
What is the income requirements for Novartis patient assistance?
To be eligible for NPAF assistance, you must:Household SizeAnnual Household Income Threshold2 People< USD 100 0003 People< USD 125 0004 People< USD 150 000> 5 PeopleAdd USD 25 000 for each additional person1 more row
What is Mekinist used to treat?
TAFINLAR and MEKINIST are prescription medicines that can be used in combination to treat a type of lung cancer called non-small cell lung cancer (NSCLC) that has spread to other parts of the body (metastatic NSCLC), and that has a certain type of abnormal “BRAF V600E” gene.
How does Tafinlar and Mekinist work?
What kind of treatment is TAFINLAR + MEKINIST? As a targeted combination therapy, TAFINLAR + MEKINIST helps inhibit out-of-control cell growth by blocking cell-growth signals associated with the BRAF gene. TAFINLAR and MEKINIST work together, with each targeting a different point in this cell-signaling pathway.
What is the price of Mekinist?
As a guide, Mekinist tablets usually cost $3,900 for 30 tablets. With NiceRx you will pay a flat monthly fee of $49, regardless of the retail price of your medication.
How long can you take Tafinlar and Mekinist?
How long do I take TAFINLAR + MEKINIST? Keep taking TAFINLAR® (dabrafenib) capsules + MEKINIST® (trametinib) tablets for as long as your health care provider tells you. If you are experiencing side effects, please tell your health care provider as soon as possible.
Is Mekinist a targeted therapy?
What Is Trametinib (Mekinist)? Trametinib is a MEK inhibitor, which: Is a type of targeted therapy known as a signal transduction inhibitor. Helps slow or stop the growth and spread of melanoma cells.
What is the cost of Tafinlar?
Learn more about this drug here . This is a brand name drug and a generic may be available. The average cost for 120 Capsule(s), 75mg each, is $14,986.80. You can buy Tafinlar at the discounted price of $12,299.26 by using the WebMDRx coupon, a savings of 18%.
Can I take Tafinlar and MEKINIST?
TAFINLAR and MEKINIST in combination can cause serious bleeding problems, especially in your brain or stomach, that can lead to death.
Does MEKINIST need to be refrigerated?
Both medications should be taken at least 1 hour before a meal or 2 hours after a meal. Mekinist must be stored in a refrigerator (or a refrigerated lunch pack if you are traveling) in the original bottle with the lid closely tightly to protect the medication from heat, light, and moisture.
Is Mekinist FDA approved?
Basel, June 23, 2022 — Novartis today announced the US Food and Drug Administration (FDA) granted accelerated approval for Tafinlar® (dabrafenib) + Mekinist® (trametinib) for the treatment of adult and pediatric patients 6 years of age and older with unresectable or metastatic solid tumors with BRAF V600E mutation who ...
Is TAFINLAR and Mekinist chemotherapy?
Generic name: Trametinib Mekinist is the trade name for the generic chemotherapy drug trametinib. In some cases, health care professionals may use the generic name trametinib when referring to the trade name Mekinist. Drug type: Mekinist is a targeted therapy.
Is TAFINLAR chemotherapy?
Generic name: Dabrafenib Tafinlar is the trade name for the generic chemotherapy drug dabrafenib. In some cases, health care professionals may use the generic name dabrafenib when referring to the trade name Tafinlar. Drug type: Tafinlar is a targeted therapy.
What type of drug is trametinib?
Dabrafenib and trametinib are types of cancer growth blockers. They work by targeting certain proteins that help cancer cells grow. By blocking these proteins, this combination of drugs stops or slows down the growth of cancer cells.
What is PANO on Novartis?
Our Patient Assistance Now Onc ology (PANO) program was created to assist you with accessing your Novartis medicine (s) —from insurance verification to financial assistance—all through a knowledgeable and supportive call center.
What is a single point of contact for Novartis?
One single point of contact to help guide you through getting access to the Novartis medicine (s) prescribed by your doctor
Does Novartis offer out of pocket copays?
Novartis Pharmaceuticals Corporation offers several programs that can help eligible patients with out-of-pocket co-pay costs, as well as access to treatment with TAFINLAR ® (dabrafenib) capsules + MEKINIST ® (trametinib) tablets.
