Janssen CarePath Oral PAH Savings Program can help eligible patients save on their out-of-pocket medication costs for OPSUMIT ®. Your eligible patients will pay $5 per prescription fill with a $20,000 maximum program benefit per calendar year across all oral PAH therapies in the program.
Full Answer
How can I get financial assistance for my Patients taking Opsumit®?
There are several programs that can provide financial assistance to your patients taking OPSUMIT ®. For information on these programs, call a Janssen CarePath Care Coordinator at 866-228-3546, Monday-Friday, 8 AM to 8 PM ET.
How can I save on my Opsumit ® out-of-pocket costs?
Janssen CarePath Oral PAH Savings Program can help eligible patients save on their out-of-pocket medication costs for OPSUMIT ®. Your eligible patients will pay $5 per prescription fill with a $20,000 maximum program benefit per calendar year across all oral PAH therapies in the program.
Is there a free trial offer for Opsumit ®?
A free 30-day trial offer is available for eligible patients to help them become familiar with OPSUMIT ®. At the conclusion of the program, you and your patient decide if it is appropriate to continue treatment. Subject to 1 (one) use per lifetime for the first 30-day supply of OPSUMIT ®.
What are the benefits of Opsumit®?
OPSUMIT ® can: Improve your ability to exercise as measured by the 6-minute walk distance (6MWD). In a clinical study of mainly WHO FC II-III patients, those taking OPSUMIT® walked, on average, 22 meters farther at Month 6 than patients not taking it
Is OPSUMIT covered by Medicare?
Do Medicare prescription drug plans cover Opsumit? Yes. 96% of Medicare prescription drug plans cover this drug.
Who is the manufacturer for Opsumit?
Authorisation detailsPublication detailsMarketing-authorisation holderJanssen-Cilag International N.V.Revision20Date of issue of marketing authorisation valid throughout the European Union20/12/2013Contact addressJanssen-Cilag International N.V. Turnhoutseweg 30 BE-2340 Beerse Belgium
How do I order Opsumit?
Please visit www.OpsumitREMS.com or call 1-866-ACTELION (1-866-228-3546) for immediate patient enrollment, or for more information about the Opsumit REMS.
What is Janssen CarePath savings program?
Janssen CarePath Savings Program for SPRAVATO® is based on medication costs only and does not include costs to give you your treatment. This program is only available to people age 18 or older using commercial or private health insurance for their Janssen medication.
How long does it take Opsumit to work?
Actelion announced positive results after 16 weeks of treatment, showing that patients receiving Opsumit had significantly reduced mean pulmonary vascular resistance (a measure of the effort required for blood to flow through the lungs) compared to the placebo-treated group.
Is there a generic for Opsumit?
Is there a generic for Opsumit (macitentan)? Opsumit (macitentan) currently does not come in a generic form. There are two other drugs in the same medication class, bosentan (Tracleer) and ambrisentan (Letairis), that are used to treat PAH and available as generics.
What is the cost of Selexipag?
Uptravi (selexipag) is a member of the agents for pulmonary hypertension drug class and is commonly used for Pulmonary Hypertension....Oral Tablet.QuantityPer unitPrice60$356.00$21,359.80
What is Group 1 pulmonary hypertension?
Group 1: Pulmonary Arterial Hypertension (PAH) WHO Group 1 refers to pulmonary arterial hypertension (PAH), which is caused when the arteries in the lungs become narrowed, thickened or stiff. The right side of the heart must work harder to push blood through these narrowed arteries.
Does Opsumit lower blood pressure?
Macitentan lowers blood pressure in your lungs, helping your heart pump blood more efficiently. Macitentan is used to treat pulmonary arterial hypertension (PAH). It improves your ability to exercise and prevents your condition from getting worse.
Does Janssen have a patient assistance program?
Janssen is committed to helping patients obtain appropriate access to our medicines. We partner with private and public payers and healthcare systems to support availability of our products and we offer and support a variety of programs and services to assist with access to and appropriate use of new treatment options.
Does Janssen CarePath work with Medicare?
If you use commercial or private health insurance, Janssen CarePath Savings Program may help you save on your out-of-pocket costs. Patients using Medicare, Medicaid, or any other federally funded programs to pay for their Janssen medication are not eligible to participate.
