Why is remodulin used in PAH?
In patients with PAH requiring transition from epoprostenol, Remodulin is indicated to diminish the rate of clinical deterioration. Consider the risks and benefits of each drug prior to transition.
When is remodulin dosage adjustment necessary?
Remodulin dosage adjustment may be necessary if inhibitors or inducers of CYP2C8 are added or withdrawn.
How do my patients enroll in this program?
Your patients must be 18 years or older and understand and agree to comply with the eligibility requirements and terms of use.
What are the side effects of SC remodulin?
In clinical studies of SC Remodulin infusion, the most common adverse events reported were infusion site pain and infusion site reaction (redness, swelling, and rash). These symptoms were sometimes severe and sometimes required treatment with narcotics or discontinuation of Remodulin. The IV infusion of Remodulin with an external infusion pump has been associated with a risk of blood stream infections, arm swelling, paresthesias, hematoma, and pain. Other common adverse events (≥3% more than placebo) seen with either SC or IV Remodulin were headache (27% vs. 23%), diarrhea (25% vs. 16%), nausea (22% vs. 18%), rash (14% vs. 11%), jaw pain (13% vs. 5%), vasodilatation (11% vs. 5%), edema (9% vs. 3%), and hypotension (4% vs. 2%).
What is remodulin iassist?
Remodulin is simplifying the referral process with iAssist, a centralized hub that helps initiate and facilitate the referral process for you and your patients. At no cost to you, treatment with Remodulin now comes with a streamlined solution that includes:
How much does United Therapeutics pay for remodulin?
The Remodulin Co-Pay Assistance Program, offered through United Therapeutics, allows most eligible patients who enroll to pay as little as a $5 co-pay for each prescription—up to $8000 savings per year.
Does remodulin increase bleeding?
Remodulin inhibits platelet aggregation and increases the risk of bleeding.
Remodulin Co-Pay Assistance Card
If you have a commercial or private insurance plan, we offer a co-pay assistance card to help cover some of your out-of-pocket expenses.
Patient Assistance Program (PAP)
United Therapeutics offers a free medication program for uninsured and underinsured patients who meet eligibility requirements.
Other financial support resources
There are independent Patient Assistance Programs* available that offer financial assistance to PAH patients in need. Known patient assistance programs that support PAH are listed below, in no particular order.
What is Remodulin?
Remodulin is a prescription medication used to treat adults with pulmonary arterial hypertension (PAH; WHO Group 1), which is high blood pressure in the arteries of your lungs. Remodulin can reduce symptoms associated with exercise. Remodulin was studied mainly in patients with NYHA Functional Class II-IV symptoms.
What is remodulin used for?
Remodulin is a prescription medication used to treat adults with pulmonary arterial hypertension (PAH; WHO Group 1), which is high blood pressure in the arteries of your lungs. Remodulin can reduce symptoms associated with exercise. Remodulin was studied mainly in patients with NYHA Functional Class II-IV symptoms.
How to learn more about Remodulin?
To learn more about Remodulin, talk with your healthcare provider. Please see Full Prescribing Information at www.remodulin.com or call Customer Service at 1-877-UNITHER (1-877-864-8437).
What to tell your healthcare provider before taking Remodulin?
Before you take Remodulin, tell your healthcare provider if you: Have other medical conditions or take other medicines that may affect your use of Remodulin by increasing the risk of side effects or decreasing the drug’s effectiveness. Have liver or kidney problems.
Can remodulin be adjusted?
Have liver or kidney problems. Your Remodulin dose may need to be adjusted if you have liver problems.
Is remodulin IV or IV?
Continuous intravenous (IV) infusions of Remodulin delivered using an external infusion pump, with a tube placed in a central vein within the chest, are associated with the risk of blood stream infections and sepsis, which may be fatal. Therefore, continuous subcutaneous (SC) infusion delivered just beneath the skin is the preferred type of delivery.
Does remodulin cause arm swelling?
IV infusion of Re modulin delivered through an external pump has been associated with the risk of blood stream infections, arm swelling, tingling sensations, bruising, and pain.
Where to report side effects?
Call your doctor for medical advice about side effects. You may report side effects to the FDA at www.fda.gov/MedWatch or call 1-800-FDA-1088. The risk information provided here is not comprehensive.
What is remodulin used for?
Remodulin is a prescription medication used to treat adults with pulmonary arterial hypertension (PAH; WHO Group 1), which is high blood pressure in the arteries of your lungs. Remodulin can reduce symptoms associated with exercise. Remodulin was studied mainly in patients with NYHA Functional Class II-IV symptoms.
How to learn more about Remodulin?
To learn more about Remodulin, talk with your healthcare provider. Please see Full Prescribing Information at www.remodulin.com or call Customer Service at 1-877-UNITHER (1-877-864-8437). PAH=pulmonary arterial hypertension; WHO=World Health Organization.
What to tell your healthcare provider before taking Remodulin?
