What is Revlimid used to treat?
REVLIMID ® (lenalidomide) in combination with dexamethasone (dex) is indicated for the treatment of adult patients with multiple myeloma (MM). REVLIMID is indicated as maintenance therapy in adult patients with MM following autologous hematopoietic stem cell transplantation (auto-HSCT).
How can I find financial assistance for patients with Revlimid?
BMS Access Support ® can help identify financial assistance programs for eligible patients who have been prescribed REVLIMID and who need help managing the cost of treatment. The appropriate program will depend on the patient’s coverage.
Is Revlimid covered by insurance?
Depending on your patient’s insurance situation, there are programs and organizations that may help for REVLIMID. For eligible patients with commercial or private insurance (including healthcare exchanges),* co-pay responsibility for REVLIMID is reduced to $25 (subject to annual benefit limit).
What should I know before taking Revlimid?
Your healthcare provider will check you for new cancers during your treatment with REVLIMID. Severe liver problems, including liver failure and death. Your healthcare provider should do blood tests to check your liver function during your treatment with REVLIMID.
Is Revlimid considered chemotherapy?
Revlimid | Chemotherapy Drug Information | Chemocare.com.
How long does Revlimid stay in your system?
Revlimid stays in your system for up to 4 weeks after stopping treatment. So it's possible that you could still experience side effects of the drug after your last dose.
How do you get Revlimid?
REVLIMID is only available through a select network of specialty pharmacies due to a restricted distribution program called Lenalidomide REMS. These specialty pharmacies help to manage the handling and shipping of REVLIMID and may provide additional resources.
Why does Revlimid cost so much?
Because Revlimid is an oral cancer treatment and not a chemotherapy infusion, it's covered by the drug plan of those with insurance. Myeloma patients will tend to hit their drug maximums quickly too, which means that they face no co-pays for the drug for much of the year. Even so, the costs can be significant.
What time of day is best to take Revlimid?
The tablets should be swallowed whole with water and needs to be taken on an empty stomach either one hour before or two hours after food. Lenalidomide can be taken at any time of the day but it is best to take it at approximately the same time each day.
What is the success rate of Revlimid?
Patients who took REVLIMID and dexamethasone continuously had a 75% response rate compared to 73% of patients who took REVLIMID and dexamethasone for only 18 months and 62% of patients who took the combination of melphalan, prednisone, and thalidomide.
What tier drug is REVLIMID?
What drug tier is Revlimid typically on? Medicare prescription drug plans typically list Revlimid on Tier 5 of their formulary. Generally, the higher the tier, the more you have to pay for the medication.
Is Generic REVLIMID available?
A generic for Revlimid is finally available. On March 7, 2022 Teva Pharmaceuticals released lenalidomide capsules, the generic version of Revlimid in the United States. They will come in strengths of 5mg, 10mg, 15mg and 25mg.
Who can prescribe REVLIMID?
To avoid embryo-fetal exposure, REVLIMID is only available under a restricted distribution program called "REVLIMID Risk Evaluation and Mitigation Strategy (REMS)." Only certified prescribers can prescribe REVLIMID and only certified pharmacies can dispense REVLIMID in the REVLIMID REMS® program.
What is the cost of Revlimid in USA?
Celgene launched Revlimid in 2005 at a price of $215 per pill. After more than 20 price hikes, the drug now costs $763 per pill, or $16,023 per month.
Does multiple myeloma affect your breathing?
Shortness of breath, also called dyspnea, is a common symptom of multiple myeloma, a type of cancer that forms in blood cells. Feeling like you can't catch your breath — or, in severe cases, feeling like you can't breathe at all — can be extremely worrying.
How do people cope with multiple myeloma?
Here are some tips for coping with multiple myeloma:Understand your diagnosis. ... Communicate openly with your treatment team. ... Find help to manage your symptoms. ... Report any side effects. ... Learn to relax your mind and body. ... Seek extra support.
What happens when you stop taking REVLIMID?
No, stopping Revlimid treatment doesn't cause withdrawal symptoms. Withdrawal symptoms weren't reported as a side effect in people taking the medication in clinical studies. But if you stop taking Revlimid, your condition could worsen. You could also experience more symptoms of the condition.
What does REVLIMID do to your body?
Treatment with REVLIMID can cause swelling of the limbs (arms, hands, and feet) and skin, called edema. This swelling or puffiness of the tissue directly under your skin is caused by excess fluid trapped in your body's tissues. Edema is most commonly noticed in the hands, arms, feet, ankles, and legs.
Does REVLIMID affect eyesight?
In 100 people receiving Velcade, Revlimid, Dexamethasone, from 4 to 20 may have: Cloudiness of the eye, visual disturbances.
What happens if you forget to take REVLIMID?
If you miss a dose of Revlimid, take the missed dose as soon as possible, up to 12 hours after your usual time. But if you miss your dose of Revlimid by 12 hours or more, skip that day's dose. Then, the next day, you should take Revlimid at your usual time. Don't take two doses to make up for a missed dose.
Financial assistance
Depending on your patient’s insurance situation, there are programs and organizations that may help for REVLIMID.
Insurance-related assistance
Our Specialists are available to assist with each of the following steps in the insurance approval process for REVLIMID. §
What is BMS Access Support?
BMS Access Support ® can help identify financial assistance programs for eligible patients who have been prescribed REVLIMID and who need help managing the cost of treatment. The appropriate program will depend on the patient’s coverage.
How much does BMS cost?
Eligible patients may pay as little as $10 per 30-day supply, up to a maximum of $15,000 per calendar year.
Does Bristol Myers Squibb provide free medical care?
