Full Answer
How is pomalidomide distributed in the US?
In order to decrease the risk of embryo-fetal exposure, pomalidomide is available only through a restricted distribution program ( Pomalyst REMS) and is dispensed by a specialty pharmacy enrolled in the R.E.M.S. Program Pomalidomide is given for 3 consecutive weeks, followed by one week off, for a 28-day Cycle.
Can you take pomalidomide while breastfeeding?
Lactation: There is no information regarding the presence of pomalidomide or elotuzumab in human milk, the effects of POMALYST or EMPLICITI on the breastfed child, or the effects of POMALYST on milk production. Pomalidomide was excreted in the milk of lactating rats.
What does pomalidomide do to multiple myeloma cells?
It is designed to kill or slow the growth of myeloma cells. Goals of therapy: Pomalidomide is given to decrease symptoms and slow the progression of multiple myeloma. It is not commonly given with the goal of cure.
How long do you have to take pomalidomide for?
Pomalidomide is given for 3 consecutive weeks, followed by one week off, for a 28-day Cycle. Typically, therapy with pomalidomide is continued until the drug no longer works or unacceptable toxicity is experienced. Tap along the timeline to move to different parts of the audio file.
Can you drink alcohol with POMALYST?
Do not combine this medication with other medications that can cause dizziness and confusion. Do not drink alcohol while taking this medication.
How long can you take POMALYST?
Dosage for Kaposi sarcoma The usual dose of Pomalyst to treat Kaposi sarcoma (KS) is 5 mg once a day. You'll likely take this dose on days 1 through 21 of your 28 day treatment cycle. Your doctor may have you stop taking Pomalyst if your KS gets worse or if side effects become too bothersome.
Does Bristol Myers Squibb have a patient assistance program?
The Bristol Myers Squibb Patient Assistance Foundation (BMSPAF) is an independent, charitable organization that helps eligible patients who need temporary help obtaining the medicines listed on this website.
What is the difference between Revlimid and POMALYST?
Pomalyst, also known as pomalidomide, is an oral immunomodulatory agent (IMiD) that is similar to Revlimid (lenalidomide, Celgene) and Thalomid (thalidomide, Celgene) but is more potent. Pomalyst is manufactured by Celgene.
When do you stop Pomalyst?
POMALYST with dexamethasone is intended to be used until your MM relapses or worsens. Your doctor may tell you to stop taking POMALYST if you develop certain serious side effects.
What is the cost of Pomalyst?
The cost for Pomalyst oral capsule 1 mg is around $20,983 for a supply of 21 capsules, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans. This Pomalyst price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
How do I get eliquis for $10 a month?
Eligible patients who present an activated Co-pay Card together with a valid prescription for ELIQUIS at participating pharmacies may pay as little as $10 per 30-day supply (up to 74 tablets for the first fill and up to 60 tablets for all subsequent fills) for up to 24 months, subject to a maximum annual benefit of ...
How do I get financial help from eliquis?
Call Tap to call 1-855-ELIQUIS (354-7847) from Monday – Friday, 8 AM – 8 PM (ET). Live specialists are here to: Help you find out if ELIQUIS is covered by your insurance plan. Determine if you are eligible for assistance paying for ELIQUIS.
Is eliquis made by Pfizer?
Blood thinner Eliquis has been a major growth driver for Bristol-Myers Squibb and partner Pfizer, as well as the overall biopharma sector.
Can you live 20 years with multiple myeloma?
While multiple myeloma doesn't yet have a cure and can be fatal, patients' life expectancies vary widely, according to Jens Hillengass, MD, Chief of Myeloma at Roswell Park Comprehensive Cancer Center. “I have seen patients live from several weeks to more than 20 years after being diagnosed,” Dr. Hillengass says.
What is the longest survival rate for myeloma?
Survival rates tell you what percentage of people with the same type and stage of cancer are still alive a certain amount of time (usually 5 years) after they were diagnosed....5-year relative survival rates for myeloma.SEER stage5-year relative survival rateDistant (multiple myeloma)55%All SEER stages combined56%2 more rows•Mar 2, 2022
Does Pomalyst make you tired?
