Patient Assistance & Copay Programs for Depakote Sprinkles Patient assistance programs (PAPs) are usually sponsored by pharmaceutical companies and provide free or discounted medicines and copay programs to low income or uninsured and under-insured people who meet specific guidelines. Eligibility requirements vary for each program.
Full Answer
When should Depakote sprinkle capsules be taken?
In epileptic patients previously receiving Depakene (valproic acid) therapy, Depakote Sprinkle Capsules should be initiated at the same daily dose and dosing schedule. After the patient is stabilized on Depakote Sprinkle Capsules, a dosing schedule of two or three times a day may be elected in selected patients. 2.2 General Dosing Advice
How much does Depakote sprinkles cost?
The cost for Depakote Sprinkles oral delayed release capsule 125 mg is around $186 for a supply of 100 capsules, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
What are the contraindications for Depakote sprinkle capsules?
Depakote Sprinkle Capsules is contraindicated in patients with known hypersensitivity to the drug [see Warnings and Precautions (5.12)]. Depakote Sprinkle Capsules is contraindicated in patients with known urea cycle disorders [see Warnings and Precautions (5.6)].
What is the dosage of Depakote Sprinkle for AED withdrawal?
The speed and duration of withdrawal of the concomitant AED can be highly variable, and patients should be monitored closely during this period for increased seizure frequency. Adjunctive Therapy Depakote Sprinkle Capsules may be added to the patient's regimen at a dosage of 10 to 15 mg/kg/day.
How can I get Depakote for free?
You may be eligible to receive free Depakote if you:Are diagnosed with a seizure disorder or be a currently enrolled patient seeking re-enrollment.Have been prescribed Depakote.Have limited or no health insurance coverage.Live in the United States.More items...
What is the difference between Depakote and Depakote sprinkles?
Depakote ER does not have a coating. Depakote Sprinkle Capsules are approved only for the treatment of epilepsy. They are available in 125 mg. They work similar to Depakote delayed release, except that they are in capsules rather than tablets.
How long does it take for Depakote sprinkles to work?
Response and effectiveness. The time it takes for Depakote to reach its peak effects depends on the formulation used. Tablets take 4 hours to reach a peak, Depakote sprinkles take just over three. Food can delay the absorption of Depakote (food has a more significant effect on the tablets compared with the sprinkles).
Do you have to open Depakote sprinkles?
Depakote Sprinkle Capsules (for epilepsy only) may be swallowed whole or opened and the contents sprinkled on soft food. The food with the drug should be eaten immediately without chewing.
Does Depakote give you energy?
The balance between energy intake and expenditure influences body weight; therefore, Depakote likely alters energy intake, energy expenditure, or both. Alterations in energy intake or expenditure can result from, or be associated with, changes in biological mechanisms, including hormone and peptide levels.
Is Depakote an antipsychotic or mood stabilizer?
Valproate is a mood stabilizer medication that works in the brain. It is approved for the treatment of mania associated with bipolar disorder (also known as manic depression), seizures (epilepsy), and migraine headaches. Bipolar disorder involves episodes of depression and/or mania.
Can Depakote change your personality?
Divalproex sodium may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. If you notice any of these side effects, tell your doctor right away.
Does Depakote help anger?
Depakote is a mood stabilizing medication that may be beneficial in treating individuals with disruptive behavior disorders. The purpose of this study is to examine the effectiveness of Depakote in reducing temper outbursts and improving mood in individuals with disruptive behavior disorders.
Does Depakote make you feel good?
Most voted positive review. I've been taking depakote for 9 months and it has some what helped my mood swings, but it has really improved my concentration and anxiety problems. Depakote combined with adequate nutrition and exercise is the ultimate treatment for my bipolar dis order.
What happens if you stop taking Depakote for bipolar?
A: Do not stop taking Depakote without first talking to your doctor. Stopping Depakote suddenly can cause serious problems, including seizures that do not stop (also known as “status epilepticus”). Please see Full Prescribing Information with Medication Guide for the complete list of side effects.
Can you swallow sprinkle capsules?
ACIPHEX SPRINKLE (RABEprazole sodium) delayed-release capsules are used to treat gastroesophageal reflux disease in children 1 to 11 years for up to 12 weeks. Although the product is a capsule, it must NOT be swallowed whole or chewed, nor should the granules be crushed.
Is Depakote sprinkles the same as extended release?
Available in 125 mg strength only, Depakote Sprinkle Capsules work in the same way as Depakote Delayed-Release tablets, although they are in a capsule form instead of a tablet.
