Patient Assistance Program We research financial assistance opportunities for patients with no or insufficient prescription insurance coverage or insufficient resources to pay for LONSURF. Eligible patients may receive LONSURF at no cost based on assistance, financial, and medical criteria
Full Answer
Is there a patient assistance program for those unable to afford Lonsurf?
Patient Assistance Program for those unable to afford LONSURF We may be able to provide LONSURF to you free of charge if you have: • No prescription insurance coverage • Insuffi cient prescription insurance coverage • Insuffi cient fi nancial resources Pharmacy coordination
How do I contact Lonsurf patient support?
Call 1-844-TAIHO-4U (1-844-824-4648) Or visit TaihoPatientSupport.com You can also learn more about our patient support program at LONSURF.com/assistance 11 Important Safety Information LONSURF (trifl uridine and tipiracil) may cause serious side effects, including: • counts. blood ow L
How can I get help with Lonsurf out-of-pocket expenses?
If you are commercially insured, you may be eligible to receive a Co-pay Card for help with your out-of-pocket expenses for LONSURF.* Ask your healthcare provider or pharmacy for the Taiho Oncology Patient Support Co-pay Card if you have commercial insurance.
What is the life expectancy of someone with Lonsurf?
In a clinical trial, half of the patients treated with LONSURF were still alive at 7.1 months and half of the patients who received placebo were still alive at 5.3 months. Worsening of the disease or death occurred in 88% of patients treated with LONSURF and 94% of patients who received placebo.
How long do people live on LONSURF?
In a clinical trial, half of the patients with metastatic stomach cancer treated with LONSURF were still alive at 5.7 months and half of the patients who received placebo were still alive at 3.6 months.
Do you lose your hair with LONSURF?
skin problems such as a rash, itchy or flaky skin or flushing – talk to your team about any changes to your skin. tummy pain. low levels of albumin in your body that can cause swelling and weakness. hair loss – this is usually temporary and grows back after treatment finishes.
Does LONSURF shrink tumors?
Tipiracil slows down the body's ability to break down trifluridine, which allows it to stay in the body longer and affect more colon cancer cells. Goals of therapy: Trifluridine and tipiracil is taken to shrink colon tumors or decrease symptoms of colon cancer and is not commonly given with the goal of cure.
Do you take LONSURF with food?
LONSURF® (trifluridine and tipiracil) tablets are: A tablet you swallow twice a day with food- the type of food does not matter. A tablet you swallow whole. Do not retake doses of LONSURF that are vomited or missed and continue with the next scheduled dose.
What is the success rate of LONSURF?
At 12 months, treatment with Lonsurf and Avastin induced a progression-free survival rate of 40% versus 30% with the Xeloda-based treatment.
Does LONSURF make you tired?
The most common side effects with LONSURF include tiredness (fatigue, weakness), nausea, decreased appetite, diarrhea, vomiting, abdominal pain, and fever. Tell your doctor if you have nausea, vomiting, or diarrhea that is severe or that does not go away. These are not all of the possible side effects of LONSURF.
What is the success rate of Avastin?
Results : Of 133 patients, 106 (80%) achieved treatment stability on Avastin. 70 patients (53%) were stable on injections every 8 weeks or longer, and 36 patients (27%) required injections more frequently than every 8 weeks.
What are the side effects of LONSURF?
The most common side effects with LONSURF include tiredness (fatigue, weakness), nausea, decreased appetite, diarrhea, vomiting, abdominal pain, and fever. Tell your doctor if you have nausea, vomiting, or diarrhea that is severe or that does not go away. These are not all of the possible side effects of LONSURF.
Is LONSURF better than stivarga?
These agents were tested in very similar settings, but they have never been compared head-to-head. Stivarga was compared with placebo in a large study and it showed superiority to placebo in all parameters. Lonsurf was also compared with placebo and also showed an improvement in all efficacy parameters.
What company makes LONSURF?
LONSURF (trifluridine/tipiracil), discovered and developed by Taiho Pharmaceutical Co., Ltd., is an oral anticancer drug, which utilizes the combination of trifluridine (FTD) and tipiracil (TPI), whose dual mechanism of action is designed to maintain clinical activity and differs from conventional fluoropyrimidines.
How do you dispose of LONSURF?
If you store LONSURF outside of the original bottle, throw away (dispose of) any unused LONSURF tablets after 30 days. Talk to your healthcare provider about how to safely dispose of LONSURF. Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet.
How is LONSURF administered?
The recommended starting dose of Lonsurf in adults is 35 mg/m2/dose administered orally twice daily on Days 1 to 5 and Days 8 to 12 of each 28-day cycle as long as benefit is observed or until unacceptable toxicity occurs (see section 4.4). The dose is calculated according to body surface area (BSA) (see Table 1).