Fatigue is a common side effect of treatment with POMALYST with dexamethasone. Sometimes people describe fatigue as feeling tired, weak, exhausted, heavy, or slow. Fatigue can affect people physically, mentally, and emotionally. If you feel tired, tell your doctor or nurse.
Does multiple myeloma always come back?
Statistics. According to the International Myeloma Foundation (IMF), myeloma relapse is common. Most people will have several remissions and relapses throughout the course of their condition. In people with no additional risk factors, the first period of remission may last for 2–3 years or longer.
Does Pomalyst cause neuropathy?
Common side effects of Pomalyst include: anemia, anxiety, confusion, dizziness, neuropathy, neutropenia, peripheral neuropathy, and thrombocytopenia. Other side effects include: acute myocardial infarction, cerebrovascular accident, and febrile neutropenia. See below for a comprehensive list of adverse effects.
What happens if multiple myeloma comes back?
If your doctor tells you that you're having a relapse, it means your multiple myeloma came back after your treatment left you cancer-free for a while. If this happens to you, keep in mind that there are still treatments that can help. It's a matter of finding the drug or combination of drugs that works for you.
Is Pomalyst chemo?
Pomalyst® is the trade name for the generic chemotherapy drug pomalidomide. In some cases, health care professionals may use the generic drug name pomalidomide when referring to the trade name drug Pomalyst®.
What do you need to know before taking pomalyst?
Before you begin taking POMALYST, you must read and agree to all of the instructions in the POMALYST REMS®program. Before prescribing POMALYST, your healthcare provider (HCP) will explain the POMALYST REMS program to you and have you sign the Patient-Physician Agreement Form.
What to tell HCP about hemodialysis?
If you have kidney problems and are receiving hemodialysis treatment. Tell your HCP about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. POMALYST and other medicines may affect each other, causing serious side effects.
Is a POMALYST a cost?
For qualified patients who are uninsured or underinsured, POMALYST may be available at no cost.
Is pomalyst safe for children?
POMALYST is a prescription medicine, taken along with the medicine dexamethasone, used to treat adults with multiple myeloma who have previously received at least 2 medicines to treat multiple myeloma, including a proteasome inhibitor and lenalidomide, and whose disease has become worse during treatment or within 60 days of finishing the last treatment. It is not known if POMALYST is safe and effective in children.
Can you breastfeed with pomalyst?
If you smoke cigarettes (POMALYST may not work as well in people who smoke), have any other medical conditions, or are breastfeeding. Do not breastfeed during treatment with POMALYST—it is not known if POMALYST passes into breast milk and can harm the baby. If you have liver problems.
Can you donate sperm while taking pomalyst?
Do not donate sperm while taking POMALYST, during any breaks (interruptions) in your treatment, and for 4 weeks after stopping POMALYST. If a female becomes pregnant with your sperm, the baby may be exposed to POMALYST and may be born with birth defects.
Can you use condoms while taking pomalyst?
Males, including those who have had a vasectomy, must always use a latex or synthetic condom during any sexual contact with a pregnant female or a female that can become pregnant while taking POMALYST, during any breaks (interruptions) in your treatment with POMALYST, and for 4 weeks after stopping POMALYST.
Appeals Assistance
If the patient's insurer has denied coverage, the denial may be appealed. BMS Access Support may be able to assist by providing information about the appeals process.
Identification of Charitable Organizations
BMS Access Support may help to identify charitable organizations that may provide funding for eligible patients seeking financial assistance for prescription medication.
How to contact POMALYST?
Your experience could help inspire fellow patients, caregivers, and healthcare professionals. To contact us, call 1‑800‑657‑9801 or email [email protected].
What do you need to know before taking pomalyst?
Before you begin taking POMALYST, you must read and agree to all of the instructions in the POMALYST REMS ® program. Before prescribing POMALYST, your healthcare provider (HCP) will explain the POMALYST REMS program to you and have you sign the Patient-Physician Agreement Form.
What to tell HCP about hemodialysis?
