Full Answer
What is the copay support for Gamunex-C* patients?
Patients can receive up to $10,000 of copay support per calendar year on their prescription for GAMUNEX-C* Patients may be eligible for IV administration in CIDP and both IV and Sub Q administration in PIDD SUBMIT a claim to the primary payer first.
What is Gamunex-C used to treat?
GAMUNEX®-C (immune globulin injection [human], 10% caprylate/chromatography purified) is approved to treat primary humoral immunodeficiency disease (PIDD) in patients 2 years of age and older. If you have PIDD, you may take GAMUNEX-C under the skin (subcutaneously) or in a vein (intravenously).
What do I need to apply for the Grifols Gamunex-C program?
You will need to explain your medical and financial situation. Grifols Gamunex-C Connexions Program: Provides the uninsured or underinsured the access to therapy that they need. (For CIDP patients only) Shire’s Patient Assistance Program: You may qualify for this program if you 1. Have a current prescription for a Shire hematology product 2.
What are the contraindications for the use of Gamunex-C?
GAMUNEX-C is contraindicated in patients who have had an anaphylactic or severe systemic reaction to the administration of human immune globulin. It is contraindicated in IgA-deficient patients with antibodies against IgA and history of hypersensitivity. Severe hypersensitivity reactions may occur with IVIG products, including GAMUNEX-C.
Is gamunex-C covered by Medicare?
Do Medicare prescription drug plans cover Gamunex-C? No. In general, Medicare prescription drug plans (Part D) do not cover this drug.
How long does it take for gamunex-C to work?
Your doctor may measure your muscle strength to see if you are getting stronger in the arms and legs. Among the patients who responded to GAMUNEX-C in a clinical study, some patients started to improve by week 3, and most started to improve by week 6.
What does gamunex-C do?
This medication is used in people with a certain type of weakened immune system (primary immune deficiency) to strengthen it and to lower the risk of infection. This medication is made from human blood that has a high level of antibodies which help fight infections.
How long does it take to infuse gamunex?
Rate of Administration It is recommended that GAMUNEX (immune globulin intravenous (human) 10%) should initially be infused at a rate of 0.01 mL/kg per minute (1 mg/kg per minute) for the first 30 minutes. If well-tolerated, the rate may be gradually increased to a maximum of 0.08 mL/kg per minute (8 mg/kg per minute).
What are the long term effects of IVIG?
IVIg can sometimes cause a rise in blood pressure, which can lead to an increase in the risk of heart attack or stroke. It can also increase the risk of blood clots. If you have any concerns about your treatment or its side effects, you should discuss these with your doctor, rheumatology nurse or pharmacist.
How do I know if IVIG is working?
When Can I See the Results? IVIG patients often begin to see results from their treatments anywhere from 6 months to a year. During this time, your doctor will closely monitor and track to see if there are improvements in relieving the symptoms associated with your primary diagnosis.
Can you drink alcohol while on IVIG?
There is no reason to avoid alcohol before or after IVIg. However, only take alcohol in moderation.
How fast can you give IVIG?
For the first infusion or if greater than 8 weeks since last treatment, it is recommended to initiate infusion at 0.5 mL/kg/hr for 30 minutes. Gradually increase rate every 15-30 minutes, as tolerated, according to steps in table. It is not recommended to advance to the maximum rate with the first infusion.
How often is gamunex given?
GAMUNEX-C may be administered as a maintenance infusion of 1 g/kg (10 mL/kg) administered over 1 day or divided into two doses of 0.5 g/kg (5 mL/kg) given on two consecutive days, every 3 weeks.
Can you do IVIg at home?
Can IVIG be given at home? Yes, in most cases, immunoglobulin therapies can safely be administered in the home setting with the careful monitoring and supervision of a skilled nursing professional.
How much IVIg should I get?
