Full Answer
What is selpercatinib used to treat?
Selpercatinib is also used to treat certain types of thyroid cancer in adults and children at least 12 years old. selpercatinib is used when the cancer has spread to other parts of the body (metastatic).
How much selpercatinib should I take for retevmo?
The recommended selpercatinib dose is weight based—120 mg for patients less than 50 kg, and 160 mg for those 50 kg or greater. Selpercatinib is taken orally twice daily with or without food; or with food when co-administered with a proton pump inhibitor. View full prescribing information for RETEVMO.
How should I take selpercatinib?
Use the medicine exactly as directed. Selpercatinib is usually taken every 12 hours. Take selpercatinib with food if you also use a "proton pump inhibitor" stomach acid medicine such as esomeprazole, lansoprazole, omeprazole, Prevacid, Prilosec, Nexium, and others.
What medications should I avoid while taking selpercatinib?
stomach acid medicines (such as cimetidine, famotidine, Axid, Pepcid, Tagamet, and others)--take selpercatinib dose 2 hours before or 10 hours after you take the other medicine. Other drugs may affect selpercatinib, including prescription and over-the-counter medicines, vitamins, and herbal products.
What is Selpercatinib used for?
Can you use alcohol with a medicine?
Is selpercatinib good for cancer?
Can you change the dose of Selpercatinib?
About this website
Does Eli Lilly have a patient assistance program?
Lilly Cares® Foundation Patient Assistance Program (Lilly Cares) is a nonprofit charitable organization that provides prescribed Lilly medications for free for up to 12 months to qualifying U.S. patients.
Is patient assistance program legitimate?
Patient assistance programs (PAPs) are usually sponsored by pharmaceutical manufacturers and are promoted as a safety net for Americans who have no health insurance or are underinsured.
Is Retevmo covered by insurance?
Do Medicare prescription drug plans cover Retevmo? Yes. 100% of Medicare prescription drug plans cover this drug.
What is Allergan patient assistance program?
The Allergan Patient Assistance Program (PAP) provides Allergan medicines at no cost to eligible patients. If the patient qualifies, up to a twelve-month eligibility for the requested medication(s) or device(s) is approved for shipment to the patient's licensed prescriber for dispensing.
How do you qualify for free eliquis?
You may be eligible for the Free 30-Day Trial Offer for ELIQUIS® (apixaban) if:You have not previously filled a prescription for ELIQUIS;You have a valid 30-day prescription for ELIQUIS;You are being treated with ELIQUIS for an FDA-approved indication that an HCP has planned for more than 35 days of treatment;More items...
How do patient support programs work?
A patient assistance or support programs (PAPs or PSPs) exist to get you timely access to medication and to help you stay on track of your therapy. Being diagnosed with a complex disease or condition may come with unexpected financial burden and a need to better understand treatment options and next steps.
What is the cost of Retevmo?
The cost for Retevmo oral capsule 80 mg is around $10,855 for a supply of 60 capsules, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
Does Medicare cover Selpercatinib?
Yes. 100% of Medicare prescription drug plans cover this drug.
Can you drink alcohol with Retevmo?
There are no known interactions between alcohol and Retevmo. However, it's possible that side effects of Retevmo may become worse from drinking alcohol during treatment. For example, Retevmo may cause liver problems to occur. Alcohol can also increase your risk of liver problems.
What is AbbVie Assistance Program?
Patient Assistance Application Overview myAbbVie Assist provides free medicine to qualifying patients. If you are uninsured or have limited insurance coverage, you may be eligible to receive prescribed AbbVie medication at no cost from our Program.
How do I contact AbbVie?
If you have questions, call us at 1-800-222-6885.
How does the pan foundation work?
What does PAN cover? Our 12-month grants offer financial assistance for out-of-pocket medication costs, including co-pays, health insurance premiums, and transportation costs associated with medical care. Co-pay funds: assistance with deductibles, co-pays, and coinsurance for medications.
What are the income limits for GSK patient assistance program?
You must also meet certain household income eligibility requirements as outlined below:48 States and DCHousehold SizeMaximum Monthly Gross Income1$2,831.252$3,814.583$4,797.924 more rows
Why do pharmaceutical companies have patient assistance programs?
They increase demand, allow companies to charge higher prices, and provide public-relations benefits. Assistance programs are an especially attractive proposition for firms that sell particularly costly drugs. Faced with high out-of-pocket costs, some patients may decide against taking an expensive medication.
Why are patient assistance programs important?
By providing financial assistance for hundreds of medications, PAPs provide a valuable resource to patients, helping them comply with recommended drug regimens and, in turn, obtain better health outcomes. Millions of Americans use PAPs to get the medicines they need but can't afford.
What is Selpercatinib used for?
Selpercatinib is used to treat metastatic (cancer that has already spread) non-small cell lung cancer (NSCLC) in patients whose tumors have RET fusion-positive genes. Your doctor will perform a test to check for the RET gene fusion before you use selpercatinib.
Can you use alcohol with a medicine?
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Is selpercatinib good for cancer?
Medicines used to treat cancer are very strong and can have many side effects. Before receiving selpercatinib, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
Can you change the dose of Selpercatinib?
The following information includes only the average doses of selpercatinib. If your dose is different, do not change it unless your doctor tells you to do so.
What is selpercatinib?
Selpercatinib is used to treat a certain type of non-small cell lung cancer in adults.
What other drugs will affect selpercatinib?