What is Jansen care path?
Janssen CarePath is your one source for resources focused on access, affordability, and treatment support for your patients. Our Care Coordinator team supports all the Janssen products you prescribe. We can help make it easier for you and your patients to get the resources you both may need.
Is OPSUMIT specialty pharmacy?
OPSUMIT® is not available through retail pharmacies. OPSUMIT® is distributed to patients by mail through a specialty pharmacy rather than through a retail pharmacy. When you enroll your patients, they are connected to a specialty pharmacy based on their health insurance plans or their healthcare teams' preference.
When does OPSUMIT go generic?
In Australia, US and Hungary, Macitentan patents have the expiry date of Dec 2026, Oct 2022, and Dec 2026 respectively. The longer expiration dates indicate that other will be inhibited longer from launching a generic version of the drug in these countries.
How much does macitentan cost?
Table 1Cost Comparison Table for Drugs Used for the Treatment of Pulmonary Arterial HypertensionDrug/ ComparatorStrengthPrice ($)Macitentan (Opsumit)10 mg128.3333aOther ERAsAmbrisentan (Volibris)5 mg 10 mg122.5200Bosentan (Tracleer)62.5 mg 125 mg64.178611 more rows
What drug class is OPSUMIT?
OPSUMIT is an endothelin receptor antagonist (ERA) indicated for the treatment of pulmonary arterial hypertension (PAH, WHO Group I) to reduce the risks of disease progression and hospitalization for PAH.
How much does Opsumit cost?
Depending on the health insurance plan, savings may apply toward co-pay, co-insurance or deductible. Eligible patients pay $5 per prescription fill for OPSUMIT ® with a $20,000 maximum program benefit per calendar year across all oral PAH therapies in the program. Not valid for patients using Medicare, Medicaid, or other government-funded programs to pay for their medications. Terms expire at the end of each calendar year and may change. There is no income requirement. See full eligibility requirements at OPSUMIT.JanssenCarePathSavings.com.
What is Janssen CarePath?
Janssen CarePath Oral PAH Savings Program for eligible patients with commercial or private health insurance
What is the phone number for Opsumit?
Call a Janssen CarePath Care Coordinator at 866-228-3546.
What is the phone number for Janssen Carepath?
Call a Janssen CarePath Care Coordinator at 866-228-3546, Monday−Friday, 8:00 AM to 8:00 PM ET. Multilingual phone support is available. † Independent co-pay assistance foundations have their own rules for eligibility. We cannot guarantee a foundation will help you.
Why do we review health insurance benefits?
Reviewing your health plan benefits to help answer questions you may have about insurance coverage
Does Janssen CarePath cover out-of-pocket costs?
Janssen CarePath can explain your potential out-of-pocket costs and identify cost support options that may help with managing your out-of-pocket costs—whether you have commercial or private health insurance, government-funded healthcare coverage such as Medicare or Medicaid, or have no insurance coverage:
What are strong inhibitors of CYP3A4?
Strong inhibitors of CYP3A4 like ketoconazole approximately double macitentan exposure. Many HIV drugs like ritonavir are strong inhibitors of CYP3A4. Avoid concomitant use of OPSUMIT® with strong CYP3A4 inhibitors. Use other PAH treatment options when strong CYP3A4 inhibitors are needed as part of HIV treatment.
Is Opsumit available for females?
Due to the risk of embryo-fetal toxicity, OPSUMIT ® is available for females only through a restricted program called the OPSUMIT ® REMS Program. For females of reproductive potential, exclude pregnancy prior to initiation of therapy, ensure use of acceptable contraceptive methods, and obtain monthly pregnancy tests.
Does a specialty pharmacy supply refills?
The specialty pharmacy will supply refills as long as the prescriber verifies the continued prescription and the patient complies with the OPSUMIT ® REMS Program requirements.
Do female patients have to be enrolled in OPSUMIT?
All female patients must be enrolled in the OPSUMIT ® REMS Program to receive OPSUMIT ®, due to the risks of embryo-fetal toxicity. Male patients are not required to enroll in the OPSUMIT ® REMS Program.
What is Janssen Carepath?
Janssen CarePath is your one source for access, affordability, and treatment support for your patients. Janssen CarePath helps verify insurance coverage for your patients, helps find financial assistance options for eligible patients, and provides ongoing support to help patients start and stay on prescribed Janssen medications.
