Humulin R U500 Patient Assistance. This insulin is used to treat high blood sugar in people with type 1 and type 2 diabetes who need more than 200 units of insulin per day. The safety and efficacy of Humulin R U-500 used in combination with other insulins or delivered by an insulin infusion pump has not been determined.
Full Answer
Are there any patient assistance programs for Humulin R U-500 kwikpen?
Patient Assistance Programs for Humulin R U-500 KwikPen. Patient assistance programs (PAPs) are usually sponsored by pharmaceutical companies and provide free or discounted medicines to low income or uninsured and under-insured people who meet specific guidelines. Eligibility requirements vary for each program.
What is Humulin U500 used to treat?
Humulin R U500 Patient Assistance. This insulin is used to treat high blood sugar in people with type 1 and type 2 diabetes who need more than 200 units of insulin per day. The safety and efficacy of Humulin R U-500 used in combination with other insulins or delivered by an insulin infusion pump has not been determined.
How much does Humulin R 500 cost?
Humulin R U-500 (Concentrated) Prices. The cost for Humulin R U-500 (Concentrated) subcutaneous solution (human recombinant 500 units/mL) is around $1,561 for a supply of 20 milliliters, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
Who do I call for questions about Humulin®?
* Call 1-866-923-1953 if you have any savings card questions. Important Facts About Humulin ® (HUE-mu-lin) R U-500. It is also known as insulin human injection (500 units/mL).
Does Eli Lilly have a patient assistance program?
Lilly Cares® Foundation Patient Assistance Program (Lilly Cares) is a nonprofit charitable organization that provides prescribed Lilly medications for free for up to 12 months to qualifying U.S. patients.
How long does it take for Humulin R U500 to work?
U500 Humulin R insulin is only available in a vial of insulin. U500 Humulin R insulin onset (when the insulin starts working) is about 30-45 minutes. U500 Humulin R peak of action (when the insulin is at its strongest) varies from 2-4 hours.
How do you use a Humulin R U500 pen?
Administer Humulin R U-500 subcutaneously two or three times daily 30 minutes before a meal into the thigh, upper arm, abdomen, or buttocks. Be sure to refer to the Instructions for Use that came with your U-500 KwikPen or vial . Of course, if you have any questions, please be sure to talk to your doctor.
Do you need a prescription for Humulin R?
Humulin R is a brand-name medication that's available both over the counter and by prescription. It's used to help manage blood sugar levels in adults and children with either type 1 or type 2 diabetes. Humulin R comes as a liquid solution.
Do you have to eat with Humulin?
Inject this medication under the skin as directed by your doctor, usually 30 minutes before meals. Because this insulin is fast-acting, not eating right after a dose of this insulin may lead to low blood sugar (hypoglycemia).
What is the difference between u100 and U-500 insulin?
U-500 is 5 times more concentrated than standard U-100 insulin. When insulin is concentrated, it takes less liquid per dose than standard U-100 insulin to help reduce your blood sugar levels. With U-500, you can inject up to 80% less liquid and still get the dose you need.
How do you take U-500 insulin?
For example, if a patient requires 150 units insulin three times a day, and the prescriber wishes to use U-500, the correct way to write the prescription is as follows: “Regular Insulin U-500, 150 units, inject 0.3 ml subcutaneously, three times daily before meals.” Using this example, confusion will arise, because a ...
How do you administer Humulin R insulin?
Inject HUMULIN R subcutaneously approximately 30 minutes before meals into the thigh, upper arm, abdomen, or buttocks. Rotate injection sites within the same region from one injection to the next to reduce the risk of lipodystrophy and localized cutaneous amyloidosis.
How long does U-500 insulin last?
Concentrated (U-500) insulin is a long-acting insulin that starts to work several hours after injection and keeps working evenly for 24 hours. U-500 insulin is five times more concentrated than regular U-100 insulin.
Can I purchase insulin over the counter?
There are two types of human insulin available over the counter: one made by Eli Lilly and the other by Novo Nordisk.
How many pens are in a u500 box?
It's a fatter 20 ml vial compared to U-100 insulin vials. One 20 ml vial of Humulin R U-500 is approximately $1500 (10,000 units/vial). One box of two 3 ml Kwik pens (3000units/box) is approximately $600.
Can I buy insulin syringes over the counter?
Licensed pharmacists may sell hypodermic needles and syringes to adults aged 18 and older without a prescription.
How long is Humulin R u500 good for?
Store opened vials in the refrigerator or at room temperature (less than 86°F [30°C]) for up to 40 days. Throw away the opened vial after 40 days, even if there is still insulin left in the vial. Always use a U-500 syringe to inject Humulin R U-500 insulin.
