Patient Assistance Program This program provides financial assistance for eligible patients who have insufficient insurance coverage for LONSURF® (trifluridine and tipiracil), including Medicaid, Medicare, or any other public or private program, and who have insufficient financial resources to pay for their treatment.
Full Answer
What are the symptoms of a lonsuf?
What happens if you take lonsuf?
Is lonsurf safe for children?
Does lonsufra have side effects?
Can you get pregnant with lonsufr?
What is the success rate for LONSURF?
At 12 months, treatment with Lonsurf and Avastin induced a progression-free survival rate of 40% versus 30% with the Xeloda-based treatment.
Is LONSURF available in Canada?
We are pleased to announce that PrLONSURF® (trifluridine and tipiracil) is now available in Canada as of January 23, 2018.
How long can you take LONSURF for?
Your doctor will usually prescribe LONSURF for 10 days during the first two weeks and then stop for two weeks.
Is LONSURF a limited distribution drug?
LONSURF is a limited distribution oral cancer medication just approved by the F.D.A. for patients with an advanced form of colorectal cancer who are no longer responding to other therapies.
Is Lonsurf chemotherapy?
Lonsurf is a type of chemotherapy drug. You might have Lonsurf as a treatment for bowel cancer that has spread to other parts of the body. Bowel cancer is cancer that started in the large bowel (colon) or back passage (rectum). Find out about how you have it, possible side effects and other important information.
Is Lonsurf a new drug?
Lonsurf (Trifluridine plus Tipiracil): A New Oral Treatment Approved for Patients with Metastatic Colorectal Cancer - PMC. The . gov means it's official.
Does LONSURF shrink tumors?
Tipiracil slows down the body's ability to break down trifluridine, which allows it to stay in the body longer and affect more colon cancer cells. Goals of therapy: Trifluridine and tipiracil is taken to shrink colon tumors or decrease symptoms of colon cancer and is not commonly given with the goal of cure.
Is LONSURF better than stivarga?
These agents were tested in very similar settings, but they have never been compared head-to-head. Stivarga was compared with placebo in a large study and it showed superiority to placebo in all parameters. Lonsurf was also compared with placebo and also showed an improvement in all efficacy parameters.
Does LONSURF cause stomach pain?
The most common side effects with LONSURF include tiredness (fatigue, weakness), nausea, decreased appetite, diarrhea, vomiting, abdominal pain, and fever.
Which pharmacies can dispense LONSURF?
Our products are available through the following specialty pharmacies: Accredo, Avella, Biologics, CVS/Caremark, Onco360, and Walgreens. It is also available to self-dispensing practices and hospital retail pharmacies through ASD Healthcare, McKesson Specialty Health, McKesson Plasma and Biologics, and Oncology Supply.
What company makes LONSURF?
LONSURF (trifluridine/tipiracil), discovered and developed by Taiho Pharmaceutical Co., Ltd., is an oral anticancer drug, which utilizes the combination of trifluridine (FTD) and tipiracil (TPI), whose dual mechanism of action is designed to maintain clinical activity and differs from conventional fluoropyrimidines.
Is LONSURF generic?
Trifluridine/tipiricil is the generic name for the trade name drug, Lonsurf. In some cases, health care professionals may use the trade name, Lonsurf, when referring to the generic drug name, trifluridine/tipiricil. Drug Type: Trifluridine/tipiricil is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug.
How long is Folfiri effective?
Each cycle of treatment lasts 2 weeks (14 days). Depending on your needs, you may have up to 12 cycles, taking up to 6 months in total.
What type of drug is Lonsurf?
Drug Type: Trifluridine/tipiricil is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug. This medication is classified as an antimetabolite/pyrimidine analog; antimetabolite/thymidine phosphorylase inhibitor (for more detail, see "How Trifluidine/tipiricil Works" below).
How long is a cycle of folfox?
You have FOLFOX chemotherapy as cycles of treatment each lasting 2 weeks. Depending on your needs, you may have up to 12 cycles.
How is Lonsurf administered?
The recommended starting dose of Lonsurf in adults is 35 mg/m2/dose administered orally twice daily on Days 1 to 5 and Days 8 to 12 of each 28-day cycle as long as benefit is observed or until unacceptable toxicity occurs (see section 4.4). The dose is calculated according to body surface area (BSA) (see Table 1).
Lonsurf Prices, Coupons, Copay & Patient Assistance - Drugs.com
Lonsurf Medicare Part D Extra Help Subsidy: Patients who have Medicare Part D coverage may be eligible to apply for the Part D Extra Help Subsidy and once accepted to the program may receive reduced premiums and lower prescription costs; contact the program directly for questions or to sign-up.
