What is Nexavar used to treat?
NEXAVAR is a prescription medicine used to treat: a type of liver cancer called hepatocellular carcinoma (HCC) that cannot be removed by surgery. a type of kidney cancer called renal cell carcinoma (RCC)
Can I take Nexavar If I am pregnant?
Your healthcare provider should do a pregnancy test before you start treatment with NEXAVAR. Use effective birth control (contraception) during your treatment with NEXAVAR and for 6 months after the last dose of NEXAVAR. For males with female partners who are able to become pregnant:
How do I submit my application to the Bayer Patient Assistance Foundation?
The completed and signed application can be submitted by fax or mail: Fax: 1-866-575-6568 Mail: Bayer US Patient Assistance Foundation P.O. Box 5670, Louisville, KY 40255
When should I stop taking Nexavar before surgery?
You should stop taking NEXAVAR at least 10 days before planned surgery. Your healthcare provider should tell you when you may start taking NEXAVAR again after surgery. changes in the electrical activity of your heart called QT prolongation. QT prolongation can cause irregular heartbeats that can be life threatening.
What is the cost of Nexavar?
The cost for Nexavar oral tablet 200 mg is around $24,033 for a supply of 120 tablets, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans. This Nexavar price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
Where can I get sorafenib?
NEXAVAR tablets are available by prescription only and distributed through your healthcare professional (HCP), as well as different types of pharmacies: a network of specialty pharmacy providers (SPPs) and dispensing pharmacies. Your insurance company may require you to fill your prescription through an SPP.
How do people afford Gleevec?
Novartis Oncology Universal Co-pay Program – To understand your out-of-pocket costs for Gleevec and to see if you are eligible to pay $10 for a 30-day supply with the Gleevec $10 Co-Pay Card, call 1-866-GLEEVEC (1-866-453-3832) or visit enroll in the Novartis Oncology Universal Co-pay Program.
Who makes Nexavar?
Bayer sells a month's supply, 120 tablets, of Nexavar for₹280,000 (US$3,500).
Does Nexavar cause hair loss?
These are less common side effects for patients receiving Nexavar, when compared with those receiving placebo: High blood pressure (particularly in first 6 weeks of treatment) Hair loss (thinning or patchy hair loss) Nausea.
Is Nexavar a chemotherapy?
What Is Nexavar? Nexavar (sorafenib) is a cancer (chemotherapeutic) medication used to treat a type of kidney cancer called advanced renal cell carcinoma. Nexavar is also used to treat liver cancer.
What is the income requirements for Novartis patient assistance?
To be eligible for NPAF assistance, you must:Household SizeAnnual Household Income Threshold2 People< USD 100 0003 People< USD 125 0004 People< USD 150 000> 5 PeopleAdd USD 25 000 for each additional person1 more row
Does Medicare pay for Gleevec?
Yes. 100% of Medicare prescription drug plans cover this drug.
Is Gleevec considered chemotherapy?
Imatinib (Gleevec®) is a Chemotherapy Regimen for Chronic Myeloid Leukemia (CML)
What is the success rate of sorafenib?
Median overall survival was 26.1 months with overall 6- and 12-month survival rates of 92.1 and 85%, respectively. Median time to radiological progression was 8 months. The progression-free rate was 64.3%.
Is Nexavar generic?
Currently, no generic version of Nexavar is available in the U.S. The FDA has approved Nexavar, or sorafenib, to treat thyroid, liver and kidney cancer.
When was Nexavar FDA approved?
Approval Date: 12/20/2005.
What is the brand name for sorafenib?
Sorafenib is a cancer treatment and is also known by its brand name, Nexavar. Sorafenib is a targeted cancer drug and is also known by its brand name, Nexavar. It is a possible treatment for: a type of liver cancer called hepatocellular carcinoma.
What is the success rate of sorafenib?
Median overall survival was 26.1 months with overall 6- and 12-month survival rates of 92.1 and 85%, respectively. Median time to radiological progression was 8 months. The progression-free rate was 64.3%.
How long do you take sorafenib for?
Sorafenib is given for cancer. It is taken twice a day. Take the tablets either when your stomach is empty (which means taking your doses an hour before a meal or waiting until two hours afterwards), or after low-fat meals....About sorafenib.Type of medicineA kinase inhibitor anti-cancer medicineAvailable asTablets2 more rows•Jul 21, 2020
How long is sorafenib Effective?