If you have kidney problems and are receiving hemodialysis treatment. Tell your HCP about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. POMALYST and other medicines may affect each other, causing serious side effects.
What is my momentum program?
VO: The My Momentum program provides support that may help you with your multiple myeloma journey.
Does POMALYST help with blood clots?
Most people who take POMALYST will also take a blood thinner medicine to help prevent blood clots.
Can you donate blood while taking pomalyst?
Do not donate blood while you take POMALYST, during any breaks (interruptions) in your treatment, and for 4 weeks after stopping POMALYST. If someone who is pregnant gets your donated blood, her baby may be exposed to POMALYST and may be born with birth defects.
Can you use condoms while taking pomalyst?
Males, including those who have had a vasectomy, must always use a latex or synthetic condom during any sexual contact with a pregnant female or a female that can become pregnant while taking POMALYST, during any breaks (interruptions) in your treatment with POMALYST, and for 4 weeks after stopping POMALYST.
What is the drug class for kaposi's sarcoma?
Pomalyst (pomalidomide) is a member of the miscellaneous antineoplastics drug class and is commonly used for Kaposi's Sarcoma, and Multiple Myeloma.
How much does a free drug card save?
The free Drugs.com Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions.
Is Pomalyst a generic?
Pomalyst is available as a brand name drug only, a generic version is not yet available. For more information, read about generic Pomalyst availability . This Pomalyst price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
What is the most common adverse reaction to POMALYST?
Hematologic Toxicity: Neutropenia (46%) was the most frequently reported Grade 3 or 4 adverse reaction in patients taking POMALYST in clinical trials, followed by anemia and thrombocytopenia. Monitor complete blood counts weekly for the first 8 weeks and monthly thereafter. Patients may require dose interruption and/or modification.
What is the grade of confusional state in POMALYST?
Dizziness and Confusional State: In patients taking POMALYST in clinical trials, 14% experienced dizziness (1% Grade 3 or 4) and 7% a confusional state (3% Grade 3 or 4). Instruct patients to avoid situations where dizziness or confusional state may be a problem and not to take other medications that may cause dizziness or confusional state without adequate medical advice.
What is the treatment for multiple myeloma?
POMALYST + dexamethasone + is atuximab-irfc is indicated for the treatment of adult patients with multiple myeloma who have received at least two prior therapies including lenalidomide and a proteasome inhibitor.
What to do if a grade 2 infusion reaction occurs?
If a Grade 2 or higher infusion reaction occurs, interrupt the EMPLICITI infusion and institute appropriate medical and supportive measures. If the infusion reaction recurs, stop the EMPLICITI infusion and do not restart it on that day. Severe infusion reactions may require permanent discontinuation of EMPLICITI therapy and emergency treatment.
What is a DVT in POMALYST?
Deep venous thrombosis (DVT), pulmonary embolism (PE), myocardial infarction, and stroke occur in patients with multiple myeloma treated with POMALYST. Prophylactic antithrombotic measures were employed in clinical trials. Thromboprophylaxis is recommended, and the choice of regimen should be based on assessment of the patient’s underlying risk factors.
Is Daratumumab contraindicated?
Daratumumab is contraindicated in patients with a history of severe hypersensitivity (e.g., anaphylactic reactions) to daratumumab or any of the components of the formulation.
Can you donate blood during a period of POMALYST?
Blood Donation: Patients must not donate blood during treatment with POMALYST and for 4 weeks following discontinuation of POMALYST therapy because the blood might be given to a pregnant female patient whose fetus must not be exposed to POMALYST.
How many days does a patient take a POMALYST?
Patients in the POMALYST + low-dose dexamethasone arm received 4 mg of POMALYST orally on Days 1 to 21 of 28-day cycles with 40 mg of dexamethasone once daily on specified days in the cycle, as seen here Patients in the high-dose dexamethasone arm received 40 mg of dexamethasone once daily on specified days in each 28-day cycle, as seen here.
What is a DVT in POMALYST?