Does OPSUMIT cause hemoglobin to decrease?
Decreases in hemoglobin concentration and hematocrit have occurred following administration of other ERAs and in clinical studies with OPSUMIT®. These decreases occurred early and stabilized thereafter.
Does amiodarone increase macitentan?
Moderate dual inhibitors of CYP3A4 and CYP2C9 such as fluconazole and amiodarone are predicted to increase macitentan exposure. Avoid concomitant use of OPSUMIT® with moderate dual inhibitors of CYP3A4 and CYP2C9.
What is OPSUMIT used for?
OPSUMIT ® is a prescription medicine used to treat pulmonary arterial hypertension (PAH, WHO Group 1). PAH is high blood pressure in the arteries of your lungs. OPSUMIT ® can:
Can opsumit cause birth defects?
OPSUMIT® can cause serious birth defects. See “The most important information about OPSUMIT®.”. Talk to your doctor about all your medical conditions, as well as all the medicines, vitamins, and supplements you take. OPSUMIT ® and other medicines may affect each other causing side effects.
Can a child take opsumit before menstruation?
He or she may recommend using a form of emergency birth control. If you are the parent or caregiver of a female child who started taking OPSUMIT ® before reaching puberty, check with your child regularly for any signs of puberty. Your child may reach puberty before having her first menstrual period.
Can you get pregnant if you have not had your ovaries removed?
has a uterus. has not gone through menopause (menopause means you have not had a menstrual period for at least 12 months for natural reasons, or have had your ovaries removed) You are not medically able to get pregnant if you are a woman who fits at least 1 of the following guidelines: has not started puberty.
Is Opsumit safe for children?
It is not known if OPSUMIT ® is safe and effective in children.
Can opsumit cause liver problems?
Some medicines that are like OPSUMIT® can cause liver problems. Your doctor should do blood tests to check your liver before you start OPSUMIT®. Tell your doctor if you have any of these symptoms, which could be a sign of liver problems while on OPSUMIT®: Nausea or vomiting. Pain in the upper right stomach.
Do women who are able to get pregnant have to have negative pregnancy tests?
Women who are able to get pregnant must have negative pregnancy tests:
What is a OPSUMIT?
OPSUMIT ® is a prescription medicine used to treat pulmonary arterial hypertension ( PAH, WHO Group 1). PAH is high blood pressure in the arteries of your lungs. OPSUMIT ® can: Improve your ability to exercise as measured by the 6-minute walk distance (6MWD). In a clinical study of mainly WHO FC II-III patients, those taking OPSUMIT® walked, ...
Can opsumit cause birth defects?
OPSUMIT® can cause serious birth defects. See “The most important information about OPSUMIT®.”. Talk to your doctor about all your medical conditions, as well as all the medicines, vitamins, and supplements you take. OPSUMIT ® and other medicines may affect each other causing side effects.
Can a child take opsumit before menstruation?
He or she may recommend using a form of emergency birth control. If you are the parent or caregiver of a female child who started taking OPSUMIT ® before reaching puberty, check with your child regularly for any signs of puberty. Your child may reach puberty before having her first menstrual period.
Can you get pregnant if you have not had your ovaries removed?
has a uterus. has not gone through menopause (menopause means you have not had a menstrual period for at least 12 months for natural reasons, or have had your ovaries removed) You are not medically able to get pregnant if you are a woman who fits at least 1 of the following guidelines: has not started puberty.
Is Opsumit safe for children?
It is not known if OPSUMIT ® is safe and effective in children.
Does opsumit cause decreased sperm count?
Decreased sperm counts. OPSUMIT®, and other medicines like OPSUMIT®, may cause decreased sperm counts in men who take these medicines.
Do women who are able to get pregnant have to have negative pregnancy tests?
Women who are able to get pregnant must have negative pregnancy tests:
What are strong inhibitors of CYP3A4?
Strong inhibitors of CYP3A4 like ketoconazole approximately double macitentan exposure. Many HIV drugs like ritonavir are strong inhibitors of CYP3A4. Avoid concomitant use of OPSUMIT® with strong CYP3A4 inhibitors. Use other PAH treatment options when strong CYP3A4 inhibitors are needed as part of HIV treatment.