Overall response and efficacy The median duration of sorafenib treatment was 3.6 months (range: 0.1–49.5 months), and the median follow‐up period was 8.6 months (range: 0.4–54.3 months).
How long after nexavar is used?
Use effective birth control (contraception) during your treatment with NEXAVAR and for 6 months after the last dose of NEXAVAR. For males with female partners who are able to become pregnant: Use effective birth control (contraception) during your treatment with NEXAVAR and for 3 months after the last dose of NEXAVAR.
What does Nexavar test for?
Your healthcare provider may do tests during your treatment with NEXAVAR to check the levels of potassium, magnesium, and calcium in your blood, and check the electrical activity of your heart with an electrocardiogram ( ECG). Tell your healthcare provider right away if you feel faint, lightheaded, dizzy or feel your heart beating irregularly ...
How to know if Nexavar is working?
Your healthcare provider will do blood tests to check your liver function regularly during your treatment with NEXAVAR. Tell your healthcare provider right away if you develop any of the following symptoms: yellowing of your skin or the whites of your eyes. dark “tea-colored” urine.
How long before surgery can you stop Nexavar?
Tell your healthcare provider if you plan to have any surgery before starting or during treatment with NEXAVAR. You should stop taking NEXAVAR at least 10 days before planned surgery. Your healthcare provider should tell you when you may start taking NEXAVAR again after surgery.
What are the symptoms of a heart attack?
Get emergency help right away if you get symptoms such as chest pain, shortness of breath, racing heartbeat, swelling in lower legs, feet and abdomen, feel lightheaded or faint, tiredness, nausea, vomiting, or sweat a lot. increased risk of bleeding.
What is the name of the cancer that can no longer be treated with radioactive iodine?
a type of thyroid cancer called differentiated thyroid carcinoma (DTC) that can no longer be treated with radioactive iodine and is progressing
How do you know if you have a rash on your hands?
Tell your healthcare provider if you have any of the following symptoms: skin rash. skin redness. pain or swelling. blistering and peeling of your skin . blistering and peeling on the inside of your mouth. blisters on the palms of your hand or soles of your feet.
How long after Nexavar can you breastfeed?
Do not breastfeed during treatment with NEXAVAR and for 2 weeks after receiving the last dose of NEXAVAR. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
What is QT prolongation?
changes in the electrical activity of your heart called QT prolongation. QT prolongation can cause irregular heartbeats that can be life threatening. Your healthcare provider may do tests during your treatment with NEXAVAR to check the levels of potassium, magnesium, and calcium in your blood, and check the electrical activity of your heart with an electrocardiogram (ECG). Tell your healthcare provider right away if you feel faint, lightheaded, dizzy or feel your heart beating irregularly or fast during your treatment with NEXAVAR.
What are the symptoms of a heart attack?
Get emergency help right away if you get symptoms such as chest pain, shortness of breath, racing heartbeat, swelling in lower legs, feet and abdomen, feel lightheaded or faint, tiredness, nausea, vomiting, or sweat a lot. increased risk of bleeding.
What is the name of the cancer that can no longer be treated with radioactive iodine?
a type of thyroid cancer called differentiated thyroid carcinoma (DTC) that can no longer be treated with radioactive iodine and is progressing
How do you know if you have a symtom?
Tell your healthcare provider right away if you develop any of the following symptoms: yellowing of your skin or the whites of your eyes. dark “tea-colored” urine. light-colored bowel movements (stools) worsening nausea or vomiting. pain on the right side of your stomach area.
How do you know if you have a rash on your hands?
Tell your healthcare provider if you have any of the following symptoms: skin rash. skin redness. pain or swelling. blistering and peeling of your skin . blistering and peeling on the inside of your mouth. blisters on the palms of your hand or soles of your feet.
Can Nexavar cause bleeding?
increased risk of bleeding. Bleeding is a common side effect of NEXAVAR that can be serious and can lead to death. Tell your healthcare provider right away if you have any signs of bleeding during treatment with NEXAVAR:
What are the most common laboratory abnormalities observed in the Nexavar study?
In the DTC study, the most common laboratory abnormalities observed in the NEXAVAR arm versus the placebo arm, respectively, were elevated ALT (59% vs. 24%), elevated AST (54% vs. 15%), and hypocalcemia (36% vs. 11%). The relative increase for the following laboratory abnormalities observed in NEXAVAR-treated DTC patients as compared to placebo-treated patients is similar to that observed in the RCC and HCC studies: lipase, amylase, hypokalemia, hypophosphatemia, neutropenia, lymphopenia, anemia, and thrombocytopenia.