The Bristol Myers Squibb Patient Assistance Foundation (BMSPAF), a charitable organization, may also provide medicine, free of charge, to eligible, uninsured patients who have an established financial hardship. For more information and eligibility criteria, visit bmspaf.org.
Does Bristol Myers Squibb guarantee reimbursement?
Bristol Myers Squibb cannot guarantee that a patient will receive assistance. The accurate completion of reimbursement- or coverage-related documentation is the responsibility of the healthcare provider and patient. Bristol Myers Squibb and its agents make no guarantee regarding reimbursement for any service or item.
What do you need to know before prescribing Revlimid?
Before you begin taking REVLIMID, you must read and agree to all of the instructions in the REVLIMID REMS ® program. Before prescribing REVLIMID, your healthcare provider will explain the REVLIMID REMS program to you and have you sign the Patient-Physician Agreement Form.
How to take Revlimid?
Take REVLIMID at about the same time each day. Do not open the REVLIMID capsules or handle them any more than needed. If powder from the. REV LIMID capsule comes in contact with: your skin, wash the skin right away with soap and water. inside of your eyes, nose, or mouth, flush well with water.
What is Revlimid used for?
REVLIMID ® (lenalidomide) is a prescription medicine, used to treat adults with multiple myeloma (MM) in combination with the medicine dexamethasone, or as maintenance treatment after autologous hematopoietic stem cell transplantation (a type of stem cell transplant that uses your own stem cells). REVLIMID should not be used to treat people who ...
How to contact Celgene?
If your healthcare provider is not available, you can call Celgene Customer Care Center at 1-888-423-5436. Healthcare providers and patients should report all cases of pregnancy to: FDA MedWatch at 1-800-FDA-1088, and. Celgene Corporation, a Bristol Myers Squibb company, at 1-888-423-5436.
What to tell your healthcare provider before taking Revlimid?
Before taking REVLIMID, tell your healthcare provider: if you have had a blood clot in the past; if you have high blood pressure, smoke, or if you have been told you have a high level of fat in your blood (hyperlipidemia); and. about all the medicines you take.
What are the symptoms of Revlimid?
Call your healthcare provider right away if you develop any of the following signs or symptoms during treatment with REVLIMID: a red, itchy, skin rash. peeling of your skin or blisters. severe itching. fever. Get emergency medical help right away if you develop any of the following signs or symptoms.
Does Revlimid cause heart attacks?
Heart attacks and strokes also happen more often in people who take REVLIMID with dexamethasone.
How BMS Access Support May Help
Find out how BMS can work with patients and their healthcare providers to help access a prescribed BMS medication.
Financial Support Options
There may be programs and services that could help with the cost of treatment. Learn about what options are available.
Additional Resources
We provide videos, tools, and other resources that may help with your access and reimbursement needs.
Available medicines
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How to apply
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Contraindications
Warnings and Precautions
- Embryo-Fetal Toxicity: See Boxed WARNINGS. 1. Females of Reproductive Potential: See Boxed WARNINGS. 2. Males: Lenalidomide is present in the semen of patients receiving the drug. Males must always use a latex or synthetic condom during any sexual contact with females of reproductive potential while taking REVLIMID and for up to 4 weeks after discontinuing REVLIMI…
Multiple Myeloma
- In newly diagnosed: The most frequently reported Grade 3 or 4 reactions included neutropenia, anemia, thrombocytopenia, pneumonia, asthenia, fatigue, back pain, hypokalemia, rash, cataract, lymphop...
- The most common adverse reactions reported in ≥20% (Arm Rd Continuous): diarrhea (45%), anemia (44%), neutropenia (35%), fatigue (33%), back pain (32%), asthenia (28%), insomnia (2…
- In newly diagnosed: The most frequently reported Grade 3 or 4 reactions included neutropenia, anemia, thrombocytopenia, pneumonia, asthenia, fatigue, back pain, hypokalemia, rash, cataract, lymphop...
- The most common adverse reactions reported in ≥20% (Arm Rd Continuous): diarrhea (45%), anemia (44%), neutropenia (35%), fatigue (33%), back pain (32%), asthenia (28%), insomnia (28%), rash (26%),...
- Maintenance Therapy Post Auto-HSCT:The most frequently reported Grade 3 or 4 reactions in ≥20% (REVLIMID arm) included neutropenia, thrombocytopenia, and leukopenia. The serious adverse reactions o...
- The most frequently reported adverse reactions in ≥20% (REVLIMID arm) across both mainte…
Drug Interactions
- Periodically monitor digoxin plasma levels due to increased Cmaxand AUC with concomitant REVLIMID therapy. Patients taking concomitant therapies such as ESAs or estrogen-containing therapies may have an increased risk of thrombosis. It is not known whether there is an interaction between dexamethasone and warfarin. Close monitoring of PT and INR is recommen…
Use in Specific Populations
- PREGNANCY: See Boxed WARNINGS:If pregnancy does occur during treatment, immediately discontinue the drug and refer patient to an obstetrician/gynecologist experienced in reproductive toxicity for f...
- LACTATION: There is no information regarding the presence of lenalidomide in human milk, the effects of REVLIMID on the breastfed infant, or the effects of REVLIMID on milk productio…
- PREGNANCY: See Boxed WARNINGS:If pregnancy does occur during treatment, immediately discontinue the drug and refer patient to an obstetrician/gynecologist experienced in reproductive toxicity for f...
- LACTATION: There is no information regarding the presence of lenalidomide in human milk, the effects of REVLIMID on the breastfed infant, or the effects of REVLIMID on milk production. Because many...
- RENAL IMPAIRMENT: Adjust the starting dose of REVLIMID based on creatinine clearance value and for patients on dialysis.