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
How long after taking a cimetidine can you take Selpercatinib?
stomach acid medicines (such as cimetidine, famotidine, Axid, Pepcid, Tagamet, and others)--take selpercatinib dose 2 hours before or 10 hours after you take the other medicine. Other drugs may affect selpercatinib, including prescription and over-the-counter medicines, vitamins, and herbal products.
Can you take Selpercatinib with food?
Take selpercatinib with food if you also use a "proton pump inhibitor" stomach acid medicine such as esomeprazole, lansoprazole, omeprazole, Prevacid, Prilosec, Nexium, and others. Follow your doctor's dosing instructions very carefully. If you vomit shortly after taking selpercatinib, do not take another dose.
Can you breastfeed with selpercatinib?
However, it is important to use birth control to prevent pregnancy because selpercatinib can harm an unborn baby. Do not breastfeed while using this medicine, and for at least 1 week after your last dose.
Can selpercatinib harm a baby?
Selpercatinib can harm an unborn baby if the mother or father is using this medicine. Keep using birth control for at least 1 week after your last dose. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using selpercatinib.
Can you take Selpercatinib if you have high blood pressure?
You should not use selpercatinib if you have untreated or uncontrolled hypertension ( high blood pressure ). Tell your doctor if you have ever had: liver disease; or. long QT syndrome (in you or a family member). Both men and women using selpercatinib should use effective birth control to prevent pregnancy.
When was Selpercatinib approved?
On May 8, 2020, the Food and Drug Administration granted accelerated approval to selpercatinib (RETEVMO, Eli Lilly and Company) for the following indications: Adult patients with metastatic RET fusion-positive non-small cell lung cancer (NSCLC); Adult and pediatric patients ≥12 years of age with advanced or metastatic RET -mutant medullary thyroid ...
How to report adverse events to the FDA?
Healthcare professionals should report all serious adverse events suspected to be associated with the use of any medicine and device to FDA’s MedWatch Reporting System or by calling 1-800-FDA-1088.
How effective is RET-mutant MTC?
Efficacy for advanced or metastatic RET -mutant MTC was investigated in adults and pediatric patients (≥12 years of age). The trial enrolled patients previously treated with cabozantinib, vandetanib, or both, and patients who had not received these drugs. The ORR for the 55 previously treated patients was 69% (95% CI: 55%, 81%); 76% of responding patients had responses lasting 6 months or longer. Efficacy was also evaluated in 88 patients not previously treated with an approved therapy for MTC. The ORR for these patients was 73% (95% CI: 62%, 82%); 61% of responding patients had responses lasting 6 months or longer.
Can you take Selpercatinib with food?
Selpercatinib is taken orally twice daily with or without food; or with food when co-administered with a proton pump inhibitor. View full prescribing information for RETEVMO. This review used the Assessment Aid, a voluntary submission from the applicant to facilitate the FDA’s assessment.
Is accelerated approval contingent upon verification of clinical benefit?
This application was granted accelerated approval based on overall response rate and response duration. Continued approval may be contingent upon verification of clinical benefit in confirmatory trials.
Why is Selpercatinib prescribed?
Selpercatinib is used to treat a certain type of non-small cell lung cancer (NSCLC) in adults that has spread to other parts of the body in adults. It is also used to treat a certain type of thyroid cancer in adults and children 12 years of age and older that has spread to other parts of the body.
What to do if you are allergic to Selpercatinib?
Before taking selpercatinib, tell your doctor and pharmacist if you are allergic to selpercatinib, any other medications, or any of the ingredients in selpercatinib capsules. Ask your pharmacist for a list of the ingredients. tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, ...
How should this medicine be used?
Selpercatinib comes as a capsule to take by mouth. It is usually taken twice daily (every 12 hours) with or without food. Take selpercatinib at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take selpercatinib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
What special dietary instructions should I follow?
Do not eat grapefruit or drink grapefruit juice while taking this medication.
How long after selpercatinib do you have to use birth control?
If you are male, you and your female partner should use birth control during your treatment with selpercatinib and for 1 week after your final dose. If you or your partner become pregnant while taking selpercatinib, call your doctor immediately. Selpercatinib can cause fetal harm.
How long before taking selpercatinib?
if you are taking an antacid that contains aluminum, magnesium, calcium, or simethicone; or buffered medications such as buffered aspirin, take selpercatinib at least 2 hours before or at least 2 hours after you take one of these medications.
What to do if you vomit after taking Selpercatinib?
If you vomit after taking selpercatinib, do not take another dose. Continue your regular dosing schedule.
Is Selpercatinib bad for your liver?
Selpercatinib may be harmful to your liver. Seek medical attention if you notice yellowing of the skin or whites of your eyes, dark or brown urine, bleeding, or bruising.
Can you get pregnant while taking Selpercatinib?
Women should not become pregnant and men should not get a partner pregnant while taking selpercatinib. Men and women of childbearing age and potential should use effective contraception during therapy and for a minimum of 1 week after the last dose of selpercatinib.
What is Selpercatinib used for?
Selpercatinib is used to treat metastatic (cancer that has already spread) non-small cell lung cancer (NSCLC) in patients whose tumors have RET fusion-positive genes. Your doctor will perform a test to check for the RET gene fusion before you use selpercatinib.
Can you use alcohol with a medicine?
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Is selpercatinib good for cancer?
Medicines used to treat cancer are very strong and can have many side effects. Before receiving selpercatinib, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
Can you change the dose of Selpercatinib?
The following information includes only the average doses of selpercatinib. If your dose is different, do not change it unless your doctor tells you to do so.
