What does Opdivo cost?
Depending on the dose, Opdivo can cost $6,580 per infusion. According to the manufacturer, more than 60 percent of patients pay only a quarter of this price or less with coverage from Medicare, Medicaid, or other insurance plans.
How much does Opdivo and yervoy cost?
The combination of Yervoy (ipilumumab) and Opdivo (nivolumab) will cost more than $250,000 per year. Bristol-Myers Squibb is also testing the Yervoy/Opdivo combo for treatment of lung cancer.
What is OPDIVO used for?
A drug that binds to the protein PD-1 to help immune cells kill cancer cells better and is used to treat many different types of cancer. These include cancers that express the protein PD-L1 or that have certain mutations (changes) in genes involved in DNA repair.
How much longer can you live with Opdivo and Yervoy?
According to 6.5 year data from CheckMate-067, median overall survival (OS) for patients with advanced melanoma was 72.1 months with Opdivo plus Yervoy, compared with 36.9 months for patients received Opdivo alone and 19.9 months for Yervoy monotherapy.
When should I stop using Opdivo?
If your doctor confirms you had a serious allergic reaction to Opdivo, they'll stop your Opdivo treatment and decide if another cancer treatment is right for you.
Is Opdivo well tolerated?
Opdivo and Yervoy are immunotherapy medications used to treat certain types of cancer. Opdivo and Yervoy can work together to better fight cancer by mobilizing your immune system. These medications are usually well-tolerated, but they can cause some serious side effects.
How quickly does Opdivo work?
How long does Opdivo take to work?Cancer Type (Trial name)Median Time to ResponseSquamous cell carcinoma of the head and neck (CheckMate-141)Opdivo: 2.1 months (range 1.8-7.4) vs Investigator's choice (methotrexate, docetaxel or cetuximab) : 2.0 (range 1.9-4.6)6 more rows
What are the signs that immunotherapy is working?
What are the signs that immunotherapy is working? Immunotherapy is deemed effective when a tumor shrinks in size or at least stops growing. It is important to note that immunotherapy drugs may take longer to shrink tumors compared to traditional treatments like chemotherapy.
How much does nivolumab cost per month?
Of note, the monthly price of nivolumab-ipilimumab combination therapy would have to be reduced from $26 425 to $5058 (an 80.9% reduction) to be cost-effective compared with chemotherapy.
What is the cost of ipilimumab?
Adjuvant Ipilimumab for Melanoma—The $1.8 Million per Patient Regimen. We are all now used to hearing the broken record berating the high prices of cancer drugs.
What does Opdivo and Yervoy treat?
OPDIVO® (nivolumab) is a prescription medicine used in combination with YERVOY® (ipilimumab) to treat people with a type of skin cancer called melanoma that has spread or cannot be removed by surgery (advanced melanoma). It is not known if OPDIVO is safe and effective in children younger than 18 years of age.
What is the most common type of immunotherapy?
Naked monoclonal antibodies are the most common type used in cancer treatment. They're called naked because they're unattached to anything. These antibodies boost your immune system's response against the cancer, or block antigens that help the cancer grow and spread.
What is OPDIVO used for?
OPDIVO is indicated for the adjuvant treatment of completely resected esophageal or gastroesophageal junction cancer with residual pathologic disease in patients who have received neoadjuvant chemoradiotherapy (CRT). OPDIVO, in combination with fluoropyrimidine- and platinum-containing chemotherapy, is indicated for the treatment ...
What is OPDIVO in combination with?
OPDIVO, in combination with YERVOY ® (ipilimumab), is indicated for the treatment of patients with unresectable or metastatic melanoma.
What is odivo in cancer?
OPDIVO ® (nivolumab), in combination with YERVOY ® (ipilimumab), is indicated for the treatment of adults and pediatric patients 12 years and older with microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) metastatic colorectal cancer (CRC) that has progressed following treatment with a fluoropyrimidine, oxaliplatin, and irinotecan. This indication is approved under accelerated approval based on overall response rate and duration of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trials.
What is opdivo nivolumab?
OPDIVO ® (nivolumab) is indicated for the treatment of patients with locally advanced or metastatic urothelial carcinoma who have disease progression during or following platinum-containing chemotherapy or have disease progression within 12 months of neoadjuvant or adjuvant treatment with platinum-containing chemotherapy.
What is the name of the drug that is used to treat pleural mesothelioma?
OPDIVO ® (nivolumab), in combination with YERVOY ® (ipilimumab), is indicated for the first-line treatment of adult patients with unresectable malignant pleural mesothelioma (MPM).
What is nivolumab used for?
OPDIVO ® (nivolumab) is indicated for the treatment of patients with metastatic non-small cell lung cancer (NSCLC) with progression on or after platinum-based chemotherapy. Patients with EGFR or ALK genomic tumor aberrations should have disease progression on FDA-approved therapy for these aberrations prior to receiving OPDIVO.
Does opdivo cause liver toxicity?
OPDIVO in combination with cabozantinib can cause hepatic toxicity with higher frequencies of Grade 3 and 4 ALT and AST elevations compared to OPDIVO alone. Consider more frequent monitoring of liver enzymes as compared to when the drugs are administered as single agents. In patients receiving OPDIVO and cabozantinib, Grades 3 and 4 increased ALT or AST were seen in 11% of patients.
What is OPDIVO used for?from opdivohcp.com
OPDIVO is indicated for the adjuvant treatment of completely resected esophageal or gastroesophageal junction cancer with residual pathologic disease in patients who have received neoadjuvant chemoradiotherapy (CRT). OPDIVO, in combination with fluoropyrimidine- and platinum-containing chemotherapy, is indicated for the treatment ...