What is the difference between Depakote and Depakine Chrono?
The biggest difference between Depakene and Depakote lies in how the body breaks them down. Depakene is made of valproic acid only. Depakote is made by combining valproic acid and sodium valproate (another similar chemical) in a lab.
Are Depakote and divalproex the same thing?
Depakote (divalproex sodium) is a stable coordination compound comprised of sodium valproate and valproic acid used to treat manic episodes associated with bipolar disorder, epilepsy, and migraine headaches. Generic Depakote (termed divalproex sodium) is available under several other names.
What is the generic name of Depakote?
Divalproex sodium is a stable coordination compound comprised of sodium valproate and valproic acid used to treat manic episodes associated with bipolar disorder, epilepsy, and migraine headaches. Divalproex sodium is available under the following different brand names: Depakote, Depakote ER, and Depakote Sprinkles.
What is a good substitute for Depakote?
Keppra.Levetiracetam.Carbamazepine.Gabapentin.Topiramate.Clobazam.
What Is Depakote Sprinkles?
Depakote Sprinkles affects chemicals in the body that may be involved in causing seizures.Depakote Sprinkles is used to treat various types of seiz...
Before Taking This Medicine
You should not use Depakote Sprinkles if you are allergic to it, or if you have: 1. liver disease; 2. a urea cycle disorder; or 3. a genetic mitoch...
How Should I Take Depakote Sprinkles?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dos...
What Happens If I Miss A Dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What Should I Avoid While Taking Depakote Sprinkles?
Drinking alcohol may increase certain side effects of divalproex sodium.Avoid driving or hazardous activity until you know how this medicine will a...
Depakote Sprinkles Side Effects
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin...
What Other Drugs Will Affect Depakote Sprinkles?
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may in...
How to take a missed med?
If you take 2 or more doses daily and you remember within 6 hours of the missed dose, take it immediately. Then take the remainder of the doses for that day at evenly spaced intervals. Do not "double-up" the dose to catch up.
How many Americans can't afford medication?
There are over 100 million Americans that either can‚t afford their medication or are struggling to afford their medication. We aim to help each and every American in that situation.
Can you get Depakote for free?
You may be eligible to receive free Depakote if you: Are diagnosed with a seizure disorder or be a currently enrolled patient seeking re-enrollment.
Does Abbvie pay for Depakote?
If you lost employer-provided health insurance that covered your AbbVie treatment and can no longer pay for Depakote, please call: 1-800-222-6885.
Is copay assistance available for Medicare?
Available to patients with commercial prescription insurance coverage who meet eligibility criteria. Copay assistance program is not available to patients receiving prescription reimbursement under any federal, state, or government-funded insurance programs (for example, Medicare [including Part D], Medicare Advantage, Medigap, Medicaid, TRICARE, Department of Defense, or Veterans Affairs programs) or where prohibited by law. Offer subject to change or discontinuance without notice. Restrictions, including monthly maximums, may apply. This is not health insurance.
How should I take Depakote Sprinkles?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
What is Depakote sprinkles used for?
Depakote Sprinkles tablets and capsules are used to treat seizures in people with epilepsy who are at least 10 years old. This medicine tablets are sometimes used together with other seizure medications.
What other drugs will affect Depakote Sprinkles?
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
What to do if you can't swallow a sprinkle capsule?
If you cannot swallow a sprinkle capsule whole, open it and sprinkle the medicine into a spoonful of pudding or applesauce. Swallow the mixture right away. Do not save it for later use.
Can you use Depakote sprinkles if you have liver disease?
You should not use Depakote Sprinkles if you have liver disease, a urea cycle disorder, or a genetic disorder such as Alpers' disease or Alpers-Huttenlocher syndrome.
Can you take depakote while pregnant?
Using Depakote Sprinkles during pregnancy may increase the risk of serious birth defects that can develop early in pregnancy, even before you know you are pregnant. Using this medicine during pregnancy can also affect cognitive ability (reasoning, intelligence, problem-solving) later in your child's life.
When was the 2020 meds review?
Medically reviewed by Drugs.com on Feb 27, 2020. Written by Cerner Multum.
What to know before taking Divalproex?
Before you take this drug, tell your doctor if you have: a bleeding disorder, a history of a brain disorder, any allergies. This medication is not recommended for use if you have the following medical conditions: liver disease, pancreatitis, certain metabolic disorder (urea cycle disorder). Use caution driving motor vehicles or performing tasks that require alertness. Limit your consumption of alcoholic beverages. Before having surgery, including dental surgery, tell the doctor that you take this drug. Use with extreme caution in children under 2 years old as the potential for serious liver problems exist. This drug is not recommended for use during pregnancy. Consult your doctor before taking this drug. Divalproex is excreted into human breast milk. Consult your doctor before breast-feeding.