IVIG doses range from 400 to 800 mg/kg/month are used for immune deficiencies. Doses may be given every three to four weeks. In patients who require auto-inflammatory effects of IVIG, high doses are typically required. This will usually range from 1-2 g/kg as a single dose.
How long does IVIg take to work for CIDP?
Based on a Cochrane review, disability is reduced in 54% of CIDP patients within the first 6 weeks after IVIg therapy [Eftimov et al. 2013]. Several trials and case series have demonstrated a response rate of even 60% during a short observation period over 24 weeks of IVIg treatment [Dyck et al.
How do you administer gamunex?
IV infusion requires only 1 site, 1 infusion, once every 3 weeks. GAMUNEX-C IV can be administered in the home, hospital, or infusion clinic by a healthcare professional. The high-dose regimen (1g/kg x 1-2 days) is not recommended for individuals with expanded fluid volumes or where fluid volume may be a concern.
What is gamunex infusion?
Gamunex-C is an immune globulin injection used for treating primary humoral immunodeficiency (PI) in patients two years of age and older, idiopathic thrombocytopenic purpura (ITP) in adults and children, and chronic inflammatory demyelinating polyneuropathy (CIDP) in adult patients.
Does gamunex-C need to be refrigerated?
Gamunex®-c GAMUNEX-C may be stored for 36 months at 2 - 8°C (36 - 46°F) from the date of manufacture, AND product may be stored at temperatures not to exceed 25°C (77°F) for up to 6 months anytime during the 36 month shelf life, after which the product must be immediately used or discarded.
Does gamunex-C have to be refrigerated?
-Gamunex-C or Gammaked should be at room temperature (up to 77 degrees F) at the time of administration. Do not use if turbid, discolored, or previously frozen. Also, do not use if the solution contains particulates. The solution should be clear and colorless to a pale yellow.
Important Note
The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.
Uses
This medication is used to boost the body's natural defense system against infection in persons with a weakened immune system. It is also used to increase the blood count in persons with the blood disorder known as idiopathic thrombocytopenic purpura.
How To Use
This medication is administered by injection into a vein by a health care professional. Rapid infusion/high concentrations of this drug may result in serious blood clots.
Side Effects
Redness, warmth, pain and tenderness may occur at the site of injection. Fever, chills, headache, weakness and nausea may also occur. If these effects persist or worsen, inform your doctor promptly.
Precautions
Tell your doctor your medical history, especially of: blood disorders, kidney disease, diabetes, severe infections, heart problems, blood clots, any allergies. Caution is advised when used in elderly patients because this group may be more sensitive to the drug's effect. This medication should be use only when clearly needed during pregnancy.
Drug Interactions
Tell your doctor of all prescription and nonprescription medications you may use, especially of: vaccines, drugs that affect the kidneys (e.g., amphotericin, tobramycin), "water pills" (e.g., furosemide). Do not start or stop any medicine without doctor or pharmacist approval.
Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately.
What is the Kaiser Foundation Consumer Guide?
Kaiser Foundation Consumer Guide (United States only): Helps patients handle disputes with their employer or private health plan, by state. https://www.kff.org/our-programs/
What is Needy Meds?
https://www.nosscr.org/. (201) 567-4228. Needy Meds: Provides a free drug discount card that offers a discount of up to 80% at more than 63,000 pharmacies nationwide. They also maintain a website of free information on programs that help people who cannot afford medications and healthcare costs. www.needymeds.org.
How to get more information about Gamunex C?
To receive farther information about Gamunex-C and its effects, talk to your doctor.
What is Gamunex C used for?
Gamunex-C is a prescription medication used to treat primary humoral immunodeficiency disease (PIDD) in patients 2 years of age and older, idiopathic thrombocytopenic purpura (ITP) in adults and children, and chronic inflammatory demyelinating polyneuropathy (CIDP) in adults. This medication comes in the form of an injection.
Is Prescription Hope A Gamunex-C Coupon Card, Generic, Or Insurance Product?