What is the treatment for hepatocellular carcinoma?
STIVARGA is indicated for the treatment of patients with hepatocellular carcinoma (HCC) who have been previously treated with sorafenib.
What is Nexavar used for?
NEXAVAR is indicated for the treatment of patients with advanced renal cell carcinoma (RCC). NEXAVAR is indicated for the treatment of patients with locally recurrent or metastatic, progressive, differentiated thyroid carcinoma (DTC) that is refractory to radioactive iodine treatment.
How long after Nexavar can you breastfeed?
Lactation: Because of the potential for serious adverse reactions in a breastfed child from NEXAVAR, advise lactating women not to breastfeed during treatment with NEXAVAR and for 2 weeks after the last dose.
What is the incidence of ischemia in a nexavar group?
Cardiovascular Events: In the SHARP (HCC) study, the incidence of cardiac ischemia/infarction was 2.7% in NEXAVAR-treated patients compared with 1.3% for placebo-treated group. In the TARGET (RCC) study, the incidence of cardiac ischemia/infarction was higher in the NEXAVAR-treated group (2.9%) compared with the placebo-treated group (0.4%). In the DECISION (DTC) study, the incidence of cardiac ischemia/infarction was 1.9% in the NEXAVAR-treated group compared with 0% in the placebo-treated group. Patients with unstable coronary artery disease or recent myocardial infarction were excluded from this study. Consider temporary or permanent discontinuation of NEXAVAR in patients who develop cardiovascular events.
How long to wait to take Nexavar after surgery?
Withhold NEXAVAR for at least 10 days prior to elective surgery. Do not administer for at least 2 weeks following major surgery and until adequate wound healing.
What is hepatotoxicity in STIVARGA?
Hepatotoxicity: Severe drug-induced liver injury with fatal outcome occurred in STIVARGA-treated patients across all clinical trials. In most cases, liver dysfunction occurred within the first 2 months of therapy and was characterized by a hepatocellular pattern of injury. In hepatocellular carcinoma (HCC), there was no increase in the incidence of fatal hepatic failure as compared to placebo.
How long after nexavar is used?
Use effective birth control (contraception) during your treatment with NEXAVAR and for 6 months after the last dose of NEXAVAR. For males with female partners who are able to become pregnant: Use effective birth control (contraception) during your treatment with NEXAVAR and for 3 months after the last dose of NEXAVAR.
How to know if Nexavar is working?
Your healthcare provider will do blood tests to check your liver function regularly during your treatment with NEXAVAR. Tell your healthcare provider right away if you develop any of the following symptoms: yellowing of your skin or the whites of your eyes. dark “tea-colored” urine.
What is Nexavar used for?
NEXAVAR is a prescription medicine used to treat: a type of liver cancer called hepatocellular carcinoma (HCC) that cannot be removed by surgery. a type of kidney cancer called renal cell carcinoma (RCC) a type of thyroid cancer called differentiated thyroid carcinoma (DTC) that can no longer be treated with radioactive iodine and is progressing.
What is QT prolongation?
changes in the electrical activity of your heart called QT prolongation. QT prolongation can cause irregular heartbeats that can be life threatening. Your healthcare provider may do tests during your treatment with NEXAVAR to check the levels of potassium, magnesium, and calcium in your blood, and check the electrical activity of your heart with an electrocardiogram (ECG). Tell your healthcare provider right away if you feel faint, lightheaded, dizzy or feel your heart beating irregularly or fast during your treatment with NEXAVAR.
What are the symptoms of a heart attack?
Get emergency help right away if you get symptoms such as chest pain, shortness of breath, racing heartbeat, swelling in lower legs, feet and abdomen, feel lightheaded or faint, tiredness, nausea, vomiting, or sweat a lot. increased risk of bleeding.
What is the name of the cancer that can no longer be treated with radioactive iodine?
a type of thyroid cancer called differentiated thyroid carcinoma (DTC) that can no longer be treated with radioactive iodine and is progressing
How do you know if you have a rash on your hands?
Tell your healthcare provider if you have any of the following symptoms: skin rash. skin redness. pain or swelling. blistering and peeling of your skin . blistering and peeling on the inside of your mouth. blisters on the palms of your hand or soles of your feet.
What is Nexavar holder?