How many Americans can't afford medication?
There are over 100 million Americans that either can‚t afford their medication or are struggling to afford their medication. We aim to help each and every American in that situation.
How do I apply for the Depakote Sprinkles patient assistance program?
Applying online for the Depakote Sprinkles patient assistance program is fast and easy. Start by filling in our enrollment application. Tell us about any medications you’re taking, including Depakote Sprinkles, and the details of your healthcare provider, insurance coverage, and household income. This is required by the pharmaceutical manufacturers who ship your medication.
Can NiceRx help me get Depakote Sprinkles if I have insurance?
We may be able to help even if your insurance company won’t pay for your Depakote Sprinkles medication, you have a high copay or coinsurance responsibility, or even if you don’t have insurance. Apply online to find out more.
Does NiceRx offer Depakote Sprinkles coupons?
We are a service provider that helps eligible individuals access the Depakote Sprinkles patient assistance program. NiceRx does not offer Depakote Sprinkles coupons, Depakote Sprinkles discount cards, or Depakote Sprinkles copay cards. We also don’ t offer printable Depakote Sprinkles manufacturer coupons, Depakote Sprink les discounts, rebates, Depakote Sprinkles savings cards, trial offers, or free Depakote Sprinkles samples.
What is a depakote sprinkle?
Depakote ® Sprinkle Capsules (divalproex sodium delayed release capsules) provide the medicine that your healthcare provider has prescribed. The sprinkles are flavorless. Soft foods such as applesauce or pudding are best to use for mixing and taking Depakote Sprinkle Capsules.
How much valproic acid is in Depakote?
Depakote Sprinkle Capsules are for oral administration. Depakote Sprinkle Capsules contain specially coated particles of divalproex sodium equivalent to 125 mg of valproic acid in a hard gelatin ...
How often can you reduce AED?
Concomitant antiepilepsy drug (AED) dosage can ordinarily be reduced by approximately 25% every 2 weeks. This reduction may be started at initiation of Depakote Sprinkle Capsules therapy, or delayed by 1 to 2 weeks if there is a concern that seizures are likely to occur with a reduction.
Does Valproate cause hepatic failure?
General Population: Hepatic failure resulting in fatalities has occurred in patients receiving valproate and its derivatives. These incidents usually have occurred during the first six months of treatment. Serious or fatal hepatotoxicity may be preceded by non-specific symptoms such as malaise, weakness, lethargy, facial edema, anorexia, and vomiting. In patients with epilepsy, a loss of seizure control may also occur. Patients should be monitored closely for appearance of these symptoms. Serum liver tests should be performed prior to therapy and at frequent intervals thereafter, especially during the first six months [see Warnings and Precautions ( 5.1 )].
Can Valproate cause pancreatitis?
Cases of life-threatening pancreatitis have been reported in both children and adults receiving valproate. Some of the cases have been described as hemorrhagic with a rapid progression from initial symptoms to death. Cases have been reported shortly after initial use as well as after several years of use. Patients and guardians should be warned that abdominal pain, nausea, vomiting, and/or anorexia can be symptoms of pancreatitis that require prompt medical evaluation. If pancreatitis is diagnosed, valproate should ordinarily be discontinued. Alternative treatment for the underlying medical condition should be initiated as clinically indicated [see Warnings and Precautions ( 5.5 )].
Can you give valproate to a woman?
Valproate should not be administered to a woman of childbearing potential unless other medications have failed to provide adequate symptom control or are otherwise unacceptable. In such situations, effective contraception should be used [see Warnings and Precautions ( 5.2, 5.3, 5.4 )].
Can Valproate cause heart block?
Overdosage with valproate may result in somnolence, heart block, deep coma, and hypernatremia. Fatalities have been reported; however patients have recovered from valproate levels as high as 2,120 ...
Why should valproate be reduced?
Due to a decrease in unbound clearance of valproate and possibly a greater sensitivity to somnolence in the elderly , the starting dose should be reduced in these patients. Dosage should be increased more slowly and with regular monitoring for fluid and nutritional intake, dehydration, somnolence, and other adverse reactions. Dose reductions or discontinuation of valproate should be considered in patients with decreased food or fluid intake and in patients with excessive somnolence. The ultimate therapeutic dose should be achieved on the basis of both tolerability and clinical response [see Warnings and Precautions (5.14), Use in Specific Populations (8.5) and Clinical Pharmacology (12.3)].
