How long does it take to ovulate after Ovidrel (choriogonadotropin alfa)?
It typically takes about 36 hours to ovulate after injecting Ovidrel (choriogonadotropin alfa). Since it is such a time-sensitive medication, you m...
Can Ovidrel (choriogonadotropin alfa) cause twins?
Yes. Ovidrel (choriogonadotropin alfa) can lead to twins, triplets, or more. This medication can cause more than one egg to ovulate. Please be awar...
Where do you inject Ovidrel (choriogonadotropin alfa)?
You should inject Ovidrel (choriogonadotropin alfa) in your stomach around your belly button. Just make sure it's at least 1 inch away from the bel...
What happens if Ovidrel (choriogonadotropin alfa) is left out of the refrigerator?
If Ovidrel (choriogonadotropin alfa) comes to room temperature, it is only good for 30 days. It has a much longer shelf life if kept in the refrige...
How effective is Ovidrel (choriogonadotropin alfa)?
Ovidrel (choriogonadotropin alfa) is very effective. In studies, this medication successfully caused ovulation in over 91% of people who used it.
How to administer follicle stimulating medicine?
If any of the information is unclear, consult your doctor or pharmacist. After injecting the mixing liquid (diluent) into the vial of powdered drug, gently roll the vial until the powder is completely dissolved; do not shake the injection/vial. Doing so may make this medicine ineffective. Inject this medication under the skin (subcutaneously) usually the day after your last dose of follicle stimulating medicine as directed by your doctor . Your doctor's decision to give this injection is based on laboratory and medical test results (e.g., serum estradiol, vaginal ultrasound). Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard needles and medical supplies safely. Consult your pharmacist.
What to do if you suspect an overdose?
If overdose is suspected, contact your local poison control center or emergency room immediately.
How does ovidrel work?
How Ovidrel Works. Ovidrel (injected r-hCG) acts very similar to the body's luteinizing hormone (LH) that spikes just before ovulation. 1 The role of LH in the female reproductive system is to stimulate the maturing egg (still in its follicle in the ovary) to complete the stages of growth just before ovulation.
What happens when you inject ovidrel?
When you inject Ovidrel (or any form of chorionic gonadotropin) into your body, as long as follicles in the ovary are at the right stage of maturation , hCG triggers the eggs to go through a final growth spurt and ovulate (be released from the follicles) within 36 hours.
What is Ovidrel made of?
Ovidrel is composed of recombinant human chorionic gonadotropin (r-hCG). Recombinant fertility drugs are made in a laboratory using DNA technology. They are molecularly similar to hormones made by the body. In the case of r-hCG, the lab-made hormone is similar to the body's natural luteinizing hormone (LH).
What hormone is injected before ovulation?
Ovidrel (injected r-hCG) acts very similar to the body's luteinizing hormone (LH) that spikes just before ovulation. 1 The role of LH in the female reproductive system is to stimulate the maturing egg (still in its follicle in the ovary) to complete the stages of growth just before ovulation. Typically, there is a surge of LH about 36 hours before the follicle releases the egg.
Is ovarian hyperstimulation syndrome a risk for fertility drugs?
Whenever fertility drugs are used, there is a risk of developing ovarian hyperstimulation syndrome (OHSS). 3 OHSS is more often related to the use of gonadotropins along with Ovidrel, than from taking Ovidrel by itself.
Can you take ovidrel on its own?
Exactly when you take Ovidrel will partially depend on whether it’s being used on its own, alongside Clomid, with gonadotropins, as part of an IUI cycle, or as part of an IVF cycle. However, the general usage of Ovidrel is similar regardless of the fertility treatment protocol.
Can you use Ovidrel for PCOS?
However, this doesn’t necessarily mean you can’t use Ovidrel. In fact, Ovidrel is frequently used in fertility treatment cycles for women with PCOS. 3 Talk to your doctor if you have concerns.
When to give ovidrel?
Ovidrel (choriogonadotropin alfa) must be given at a very specific time in your menstrual cycle in order to work. Follow your provider's instructions about when to give yourself the injection very carefully.
How long is ovidrel good for?
If you choose to keep Ovidrel (choriogonadotropin alfa) at room temperature, it will only be good for 30 days. If you choose to keep it in the refrigerator, it will be good until the date marked on the box by the manufacturer.
What are the side effects of Ovidrel (choriogonadotropin alfa)?
With any medication, there are risks and benefits. Even if the medication is working, you may experience some unwanted side effects.
How much does Ovidrel (choriogonadotropin alfa) cost?
There is currently no generic for Ovidrel (choriogonadotropin alfa), so it can be expensive, even with insurance. GoodRx coupons, copay cards and patient assistance programs may help lower the cost.
How to treat tenderness after ovidrel injection?
After Ovidrel (choriogonadotropin alfa) has been injected, place a cotton ball over the area, and apply some pressure for several seconds. To prevent tenderness, gently massage the area while applying pressure.
How long does it take for ovidrel to ovulate?