What is opdivo nivolumab?from opdivohcp.com
OPDIVO ® (nivolumab) is indicated for the treatment of patients with locally advanced or metastatic urothelial carcinoma who have disease progression during or following platinum-containing chemotherapy or have disease progression within 12 months of neoadjuvant or adjuvant treatment with platinum-containing chemotherapy.
What is odivo in cancer?from opdivohcp.com
OPDIVO ® (nivolumab), in combination with YERVOY ® (ipilimumab), is indicated for the treatment of adults and pediatric patients 12 years and older with microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) metastatic colorectal cancer (CRC) that has progressed following treatment with a fluoropyrimidine, oxaliplatin, and irinotecan. This indication is approved under accelerated approval based on overall response rate and duration of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trials.
What is the name of the drug that is used to treat pleural mesothelioma?from opdivohcp.com
OPDIVO ® (nivolumab), in combination with YERVOY ® (ipilimumab), is indicated for the first-line treatment of adult patients with unresectable malignant pleural mesothelioma (MPM).
What is nivolumab used for?from opdivohcp.com
OPDIVO ® (nivolumab) is indicated for the treatment of patients with metastatic non-small cell lung cancer (NSCLC) with progression on or after platinum-based chemotherapy. Patients with EGFR or ALK genomic tumor aberrations should have disease progression on FDA-approved therapy for these aberrations prior to receiving OPDIVO.
Can opdivo cause fetal harm?from opdivohcp.com
Based on its mechanism of action and findings from animal studies, OPDIVO and YERVOY can cause fetal harm when administered to a pregnant woman. The effects of YERVOY are likely to be greater during the second and third trimesters of pregnancy. Advise pregnant women of the potential risk to a fetus. Advise females of reproductive potential to use effective contraception during treatment with OPDIVO and YERVOY and for at least 5 months after the last dose.
Can OPDivo cause thyroid problems?from opdivohcp.com
OPDIVO and YERVOY can cause primary or secondary adrenal insufficiency, immune-mediated hypophysitis, immune-mediated thyroid disorders, and Type 1 diabetes mellitus, which can present with diabetic ketoacidosis. Withhold OPDIVO and YERVOY depending on severity (please see section 2 Dosage and Administration in the accompanying Full Prescribing Information). For Grade 2 or higher adrenal insufficiency, initiate symptomatic treatment, including hormone replacement as clinically indicated. Hypophysitis can present with acute symptoms associated with mass effect such as headache, photophobia, or visual field defects. Hypophysitis can cause hypopituitarism; initiate hormone replacement as clinically indicated. Thyroiditis can present with or without endocrinopathy. Hypothyroidism can follow hyperthyroidism; initiate hormone replacement or medical management as clinically indicated. Monitor patients for hyperglycemia or other signs and symptoms of diabetes; initiate treatment with insulin as clinically indicated.
What is opdivo used for?
OPDIVO ® (nivolumab) is a prescription medicine used to treat people with cancer of the stomach (gastric), cancer where the esophagus joins the stomach (gastroesophageal junction), and in people with esophageal adenocarcinoma. OPDIVO may be used in combination with chemotherapy that contains fluoropyrimidine and platinum when your cancer cannot be ...
What is the name of the medicine that is used to treat pleural mesothelioma?
For adults newly diagnosed with malignant pleural mesothelioma (MPM) OPDIVO ® (nivolumab) is a prescription medicine used in combination with YERVOY ® (ipilimumab) as a first treatment for adults with a type of cancer that affects the lining of the lungs and chest wall called malignant pleural mesothelioma which cannot be removed by surgery.
What is nivolumab used for?
OPDIVO ® (nivolumab) is a prescription medicine used to treat people with head and neck cancer (squamous cell carcinoma) that has come back or spread and you have tried chemotherapy that contains platinum and it did not work or is no longer working.
Does opdivo work for bladder cancer?
For people with previously treated advanced bladder cancer (urothelial carcinoma) OPDIVO ® (nivolumab) is a prescription medicine used to treat people with bladder cancer (urothelial carcinoma) that has spread or grown and you have tried chemotherapy that contains platinum, and it did not work or is no longer working.
Is opdivo a prescription?
There is ongoing evaluation of clinical benefit of OPDIVO for this use. OPDIVO ® (nivolumab) is a prescription medicine used in combination with YERVOY ® (ipilimumab) to treat people with liver cancer (hepatocellular carcinoma) if you have previously received treatment with sorafenib.
Does opdivo work?
OPDIVO ® (nivolumab) is a prescription medicine used to treat people with a type of advanced stage lung cancer (called non-small cell lung cancer) that has spread or grown and you have tried chemotherapy that contains platinum, and it did not work or is no longer working.
Is OPDivo safe for children?
It is not known if OPDIVO is safe and effective in children younger than 12 years of age with MSI-H or dMMR metastatic colorectal cancer, or in children younger than 18 years of age for the treatment of any other cancers. OPDIVO (10 mg/mL) and YERVOY (5 mg/mL) are injections for intravenous. (IV) use.
Appeals Assistance
If the patient's insurer has denied coverage, the denial may be appealed. BMS Access Support may be able to assist by providing information about the appeals process.
Identification of Charitable Organizations
BMS Access Support may help to identify charitable organizations that may provide funding for eligible patients seeking financial assistance for prescription medication.
Available medicines
Find out if the medicine your doctor prescribed is available through the Bristol Myers Squibb Patient Assistance Foundation.
Eligibility
Complete a brief assessment to see if you might be eligible for assistance.
How to apply
We'll need some information from both you and your doctor to process your application.