Lonsurf Prices, Coupons & Savings Tips - GoodRx
Many programs are available from federal and state governments, non-profits, manufacturers, and other organizations to help you get the drugs you need at a reduced cost. Eligibility is often based on income, insurance or Medicare status, and other factors. You’ll need to apply through each program, either online, over the phone, or with your doctor's help.
(1-844-824-4648) Call 1-844-TAIHO-4U Or visit TaihoPatientSupport
2 Table of contents 3 Introduction Taiho Oncology Patient Support 4 Financial support 5 Personalized nurse support 6 How to enroll Additional tools and resources 7 ®LONSURF (trifl uridine and tipiracil) Starter Kit 8 Video series: Importance of taking your medicine as prescribed 9 Advocacy and support organizations 11 Important Safety Information Please see Important Safety Information on ...
Lonsurf Medicare Coverage and Co-Pay Details - GoodRx
Medicare coverage and pricing details for Lonsurf. Learn more about Medicare prescription drug plans and savings with GoodRx.
LONSURF - Find The Best Price Near You | WellRx
How much does LONSURF cost near you? Find the best LONSURF prices near you now with our cost comparison tool and start saving today.
What is a lonsuf?
LONSURF is indicated for the treatment of adult patients with metastatic gastric or gastroesophageal junction adenocarcinoma previously treated with at least two prior lines of chemotherapy that included a fluoropyrimidine, a platinum, either a taxane or irinotecan, and if appropriate, HER2/neu‑targetedtherapy.
What is the molar ratio of Lonsurf?
LONSURF®(trifluridine and tipiracil) tablets consist of a thymidine‑based nucleoside analog, trifluridine, and the thymidine phosphorylase inhibitor, tipiracil, at a molar ratio 1:0.5 (weight ratio, 1:0.471). Inclusion of tipiracil increases trifluridine exposure by inhibiting its metabolism by thymidine phosphorylase.
Can lonsurf harm the fetus?
Embryo‑Fetal Toxicity:LONSURF can cause fetal harm when administered to a pregnant woman. Advise pregnant women of the potential risk to the fetus. Advise females of reproductive potential to use effective contraception during treatment and for at least 6 months after the final dose.
Can you breastfeed with lonsufrf?
Because of the potential for serious adverse reactions in breast‑fed infants, advise women not to breastfeed during treatment with LONSURF and for 1 day following the final dose.
What is a lonsurf?
Lonsurf (tipiracil/trifluridine) is a member of the antineoplastic combinations drug class and is commonly used for Colorectal Cancer, and Gastric Cancer.
How much does a free drug card save?
The free Drugs.com Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions.
Is Lonsurf a generic?
Lonsurf is available as a brand name drug only, a generic version is not yet available. For more information, read about generic Lonsurf availability . This Lonsurf price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
What is a lonsuf?
LONSURF is indicated for the treatment of adult patients with metastatic gastric or gastroesophageal junction adenocarcinoma previously treated with at least two prior lines of chemotherapy that included a fluoropyrimidine, a platinum, either a taxane or irinotecan, and if appropriate, HER2/neu‑targeted therapy.
Can you breastfeed with lonsufrf?
There are no data to assess the effects of LONSURF or its metabolites on the breast‑fed infant or the effects on milk production. Because of the potential for serious adverse reactions in breast‑fed infants, advise women not to breastfeed during treatment with LONSURF and for 1 day following the final dose.
What are the symptoms of a lonsuf?from lonsurf.com
Tell your healthcare provider right away if you get any of the following signs and symptoms of infection during treatment with LONSURF: fever, chills, or body aches.
What happens if you take lonsuf?from lonsurf.com
LONSURF can cause a decrease in your white blood cells, red blood cells, and platelets. Low white blood cells can make you more likely to get serious infections that could lead to death. Your healthcare provider should do blood tests before you receive LONSURF, at day 15 during treatment with LONSURF, and as needed to check your blood cell counts. Your healthcare provider may lower your dose of LONSURF or stop LONSURF if you have low white blood cell or platelet counts
What is cancer care?from lonsurf.com
CancerCareis a leading national organization providing free, professional support services and information to help people manage the emotional, practical, and fi nancial challenges of cancer. Comprehensive services include counseling and support groups over the phone, online, and in-person, educational workshops, publications, and fi nancial and co-payment assistance. All services are provided by oncology social workers and world-leading cancer experts, free of charge. Learn more at cancercare.org
Does lonsufrf cause nausea?from lonsurf.com
with LONSURF include tiredness, nausea, decreased appetite, diarrhea, vomiting, abdominal pain, and fever. Tell your doctor if you have nausea, vomiting, or diarrhea that is severe or that does not go away. These are not all of the possible side effects of LONSURF. For more information, ask your healthcare provider. Call your doctor for medical advice about side effects.