A holder for your NEXAVAR tablets, which can help you organize your doses throughout the week
What is QT prolongation?
changes in the electrical activity of your heart called QT prolongation. QT prolongation can cause irregular heartbeats that can be life threatening. Your healthcare provider may do tests during your treatment with NEXAVAR to check the levels of potassium, magnesium, and calcium in your blood, and check the electrical activity of your heart with an electrocardiogram (ECG). Tell your healthcare provider right away if you feel faint, lightheaded, dizzy or feel your heart beating irregularly or fast during your treatment with NEXAVAR.
How to report Nexavar side effects?
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What are the symptoms of a heart attack?
Get emergency help right away if you get symptoms such as chest pain, shortness of breath, racing heartbeat, swelling in lower legs, feet and abdomen, feel lightheaded or faint, tiredness, nausea, vomiting, or sweat a lot.
Can Nexavar cause liver problems?
liver problems (drug-induced hepatitis). NEXAVAR may cause liver problems that may lead to liver failure and death. Your healthcare provider will do blood tests to check your liver function regularly during your treatment with NEXAVAR. Tell your healthcare provider right away if you develop any of the following symptoms:
Can Nexavar cause bleeding?
increased risk of bleeding. Bleeding is a common side effect of NEXAVAR that can be serious and can lead to death. Tell your healthcare provider right away if you have any signs of bleeding during treatment with NEXAVAR:
Does Nexavar cause fertility problems?
NEXAVAR may cause fertility problems in males. This may affect your ability to father a child. Talk to your healthcare provider if this is a concern for you.
What are the most common laboratory abnormalities observed in the Nexavar study?
In the DTC study, the most common laboratory abnormalities observed in the NEXAVAR arm versus the placebo arm, respectively, were elevated ALT (59% vs. 24%), elevated AST (54% vs. 15%), and hypocalcemia (36% vs. 11%). The relative increase for the following laboratory abnormalities observed in NEXAVAR-treated DTC patients as compared to placebo-treated patients is similar to that observed in the RCC and HCC studies: lipase, amylase, hypokalemia, hypophosphatemia, neutropenia, lymphopenia, anemia, and thrombocytopenia.
What is the treatment for hepatocellular carcinoma?
STIVARGA is indicated for the treatment of patients with hepatocellular carcinoma (HCC) who have been previously treated with sorafenib.
How long after Nexavar can you breastfeed?
Lactation: Because of the potential for serious adverse reactions in a breastfed child from NEXAVAR, advise lactating women not to breastfeed during treatment with NEXAVAR and for 2 weeks after the last dose.
What is Nexavar used for?
NEXAVAR is indicated for the treatment of patients with advanced renal cell carcinoma (RCC). NEXAVAR is indicated for the treatment of patients with locally recurrent or metastatic, progressive, differentiated thyroid carcinoma (DTC) that is refractory to radioactive iodine treatment.
How long to wait to take Nexavar after surgery?
Withhold NEXAVAR for at least 10 days prior to elective surgery. Do not administer for at least 2 weeks following major surgery and until adequate wound healing.
What is the incidence of ischemia in a nexavar group?
Cardiovascular Events: In the SHARP (HCC) study, the incidence of cardiac ischemia/infarction was 2.7% in NEXAVAR-treated patients compared with 1.3% for placebo-treated group. In the TARGET (RCC) study, the incidence of cardiac ischemia/infarction was higher in the NEXAVAR-treated group (2.9%) compared with the placebo-treated group (0.4%). In the DECISION (DTC) study, the incidence of cardiac ischemia/infarction was 1.9% in the NEXAVAR-treated group compared with 0% in the placebo-treated group. Patients with unstable coronary artery disease or recent myocardial infarction were excluded from this study. Consider temporary or permanent discontinuation of NEXAVAR in patients who develop cardiovascular events.
What is access services by Bayer?
Access Services by Bayer ™ is a free support program available to eligible patients who have been prescribed NEXAVAR ® (sorafenib). Access Services by Bayer provides patients with information about their therapy, helps them evaluate their financial assistance options, and offers education and support to health care professionals.
What is Nexavar used for?
Nexavar has been approved by the FDA for treatment of advanced kidney cancer. Nexavar is administered in tablet form.
How many Americans can't afford medication?
There are over 100 million Americans that either can‚t afford their medication or are struggling to afford their medication. We aim to help each and every American in that situation.
Does Bayer offer Nexavar?
Nexavar REACH Program, a patient assistance program provided by Bayer HealthCare Pharmaceuticals, offers Nexavar at no cost to those who are eligible for the program. Eligibility is based off of the following requirements: