check your liver is working properly. You will have regular blood tests to check this.
What is the cost of cetuximab?
The Costs of Cancer TreatmentsDrug (brand name)RegimenTotal cost ‡Cetuximab (Erbitux)Loading: 400 mg/m 2 ; maintain: 250 mg/m 2 /wk$80 352Bevacizumab (Avastin)10 mg/kg every 14 d$90 816Erlotinib (Tarceva)150 mg daily$15752Sorafenib (Nexavar)400 mg twice a day$34373
How long does cetuximab take to work?
It takes about 2 hours the first time you have it. If you don't have any problems, the following treatments take an hour. How long you have cetuximab depends on your cancer type. You have cetuximab on its own or with other chemotherapy drugs.
What does cetuximab rash look like?
Patients may develop a rash. While this rash may look like acne, it is not, and should not be treated with acne medications. The rash may appear red, swollen, crusty and dry, and feel sore. You may also develop very dry skin, which may crack, be itchy or become flaky or scaly.
Can cetuximab shrink Tumours?
In this study, the side effects and severity of adverse reactions seen with the cetuximab product used were consistent with other studies of US patients receiving ERBITUX for mCRC. Shrinkage of combined tumor size was ≥50%.
How long is ERBITUX treatment?
The data described in Warnings and Precautions reflect exposure to ERBITUX in 1373 patients with SCCHN or CRC enrolled in clinical trials and treated at the recommended dosage for a median of 7 to 14 weeks [see Clinical Studies].
How long does ERBITUX stay in your system?
Erbitux can have long-lasting effects on your body. You may need medical tests for at least 8 weeks after your last dose.
How long does cetuximab take to work?
It takes about 2 hours the first time you have it. If you don't have any problems, the following treatments take an hour. How long you have cetuximab depends on your cancer type. You have cetuximab on its own or with other chemotherapy drugs.
Is cetuximab immunotherapy or chemotherapy?
Immunotherapy with monoclonal antibodies, such as avelumab and cetuximab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.
What does cetuximab rash look like?
Patients may develop a rash. While this rash may look like acne, it is not, and should not be treated with acne medications. The rash may appear red, swollen, crusty and dry, and feel sore. You may also develop very dry skin, which may crack, be itchy or become flaky or scaly.
What is the cost of cetuximab?
The Costs of Cancer TreatmentsDrug (brand name)RegimenTotal cost ‡Cetuximab (Erbitux)Loading: 400 mg/m 2 ; maintain: 250 mg/m 2 /wk$80 352Bevacizumab (Avastin)10 mg/kg every 14 d$90 816Erlotinib (Tarceva)150 mg daily$15752Sorafenib (Nexavar)400 mg twice a day$34373
What are the adverse reactions to cetuximab?
The most common adverse reactions (all grades; incidence ≥25%) seen in patients with carcinomas of the head and neck receiving a cetuximab product in combination with platinum-based therapy and fluorouracil (CT) (n=219) versus CT alone (n=215) (EXTREM E) were acneiform rash (70% vs 2%), nausea (54% vs 47%) , infection (44% vs 27%) , rash (28% vs 2%), diarrhea (26% vs 16%) and anorexia ( 25% vs 14%). The most common grade 3 and 4 adverse reaction for a cetuximab product in combination with CT (≥10%) versus CT alone was infection (11% vs 8%). Because ERBITUX provides approximately 22% higher exposure relative to the cetuximab product used in EXTREME, the data provided above may underestimate the incidence and severity of adverse reactions anticipated with ERBITUX for this indication. However, the tolerability of the recommended dose is supported by safety data from additional studies of ERBITUX.
What is ERBITUX used for?
ERBITUX is indicated for the treatment of KRAS wild-type, epidermal growth factor receptor (EGFR)-expressing, metastatic colorectal cancer (mCRC) as determined by an FDA-approved test for this use: In combination with FOLFIRI (irinotecan, fluorouracil, leucovorin) for first-line treatment.
How long after erbitux infusion do reactions occur?
Caution must be exercised with every ERBITUX infusion as infusion reactions may occur during or several hours following completion of the infusion.
How long does a rash last after erbitux?
Acneiform rash usually developed within the first 2 weeks of therapy; the rash lasted more than 28 days after stopping ERBITUX in most patients.
How long does it take for acne to develop after erbitux?
Acneiform rash usually developed within the first 2 weeks of therapy; the rash lasted more than 28 days after stopping ERBITUX in most patients.
How long to monitor after erbitux?
Monitor patients for at least 1 hour following each ERBITUX infusion in a setting with resuscitation equipment and other agents necessary to treat anaphylaxis. In patients requiring treatment for infusion reactions, monitor for more than 1 hour to confirm resolution of the reaction. Interrupt the infusion and upon recovery, resume the infusion at a slower rate or permanently discontinue ERBITUX based on severity.
How many patients have adverse reactions to erbitux?
Adverse reactions with fatal outcome were reported in 4% of patients in the ERBITUX combination arm and 3% in the control arm.
How much does Erbitux cost?
