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Does Novartis have a patient assistance program?
Novartis Patient Assistance Foundation provides medicines at no cost to eligible US patients who are experiencing financial hardship.
Can I take Tafinlar and MEKINIST together?
TAFINLAR and MEKINIST in combination can cause serious bleeding problems, especially in your brain or stomach, that can lead to death.
What is Tafinlar and MEKINIST used for?
TAFINLAR and MEKINIST are prescription medicines that can be used in combination to treat a type of lung cancer called non-small cell lung cancer (NSCLC) that has spread to other parts of the body (metastatic NSCLC), and that has a certain type of abnormal “BRAF V600E” gene.
How long does Tafinlar and MEKINIST work?
After 3 years, 45% of people who were taking Tafinlar and Mekinist — and 32% of people taking a BRAF inhibitor alone — were still alive. After 5 years, about 34% of people taking the combination were still alive.
Does MEKINIST need to be refrigerated?
Both medications should be taken at least 1 hour before a meal or 2 hours after a meal. Mekinist must be stored in a refrigerator (or a refrigerated lunch pack if you are traveling) in the original bottle with the lid closely tightly to protect the medication from heat, light, and moisture.
How long can you take trametinib?
For advanced cancer you take dabrafenib and trametinib for as long as they are working and the side effects aren't too bad. If you're having this combination of drugs to prevent melanoma skin cancer coming back after surgery, you take them for up to 12 months.
What is the cost of Tafinlar?
Learn more about this drug here . This is a brand name drug and a generic may be available. The average cost for 120 Capsule(s), 75mg each, is $14,986.80. You can buy Tafinlar at the discounted price of $12,299.26 by using the WebMDRx coupon, a savings of 18%.
Can dabrafenib cure melanoma?
Through clinical trials, cancer researchers have found that combining dabrafenib and trametinib can treat advanced melanoma more effectively than either medication on its own. The combination also produces less serious side effects than the single drugs used alone.
Is Tafinlar chemo?
Tafinlar is the trade name for the generic chemotherapy drug dabrafenib. In some cases, health care professionals may use the generic name dabrafenib when referring to the trade name Tafinlar.
Is it better to be BRAF positive or negative?
We have demonstrated that BRAF positive patients receiving targeted treatment have significantly better survival than their BRAF negative counterparts.
Is MEKINIST chemotherapy?
Mekinist is the trade name for the generic chemotherapy drug trametinib. In some cases, health care professionals may use the generic name trametinib when referring to the trade name Mekinist. Drug type: Mekinist is a targeted therapy.
Is trametinib chemotherapy?
Trametinib is the generic name for the trade name chemotherapy drug Mekinist. In some cases, health care professionals may use the trade name Mekinist when referring to the generic name trametinib. Drug type: Trametinib is a targeted therapy.
How long can you take Dabrafenib?
You usually take dabrafenib twice a day, morning and evening, 12 hours apart. For advanced cancer, you take dabrafenib for as long as it is working and the side effects aren't too bad. You take dabrafenib for up to 12 months if you are having it to try to prevent melanoma skin cancer coming back after surgery.
What is BRAF protein?
BRAF is a gene found on chromosome seven that encodes a protein also called BRAF. This protein plays a role in cell growth by sending signals inside the cell promoting, among other functions, cell division.
Novartis Oncology Universal Co-Pay Program
Patients may be eligible for immediate co-pay savings on their next prescription:
Patient Assistance Now Oncology
Patient Assistance Now Oncology (PANO) is a support center consisting of insurance specialists and case managers who provide access to information regarding an array of services. Consider PANO your first stop for information about Novartis Oncology Patient Support programs.
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TAFINLAR, in combination with MEKINIST, is indicated for the treatment of adult and pediatric patients 6 years of age and older with unresectable or metastatic solid tumors with BRAF V600E mutation who have progressed following prior treatment and have no satisfactory alternative treatment options.
How to contact Novartis oncology?
Encourage your patients to find out if they are eligible to enroll in the Novartis Oncology Universal Co-pay Program by visiting Copay.NovartisOncology.com or calling 1-877-577-7756.
How long to wait to resume mekinist?
Withhold MEKINIST if RPED is diagnosed. If resolution of the RPED is documented on repeat ophthalmologic evaluation within 3 weeks, resume MEKINIST at the same or a reduced dose. If no improvement after 3 weeks, resume at a reduced dose or permanently discontinue MEKINIST.
What is a tafenar capsule?
TAFINLAR ® (dabrafenib) capsules, in combination with MEKINIST ® (trametinib) tablets, is indicated for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations as detected by an FDA-approved test.
How to assess LVEF?
Assess LVEF by echocardiogram or multigated acquisition (MUGA) scan before initiation of the combination, 1 month after initiation, and then at 2- to 3-month intervals while on treatment. Withhold TAFINLAR for symptomatic cardiomyopathy or asymptomatic left ventricular dysfunction of >20% from baseline that is below institutional LLN. Resume TAFINLAR at the same dose level upon recovery of cardiac function to at least the institutional LLN for LVEF and absolute decrease ≤10% compared to baseline. For an asymptomatic absolute decrease in LVEF of 10% or greater from baseline that is below the LLN, withhold MEKINIST for up to 4 weeks. If improved to normal LVEF value, resume at a lower dose. If no improvement to normal LVEF value within 4 weeks, permanently discontinue MEKINIST. For symptomatic cardiomyopathy or an absolute decrease in LVEF of >20% from baseline that is below LLN, permanently discontinue MEKINIST.
What is tafinar used for?
Indications TAFINLAR, in combination with MEKINIST, is indicated for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations as detected by an FDA-approved test.