How is valproate metabolized?
Valproate is metabolized almost entirely by the liver. In adult patients on monotherapy, 30-50% of an administered dose appears in urine as a glucuronide conjugate. Mitochondrial β-oxidation is the other major metabolic pathway, typically accounting for over 40% of the dose. Usually, less than 15-20% of the dose is eliminated by other oxidative mechanisms. Less than 3% of an administered dose is excreted unchanged in urine.
Does carbapenem reduce valproate?
Carbapenem antibiotics (for example, ertapenem, imipenem, meropenem; this is not a complete list) may reduce serum valproate concentrations to subtherapeutic levels, resulting in loss of seizure control. Serum valproate concentrations should be monitored frequently after initiating carbapenem therapy. Alternative antibacterial or anticonvulsant therapy should be considered if serum valproate concentrations drop significantly or seizure control deteriorates [see Drug Interactions (7.1)].
Does Valproate cause thrombocytopenia?
Valproate is associated with dose-related thrombocytopenia. In a clinical trial of valproate as monotherapy in patients with epilepsy, 34/126 patients (27%) receiving approximately 50 mg/kg/day on average, had at least one value of platelets ≤ 75 x 109/L. Approximately half of these patients had treatment discontinued, with return of platelet counts to normal. In the remaining patients, platelet counts normalized with continued treatment. In this study, the probability of thrombocytopenia appeared to increase significantly at total valproate concentrations of ≥ 110 mcg/mL (females) or ≥ 135 mcg/mL (males). The therapeutic benefit which may accompany the higher doses should therefore be weighed against the possibility of a greater incidence of adverse effects. Valproate use has also been associated with decreases in other cell lines and myelodysplasia.
Does Valproate cause pancreatitis?
Cases of life-threatening pancreatitis have been reported in both children and adults receiving valproate. Some of the cases have been described as hemorrhagic with rapid progression from initial symptoms to death. Some cases have occurred shortly after initial use as well as after several years of use. The rate based upon the reported cases exceeds that expected in the general population and there have been cases in which pancreatitis recurred after rechallenge with valproate. In clinical trials, there were 2 cases of pancreatitis without alternative etiology in 2,416 patients, representing 1,044 patient-years experience. Patients and guardians should be warned that abdominal pain, nausea, vomiting, and/or anorexia can be symptoms of pancreatitis that require prompt medical evaluation. If pancreatitis is diagnosed, Depakote should ordinarily be discontinued. Alternative treatment for the underlying medical condition should be initiated as clinically indicated [see Boxed Warning].
Can you take Valproate while pregnant?
Because of the risk to the fetus of decreased IQ and major congenital malformations (including neural tube defects), which may occur very early in pregnancy, valproate should not be administered to a woman of childbearing potential unless the drug is essential to the management of her medical condition. This is especially important when valproate use is considered for a condition not usually associated with permanent injury or death (e.g., migraine). Women should use effective contraception while using valproate. Women who are planning a pregnancy should be counseled regarding the relative risks and benefits of valproate use during pregnancy, and alternative therapeutic options should be considered for these patients [see Boxed Warning and Use in Specific Populations (8.1)].
Does valproate affect IQ?
Valproate can cause decreased IQ scores following in utero exposure. Published epidemiological studies have indicated that children exposed to valproate in utero have lower cognitive test scores than children exposed in utero to either another antiepileptic drug or to no antiepileptic drugs. The largest of these studies1 is a prospective cohort study conducted in the United States and United Kingdom that found that children with prenatal exposure to valproate (n=62) had lower IQ scores at age 6 (97 [95% C.I. 94-101]) than children with prenatal exposure to the other antiepileptic drug monotherapy treatments evaluated: lamotrigine (108 [95% C.I. 105–110]), carbamazepine (105 [95% C.I. 102–108]), and phenytoin (108 [95% C.I. 104–112]). It is not known when during pregnancy cognitive effects in valproate-exposed children occur. Because the women in this study were exposed to antiepileptic drugs throughout pregnancy, whether the risk for decreased IQ was related to a particular time period during pregnancy could not be assessed.
