What is Rubraca used for?
What Warnings should I know about Rubraca?
What other important information should I know about Rubraca?
What other medications might interact with Rubraca?
About this website
Is Rubraca covered by Medicare?
Do Medicare prescription drug plans cover Rubraca? Yes. 100% of Medicare prescription drug plans cover this drug.
What is Rubraca used to treat?
What is Rubraca used for? Rubraca tablets are a prescription medicine used in adults for: the maintenance treatment of ovarian cancer, fallopian tube cancer, or primary peritoneal cancer whose cancer has come back and who are in response (complete or partial response) to a platinum-based chemotherapy.
Is Rubraca FDA approved?
Rubraca is the company's only commercial product. The FDA first approved the drug in December 2016 as a monotherapy for patients with deleterious BRCA mutation-associated advanced ovarian cancer who have been treated with two or more chemotherapies.
Is there a generic for Rubraca?
Has a generic version of Rubraca been approved? No. There is currently no therapeutically equivalent version of Rubraca available in the United States.
How long can you stay on Rubraca?
Duration of response: How long the patient's response to Rubraca lasted. Patients' response to treatment with Rubraca ranged from 1.7 to more than 24.0 months. More than half (15 of 27) of patients who responded had a confirmed response to treatment lasting longer than 6 months.
What are side effects of Rubraca?
Nausea/vomiting, diarrhea, constipation, stomach/abdominal pain, decreased appetite, metallic taste, or dizziness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
Is Veliparib FDA approved?
Veliparib does not yet have an approved label; nevertheless, there are currently promising results available in preclinical and early clinical settings. This comprehensive review summarizes the mechanism of action of veliparib and provides an overview of its early and ongoing clinical investigations.
Is Talazoparib FDA approved?
On October 16, 2018, the FDA approved talazoparib (Talzenna; Pfizer), an oral PARP inhibitor, for the treatment of adults with deleterious or suspected deleterious germline BRCA mutation–positive, HER2-negative locally advanced or metastatic breast cancer.
How effective is rucaparib?
Overall, the women who received rucaparib lived a longer time without their cancer progressing (progression-free survival) than women in the placebo group: 10.8 months, compared with 5.4 months. The benefit of rucaparib was stronger in patients with DNA repair defects, as measured by the companion diagnostic test.
How long can you take rucaparib?
When you have rucaparib. You usually start taking rucaparib 2 months after the last dose of platinum chemotherapy. You take it for as long as it is working and the side effects aren't too bad.
Is Rubraca a PARP inhibitor?
Rubraca is a PARP inhibitor. It travels through your body and targets cancer cells, preventing them from using this tool. This causes cancer cells to die. Cells with HRD and BRCA are easier for Rubraca to fight.
What type of medication is rucaparib?
Rucaparib is in a class of medications called poly (ADP-ribose) polymerase (PARP) inhibitors. It works by killing cancer cells.
Is Rubraca a good drug?
Effectiveness for ovarian cancer Clinical studies have shown that Rubraca is an effective treatment for ovarian cancer. One clinical study looked at adults whose ovarian cancer had returned and was responding to platinum-based chemotherapy. Rubraca was compared with a placebo (treatment with no active drug).
Are PARP inhibitors considered chemotherapy?
PARP inhibitors interfere with certain enzymes that help cancer cells repair. Blocking these enzymes allows the cancer cells to die. These inhibitors are targeted therapies — they target cancer cells and have less effect on healthy cells than traditional chemotherapy.
Is Rubraca a PARP inhibitor?
Rubraca is a PARP inhibitor. It travels through your body and targets cancer cells, preventing them from using this tool. This causes cancer cells to die. Cells with HRD and BRCA are easier for Rubraca to fight.
How long does Rucaparib take to work?
This is for 2 weeks following their vaccination.
What is Rubraca used for?
Rubraca ® (rucaparib) tablets are a prescription medicine used in adults for the treatment of castration-resistant prostate cancer (prostate cancer that no longer responds to medical or surgical treatment that lowers testosterone):
What Warnings should I know about Rubraca?
