The KYPROLIS ® Patient Support program can help you feel more in control and confident about taking the next step. The Patient Support program is designed to provide you with important information about KYPROLIS ®, including educational materials that can help support you through your treatment journey.
Full Answer
What are the FDA approved uses of Kyprolis?
Approved Uses. KYPROLIS ® (carfilzomib) is a prescription medication used to treat patients with relapsed or refractory multiple myeloma who have received one to three previous treatments for multiple myeloma. KYPROLIS is approved for use in combination with dexamethasone or with lenalidomide plus dexamethasone,...
What is Kyprolis (carfilzomib)?
Kyprolis Prices, Coupons and Patient Assistance Programs. Kyprolis (carfilzomib) is a member of the proteasome inhibitors drug class and is commonly used for Multiple Myeloma.
How effective are Kyprolis® combinations for multiple myeloma?
In clinical studies of patients with relapsed or refractory multiple myeloma, four KYPROLIS® combinations kept the disease from getting worse and helped patients reach at least a complete response better than comparators:
What are the side effects of Kyprolis?
Pulmonary hypertension (high blood pressure in the lungs): There have been reports of pulmonary hypertension in patients receiving KYPROLIS. Lung complications: Shortness of breath was reported in patients receiving KYPROLIS. Your lung function should be closely monitored during treatment.
Is kyprolis a chemo or immunotherapy?
Kyprolis (carfilzomib) is a type of chemotherapy drug and a second-generation proteasome inhibitor. Kyprolis is used to treat multiple myeloma, which is a type of hematological malignancy, or blood cancer, that affects plasma cells.
Is kyprolis better than Velcade?
"These results confirm the superiority of KYPROLIS over Velcade in relapsed or refractory multiple myeloma patients," said Sean E. Harper , M.D., executive vice president of Research and Development at Amgen . "A survival benefit has rarely been demonstrated in relapsed or refractory multiple myeloma.
What are the side effects of kyprolis?
Common side effects of Kyprolis are:fatigue.low blood cell count and blood platelet levels.shortness of breath.diarrhea.constipation.nausea.fever.swelling of the extremities.More items...
What is Amgen assist 360?
Amgen Assist 360™ can refer patients to independent nonprofit patient assistance programs that may be able to help them afford the co-pay costs for their prescribed medicine.
Which is better bortezomib or carfilzomib?
The first pre-specified interim analysis showed that patients in the carfilzomib group had higher rates of deeper responses, which translated into significantly longer progression-free survival than those who received bortezomib (median progression-free survival 18·7 months [95% CI 15·6–not estimable] vs 9·4 months [8· ...
Is carfilzomib better than bortezomib?
In the phase 3 ENDEAVOR trial, carfilzomib (56 mg/m2) and dexamethasone (Kd56) demonstrated a clinically and statistically significant improvement compared with bortezomib and dexamethasone (Vd) in progression-free survival (PFS; primary end point; median, 18.7 vs 9.4 months; hazard ratio [HR], 0.53; 95% confidence ...
How long can you take kyprolis?
You'll likely receive Kyprolis for 3 weeks, followed by 1 week without any infusions. But depending on how long you've been using Kyprolis, you may receive infusions every other week. Your doctor will explain how often you'll receive Kyprolis infusions and how long your treatment may last.
How fast does myeloma progress?
The risk of myeloma progressing is highest in the first 5 years after diagnosis. About 50 out of 100 people (50%) with smouldering myeloma develop symptoms and need treatment within the first 5 years. However, after 5 years the risk decreases and some people never develop symptoms or need treatment.
What is the best treatment for multiple myeloma?
Corticosteroids help destroy myeloma cells and make chemotherapy more effective. The most common types used to treat myeloma are dexamethasone and prednisolone. Steroids are taken by mouth after eating.
Does Amgen have a patient assistance program?
Through patient assistance programs, expanded access to investigational therapies, donations, and other programs, we've developed support programs for eligible patients around the world as they seek to obtain the medications they need.
What is Amgen first step program?
The Amgen FIRST STEP™ Program is here to help eligible commercially insured patients pay for their out-of-pocket prescription costs, including deductible, co-insurance, and co-payment.
How can I get Prolia for free?
Amgen Safety Net Foundation is an independent, nonprofit patient assistance program that provides Prolia® at no cost to qualifying patients who have a financial need and who are uninsured or have insurance that excludes Prolia®.
Do you lose your hair with kyprolis?
Hair loss hasn't been reported as a side effect of Kyprolis. With other cancer treatments, such as chemotherapy (traditional drugs used to treat cancer), hair loss is often a side effect.
How effective is kyprolis?