Important Note
- The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug. DIVALPROEX SODIUM - ORAL SPRINKLE CAPSU…
How to Use
- May be taken with food if stomach upset occurs. Capsules may be swallowed whole or open the capsules and sprinkle entire contents on a teaspoonful of soft food such as applesauce or pudding. Swallow the drug/food mixture immediately (do not chew). Do not keep for future use. It is important to take all doses on time to keep the level of medication in your blood constant. Tak…
Side Effects
- Mild stomach pain, loss of appetite, change in menstrual periods, diarrhea, mild hair loss, unsteadiness, dizziness, drowsiness, rash or headache might occur. If any of these effects continue or are bothersome, inform your doctor. Very unlikely but report: yellowing eye/skin, blurred or double vision, severe stomach pain, unusual bleeding or bruisi...
Precautions
- Before you take this drug, tell your doctor if you have: a bleeding disorder, brain disorder, any allergies. This medication is not recommended for use if you have the following medical conditions: liver disease, pancreatitis, certain metabolic disorder (urea cycle disorder). Use caution driving motor vehicles or performing tasks that require alertness. Limit your consumptio…
Drug Interactions
- Be sure to tell your doctor of all over-the-counter or prescription drugs you are taking, especially of: other medication for seizures (phenobarbital, primidone, phenytoin, carbamazepine, ethosuximide, clonazepam), anticoagulants ("blood thinners"), aspirin, chlorpromazine, cimetidine, mefloquine, drugs used for colds or allergies (antihistamines), sleeping pills, muscle relaxants, n…
Overdose
- If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include deep sleep, irregular heartbeat, and loss of consciousness.
Notes
- It is recommended to wear or carry medication identification indicating you are taking this drug. Lab tests may be done, especially in the first few months to check if the drug is working properly. Do not allow anyone else to take this medication.
Missed Dose
- If you miss a dose and your dosing schedule is 1 dose daily, take the missed dose as soon as remembered. If you do not remember until the next day, skip the missed dose and resume your usual dosing schedule. If you take 2 or more doses daily and you remember within 6 hours of the missed dose, take it immediately. Then take the remainder of the doses for that day at evenly sp…
Storage
- Store at room temperature between 59 and 86 degrees F (between 15 and 30 degrees C) away from moisture and sunlight. Do not store in the bathroom.
Medical Alert
- Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).
Important Note
- The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug. DIVALPROEX SODIUM - ORAL ENTERIC-COATED …
Uses
- This medication is used to treat seizure disorders, the manic stage of manic-depressive disorder (bipolar disorder) and to prevent migraine headaches.
How to Use
- May be taken with food if stomach upset occurs. This medication should be swallowed whole. If chewed or crushed it may irritate the mouth or throat. It is important to take all doses on time to keep the level of medication in your blood constant. Take doses at evenly spaced intervals.
Side Effects
- Mild stomach pain, loss of appetite, change in menstrual periods, diarrhea, mild hair loss, unsteadiness, dizziness, drowsiness, rash or headache might occur. If any of these effects continue or are bothersome, inform your doctor. Very unlikely but report: yellowing eye/skin, blurred or double vision, severe stomach pain, unusual bleeding or bruising. Tell your doctor im…
Precautions
- Before you take this drug, tell your doctor if you have: a bleeding disorder, a history of a brain disorder, any allergies. This medication is not recommended for use if you have the following medical conditions: liver disease, pancreatitis, certain metabolic disorder (urea cycle disorder). Use caution driving motor vehicles or performing tasks that require alertness. Limit your consu…
Drug Interactions
- Be sure to tell your doctor of all over-the-counter and prescription drugs you are taking, especially of: other medications for seizures, aspirin, chlorpromazine, anticoagulants ("blood thinners"), cimetidine, mefloquine, drugs used for colds or allergies (antihistamines), sleeping pills, muscle relaxants, narcotic pain relievers (e.g., codeine), sedatives, tranquilizers. This drug may alter cert…
Overdose
- If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include deep sleep, irregular heartbeat, and loss of consciousness.
Notes
- It is recommended to wear or carry medication identification indicating you are taking this drug. Lab tests may be done, especially in the first few months to check if the drug is working properly. Do not allow anyone else to take this medication.
Missed Dose
- If you miss a dose and your dosing schedule is 1 dose daily, take the missed dose as soon as remembered. If you do not remember until the next day, skip the missed dose and resume your usual dosing schedule. If you take 2 or more doses daily and you remember within 6 hours of the missed dose, take it immediately. Then take the remainder of the doses for that day at evenly sp…
Storage
- Store at room temperature between 59 and 86 degrees F (between 15 and 30 degrees C) away from moisture and sunlight. Do not store in the bathroom.