Through our revolutionary program, Prescription Hope can obtain Erbitux for individuals at the set price of $50.00 per month direct from the source. To obtain your prescription medications, our highly-trained team works directly with over 180 U.S. based pharmaceutical manufacturers and their pharmacy every day to obtain all your prescriptions at a set, affordable price.
What is Erbitux used for?
Erbitux is a medication that targets proteins in cancer cells and stops the cancer cells from growing. This medication is used to treat colorectal cancer.
What is the best treatment for head and neck cancer?
In combination with radiation therapy for the initial treatment of a certain type of locally or regionally advanced head and neck cancer. In combination with platinum-based chemotherapy and fluorouracil for the initial treatment of patients with a certain type of head and neck cancer whose tumor has returned in the same location or spread ...
How long should you monitor electrolytes after ERBITUX?
Your doctor or nurse should periodically monitor your blood electrolyte levels during and for at least 8 weeks after treatment with ERBITUX, and administer intravenous replacement as needed
How much does ERBITUX affect blood flow?
2% of patients in the ERBITUX plus radiation and cisplatin treatment arm experienced decreased blood flow to the heart, compared to 0.9% in the radiation therapy and cisplatin alone treatment arm
What are the side effects of erbitux?
The most common side effects (all grades of severity) in patients with colorectal cancer that has spread to other parts of the body whose tumors had a protein called Epidermal Growth Factor Receptor (EGFR) treated with ERBITUX and irinotecan were: acne-like rash, feeling weakness or discomfort, diarrhea, and nausea.
How long after erbitux can you get pregnant?
Because ERBITUX can harm an unborn baby, you should use contraception and not become pregnant during treatment with ERBITUX and for at least 2 months after your last dose of ERBITUX. If you become pregnant during your treatment or within 2 months after your last dose, discuss this with your doctor.
How long after erbitux is it safe to wear sunscreen?
Sun exposure may worsen these effects. Patients taking ERBITUX should wear sunscreen and hats to limit sun exposure during treatment and for 2 months after the last dose of ERBITUX
Is Erbitux a combination drug?
ERBITUX is approved in combination with encorafenib, for the treatment of adult patients with colorectal cancer that has spread to other parts of the body. Only patients whose tumors are BRAF V600E mutant (which means they have a BRAF V600E mutation-positive gene) and their condition has progressed from a previous treatment should receive ERBITUX with encorafenib. An FDA-approved test is used to determine if tumors have these particular traits.
What is erbitux used for?
Erbitux (cetuximab) is a member of the EGFR inhibitors drug class and is commonly used for Colorectal Cancer, Head and Neck Cancer, and Squamous Cell Carcinoma.
How much does a free drug card save?
The free Drugs.com Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions.
Is Erbitux valid with insurance?
Prices are for cash paying customers only and are not valid with insurance plans. This Erbitux price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
What are the adverse reactions to cetuximab?
The most common adverse reactions (all grades; incidence ≥25%) seen in patients with carcinomas of the head and neck receiving a cetuximab product in combination with platinum-based therapy and fluorouracil (CT) (n=219) versus CT alone (n=215) (EXTREM E) were acneiform rash (70% vs 2%), nausea (54% vs 47%) , infection (44% vs 27%) , rash (28% vs 2%), diarrhea (26% vs 16%) and anorexia ( 25% vs 14%). The most common grade 3 and 4 adverse reaction for a cetuximab product in combination with CT (≥10%) versus CT alone was infection (11% vs 8%). Because ERBITUX provides approximately 22% higher exposure relative to the cetuximab product used in EXTREME, the data provided above may underestimate the incidence and severity of adverse reactions anticipated with ERBITUX for this indication. However, the tolerability of the recommended dose is supported by safety data from additional studies of ERBITUX.
How long to monitor patients after ERBITUX?
Monitor patients weekly during treatment for hypomagnesemia, hypocalcemia, and hypokalemia, and for at least 8 weeks following the completion of ERBITUX.
How long does a rash last after erbitux?
Acneiform rash usually developed within the first 2 weeks of therapy; the rash lasted more than 28 days after stopping ERBITUX in most patients.
What is ERBITUX used for?
ERBITUX is indicated for the treatment of KRAS wild-type, epidermal growth factor receptor (EGFR)-expressing, metastatic colorectal cancer (mCRC) as determined by an FDA-approved test for this use: In combination with FOLFIRI (irinotecan, fluorouracil, leucovorin) for first-line treatment.
What are the most common adverse reactions to erbitux?
The most common grade 3-4 adverse reactions included: diarrhea (22%) , leukopenia (17%), asthenia/malaise (16%), and acneiform rash (14%). Use in Specific Populations. Lactation: There is no information regarding the presence of ERBITUX in human milk, the effects on the breastfed infant, or the effects on milk production.
How long does it take for acne to develop after erbitux?
Acneiform rash usually developed within the first 2 weeks of therapy; the rash lasted more than 28 days after stopping ERBITUX in most patients.
How long after erbitux can you use contraception?
Advise females of reproductive potential to use effective contraception during treatment with ERBITUX and for 2 months after the last dose of ERBITUX. Verify pregnancy status in females of reproductive potential prior to initiating ERBITUX. Adverse Reactions.