What is the black bulb at the end of hair?
When you pull out your hair "by the root," you may observe a transparent swelling called the "bulb." The area above the bulb usually seen on a plucked hair is the root sheath, the growing area of a hair. The size of the hair bulb on a plucked hair varies with the phase of growth the hair was in.
Does hair grow back after falling out from roots?
Pulling out hair by your root may damage your follicle temporarily, but a new bulb will eventually form, and new hair will grow again through that follicle.
What is the white bulb at the end of hair?
keratinWhat is the White Bulb on Hair? The small bulb at the end of a shed hair is a lump of keratin, a protein that makes up your hair, skin and nails. If you examine your shed hairs, you may notice that some have white bulbs, while others have bulbs that match your natural hair color.
What you can do to prevent hair fall?
Ways to stop hair lossEat extra protein. You may not be getting enough protein each day and that can affect your hair growth. ... Take vitamins. ... Follow the Mediterranean diet. ... Use over-the-counter hair loss medication. ... Try low-level laser light therapy. ... Maintain good hair and scalp care. ... Can hair loss be reversed?
What is cancer care?
CancerCareis a leading national organization providing free, professional support services and information to help people manage the emotional, practical, and fi nancial challenges of cancer. Comprehensive services include counseling and support groups over the phone, online, and in-person, educational workshops, publications, and fi nancial and co-payment assistance. All services are provided by oncology social workers and world-leading cancer experts, free of charge. Learn more at cancercare.org
Is lonsurf safe for children?
LONSURF®(trifl uridine and tipiracil) is a prescription medicine used to treat people with colon or rectal cancer that has spread to other parts of the body and who have been previously treated with or cannot receive certain chemotherapy medicines. It is not known if LONSURF is safe and effective in children. In a clinical trial, half of the patients treated with LONSURF were still alive at 7.1 months and half of the patients who received placebo were still alive at 5.3 months. Worsening of the disease or death occurred in 88% of patients treated with LONSURF and 94% of patients who received placebo.
Does lonsufrf cause nausea?
with LONSURF include tiredness, nausea, decreased appetite, diarrhea, vomiting, abdominal pain, and fever. Tell your doctor if you have nausea, vomiting, or diarrhea that is severe or that does not go away. These are not all of the possible side effects of LONSURF. For more information, ask your healthcare provider. Call your doctor for medical advice about side effects.
What is a lonsurf?
LONSURF is a prescription medicine used to treat adults with
What are the symptoms of a lonsuf?
Tell your healthcare provider right away if you get any of the following signs and symptoms of infection during treatment with LONSURF: fever, chills, or body aches.
What happens if you take lonsuf?
LONSURF can cause a decrease in your white blood cells, red blood cells, and platelets. Low white blood cells can make you more likely to get serious infections that could lead to death. Your healthcare provider should do blood tests before you receive LONSURF, at day 15 during treatment with LONSURF, and as needed to check your blood cell counts. Your healthcare provider may lower your dose of LONSURF or stop LONSURF if you have low white blood cell or platelet counts
Where to fill out patient enrollment form?
Fill out a Patient Enrollment Form at your doctor's office with your doctor, nurse, or support staff. The office can then fax the form to 1‑844‑287‑2559
Does lonsufr cause nausea?
Tell your doctor if you have nausea, vomiting, or diarrhea that is severe or that does not go away. These are not all of the possible side effects of LONSURF.
Can a low blood count cause a death?
LONSURF can cause a decrease in your white blood cells, red blood cells, and platelets. Low white blood cells can make you more likely to get serious infections that could lead to death.
Can a lonsufr hurt a baby?
Are pregnant or plan to become pregnant. LONSURF can harm your unborn baby.
What is a lonsuf?
LONSURF is indicated for the treatment of adult patients with metastatic gastric or gastroesophageal junction adenocarcinoma previously treated with at least two prior lines of chemotherapy that included a fluoropyrimidine, a platinum, either a taxane or irinotecan, and if appropriate, HER2/neu‑targetedtherapy.
What is the molar ratio of Lonsurf?
LONSURF®(trifluridine and tipiracil) tablets consist of a thymidine‑based nucleoside analog, trifluridine, and the thymidine phosphorylase inhibitor, tipiracil, at a molar ratio 1:0.5 (weight ratio, 1:0.471). Inclusion of tipiracil increases trifluridine exposure by inhibiting its metabolism by thymidine phosphorylase.
Can lonsurf harm the fetus?