Is Novartis a Medicare or Medicaid?
The program is not available for patients who are enrolled in Medicare, Medicaid, or any other federal or state health care program. Novartis reserves the right to rescind, revoke, or amend this program without notice. For full Terms and Conditions, visit CoPay.NovartisOncology.com or call 1-877-577-7756. To find out if you are eligible ...
Can you get a free trial of tafinar?
With the Free Trial and Access Program, you can receive a free supply of TAFINLAR and MEKINIST for a US Food and Drug Administration–approved indication. The supply can be shipped directly to your home or another convenient location so you can start treatment immediately. Program rules may vary by product.
What is a tafinar?
TAFINLAR and MEKINIST are prescription medicines that can be used in combination to treat a type of lung cancer called non-small cell lung cancer (NSCLC) that has spread to other parts of the body (metastatic NSCLC), and that has a certain type of abnormal “ BRAF V ... See More
What is PANO on Novartis?
Our Patient Assistance Now Oncology (PANO) program was created to assist you with accessing your Novartis medicine (s)—from insurance verification to financial assistance—all through a knowledgeable and supportive call center.
What is a single point of contact for Novartis?
One single point of contact to help guide you through getting access to the Novartis medicine (s) prescribed by your doctor
Does Novartis offer oncology?
Novartis Oncology is committed to helping you get the Novartis medicine (s) you need. Access to medicine (s) can sometimes be difficult or confusing. PANO offers resources and support designed specifically to help make that process easier.* PANO can offer the following services:
Patient Website
Our patient website is a helpful resource for patients taking TAFINLAR ® (dabrafenib) capsules + MEKINIST ® (trametinib) tablets, providing the Medication Guide, information on co-pay assistance, and downloadable support materials. Visit the site at us.tafinlarmekinist.com.
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TAFINLAR ® (dabrafenib) capsules, in combination with MEKINIST ® (trametinib) tablets, is indicated for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations as detected by an FDA-approved test.
How long to wait to resume mekinist?
Withhold MEKINIST if RPED is diagnosed. If resolution of the RPED is documented on repeat ophthalmologic evaluation within 3 weeks, resume MEKINIST at the same or a reduced dose. If no improvement after 3 weeks, resume at a reduced dose or permanently discontinue MEKINIST.
What is tafinar used for?
Indications TAFINLAR, in combination with MEKINIST, is indicated for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations as detected by an FDA-approved test.
How to assess LVEF?
Assess LVEF by echocardiogram or multigated acquisition (MUGA) scan before initiation of the combination, 1 month after initiation, and then at 2- to 3-month intervals while on treatment. Withhold TAFINLAR for symptomatic cardiomyopathy or asymptomatic left ventricular dysfunction of >20% from baseline that is below institutional LLN. Resume TAFINLAR at the same dose level upon recovery of cardiac function to at least the institutional LLN for LVEF and absolute decrease ≤10% compared to baseline. For an asymptomatic absolute decrease in LVEF of 10% or greater from baseline that is below the LLN, withhold MEKINIST for up to 4 weeks. If improved to normal LVEF value, resume at a lower dose. If no improvement to normal LVEF value within 4 weeks, permanently discontinue MEKINIST. For symptomatic cardiomyopathy or an absolute decrease in LVEF of >20% from baseline that is below LLN, permanently discontinue MEKINIST.
Does tafinar cause malignancies?
Based on its mechanism of action, TAFINLAR may promote the growth and development of malignancies with activation of monomeric G protein (RAS) through mutation or other mechanisms. Across clinical trials of TAFINLAR monotherapy and the combination, noncutaneous malignancies occurred in 1% of patients.
Is tafinar a melanoma drug?
TAFINLAR, in combination with MEKINIST, is indicated for the adjuvant treatment of patients with melanoma with BRAF V600E or V600K mutations, as detected by an FDA-approved test, and involvement of lymph node (s), following complete resection.
How to contact Novartis oncology?
Encourage your patients to find out if they are eligible to enroll in the Novartis Oncology Universal Co-pay Program by visiting Copay.NovartisOncology.com or calling 1-877-577-7756.
Is tafinar safe for melanoma?
Limitation of Use: TAFINLAR is not indicated for the treatment of patients with wild-type BRAF melanoma.