How to talk to a PAH companion?
Patients who have enrolled can talk to a PAH Companion by calling 866-300-1818, Monday-Friday, 8 AM to 9 PM ET. *The PAH Companion Program is limited to education for patients about their Janssen therapy, its administration, and/or PAH. It is intended to supplement a patient's understanding of their therapy, and does not provide medical advice ...
Is Opsumit available for females?
Due to the risk of embryo-fetal toxicity, OPSUMIT ® is available for females only through a restricted program called the OPSUMIT ® REMS Program. For females of reproductive potential, exclude pregnancy prior to initiation of therapy, ensure use of acceptable contraceptive methods, and obtain monthly pregnancy tests.
Can opsumit be used during pregnancy?
Pregnancy: OPSUMIT ® may cause fetal harm when administered to a pregnant woman. OPSUMIT ® is contraindicated in females who are pregnant. If OPSUMIT ® is used during pregnancy, advise the patient of the potential risk to a fetus.
Does OPSUMIT cause hemoglobin to decrease?
Decreases in hemoglobin concentration and hematocrit have occurred following administration of other ERAs and in clinical studies with OPSUMIT®. These decreases occurred early and stabilized thereafter.
When to do liver enzyme test for opsumit?
Obtain liver enzyme tests prior to initiation of OPSUMIT ® and repeat during treatment as clinically indicated.
Does amiodarone increase macitentan?
Moderate dual inhibitors of CYP3A4 and CYP2C9 such as fluconazole and amiodarone are predicted to increase macitentan exposure. Avoid concomitant use of OPSUMIT® with moderate dual inhibitors of CYP3A4 and CYP2C9.
How much less likely is Opsumit to have PAH?
Patients taking OPSUMIT were 45% less likely to have their PAH progress than patients not taking it.
What happens when you have PAH?
When you have PAH, your body may produce too much of a substance called endothelin. This can cause the blood vessels in your lungs to narrow, restricting blood flow and putting strain on the heart. OPSUMIT targets the endothelin pathway specifically, and works to open these narrow blood vessels.
Can you take opsumit while pregnant?
Do not take OPSUMIT if you are pregnant or trying to get pregnant. OPSUMIT can cause serious birth defects if taken while pregnant.
What is OPSUMIT used for?
OPSUMIT ® is a prescription medicine used to treat pulmonary arterial hypertension (PAH, WHO Group 1). PAH is high blood pressure in the arteries of your lungs. OPSUMIT ® can:
Can opsumit cause birth defects?
OPSUMIT® can cause serious birth defects. See “The most important information about OPSUMIT®.”. Talk to your doctor about all your medical conditions, as well as all the medicines, vitamins, and supplements you take. OPSUMIT ® and other medicines may affect each other causing side effects.
Can a child take opsumit before menstruation?
He or she may recommend using a form of emergency birth control. If you are the parent or caregiver of a female child who started taking OPSUMIT ® before reaching puberty, check with your child regularly for any signs of puberty. Your child may reach puberty before having her first menstrual period.
Can you get pregnant if you have not had your ovaries removed?
has a uterus. has not gone through menopause (menopause means you have not had a menstrual period for at least 12 months for natural reasons, or have had your ovaries removed) You are not medically able to get pregnant if you are a woman who fits at least 1 of the following guidelines: has not started puberty.
Is Opsumit safe for children?
It is not known if OPSUMIT ® is safe and effective in children.
Can opsumit cause liver problems?
Some medicines that are like OPSUMIT® can cause liver problems. Your doctor should do blood tests to check your liver before you start OPSUMIT®. Tell your doctor if you have any of these symptoms, which could be a sign of liver problems while on OPSUMIT®: Nausea or vomiting. Pain in the upper right stomach.
Do women who are able to get pregnant have to have negative pregnancy tests?
Women who are able to get pregnant must have negative pregnancy tests:
What is The Patient Assistance Program?
The Johnson & Johnson Patient Assistance Foundation, Inc. (JJPAF) is an independent, non-profit organization that is committed to helping eligible patients without insurance coverage receive prescription products donated by Johnson & Johnson operating companies.
Program Update
Patients may now choose the option of electronic income verification. Instead of submitting a copy of their Federal tax return, they can simply check a box on the updated application form.