Results from an early study in newly diagnosed patients suggest that the combination of Kyprolis, Revlimid, and low-dose dexamethasone is highly effective, with 98% of patients responding to treatment and 42% achieving a stringent complete response.
Does kyprolis cause shortness of breath?
Shortness of breath is one of the more common side effects of Kyprolis. You may feel that you're having trouble breathing or that you can't catch your breath even while at rest. This side effect was usually mild in studies, but in some cases, it was severe.
How often is kyprolis given?
KYPROLIS is administered intravenously over 2 to 10 minutes, on two consecutive days, each week for three weeks (Days 1, 2, 8, 9, 15, and 16), followed by a 12-day rest period (Days 17 to 28). Each 28-day period is considered one treatment cycle (Table 1).
Billing Professionals Resource Center
From access and reimbursement to webinars and useful links, our Billing Professionals Resource Center has the tools to help you stay informed.
For patients with government insurance like Medicare
We provide referrals to independent nonprofit patient assistance programs that may be able to help them afford the co-pay cost of their medicine.**
For uninsured patients
Amgen Safety Net Foundation is a nonprofit patient assistance program sponsored by Amgen that helps qualifying patients access Amgen medicines at no cost.
How to contact KYPROLIS?
KYPROLIS ® Field Representatives are here to answer any questions you may have or to schedule a visit. To report an adverse event, please call 1-800-77-AMGEN (1-800-772-6436). By clicking "Submit,” you agree to disclose your personal information to Amgen and to be contacted by Amgen and their agents in the future regarding products, services, ...
What is the best combination for kyprolis?
KYPROLIS ® (carfilzomib) is indicated in combination with dexamethasone or with lenalidomide plus dexamethasone or with daratumumab and dexamethasone for the treatment of adult patients with relapsed or refractory multiple myeloma who have received one to three lines of therapy.
What is TTP/HUS?
Cases of thrombotic microangiopathy, including thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS), including fatal outcome, have occurred. Monitor for signs and symptoms of TTP/HUS. Discontinue if diagnosis is suspected. If the diagnosis of TTP/HUS is excluded, KYPROLIS may be restarted. The safety of reinitiating KYPROLIS is not known.
Is Kyprolis a single agent?
KYPROLIS ® is indicated as a single agent for the treatment of adult patients with relapsed or refractory multiple myeloma who have received one or more lines of therapy.
Does Kyprolis cause liver failure?
Cases of hepatic failure, including fatal cases, have occurred. KYPROLIS can cause increased serum transaminases. Monitor liver enzymes regularly regardless of baseline values. Reduce or withhold dose as appropriate.
Can you restart Kyprolis if you have hypertension?
Control hypertension prior to starting KYPROLIS. Monitor blood pressure regularly in all patients. If hypertension cannot be adequately controlled, with hold KYPROLIS and evaluate. Consider whether to restart based on a benefit/risk assessment.
Is uric acid lowering medicine safe for TLS?
Cases of Tumor Lysis Syndrome (TLS), including fatal outcomes, have occurred. Patients with a high tumor burden should be considered at greater risk for TLS. Adequate hydration is required prior to each dose in Cycle 1, and in subsequent cycles as needed. Consider uric acid lowering drugs in patients at risk for TLS. Monitor for evidence of TLS during treatment and manage promptly, and withhold until resolved.
What is the Kyprolis Amgen first step program?
Kyprolis Amgen First Step Program: Eligible commercially insured patients may save on their out-of-pocket medication costs; for additional information contact the program at 888-427-7478.
Who is the rebate number for Kyprolis Amgen?
Kyprolis Amgen First Step Program Rebate: Eligible commercially insured patients who have already paid for treatment may request a rebate check; for additional information contact the program at 888-657-8371.
Does Kyprolis offer coupons?
Kyprolis Coupons and Rebates. Kyprolis offers may be in the form of a printable coupon, rebate, savings card, trial offer, or free samples. Some offers may be printed right from a website, others require registration, completing a questionnaire, or obtaining a sample from the doctor's office.
Do you have to be a US citizen to be a patient?
The patient must also be a US citizen.
Is Kyprolis a generic?
A generic version of Kyprolis has been approved by the FDA . However we either do not have pricing information for it, or it is not commercially available. More info: generic Kyprolis availability. This Kyprolis price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
If you have commercial insurance
The Amgen FIRST STEP™ Program can help eligible commercially insured patients meet their deductible, co-insurance, or co-payment. ‡
If you have government insurance like Medicare
Amgen Assist 360™ can refer patients to independent nonprofit patient assistance programs that may be able to help them afford the co-pay costs for their prescribed medicine. †
For uninsured patients
Amgen Safety Net Foundation is a nonprofit patient assistance program sponsored by Amgen that helps qualifying patients access Amgen medicines at no cost.