Is Humulin R 500 fast acting?
Inject this medication under the skin as directed by your doctor, usually 2 to 3 times daily before meals. Because this insulin is fast-acting, do not use this insulin product if you are unable to eat within 30 minutes after the injection or if you have low blood sugar.
How does Humulin r500 work?
Humulin R U-500 works by moving sugar from foods out of your blood and into your cells. Once inside your cells, sugar can be used as energy or stored. This lowers the amount of sugar in your blood. The use of Humulin R U-500 can help keep your blood sugar levels within a healthy range.
What happens if my blood sugar is over 500?
You might develop a serious problem called diabetic ketoacidosis (or DKA). This usually happens in people with Type 1 diabetes and those with glucose levels over 500. If you have DKA, chemicals called ketones start to make a lot of acid in your body. The acid and high blood glucose can make you very sick.
What is Humulin R U 500?
Humulin R U-500 is a prescription insulin used in adults and children who need more than 200 units of insulin a day to control high blood sugar for their diabetes mellitus.
What happens if you take Humulin R U-500?
Tell your doctor if you are short of breath, have swelling in your ankles, or have gained weight suddenly. Heart failure when taking a medication from a class of drugs called thiazolidinediones (TZDs) with Humulin R U-500. This may occur in some people even if they have not had heart problems before.
What is the syringe for Humulin R?
When using the Humulin R U-500 vial: There is a special syringe to measure Humulin R U-500 called the "U-500 insulin syringe.". Only use the U-500 insulin syringe to inject Humulin R U-500. If you do not use the right syringe, you may take the wrong dose of Humulin R U-500.
What are the side effects of Humulin R U 500?
Common side effects. The most common side effects of Humulin R U-500 include: Low blood sugar (hypoglycemia). Talk to your doctor about low blood sugar symptoms and treatment. Symptoms may be different for each person. Allergic reactions, such as redness and swelling at the site where you inject.
When injecting Humulin R U-500, should you use a new needle?
Always use a new needle when injecting Humulin R U-500. This will help you avoid infection.
Can you take Humulin R U-500 off a kwikpen?
When using the Humulin R U-500 KwikPen: The Humulin R U-500 KwikPen is made to dial and deliver the correct dose of Humulin R U-500 insulin. Do not remove Humulin R U-500 from the KwikPen to inject with any syringe. This could cause severe overdose and may lead to death.
How to contact Humulin?
For more information, call 1-800-545-5979 or go to humulin.com.
What Is Humulin R (insulin Regular)?
Humulin R is the brand name of a medicine that contains insulin regular (a short-acting form of insulin). Insulin is a hormone that's produced by the body in the pancreas. It works to lower levels of sugar in the blood. This prescription medicine is injected to improve blood sugar control in adults with diabetes. The U.S. Food and Drug Administration (FDA) first approved human insulin in 1982. Humulin R is marketed by Ely Lilly and Company. Humulin R Warnings Humulin R shouldn't be used during an episode of hypoglycemia (low blood sugar). Low blood sugar is a common side effect of insulin. Symptoms may include: Hunger Headache Weakness Sweating Irritability Tremors Trouble concentrating Fast heartbeat Fainting Seizures Look out for signs of low blood sugar, and carry candy or glucose tablets in case you have an episode. You may also experience signs of hyperglycemia (high blood sugar), which often include: Hunger Increased thirst Dry mouth Fruity breath odor Dry skin Blurred vision Weight loss Increased urination Drowsiness You'll need to monitor your blood sugar levels often while taking this medicine. It's important that you keep Humulin R with you at all times. Be sure to get your prescription refilled before you run out of this medicine. Don't change the brand of insulin or type of syringe you're using without first talking to your healthcare provider. They may not be interchangeable. Before taking Humulin R, tell your doctor if you have, or have ever had: Kidney or liver disease Heart failure, or other heart problems Nerve, adrenal, pituitary, or thyroid problems Eye problems caused by diabetes Allergies to medications Let your doctor know about all the medicines you're taking while using Humulin R, especially certain oral diabetes drugs, such as Actos (pioglitazon Continue reading >>
What is the FDA approved insulin?
