Cinvanti Copay Assistance Patient assistance programs (PAPs) are usually sponsored by pharmaceutical companies and provide free or discounted medicines and copay programs to low income or uninsured and under-insured people who meet specific guidelines. Eligibility requirements vary for each program.
Full Answer
What is the cinvanti Heron copay assistance program?
Cinvanti Heron Connect Copay Assistance Program: Eligible commercially insured patients may pay $0 copay per prescription saving up to $200 per treatment; your healthcare provider must complete enrollment form; for additional information contact the program at 844-437-6611.
How much does cinvanti cost?
This Cinvanti price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies. The cost for Cinvanti intravenous emulsion (130 mg/18 mL) is around $385 for a supply of 18 milliliters, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
What are the limitations of cinvanti?
Limitations of Use: CINVANTI has not been studied for treatment of established nausea and vomiting. CINVANTI is contraindicated in patients with hypersensitivity to any of the components of CINVANTI. Concurrent use of pimozide with CINVANTI is contraindicated.
Does cinvanti interact with warfarin?
Co-administration of CINVANTI with warfarin, a CYP2C9 substrate, may result in a clinically significant decrease in the International Normalized Ratio (INR) of prothrombin time. Monitor the INR in patients on chronic warfarin therapy in the 2-week period, particularly at 7 to 10 days, following initiation of CINVANTI with each chemotherapy cycle.
How is Cinvanti given?
Administer CINVANTI intravenously either by injection over a two (2) minute period or by infusion over a thirty (30) minute period on Day 1, completing the injection or infusion approximately 30 minutes prior to chemotherapy.
How long does Cinvanti last?
Diluted CINVANTI solution is stable at ambient room temperature for up to 6 hours in 0.9% Sodium Chloride Injection, USP or 12 hours in 5% Dextrose Injection, USP or up to 72 hours if stored under refrigeration in 0.9% Sodium Chloride Injection, USP or in 5% Dextrose Injection, USP.
How often can Cinvanti be given?
DosingHEC & MEC SINGLE-DOSE REGIMEN: CINVANTI IV 130 mg1AGENTDAY 1DAY 4CINVANTI130 mgNoneOral dexamethasone†12 mg8 mg twice daily5-HT3 antagonistSee selected 5-HT3 antagonist PINone1 more row
Is Cinvanti a steroid?
Cinvanti is part of a regimen that includes a corticosteroid and a 5-HT3 antagonist.
How long does Aloxi stay in your system?
Aloxi is a long lasting medication in the same drug family so it will still be active in your system 24-36 hours after treatment.
What is the difference between Cinvanti and Emend?
Emend for Injection contains fosaprepitant, which is converted to aprepitant. Cinvanti uses a novel lipid emulsion formulation of aprepitant to overcome the low water solubility problem of aprepitant without the use of polysorbate 80 or other synthetic surfactants.
How long does IV Emend last?
Administer EMEND for injection on Day 1 as an intravenous infusion over 20 to 30 minutes (adults), 30 minutes (12 years to 17 years) or 60 minutes (6 months to less than 12 years) completing the infusion approximately 30 minutes prior to chemotherapy. In pediatrics, administer EMEND through a central venous catheter.
What is Cinvanti?
CINVANTI is a substance P/neurokinin-1 (NK1) receptor antagonist, indicated in adults, in combination with other antiemetic agents, for the prevention of: acute and delayed nausea and vomiting associated with initial and repeat courses of highly emetogenic cancer chemotherapy (HEC) including high-dose cisplatin as a ...
What is the MEC of a 3 day oral aprepitant?
3-day oral aprepitant with MEC (≥1% and greater than standard therapy): fatigue and eructation.
Can you drink CINVANTI while pregnant?
Avoid use of CINVANTI in pregnant women as alcohol is an inactive ingredient for CINVANTI. There is no safe level of alcohol exposure in pregnancy.
Does citantin reduce aprepitant plasma concentration?
Use of CINVANTI with strong CYP3A4 inducers (e.g., rifampin) may result in a reduction in aprepitant plasma concentrations and decreased efficacy of CINVANTI.
Is pimozide contraindicated with CINVANTI?
Concurrent use of pimozide with CINVANTI is contraindicated.
What is aprepitant cinvanti?
Cinvanti (aprepitant) is a member of the NK1 receptor antagonists drug class and is commonly used for Nausea/Vomiting - Chemotherapy Induced.
Is Cinvanti a generic?
Cinvanti is available as a brand name drug only, a generic version is not yet available. For more information, read about generic Cinvanti availability .
What cancers are treated with aprepitant?
Patients receiving the aprepitant regimen were receiving chemotherapy for a variety of tumor types including 50% with breast cancer, 21% with gastrointestinal cancers including colorectal cancer, 13% with lung cancer and 6% with gynecological cancers.
Can aprepitant inhibit CYP3A4?
Inhibition of CYP3A4 by aprepitant could result in elevated plasma concentrations of pimozide, which is a CYP3A4 substrate, potentially causing serious or life-threatening reactions, such as QT prolongation, a known adverse reaction of pimozide [see Warnings and Precautions (5.1)]. 5 .
What are the side effects of aprepitant?
The most common adverse reactions are: 1 Single-dose fosaprepitant with MEC (≥2%): fatigue, diarrhea, neutropenia, asthenia, anemia, peripheral neuropathy, leukopenia, dyspepsia, urinary tract infection, pain in extremity. 2 3-day oral aprepitant with MEC (≥1% and greater than standard therapy): fatigue and eructation. 3 Single-dose fosaprepitant with HEC: generally similar to 3-day oral aprepitant. In addition, infusion site reactions (3%) occurred. 4 Single-dose CINVANTI (≥2%): headache and fatigue. The safety profile of CINVANTI in healthy subjects who received a single 2-minute injection was similar to that seen with a 30-minute infusion.
What is the Heron commitment program?
The Heron Commitment Program®, which helps mitigate the financial burden of qualifying claim denials when program requirements are met ‡§
What is the MEC of a 3 day oral aprepitant?
3-day oral aprepitant with MEC (≥1% and greater than standard therapy): fatigue and eructation.
Is pimozide contraindicated with CINVANTI?
Concurrent use of pimozide with CINVANTI is contraindicated.
Does citantin reduce aprepitant plasma concentration?
Use of CINVANTI with strong CYP3A4 inducers (e.g., rifampin) may result in a reduction in aprepitant plasma concentrations and decreased efficacy of CINVANTI.
Is Heron Connect patient assistance confidential?
Heron Therapeutics, Inc., reserves the right, at its sole discretion, to discontinue the Heron Connect Patient Assistance Program or change the qualifications at any time. All patient information remains confidential. Product supply for the program depends on availability.
Can you drink CINVANTI while pregnant?
Avoid use of CINVANTI in pregnant women as alcohol is an inactive ingredient for CINVANTI. There is no safe level of alcohol exposure in pregnancy.
