What is Invokana used to treat?
to reduce the risk of end-stage kidney disease (ESKD), worsening of kidney function, cardiovascular death, and hospitalization for heart failure in adults with type 2 diabetes mellitus and diabetic kidney disease (nephropathy) with a certain amount of protein in the urine INVOKANA® is not for people with type 1 diabetes.
How much does Invokana® cost?
Eligible commercial patients pay $0 per month for INVOKANA®, subject to monthly program benefit limits. There is no limit to this benefit for the first month of treatment, and then $200 limit for each month thereafter. There is a $3,000 maximum program benefit per calendar year.
When to increase the dose of Invokana® 100 mg?
For patients with eGFR <60 mL/min/1.73 m2, if an inducer of UGTs is co-administered with INVOKANA®, increase the dose to 200 mg (taken as two 100 mg tablets) once daily in patients currently tolerating INVOKANA® 100 mg. Consider adding another antihyperglycemic agent in patients who require additional glycemic control.
Is Invokana safe for adults with Type 2 diabetes?
INVOKANA ® is not used to lower blood sugar (glucose) in adults with type 2 diabetes with severe kidney problems. It is not known if INVOKANA ® is safe and effective in children under 18 years of age. Amputations. INVOKANA® may increase your risk of lower-limb amputations.
How do you get Invokana?
Or you may register at Invokana.com or by calling 877-INVOKANA (877-468-6526). The following programs are not affiliated with Janssen. Be sure to contact the programs directly to get details on eligibility and application requirements, and to see if they have funding available to help you.
How do you save on Invokana?
Patients can text “SAVINGS” to 48798 (message and data rates may apply*) or use Express Enrollment at MyJanssenCarePath.com/Express to receive an electronic card that can be saved to their mobile wallet, or they can register for the Savings Program and sign up for ongoing support at INVOKANA.com.
Who is the manufacturer of Invokana?
RARITAN, N.J., March 29, 2013 – Janssen Pharmaceuticals, Inc. announced today the U.S. Food and Drug Administration (FDA) has approved INVOKANA™ (canagliflozin) for the treatment of adults with type 2 diabetes.
Is there an alternative to Invokana?
Multiple brand-name drugs are on the market that are similar to Invokana. Just like Invokana, Farxiga and Jardiance are two SGLT2 inhibitors used to control blood sugar in those with type 2 diabetes. Both of these have been shown to lower A1C levels by as much as 1%, but they are expensive.
When will Invokana become generic?
Invokana was eligible for patent challenges on March 29, 2017. By analyzing the patents and regulatory protections it appears that the earliest date for generic entry will be May 11, 2031.
Why was Invokana taken off the market?
This information is an update to the FDA Drug Safety Communication: FDA confirms increased risk of leg and foot amputations with the diabetes medicine canagliflozin (Invokana, Invokamet, Invokamet XR) issued on May 16, 2017.
Is there a lawsuit against Invokana?
Currently, lawsuits have been filed against the makers of Invokana and other SGLT2 inhibitor manufacturers, claiming that the drugs cause acute interstitial nephritis, chronic kidney disease, end-stage renal disease, and acute kidney injuries.
Does Invokana cause hair loss?
Does Invokana cause hair loss, pancreatitis, or joint pain? No, this isn't likely. Hair loss and joint pain weren't reported in studies of Invokana.
Does Invokana make you tired?
In this pool, INVOKANA was also associated with the adverse reactions of fatigue (1.8%, 2.2%, and 2.0% with comparator, INVOKANA 100 mg, and INVOKANA 300 mg, respectively) and loss of strength or energy (i.e., asthenia) (0.6%, 0.7%, and 1.1% with comparator, INVOKANA 100 mg, and INVOKANA 300 mg, respectively).
What are the dangers of Invokana?
Serious side effectsDehydration (low fluid level), which can cause low blood pressure. ... Hypoglycemia (low blood sugar level). ... Severe allergic reaction.*Amputation of lower limbs.*Diabetic ketoacidosis (increased levels of ketones in your blood or urine).*Fournier's gangrene (severe infection near the genitals).*More items...
What happens when you stop taking Invokana?
Will stopping my Invokana treatment cause any side effects? No, stopping Invokana treatment doesn't cause any side effects. But without treatment, your blood sugar levels may go up. You shouldn't stop taking Invokana unless your doctor recommends it.
Is Invokana safe for kidneys?
30, 2019— “The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that their drug INVOKANA® (Canagliflozin) has been approved by the U.S. Food and Drug Administration (FDA) to reduce the risk of end-stage kidney disease (ESKD) and cardiovascular events in patients with Type 2 diabetes and chronic ...
Is there a generic for Invokamet?
No. Currently, there is no generic equivalent for Invokamet (canagliflozin / metformin) available in the United States.
Which is better Ozempic or Invokana?