It typically takes about 36 hours to ovulate after injecting Ovidrel (choriogonadotropin alfa). Since it is such a time-sensitive medication, you might be instructed to inject yourself at an unusual time if you are going to be having an egg retrieval done.
How to wash hands before injecting ovidrel?
Always wash your hands with soap and water before injecting Ovidrel (choriogonadotropin alfa), and make sure to wipe the area of skin you are going to inject the medication into with an alcohol swab before injecting.
How many studies have been done on Ovidrel?
The safety and efficacy of Ovidrel® have been examined in three well-controlled studies in women; two studies for assisted reproductive technologies (ART) and one study for ovulation induction (OI).
What is ovidrel prefilled syringe?
Ovidrel® PreFilled Syringe (choriogonadotropin alfa injection) is indicated for the induction of final follicular maturation and early luteinization in infertile women who have undergone pituitary desensitization and who have been appropriately pretreated with follicle stimulating hormones as part of an Assisted Reproductive Technology (ART) program such as in vitro fertilization and embryo transfer. Ovidrel® PreFilled Syringe is also indicated for the induction of ovulation (OI) and pregnancy in anovulatory infertile patients in whom the cause of infertility is functional and not due to primary ovarian failure.
How to stop bleeding from a syringe?
If any bleeding occurs, apply gentle pressure. If bleeding does not stop within a few minutes, place a clean piece of gauze over the injection site and cover it with an adhesive bandage.
What are the symptoms of OHSS?
It is characterized by an apparent dramatic increase in vascular permeability which can result in a rapid accumulation of fluid in the peritoneal cavity, thorax, and potentially, the pericardium. The early warning signs of development of OHSS are severe pelvic pain, nausea, vomiting, and weight gain. The following symptomatology has been seen with cases of OHSS: abdominal pain, abdominal distension, gastrointestinal symptoms including nausea, vomiting and diarrhea, severe ovarian enlargement, weight gain, dyspnea, and oliguria. Clinical evaluation may reveal hypovolemia, hemoconcentration, electrolyte imbalances, ascites, hemoperitoneum, pleural effusions, hydrothorax, acute pulmonary distress, and thromboembolic events (see “Pulmonary and Vascular Complications”). Transient liver function test abnormalities suggestive of hepatic dysfunction, which may be accompanied by morphologic changes on liver biopsy, have been reported in association with Ovarian Hyperstimulation Syndrome (OHSS).
How long does it take for ovarian enlargement to regress?
Mild to moderate uncomplicated ovarian enlargement which may be accompanied by abdominal distention and/or abdominal pain may occur in patients treated with FSH and hCG, and generally regresses without treatment within two or three weeks. Careful monitoring of ovarian response can further minimize the risk of overstimulation.
Does Ovidrel increase androstenedione?
In female subjects on oral contraception after an initial latency period, Ovidrel® induced a clear increase in androstenedione serum levels by 24 hours after dosing. Pharmacodynamic studies in females determined that the relationship of Ovidrel® pharmacokinetics to pharmacologic effect of Ovidrel® are complex and vary with the pharmacodynamic marker examined. In general pharmacologic effects are not proportional to exposure and in some cases appear to be near maximal at a 250 μg dose.
Important Note
- The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug. CHORIOGONADOTROPIN ALFA - INJECTABLE (k…
Uses
- This medication is used to help women with fertility problems become pregnant. It works by helping to produce mature eggs for fertilization; either naturally or by assisted means (e.g., in vitro fertilization).
How to Use
- Learn all preparation and usage instructions in the product package. If any of the information is unclear, consult your doctor or pharmacist. After injecting the mixing liquid (diluent) into the vial of powdered drug, gently roll the vial until the powder is completely dissolved; do not shake the injection/vial. Doing so may make this medicine ineffective. Inject this medication under the ski…
Side Effects
- Injection site reactions (e.g., pain, irritation, bruising, swelling), nausea, gas or vomiting may occur. If any of these effects persist or worsen, notify your doctor promptly. Tell your doctor immediately if any of these serious side effects occur: severe stomach/abdominal pain and/or swelling, unusual vaginal bleeding, diarrhea, weight gain, tro...
Precautions
- This medication is not recommended for use if you have the following medical conditions: primary ovarian failure, thyroid or adrenal gland problems, pituitary gland tumor, unusual vaginal bleeding, ovarian cysts, tumors or cancers of the female reproductive organs (e.g., fallopian tubes, ovaries, uterus). Tell your doctor your medical history, especially of: liver problems, any allergies…
Drug Interactions
- Tell your doctor of all prescription and nonprescription medication you may use. This product can affect the results of certain lab tests (e.g., hormone levels, pregnancy tests). Make sure laboratory personnel know you use this product. Do not start or stop any medicine without doctor or pharmacist approval.
Notes
- Do not share this medication with others. Laboratory and/or medical tests (e.g., hormone levels, ultrasound) may be performed to monitor your progress. Keep all scheduled doctor's appointments and medical exams.
Storage
- Before mixing, store at room temperature or in a refrigerator between 36 and 77 degrees F (2 and 25 degrees C) away from light. Once mixed, the vial must be used immediately. Discard any unused portion of the vial.