U.S. Food And Drug Administration Approves Humulin R U-500 KwikPen The U.S. Food and Drug Administration (FDA) has approved Eli Lilly and Company's (NYSE: LLY) Humulin R U-500 KwikPen (insulin human injection) 500 units/mL, a pre-filled device containing Humulin R U-500, a highly concentrated formulation of insulin. Humulin R U-500 is the only FDA-approved insulin that is five-times more concentrated than standard U-100 insulin. This insulin is used to treat high blood sugar in people with type 1 and type 2 diabetes who need more than 200 units of insulin per day. The safety and efficacy of Humulin R U-500 used in combination with other insulins or delivered by an insulin infusion pump has not been determined. "People with diabetes and severe insulin resistance who have become poorly responsive to the effects of insulin may require much higher insulin doses more than 200 units per day to help keep their blood sugar levels on target," said Jeffrey A. Jackson, MD, FACE, CDE, Medical Fellow, US Medical Affairs, Lilly Diabetes. "For these patients, the U-500 KwikPen is now available as a convenient alternate option to deliver a large dose of insulin in a reasonable volume. It was specifically designed as a dedicated dosing device to eliminate the need for dose conversion, as compared to use of the vial and syringe options, which some people may find to be an improvement." Until now, Humulin R U-500 was only available in a vial, administered with either a U-100 insulin syringe or a volumetric (tuberculin) syringe that requires conversion to respective syringe "unit markings" or volume markings. Although each U-500 KwikPen holds 1500 units of insulin (the amount in five U-100 insulin pens), it is the same size as other KwikPens and dials in five-unit increments. The U-500 Kwi Continue reading >>
How long does Novolin work?
This medication is fast acting and begins to work within 30 minutes of being injected, peaks in 2-3 hours while lasting about up to 8 hours. Novolin R is used to treat diabetes mellitus in children and adults. In addition, this medication may also be used to treat type 1 diabetes. This medicine is not right for everyone. Do not use it if you had an allergic reaction to any insulin. IV: If you are in the hospital, a nurse or other health professional may give you this medicine through a needle placed in a vein. Your healthcare provider will work with you to personalize your dose and treatment based on your insulin needs and lifestyle. You will be taught how to give yourself the injections. Make sure you understand all instructions. Ask the doctor, nurse, or pharmacist if you have questions. Opened medicine: KwikPen: Store at room temperature in a cool place, away from light and heat. Do not store in the refrigerator. Throw away an opened pen after 28 days, even if there is still insulin in it. Humulin R Concentrated U-500 vial: Store in the refrigerator. Do not freeze. You may also store at room temperature in a cool place, away from light and heat. Throw away any opened vial after 40 days.Humulin vials: Store in the refrigerator. Do not freeze. You may also store it at room temperature in a cool place, away from heat and light for up to 31 days. Novolin: Store at room temperature in a cool place, away from light and heat. Do not store in the refrigerator. Throw away an opened vial after 42 days, even if there is still insulin in it. Injection routeThrow away Continue reading >>
What is the treatment for diabetes mellitus?
Go to: Introduction The use of insulin is a mainstay of treatment for all individuals with type 1 diabetes mellitus (T1DM) and for many individuals with type 2 diabetes mellitus (T2DM). In T1DM, basal insulin in combination with rapid-acting mealtime insulin provides a close but imperfect substitute for endogenous physiologic insulin production. T2DM is characterized by insulin resistance and progressive beta-cell dysfunction. Obesity adds to inherent insulin resistance in T2DM and may be an independent cause of insulin resistance in T1DM. As body mass index (BMI) increases, the rate of diabetes increases, reaching >25% among morbidly obese individuals (BMI >40).1 As insulin resistance increases and insulin secretion declines, increasing doses of insulin may be required to maintain even near euglycemia. Insulin may be the desired therapy in individuals with T2DM with critical beta-cell failure with significant glucotoxicity, intolerance to or failure of oral anti-hyperglycemic therapy, or patient preference. Insulin treatment is generally initiated at weight-based doses, and individuals with high insulin resistance can require doses of insulin as high as 2 units/kg or greater. As the dose of insulin increases, the volume of insulin injected subcutaneously increases. This can result in unpredictable absorption, increased pain, discomfort, and leakage. The most commonly prescribed insulins are referred to as “U100” insulin in which 100 units of insulin are suspended or dissolved in 1 mL of liquid. The U100 basal insulins include neutral protamine Hagedorn (NPH), glargine, degludec, and detemir, as well as short-acting human regular insulin and short-acting insulin analogs (such as lispro, aspart, and glulisine). Only Humulin-R U500 (U-500R) has provided basal insulin Continue reading >>
What is concentrated insulin?