Is lonsurf safe for children?from lonsurf.com
LONSURF®(trifl uridine and tipiracil) is a prescription medicine used to treat people with colon or rectal cancer that has spread to other parts of the body and who have been previously treated with or cannot receive certain chemotherapy medicines. It is not known if LONSURF is safe and effective in children. In a clinical trial, half of the patients treated with LONSURF were still alive at 7.1 months and half of the patients who received placebo were still alive at 5.3 months. Worsening of the disease or death occurred in 88% of patients treated with LONSURF and 94% of patients who received placebo.
Does lonsufra have side effects?from lonsurf.com
Tell your doctor if you have nausea, vomiting, or diarrhea that is severe or that does not go away. These are not all of the possible side effects of LONSURF.
Can you get pregnant with lonsufr?from lonsurf.com
Are pregnant or plan to become pregnant. LONSURF can harm your unborn baby. Females who can become pregnant: Your healthcare provider will verify your pregnancy status before you start treatment with LONSURF. You should use effective birth control during and 6 months after the last dose of treatment with LONSURF.
What are the symptoms of a lonsuf?
Tell your healthcare provider right away if you get any of the following signs and symptoms of infection during treatment with LONSURF: fever, chills, or body aches.
What happens if you take lonsuf?
LONSURF can cause a decrease in your white blood cells, red blood cells, and platelets. Low white blood cells can make you more likely to get serious infections that could lead to death. Your healthcare provider should do blood tests before you receive LONSURF, at day 15 during treatment with LONSURF, and as needed to check your blood cell counts. Your healthcare provider may lower your dose of LONSURF or stop LONSURF if you have low white blood cell or platelet counts
Is lonsurf safe for children?
a kind of stomach cancer called gastric cancer including cancer of the gastroesophageal junction that has spread to other parts of the body and who have been previously treated or cannot receive certain chemotherapy medications. It is not known if LONSURF is safe and effective in children.
Does lonsufra have side effects?
Tell your doctor if you have nausea, vomiting, or diarrhea that is severe or that does not go away. These are not all of the possible side effects of LONSURF.
Can you get pregnant with lonsufr?
Are pregnant or plan to become pregnant. LONSURF can harm your unborn baby. Females who can become pregnant: Your healthcare provider will verify your pregnancy status before you start treatment with LONSURF. You should use effective birth control during and 6 months after the last dose of treatment with LONSURF.
Warnings and Precautions
- Severe Myelosuppression: LONSURF caused severe and life‑threatening myelosuppression (Grade 3‑4) consisting of neutropenia (38%), anemia (18%), thrombocytopenia (5%), and febrile neutropenia (3%). Two patients (0.2%) died due to neutropenic infection. A total of 12% of LONSURF‑treated patients received granulocyte‑colony stimulating factors. Obtain...
Use in Specific Populations
- Lactation:It is not known whether LONSURF or its metabolites are present in human milk. There are no data to assess the effects of LONSURF or its metabolites on the breast‑fed infant or the effects on milk production. Because of the potential for serious adverse reactions in breast‑fed infants, advise women not to breastfeed during treatment with LONSURF and for 1 day followin…
Adverse Reactions
- Most Common Adverse Drug Reactions in Patients Treated With LONSURF (≥5%):The most common adverse drug reactions in LONSURF‑treated patients vs placebo‑treated patients with mCRC, respectively, were asthenia/fatigue (52% vs 35%), nausea (48% vs 24%), decreased appetite (39% vs 29%), diarrhea (32% vs 12%), vomiting (28% vs 14%), infections (27% vs 16%), a…
Warnings and Precautions
Use in Specific Populations
- Lactation:It is not known whether LONSURF or its metabolites are present in human milk. There are no data to assess the effects of LONSURF or its metabolites on the breast‑fed infant or the effects on milk production. Because of the potential for serious adverse reactions in breast‑fed infants, advise women not to breastfeed during treatment with LONSURF and for 1 day followin…
Adverse Reactions
- Most Common Adverse Drug Reactions in Patients Treated With LONSURF (≥5%):The most common adverse drug reactions in LONSURF‑treated patients vs placebo‑treated patients with mCRC, respectively, were asthenia/fatigue (52% vs 35%), nausea (48% vs 24%), decreased appetite (39% vs 29%), diarrhea (32% vs 12%), vomiting (28% vs 14%), infections (27% vs 16%), a…