Before you take Remodulin, tell your healthcare provider if you: Have other medical conditions or take other medicines that may affect your use of Remodulin by increasing the risk of side effects or decreasing the drug’s effectiveness.
Can remodulin harm a baby?
Are pregnant, breastfeeding, or planning to become pregnant. It is not known if Remodulin will harm your unborn baby or if Remodulin passes into your breast milk.
Is remodulin IV or IV?
Continuous intravenous (IV) infusions of Remodulin delivered using an external infusion pump, with a tube placed in a central vein within the chest, are associated with the risk of blood stream infections and sepsis, which may be fatal. Therefore, continuous subcutaneous (SC) infusion delivered just beneath the skin is the preferred type of delivery.
Where to report remodulin side effects?
Call your doctor for medical advice about side effects. You may report side effects to the FDA at www.fda.gov/MedWatch or call 1-800-FDA-1088. The risk information provided here is not comprehensive.
Can you stop taking Remodulin?
Do not stop taking or greatly reduce your Remodulin dose without consulting your doctor. Low blood pressure (symptomatic hypotension). If you have low blood pressure or are taking drugs that lower your blood pressure, the risk of low blood pressure is increased.
Important Note
The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.
Uses
This medication is used to treat a type of high blood pressure in the lungs (pulmonary arterial hypertension). It works by causing the blood vessels (arteries) in the lungs to relax and expand, thus decreasing the pressure.
Drug Interactions
Tell your doctor of all prescription and nonprescription medication you may use, especially: "water pills" (e.g., furosemide, torsemide), "blood thinners" (e.g., warfarin, heparins), blood pressure medication (e.g., captopril, lisinopril, nifedipine), vasodilators (e.g., hydralazine, nitrates), digoxin.
Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include: severe dizziness, fainting.
Notes
Do not share this medication with others. Laboratory and/or medical tests (e.g., blood pressure, heart rate, heart function) will be performed to monitor your progress and response to this medication.
Missed Dose
This drug is to be given continuously into the skin. If your dose is interrupted, contact your doctor or pharmacist immediately to establish new dosing.
Storage
Store unopened vials at room temperature between 59 and 77 degrees F (15 to 25 degrees C) away from light and moisture. Brief storage at 59 to 86 degrees F (15-30 degrees C) is permitted. Do not freeze. Consult your pharmacist for details regarding the stability of the drug after the vial has been opened.
What is remodulin used for?
Remodulin (treprostinil) is a member of the agents for pulmonary hypertension drug class and is commonly used for Pulmonary Hypertension.
How much does a free drug card save?
The free Drugs.com Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions.
Is remodulin generic?
A generic version of Remodulin is available, see treprostinil prices.
What to tell your healthcare provider before taking Remodulin?
Before you take Remodulin, tell your healthcare provider if you: Have other medical conditions or take other medicines that may affect your use of Remodulin by increasing the risk of side effects or decreasing the drug’s effectiveness.
Does remodulin cause blood pressure to increase?
Bleeding problems. Remodulin may increase the risk of bleed ing in people who take blood thinners (anticoagulants).
Is remodulin IV or IV?
Continuous intravenous (IV) infusions of Remodulin delivered using an external infusion pump, with a tube placed in a central vein within the chest, are associated with the risk of blood stream infections and sepsis, which may be fatal. Therefore, continuous subcutaneous (SC) infusion delivered just beneath the skin is the preferred type of delivery.
Can remodulin harm a baby?
Are pregnant, breastfeeding, or planning to become pregnant. It is not known if Remodulin will harm your unborn baby or if Remodulin passes into your breast milk.
Does remodulin cause rash?
These are not all the possible side effects of Remodulin.
Is remodulin safe for children?
Remodulin was studied mainly in patients with NYHA Functional Class II-IV symptoms. It is not known if Remodulin is safe and effective in children. In people with PAH who need to switch from epoprostenol, Remodulin is approved to slow the worsening of symptoms.
Remodulin Co-Pay Assistance Card
For patients with commercial or private insurance plans, we offer a co-pay card to help patients cover some of their out-of-pocket expenses.
Patient Assistance Program (PAP) for uninsured or underinsured patients
If your patient does not have insurance, their insurance does not cover the medication, or they are underinsured, United Therapeutics offers medication free of charge to eligible patients. Please contact ASSIST to check your patient’s eligibility.
Important Reminder
Please remind your patients to keep the Specialty Pharmacy informed about their current insurance status.
Indication
Remodulin is a prostacyclin vasodilator indicated for the treatment of pulmonary arterial hypertension (PAH; WHO Group 1) to diminish symptoms associated with exercise.
Important Safety Information for Remodulin
Chronic intravenous (IV) infusions of Remodulin delivered using an external infusion pump with an indwelling central venous catheter are associated with the risk of blood stream infections (BSI) and sepsis, which may be fatal. Therefore, continuous subcutaneous (SC) infusion is the preferred mode of administration.