Gerti Tashko, M.D. The Lancets, Diabetes and Endocrinology has just published the results of SUSTAIN 8 clinical trial.
Is Farxiga better than Invokana?
Is Farxiga Worse Than Invokana? Farxiga (sold under the brand name Forxiga outside the United States), appears to have all the same adverse side effects as Invokana, however Farxiga has also been found to increase LDL cholesterol (the “bad” cholesterol).
What are the dangers of Invokana?
Serious side effectsDehydration (low fluid level), which can cause low blood pressure. ... Hypoglycemia (low blood sugar level). ... Severe allergic reaction.*Amputation of lower limbs.*Diabetic ketoacidosis (increased levels of ketones in your blood or urine).*Fournier's gangrene (severe infection near the genitals).*More items...
How to unsubscribe from Invokana?
You may unsubscribe from receiving further communications by following the instructions in the messages you receive, by following the unsubscribe link in any e-mail we send , or by calling 1-877-INVOKANA ( 1-877-468-6526 ).
What information is needed to register for Invokamet?
Before you register for the program, it is important that you understand that you will be asked to provide personal information that may include your name, address, phone number, email address, and information related to your prescription medication insurance and treatment. This information is necessary to permit Janssen Pharmaceuticals, Inc., the maker of INVOKANA ®, INVOKAMET ®, and INVOKAMET ® XR, and companies that work with Janssen Pharmaceuticals, Inc., including our affiliates and our service providers, to fulfill your request to register for the Janssen CarePath Savings Program. We may also use the information you give us to learn more about the people who use INVOKANA ®, INVOKAMET ®, and INVOKAMET ® XR, and to improve the information we provide to people who are being treated with INVOKANA ®, INVOKAMET ®, and INVOKAMET ® XR. Janssen Pharmaceuticals, Inc., will not share your information with anyone else except as required by law.
How to use Janssen Carepath card?
When you register, you'll receive a Janssen CarePath Savings Program card. Download and print the card, and present the card at your pharmacy along with a valid prescription. Your eligibility to use this card is dependent upon meeting the program requirements each time you present the card when filling your prescription.
Do I need to register my Janssen Carepath card?
Yes, I have a Janssen CarePath Savings Program card and I need to register it.
Is Janssen Carepath an extension?
Janssen CarePath is in no way an extension of medical treatment provided by healthcare professionals to individual patients. You may discontinue your participation at any time by calling 877-468-6526 . Please read and agree to the Janssen CarePath Savings Program Terms and Conditions.
What to tell your doctor before taking Invokana?
Before taking INVOKANA®, tell your doctor if you:have a history of amputation; have heart disease or are at risk for heart disease; have had blocked or narrowed blood vessels (usually in leg); have damage to the nerves (neuropathy) in your leg; have had diabetic foot ulcers or sores; have kidney problems; have liver problems; have a history of urinary tract infections or problems with urination; are on a low sodium (salt) diet; are going to have surgery (your doctor may stop your INVOKANA®before you have surgery; talk to your doctor if you are having surgery about when to stop taking INVOKANA®and when to start it again); are eating less or there is a change in diet; have or have had pancreas problems; drink alcohol very often (or drink a lot of alcohol in the short-term); or ever had an allergic reaction to INVOKANA®.
Can INVOKANA cause dizziness?
Talk to your doctor about proper foot care. Dehydration. INVOKANA®can cause some people to become dehydrated (the loss of too much body water), which may cause you to feel dizzy, faint, lightheaded, or weak, especially when you stand up (orthostatic hypotension).
Can INVOKANA cause amputation?
IMPORTANT SAFETY INFORMATION . INVOKANA®can cause serious side effects, including: Amputations. INVOKANA®may increase your risk of lower-limb amputations. Amputations mainly involve removal of the toe or part of the foot; however, amputations involving the leg, below and above the knee, have also occurred.
Can INVOKANA harm my baby?
Tell your doctor if you are or plan to become pregnant, are breastfeeding, or plan to breastfeed. INVOKANA®may harm your unborn baby. If you become pregnant while taking INVOKANA®, tell your doctor right away. INVOKANA®may pass into your breast milk and may harm your baby. Do not breastfeed while taking INVOKANA®.
Is Invokana good for diabetics?
INVOKANA®is not for people with type 1 diabetes. It may increase their risk of diabetic ketoacidosis (increased ketones in blood or urine).
What to do if you overdose on a drug?
In the event of an overdose, contact the Poison Control Center and employ the usual supportive measures.
Does Invokana cause renal volume depletion?