Deep venous thrombosis (DVT), pulmonary embolism (PE), myocardial infarction, and stroke occur in patients with multiple myeloma treated with POMALYST. Prophylactic antithrombotic measures were employed in clinical trials. Thromboprophylaxis is recommended, and the choice of regimen should be based on assessment of the patient’s underlying risk factors.
What is the primary endpoint of the Phase 2 study?
Patients were randomized to receive either the triplet regimen or the doublet. The primary endpoint was PFS , and secondary endpoints were overall response rate, or ORR, and OS, all of which were investigator-assessed.
What percentage of proteasome inhibitors are refractory to both?
80% were refractory to a proteasome inhibitor, and 70% were refractory to both.
What premeds are needed for elotuzumab?
Prior to elotuzumab infusion, premedication with dexamethasone, antihistamines including H1 and H2 blockers, and acetaminophen was required.
What percentage of patients treated with triplets had grade 3/4 infections?
Sixty-five percent of patients treated in either arm experienced infections of any grade. Grade 3/4 infections were reported in 13% of patients treated with the triplet vs 22% with the doublet. Infusion reactions were reported in 3.3% of patients treated with the triplet.
How long were patients treated in the trial?
Patients in the trial were treated until disease progression or unacceptable toxicity.
Why is pomalidomide given?
Pomalidomide is given to decrease symptoms and slow the progression of multiple myeloma. It is not commonly given with the goal of cure. Tap along the timeline to move to different parts of the audio file.
What percentage of pomalidomide side effects are low white blood cells?
In clinical studies, the most commonly reported side effects with pomalidomide are shown here. Side effects sometimes have percentage ranges [example: 41 – 65% have low white blood cells] because they differed between clinical studies:
How long does pomalidomide last?
Typically, therapy with pomalidomide is continued until the drug no longer works or unacceptable toxicity is experienced. Tap along the timeline to move to different parts of the audio file.
How to minimize the cost of cancer treatment?
One way to minimize costs associated with cancer treatment is to ask your doctor what types of tests they are ordering. If they are expensive, ask if they are covered by insurance before getting the test. If you are concerned about costs, you can also ask your doctor to only order tests that are absolutely necessary and to minimize the ones that are unlikely to change the plan. Some anti-cancer and supportive care medications are now available as generic formulations and preferred by insurance companies. If these medications are still expensive, ask your doctor to work with your pharmacist to find cheaper alternatives. Some drugs have co-pay cards or patient assistance programs that can help reduce the cost.
Why do people discontinue pomalidomide?
On average, 2% - 9% of patients discontinue pomalidomide due to unacceptable side effects.
Where to speak with a patient assistance technician?
Ask to speak with a patient assistance technician or financial counselor at the clinic or hospital administering this therapy.
Who treats rare cancer?
Common cancer types, for which treatment is well-established, are often treated by both community cancer doctors and doctors working at large specialized cancer centers. For some very rare cancer types, it may be best to seek care from someone who specializes in treating them because they have more experience and may be able to offer clinical trials using newer and possibly more effective treatments.
Prior Authorization Assistance
- BMS Access Support can provide information about the prior authorization (PA) process. A Patient Access Specialist can: 1. Conduct a Benefits Review, obtaining information about any PA requirement 2. Call the payer to obtain PA details 3. Fax summary of benefits to provider Start a Benefits Review or Schedule a Callwith a Patient Access Specialist.
Appeals Assistance
- If the patient's insurer has denied coverage, the denial may be appealed. BMS Access Support may be able to assist by providing information about the appeals process.
- Each plan has its own process and timeline for appeals. It is important to review the insurer's guidelines and submit the required documents and information before the appeal deadline. It is the re...
Patient Financial Assistance
- For commercially insured patients 1. BMS co-pay assistance support programs provide financial assistance with out-of-pocket deductibles, co-pay, or co-insurance costs for eligible patients who have been prescribed certain BMS medications. Learn More > For patients with insurance through federal healthcare programs 1. Patients insured through Federal Healthcare Programs are not el…
Identification of Charitable Organizations
- BMS Access Support may help to identify charitable organizations that may provide funding for eligible patients seeking financial assistance for prescription medication. Search Organizations >