Does tafinar cause malignancies?
Based on its mechanism of action, TAFINLAR may promote the growth and development of malignancies with activation of monomeric G protein (RAS) through mutation or other mechanisms. Across clinical trials of TAFINLAR monotherapy and the combination, noncutaneous malignancies occurred in 1% of patients.
Is tafinar a melanoma drug?
TAFINLAR, in combination with MEKINIST, is indicated for the adjuvant treatment of patients with melanoma with BRAF V600E or V600K mutations, as detected by an FDA-approved test, and involvement of lymph node (s), following complete resection.
What is a single point of contact for Novartis?
One single point of contact to help guide you through getting access to the Novartis medicine (s) prescribed by your doctor
What is PANO on Novartis?
Our Patient Assistance Now Onc ology (PANO) program was created to assist you with accessing your Novartis medicine (s) —from insurance verification to financial assistance—all through a knowledgeable and supportive call center.
Does Novartis offer out of pocket copays?
Novartis Pharmaceuticals Corporation offers several programs that can help eligible patients with out-of-pocket co-pay costs, as well as access to treatment with TAFINLAR ® (dabrafenib) capsules + MEKINIST ® (trametinib) tablets.
Does Novartis have oncology?
Novartis Oncology is committed to helping you get the Novartis medicine (s) you need. Access to medicine (s) can sometimes be difficult or confusing. PANO offers resources and support designed specifically to help make that process easier. †
Is Novartis a Medicare or Medicaid?
The program is not available for patients who are enrolled in Medicare, Medicaid, or any other federal or state health care program. Novartis reserves the right to rescind, revoke, or amend this program without notice. For full Terms and Conditions, visit CoPay.NovartisOncology.com or call 1-877-577-7756. To find out if you are eligible ...
Can you get a free trial of tafinar?
With the Free Trial and Access Program, you can receive a free supply of TAFINLAR and MEKINIST for a US Food and Drug Administration–approved indication. The supply can be shipped directly to your home or another convenient location so you can start treatment immediately. Program rules may vary by product.
What is a single point of contact for Novartis?
One single point of contact to help guide you through getting access to the Novartis medicine (s) prescribed by your doctor
What is PANO on Novartis?
Our Patient Assistance Now Oncology (PANO) program was created to assist you with accessing your Novartis medicine (s)—from insurance verification to financial assistance—all through a knowledgeable and supportive call center.
What is a tafinar?
TAFINLAR and MEKINIST are prescription medicines that can be used in combination to treat a type of lung cancer called non-small cell lung cancer (NSCLC) that has spread to other parts of the body (metastatic NSCLC), and that has a certain type of abnormal “ BRAF V ... See More
Does Novartis offer oncology?
Novartis Oncology is committed to helping you get the Novartis medicine (s) you need. Access to medicine (s) can sometimes be difficult or confusing. PANO offers resources and support designed specifically to help make that process easier.* PANO can offer the following services:
What is PANO on Novartis?
Our Patient Assistance Now Oncology (PANO) program was created to assist you with accessing your Novartis medicine (s)—from insurance verification to financial assistance—all through a knowledgeable and supportive call center.
Does Novartis provide financial assistance?
Novartis Pharmaceuticals Corporation does not guarantee success in obtaining reimbursement or financial assistance. Third-party payment for medical products and services is affected by numerous factors, not all of which can be anticipated or resolved. There are eligibility requirements for different financial assistance programs.
Does Novartis have patient support?
At Novartis Oncology, patients are our priority. That's why we go beyond the medicines we make to bring you the support and resources you need to help you during your journey. From financial assistance to online support, learn how we can make it as simple as possible for you to get connected to resources that can help.
Is Novartis responsible for the site?
You are now leaving the Novartis site and moving to an external website independently operated and not managed by Novartis Pharmaceuticals Corporation. Novartis assumes no responsibility for the site. If you do not wish to leave this site, click Cancel. Or click OK to continue.
Does Novartis have oncology?
Novartis Oncology is committed to helping you get the Novartis medicines you need. Access to medicine (s) can sometimes be difficult or confusing. PANO offers resources and support designed specifically to help make that process easier.
What is Novartis patient support?
Novartis Oncology Patient Support is designed to help meet the needs of patients and caregivers by making it easier to access Novartis On cology medicine (s). Patient Assistance Now Oncology (PANO) representatives will guide you to patient support options that fit your needs.
Does Novartis Pharmaceuticals guarantee reimbursement?
Unique programs designed to work with you when they're needed most. Novartis Pharmaceuticals Corporation does not guarantee success in obtaining reimbursement or financial assistance. Third-party payment for medical products and services is affected by numerous factors, not all of which can be anticipated or resolved.
What is a mekinist?
Mekinist (trametinib) is a member of the multikinase inhibitors drug class and is commonly used for Melanoma - Metastatic, Non-Small Cell Lung Cancer, and Thyroid Cancer.
What is a patient assistance program?
Patient assistance programs (PAPs) are usually sponsored by pharmaceutical companies and provide free or discounted medicines to low income or uninsured and under-insured people who meet specific guidelines. Eligibility requirements vary for each program.
How much does a free drug card save?
The free Drugs.com Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions.
Does Clozarila have a pharmacy card?
For Focalin XR, Clozaril, and Ritalin LA, Clozarila pharmacy card will be issued. All other medication will be shipped directly to the patient, unless otherwise noted. *Additional products may be available. Please contact the program for a complete product listing. www.pap.novartis.com
Is Mekinist a generic?
Mekinist is available as a brand name drug only, a generic version is not yet available. For more information, read about generic Mekinist availability . This Mekinist price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