Volume Depletion: INVOKANA ® can cause intravascular volume contraction, which may sometimes manifest as symptomatic hypotension or acute transient changes in creatinine. There have been postmarketing reports of acute kidney injury which are likely related to volume depletion, some requiring hospitalizations and dialysis, in patients with type 2 diabetes mellitus receiving SGLT2 inhibitors, including INVOKANA ®. Patients with impaired renal function (eGFR less than 60 mL/min/1.73 m 2 ), elderly patients, or patients on loop diuretics may be at increased risk for volume depletion or hypotension. Before initiating INVOKANA ® in patients with one or more of these characteristics, assess and correct volume status. Monitor for signs and symptoms of volume depletion after initiating therapy.
Is Invokana safe for pregnant women?
Pregnancy: INVOKANA ® is not recommended in pregnant women, especially during the second and third trimesters.
Does Invokana cause genital mycotic infections?
Genital Mycotic Infections: INVOKANA ® increases risk of genital mycotic infections, especially in uncircumcised males or patients with prior infections. Monitor and treat appropriately.
Is Invokana safe for renal impairment?
Renal Impairment: The efficacy and safety of INVOKANA ® for glycemic control were evaluated in a trial that included patients with moderate renal impairment (eGFR 30 to <50 mL/min/1.73 m 2 ). These patients had less overall glycemic efficacy, and patients treated with 300 mg per day had increases in serum potassium, which were transient and similar by the end of the study. Patients with renal impairment using INVOKANA ® for glycemic control may be more likely to experience hypotension and may be at a higher risk for acute kidney injury. INVOKANA ® is contraindicated in patients with ESKD on dialysis.
How to contact Janssen Carepath Care Coordinator?
Support for patients using government-funded healthcare programs or patients without insurance coverage: Call a Janssen CarePath Care Coordinator at 877-CarePath (877-227-3728) , or visit. JanssenPrescriptionAssistance.com for more information on affordability programs that may be available. Learn more.
What is JJPAF in healthcare?
(JJPAF) is an independent, nonprofit organization that is committed to helping eligible patients without insurance coverage receive prescription products donated by Johnson & Johnson operating companies. To see if they might qualify for assistance, please have your patient contact a JJPAF program specialist at 800-652-6227 (Monday-Friday, 9:00 AM to 6:00 PM ET) or visit the foundation website at JJPAF.org .
How to report INVOKANA side effects?
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects to Janssen Scientific Affairs, LLC at 1-800-526-7736. Please read full Product Information and Medication Guide for INVOKANA®.
What to tell your doctor before taking Invokana?
Before taking INVOKANA®, tell your doctor if you: have a history of amputation; have heart disease or are at risk for heart disease; have had blocked or narrowed blood vessels (usually in leg); have damage to the nerves (neuropathy) in your leg; have had diabetic foot ulcers or sores; have kidney problems; have liver problems; have a history of urinary tract infections or problems with urination; are on a low sodium (salt) diet; are going to have surgery (your doctor may stop your INVOKANA ® before you have surgery; talk to your doctor if you are having surgery about when to stop taking INVOKANA ® and when to start it again); are eating less or there is a change in diet; have or have had pancreas problems; drink alcohol very often (or drink a lot of alcohol in the short-term); or ever had an allergic reaction to INVOKANA ® .
Is Invokana safe for kidneys?
INVOKANA ® is not used to lower blood sugar (glucose) in adults with type 2 diabetes with severe kidney problems. It is not known if INVOKANA ® is safe and effective in children under 18 years of age. Amputations.
Can INVOKANA cause a burning sensation?
Serious Urinary Tract Infections: may lead to hospitalization and have happened in people taking INVOKANA ®. Tell your doctor if you have any signs or symptoms of a urinary tract infection such as: burning feeling while urinating, need to urinate often or right away, pain in the lower part of your stomach (pelvis), or blood in the urine. Some people may also have fever, back pain, nausea, or vomiting
Can INVOKANA harm my baby?
Tell your doctor if you are or plan to become pregnant, are breastfeeding, or plan to breastfeed. INVOKANA ® may harm your unborn baby. If you become pregnant while taking INVOKANA ®, tell your doctor right away. INVOKANA ® may pass into your breast milk and may harm your baby.
Can INVOKANA cause dizziness?
INVOKANA® can cause some people to become dehydrated (the loss of too much body water), which may cause you to feel dizzy, faint, lightheaded, or weak, especially when you stand up (orthostatic hypotension). There have been reports of sudden worsening of kidney function in people with type 2 diabetes who are taking INVOKANA®.
Can INVOKANA cause low blood sugar?
Low blood sugar (hypoglycemia). If you take INVOKANA ® with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin, your risk of getting low blood sugar is higher.
What is The Patient Assistance Program?
The Johnson & Johnson Patient Assistance Foundation, Inc. (JJPAF) is an independent, non-profit organization that is committed to helping eligible patients without insurance coverage receive prescription products donated by Johnson & Johnson operating companies.
Program Update
Patients may now choose the option of electronic income verification. Instead of submitting a copy of their Federal tax return, they can simply check a box on the updated application form.