Prescription Hope is not a Gamunex-C coupon card or insurance policy. Our program is also not a Gamunex-C Generic. Prescription Hope is a national advocacy program that works with any coverage you may already have. Although Prescription Hope is not a Gamunex-C coupon, individuals looking for a Gamunex-C coupon can find more savings through Prescription Hope!
Can Prescription Hope Get My Gamunex-C If I Have Health Insurance Coverage?
Because Prescription Hope is not a health insurance plan, our program works alongside any coverage you may currently have to obtain your Gamunex-C medication at an affordable price. Our national advocacy program does not have medication tiers, copays, or deductibles.
What are the side effects of CIDP?
The most common side effects may include headache, pyrexia, hypertension, chills, rash, nausea, arthralgia, and asthenia (in CIDP); cough, rhinitis, pharyngitis, headache, asthma, nausea, fever, diarrhea, and sinusitis with intravenous use (in PIDD) and local infusion-site reactions, fatigue, headache, upper respiratory tract infection, arthralgia, diarrhea, nausea, sinusitis, bronchitis, depression, allergic dermatitis, migraine, myalgia, viral infection, and pyrexia with subcutaneous use (in PIDD); and headache, ecchymosis, vomiting, fever, nausea, rash, abdominal pain, back pain, and dyspepsia (in ITP).
Is Gamunex C generic?
There does not appear to be a generic version of Gamunex-C that has been approved. Please note: Fraudulent online pharmacies may try to sell you an illegal Gamunex-C generic. Do not purchase medications from these pharmacies as they may be harmful. Ask your doctor for advice when it comes to purchasing your medications.
Can you take Gamunex C if you are allergic to it?
Do not receive treatment with Gamunex-C if you have had a reaction to the administration of human immune globulin or if you are allergic to any of the ingredients. Your doctor should monitor your health including your renal function.
What are the adverse reactions to GAMUNEX C?
In clinical studies, the most common adverse reactions with GAMUNEX-C were headache, pyrexia, hypertension, chills, rash, nausea, arthralgia, and asthenia (in CIDP); cough, rhinitis, pharyngitis, headache, asthma, nausea, fever, diarrhea, and sinusitis with intraven ous use (in PIDD) and local infusion-site reactions, fatigue, headache, upper respiratory tract infection, arthralgia, diarrhea, nausea, sinusitis, bronchitis, depression, allergic dermatitis, migraine, myalgia, viral infection, and pyrexia with subcutaneous use (in PIDD); and headache, ecchymosis, vomiting, fever, nausea, rash, abdominal pain, back pain, and dyspepsia (in ITP).
Is gabunex C contraindicated?
GAMUNEX-C is contraindicated in patients who have had an anaphylactic or severe systemic reaction to the administration of human immune globulin. It is contraindicated in IgA-deficient patients with antibodies against IgA and history of hypersensitivity.
Can you get copay assistance if you are on Medicare?
Patients are ineligible for copay assistance if they participate in Medicare, Medicaid, Medigap, Veterans Affairs, Department of Defense, Tricare, or any other federal or state-funded programs
Does Gamunex cause pulmonary edema?
There have been reports of aseptic meningitis, hemolytic anemia, and noncardiogenic pulmonary edema (transfusion-related acute lung injury [TRALI]) in patients administered with IVIG, including GAMUNEX-C.
Does GAMUNEX C cause thrombosis?
Thrombosis may occur with immun e globulin products, including GAMUNEX-C. Risk factors may include: advanced age, prolonged immobilization, hypercoagulable conditions, history of venous or arterial thrombosis, use of estrogens, indwelling central vascular catheters, hyperviscosity, and cardiovascular risk factors. Thrombosis may occur in the absence of known risk factors. For patients at risk of thrombosis, administer GAMUNEX-C at the minimum dose and infusion rate practicable. Ensure adequate hydration in patients before administration. Monitor for signs and symptoms of thrombosis and assess blood viscosity in patients at risk for hyperviscosity.