What is a kyprolis?
KYPROLIS ® (carfilzomib) is a prescription medication used to treat adult patients with relapsed or refractory multiple myeloma who have received one to three previous treatments for multiple myeloma.
How long does it take to live with Kyprolis?
KYPROLIS® given twice a week with DARZALEX ® (daratumumab) and dexamethasone kept the disease from getting worse longer than KYPROLIS ® and dexamethasone alone. With a median follow-up of nearly 28 months, the median progression-free survival (the length of time from the start of treatment until half of the patients have experienced worsening disease or death) for patients who received KYPROLIS ®, DARZALEX ®, and dexamethasone was 28.6 months vs 15.2 months for KYPROLIS ® and dexamethasone alone. In an earlier analysis with a median follow-up of ~17 months, more patients reached a complete response when they received KYPROLIS ® given with DARZALEX ® and dexamethasone vs KYPROLIS ® and dexamethasone alone (28% vs 10%).
How long does it take for a kyprolis to cause chest pain?
These symptoms can occur immediately following infusion or up to 24 hours after administration of KYPROLIS. If you experience any of these symptoms, contact your doctor immediately.
Can you take Kyprolis with Daratumumab?
KYPROLIS is approved for use in combination with daratumumab plus dexamethasone, dexamethasone or with lenalidomide plus dexamethasone, which are other medicines used to treat multiple myeloma. See More.
Can you take melphalan with kyprolis?
KYPROLIS should not be combined with melphalan and prednisone: Newly diagnosed transplant ineligible multiple myeloma patients have shown an increased risk of serious and fatal side effects when using KYPROLIS in combination with melphalan and prednisone.
Where to report side effects of prescription drugs?
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call
Can you get blood clots with Kyprolis?
Blood clots: There have been reports of blood clots in patients receiving KYPROLIS. If you are at high risk for blood clots, your doctor can recommend ways to lower the risk.
What is Kyprolis used for?
Kyprolis is a proteasome inhibitor that is used to treat people with relapsed or refractory multiple myeloma. It works by blocking a cell’s proteasomes, which causes a build-up of proteins inside the cells resulting in the death of myeloma cells.
Can Prescription Hope Help Me Obtain My Other Medications?
Prescription Hope works directly with over 180 U.S. based pharmaceutical manufacturers patient assistance programs to obtain over 1,500 FDA-approved prescription medications. Visit our website to see our full list of medications and fill out an application.
Is Prescription Hope A Kyprolis Coupon Card, Generic, Or Insurance Product?
Prescription Hope is not a Kyprolis coupon card or insurance policy. Our program is also not a Kyprolis Generic. Prescription Hope is a national advocacy program that works with any coverage you may already have. Although Prescription Hope is not a Kyprolis coupon, individuals looking for a Kyprolis coupon can find more savings through Prescription Hope!
Can Prescription Hope Get My Kyprolis If I Have Health Insurance Coverage?
Because Prescription Hope is not a health insurance plan, our program works alongside any coverage you may currently have to obtain your Kyprolis medication at an affordable price. Our national advocacy program does not have medication tiers, copays, or deductibles.
Do I Qualify For Kyprolis Patient Assistance With Prescription Hope?
Prescription Hope works with thousands of Americans every month, obtaining prescription medications on their behalf for the set price of $50.00 per month per medication.
What is the treatment for renal cell carcinoma?
LENVIMA is used along with another medicine called everolimus to treat advanced renal cell carcinoma (RCC), a type of kidney cancer, after one course of treatment with another anti-cancer medicine.
How to report lenviga side effects?
These are not all the possible side effects of LENVIMA. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088 or visit www.fda.gov/medwatch. For more information about LENVIMA, please see full Prescribing Information .
Can lenviga cause kidney failure?
kidney problems: Kidney failure, which can lead to death, has happened with LENVIMA treatment. Your healthcare provider should do regular blood tests to check your kidneys. increased protein in your urine (proteinuria): Proteinuria is a common side effect of LENVIMA and can be serious.
If you have commercial insurance
The Amgen FIRST STEP™ Program can help eligible commercially insured patients meet their deductible, co-insurance, or co-payment. ‡
If you have government insurance like Medicare
Amgen Assist 360™ can refer patients to independent nonprofit patient assistance programs that may be able to help them afford the co-pay costs for their prescribed medicine. †
For uninsured patients
Amgen Safety Net Foundation is a nonprofit patient assistance program sponsored by Amgen that helps qualifying patients access Amgen medicines at no cost.