A A A Medications and Drugs Brand Names: Humulin R (Concentrated) Generic Name: insulin regular, concentrated (U-500) (Pronunciation: IN soo lin) What is the most important information I should know about concentrated insulin (Humulin R (Concentrated))? What should I discuss with my healthcare provider before using concentrated insulin (Humulin R (Concentrated))? What is concentrated insulin (Humulin R (Concentrated))? Concentrated insulin is a man-made form of a hormone that is produced in the body. It works by lowering levels of glucose (sugar) in the blood. Concentrated insulin (U-500) is a long-acting form of insulin that is different from other forms that are made from animal insulin. Concentrated insulin is used to treat type 1 (insulin-dependent) diabetes in people with significant daily insulin needs (more than 200 units per day). Concentrated insulin may also be used for purposes other than those listed in this medication guide. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Tell your doctor if you have any pain, redness, swelling, or skin changes where the insulin was injected. Low blood sugar is the most common side effect of concentrated insulin. Symptoms of low blood sugar may include headache, nausea, hunger, confusion, drowsiness, weakness, dizziness, blurred vision, fast heartbeat, sweating, tremor, trouble concentrating, confusion, seizure (convulsions), or death. Watch for signs of low blood sugar. This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088. What is the most important information I should know about concen Continue reading >>
Humulin R U-500 (Concentrated) Prices
The cost for Humulin R U-500 (Concentrated) subcutaneous solution (human recombinant 500 units/mL) is around $1,562 for a supply of 20 milliliters, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
Drugs.com Printable Discount Card
The free Drugs.com Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions.
Humulin R U-500 (Concentrated) Coupons and Rebates
Humulin R U-500 (Concentrated) offers may be in the form of a printable coupon, rebate, savings card, trial offer, or free samples. Some offers may be printed right from a website, others require registration, completing a questionnaire, or obtaining a sample from the doctor's office.
Patient Assistance Programs for Humulin R U-500 (Concentrated)
Patient assistance programs (PAPs) are usually sponsored by pharmaceutical companies and provide free or discounted medicines to low income or uninsured and under-insured people who meet specific guidelines. Eligibility requirements vary for each program.
Humulin R U-500 KwikPen Prices
The cost for Humulin R U-500 KwikPen subcutaneous solution (human recombinant 500 units/mL) is around $609 for a supply of 6 milliliters, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
Drugs.com Printable Discount Card
The free Drugs.com Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions.
Humulin R U-500 KwikPen Coupons and Rebates
Humulin R U-500 KwikPen offers may be in the form of a printable coupon, rebate, savings card, trial offer, or free samples. Some offers may be printed right from a website, others require registration, completing a questionnaire, or obtaining a sample from the doctor's office.
Patient Assistance Programs for Humulin R U-500 KwikPen
Patient assistance programs (PAPs) are usually sponsored by pharmaceutical companies and provide free or discounted medicines to low income or uninsured and under-insured people who meet specific guidelines. Eligibility requirements vary for each program.
Important Note
The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.
Uses
Insulin is used to treat diabetes mellitus. Controlling high blood sugar helps prevent heart disease, strokes, kidney disease, circulation problems, and blindness.
How To Use
Insulin must be injected. Learn the proper way to inject insulin. Check the dose carefully. Clean the injection site with rubbing alcohol. Change the injection site daily to prevent skin bulges or pockets. Do not inject cold insulin. The insulin container you are currently using can be kept at room temperature.
Side Effects
Insulin may cause minor and usually temporary side effects such as rash, irritation or redness at the injection site. To help prevent hypoglycemia, eat meals on a regular schedule. Too much insulin can cause low blood sugar (hypoglycemia).
Precautions
Tell your doctor if you have had allergic reactions, especially to beef, pork or human insulin and of your medical history especially of: thyroid problems, kidney or liver disease, any current infection. Dosage adjustments may be required when you become ill, are under stress, or when quitting smoking.
Drug Interactions
Before you use insulin, tell your doctor of all prescription and nonprescription drugs you are taking especially: beta-blockers (acebutolol, atenolol, betaxolol, esmolol, metoprolol, carteolol, nadolol, penbutolol, pindolol, propranolol, timolol, bisoprolol), fenfluramine, MAO inhibitors (e.g., furazolidone, linezolid, phenelzine, selegiline, tranylcypromine), salicylates (aspirin-like compounds), dexfenfluramine, steroids (e.g., prednisone, hydrocortisone), birth control pills, sulfa antibiotics, water pills, ACE inhibitors, octreotide, isoniazid, niacin, estrogens, cold and allergy drugs, drugs that contain alcohol or sugar.
Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include unconsciousness, seizures, muscle weakness, slow or shallow breathing, headache, vomiting, fever, diarrhea, shakiness, nervousness, fast heartbeat, hunger, or sweating.