Embryo‑Fetal Toxicity:LONSURF can cause fetal harm when administered to a pregnant woman. Advise pregnant women of the potential risk to the fetus. Advise females of reproductive potential to use effective contraception during treatment and for at least 6 months after the final dose.
Can you breastfeed with lonsufrf?
Because of the potential for serious adverse reactions in breast‑fed infants, advise women not to breastfeed during treatment with LONSURF and for 1 day following the final dose.
What is a lonsuf?
LONSURF is indicated for the treatment of adult patients with metastatic gastric or gastroesophageal junction adenocarcinoma previously treated with at least two prior lines of chemotherapy that included a fluoropyrimidine, a platinum, either a taxane or irinotecan, and if appropriate, HER2/neu‑targeted therapy.
Can you breastfeed with lonsufrf?
There are no data to assess the effects of LONSURF or its metabolites on the breast‑fed infant or the effects on milk production. Because of the potential for serious adverse reactions in breast‑fed infants, advise women not to breastfeed during treatment with LONSURF and for 1 day following the final dose.
What is a lonsurf?
Lonsurf (tipiracil/trifluridine) is a member of the antineoplastic combinations drug class and is commonly used for Colorectal Cancer, and Gastric Cancer.
How much does a free drug card save?
The free Drugs.com Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions.
Is Lonsurf a generic?
Lonsurf is available as a brand name drug only, a generic version is not yet available. For more information, read about generic Lonsurf availability . This Lonsurf price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
How often can you take lonsurf?
LONSURF®(trifl uridine/tipiracil) tablets are swallowed: • Twice a day with food • The type of food does not matter 15-mg tablet 20-mg tablet LONSURF comes in 2 strengths: 15-mg and 20-mg tablets.* Your healthcare provider may prescribe both strengths for your prescribed dose.
What are the symptoms of a lonsuf?
Tell your healthcare provider right away if you get any of the following signs and symptoms of infection during treatment with LONSURF: fever, chills, or body aches.
How long after Lonsurf can you get pregnant?
You should use effective birth control during and 6 months after the last dose of treatment with LONSURF. Tell your healthcare provider immediately if you become pregnant
What happens if you take lonsuf?
LONSURF can cause a decrease in your white blood cells, red blood cells, and platelets. Low white blood cells can make you more likely to get serious infections that could lead to death. Your healthcare provider should do blood tests before you receive LONSURF, at day 15 during treatment with LONSURF, and as needed to check your blood cell counts. Your healthcare provider may lower your dose of LONSURF or stop LONSURF if you have low white blood cell or platelet counts
How does lonsuf affect blood?
Your healthcare provider should check your blood cell counts before you receive LONSURF, at day 15 during treatment, and as needed. • Low blood counts are common with LONSURF and can sometimes be severe and life-threatening. LONSURF can cause a decrease in your white blood cells, red blood cells, and platelets. Low white blood cells can make you more likely to get serious infections that could lead to death. Your dosage of LONSURF may be reduced or stopped • Tell your healthcare provider right away if you develop any signs of infection such as fever, chills, or body aches
Is lonsuf safe for children?
• a kind of stomach cancer called gastric cancer including cancer of the gastroesophageal junction that has spread to other parts of the body and who have been previously treated or cannot receive certain chemotherapy medications. It is not known if LONSURF is safe and effective in children
Can you take lonsurf with cancer?
With proven results to help patients live longer, LONSURF®(trifl uridine/tipiracil) tablets may allow you to continue your journey with cancer. LONSURF has been proven to: • Allow some patients to live longer • Slow or stop the growth of cancer for a period of time
Warnings and Precautions
- Severe Myelosuppression: LONSURF caused severe and life‑threatening myelosuppression (Grade 3‑4) consisting of neutropenia (38%), anemia (18%), thrombocytopenia (5%), and febrile neutropenia (3%). Two patients (0.2%) died due to neutropenic infection. A total of 12% of LONSURF‑treated patients received granulocyte‑colony stimulating factors. Obtain complete blo…
Use in Specific Populations
- Lactation:It is not known whether LONSURF or its metabolites are present in human milk. There are no data to assess the effects of LONSURF or its metabolites on the breast‑fed infant or the effects on milk production. Because of the potential for serious adverse reactions in breast‑fed infants, advise women not to breastfeed during treatment with LONSURF and for 1 day followin…
Adverse Reactions
- Most Common Adverse Drug Reactions in Patients Treated With LONSURF (≥5%):The most common adverse drug reactions in LONSURF‑treated patients vs placebo‑treated patients with mCRC, respectively, were asthenia/fatigue (52% vs 35%), nausea (48% vs 24%), decreased appetite (39% vs 29%), diarrhea (32% vs 12%), vomiting (28% vs 14%), infections (27% vs 1...