Rubraca tablets may cause serious side effects including bone marrow problems called Myelodysplastic Syndrome (MDS) or a type of cancer of the blood called A cute Myeloid Leukemia (AML). Some people who have ovarian cancer and who have received previous treatment with chemotherapy or certain other medicines for their cancer have developed MDS or AML during or after treatment with Rubraca, although MDS or AML was not observed in men with prostate cancer during the clinical study. MDS or AML may lead to death. If you develop MDS or AML, your healthcare provider will stop treatment with Rubraca.
What other important information should I know about Rubraca?
Your healthcare provider will do blood tests before, and every month during treatment with Rubraca to monitor your blood cell counts. Weekly blood tests will be performed if you have low blood cell counts for a long time. Your healthcare provider may stop treatment with Rubraca until your blood cell counts improve.
What are the side effects of Rubraca?
The most common side effects for men in Rubraca clinical studies were weakness/fatigue, nausea, decreased red blood cell count, changes in liver function tests, decreased appetite, constipation, rash, decreased platelet count, vomiting, and diarrhea.
What is Rubraca Connections?
Rubraca Connections is a personalized support program with live dedicated Access Specialists to answer your questions about starting, affording, and continuing your Rubraca
How long after Rubraca can you donate sperm?
If you are a male with a female partner who is pregnant or able to become pregnant, effective birth control should be used during treatment and for 3 months after the last dose of Rubraca. Do not donate sperm during use and for 3 months after the last dose of Rubraca.
How to contact Rubraca?
Rubraca Connections can support you in getting Rubraca and help you in navigating financial assistance. For more information, call 1-844-779-7707, Monday through Friday, 8 am to 8 pm ET, or visit www.RubracaConnections.com
Clovis Cares Personalized Practice Support
Your Practice Experience Manager helps ensure that Rubraca will be covered and that patients will receive it quickly and easily.
Clovis Cares QuickStart Program
Patients, regardless of income or insurance type (commercial/government), who experience a delay of 5 business days or more in starting Rubraca may receive the first 15 days of treatment at no cost, with up to 3 refills (maximum 60 days). †‡
What is the drug class of Rubraca?
Rubraca (rucaparib) is a member of the PARP inhibitors drug class and is commonly used for Ovarian Cancer, and Prostate Cancer.
How much does a free drug card save?
The free Drugs.com Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions.
Why is oral tablet important?
Oral Tablet. Important: When there is a range of pricing, consumers should normally expect to pay the lower price. However, due to stock shortages and other unknown variables we cannot provide any guarantee. Important: When there is a range of pricing, consumers should normally expect to pay the lower price.
Is Rubraca a generic?
Rubraca is available as a brand name drug only, a generic version is not yet available. For more information, read about generic Rubraca availability . This Rubraca price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
What is Rubraca used for?
Rubraca ® (rucaparib) tablets are a prescription medicine used in adults for the treatment of castration-resistant prostate cancer (prostate cancer that no longer responds to medical or surgical treatment that lowers testosterone):
What Warnings should I know about Rubraca?
Rubraca tablets may cause serious side effects including bone marrow problems called Myelodysplastic Syndrome (MDS) or a type of cancer of the blood called A cute Myeloid Leukemia (AML). Some people who have ovarian cancer and who have received previous treatment with chemotherapy or certain other medicines for their cancer have developed MDS or AML during or after treatment with Rubraca, although MDS or AML was not observed in men with prostate cancer during the clinical study. MDS or AML may lead to death. If you develop MDS or AML, your healthcare provider will stop treatment with Rubraca.
What other important information should I know about Rubraca?
Your healthcare provider will do blood tests before, and every month during treatment with Rubraca to monitor your blood cell counts. Weekly blood tests will be performed if you have low blood cell counts for a long time. Your healthcare provider may stop treatment with Rubraca until your blood cell counts improve.
What other medications might interact with Rubraca?
Tell your healthcare provider about all of your medical conditions and all medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
