How can I get additional support with Simponi® treatment?
Janssen CarePath provides the additional support you may need to help you get started with SIMPONI ® treatment, once you and your doctor have decided that SIMPONI ® is right for you. A personally assigned Janssen CarePath Care Coordinator will work closely with you and your doctor to provide the support you need.
Are there any risks in taking Simponi®?
There are reports of serious infections caused by bacteria, fungi, or viruses that have spread throughout the body, including tuberculosis (TB) and histoplasmosis. Some of these infections have been fatal. Your doctor will test you for TB before starting SIMPONI® and will monitor you for signs of TB during treatment.
Can I self-inject Simponi?
Once you and your doctor are comfortable with the self-injection process, you will inject SIMPONI ® under the skin. SIMPONI® (golimumab) is a prescription medicine. SIMPONI® can lower your ability to fight infections.
When should I stop taking Simponi ®?
Discontinue SIMPONI ® if new or worsening symptoms of heart failure appear. TNF-blocking agents, of which SIMPONI ® is a member, have been associated with rare cases of new-onset or exacerbation of demyelinating disorders, including multiple sclerosis (MS) and Guillain-Barré syndrome.
What is the cost of Simponi injection?
The cost for Simponi subcutaneous solution (50 mg/0.5 mL) is around $5,877 for a supply of 0.5 milliliters, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
Is Simponi covered by Medicare Part D?
Do Medicare prescription drug plans cover Simponi? No. In general, Medicare prescription drug plans (Part D) do not cover this drug.
How long does it take Simponi to work?
While individual results may vary, SIMPONI® was proven in clinical studies to: Help people with moderately to severely active UC get their symptoms under control in as few as 6 weeks. Begin to improve the appearance of the intestinal lining in as few as 6 weeks.
What is the difference between Simponi and SIMPONI ARIA?
Simponi and Simponi Aria for psoriatic arthritis Simponi is approved for use in adults alone or in combination with methotrexate. Simponi Aria is approved to treat PsA in adults as well. But the medication can also be used in children ages 2 years and older. PsA is a type of autoimmune condition.
Will Medicare pay for biologics?
Biologics—usually large, complex molecules produced in a living system—are some of the most expensive drugs available, and spending for biologics is growing in Medicare Part D because they treat diseases common among Medicare beneficiaries. Biologics are estimated to cost Part D upwards of $12 billion annually.
Does Medicare Part B cover Simponi Aria infusions?
Do Medicare prescription drug plans cover Simponi Aria? No. In general, Medicare prescription drug plans (Part D) do not cover this drug.
Does SIMPONI cause weight gain?
No, neither Simponi nor Simponi Aria are known to cause weight gain. No one who used either medication reported weight gain as a side effect in clinical trials. However, both medications can, rarely, cause heart failure as a side effect.
Do you have to take biologics forever?
You don't need to stop taking biologics for a minor procedure like removal of a skin cancer lesion. But your doctor might recommend stopping your biologic for a few weeks before open surgery like a knee or hip replacement. That's because these drugs can increase your risk for infection.
Which alcohol is good for arthritis?
Red wine has a compound in it called resveratrol, which has well-established anti-inflammatory effects. Some studies show wine consumption is associated with a reduced risk of knee OA, and moderate drinking is also associated with a reduced risk of RA.
Can you drink alcohol on SIMPONI?
Alcohol. There's no known interaction between golimumab and alcohol, so it's fine to have a drink if you're taking this medication.
Why do you have to take methotrexate with SIMPONI?
Studies have found that when methotrexate is taken with some biologic treatments, like SIMPONI®, the 2 medicines together may help to control the symptoms of RA. Biologics may help relieve the joint pain, stiffness, and swelling caused by moderate to severe RA.
Does SIMPONI cause liver damage?
There have been reports of severe hepatic reactions including acute liver failure in patients receiving TNF blockers.
Are chemo drugs covered under Part D?
Part D covers most prescription medications and some chemotherapy treatments and drugs. If you have Original Medicare with a Medicare drug plan, and Part B doesn't cover a cancer drug, your drug plan may cover it.
What is the price of golimumab?
Table 1Cost Comparison Table for Biologic Disease-Modifying Antirheumatic DrugsComparatorsStrengthPrice ($)IV Golimumab (Simponi IV)50 mg826.8600bSC Golimumab (Simponi SC)50 mg1520.2100Adalimumab (Humira)40 mg740.3600Certolizumab pegol (Cimzia)200 mg664.51009 more rows
Does Medicare pay for immunotherapy?
Medicare covers immunotherapy treatment for cancer. Out-of-pocket costs will vary, depending on the Medicare plan a person has and whether or not they have supplemental insurance. If a person has original Medicare, the costs involve a 20% coinsurance after paying the deductible.
Does Medicare Part B pay for chemo drugs?
Some chemo drugs are covered under Medicare Part B, while others fall under Part D. Medicare also covers most of the cost of a second opinion prior to undergoing cancer surgery.
Where can I get Simponi?
SIMPONI ® is available from a wide range of pharmacies. Janssen CarePath can connect you to a pharmacy and coordinate delivery to your patient’s home or your office.
What are the most common adverse reactions to Simponi?
Upper respiratory tract infection and nasopharyngitis were the most common adverse reactions reported in the combined Phase 3 trials through Week 16, occurring in 7% and 6% of patients treated with SIMPONI ® as compared with 6% and 5% of patients in the control group, respectively. The rate of injection-site reactions was 6% with patients treated with SIMPONI ® compared with 2% of patients in the control group.
What is Janssen CarePath?
Janssen CarePath provides the additional support your patients may need to get started with SIMPONI ® treatment you have prescribed. A personally assigned Janssen CarePath Care Coordinator will work closely with you and your patients to provide personalized support.
Can SIMPONI be used for heart failure?
Some cases had a fatal outcome. Exercise caution and monitor patients with heart failure. Discontinue SIMPONI ® if new or worsening symptoms of heart failure appear.
Does Simponi cause lymphoma?
In the controlled portions of clinical trials of all TNF-blocking agents including SIMPONI ®, more cases of lymphoma have been observed among patients receiving TNF-blocking treatment compared with control patients. In the Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA), and Ankylosing Spondylitis (AS) clinical trials, the incidence of lymphoma per 100 patient-years of follow-up was 0.21 (95% CI: 0.03, 0.77) in the combined SIMPONI ® group compared with an incidence of 0 (95% CI: 0, 0.96) in the placebo group. In clinical trials, the incidence of malignancies other than lymphoma was not increased with exposure to SIMPONI ® and was similar to what would be expected in the general population. In controlled and uncontrolled portions of the Phase 2/3 studies in ulcerative colitis (UC) with a mean follow-up of approximately 1 year, there were no cases of lymphoma with SIMPONI ®. Short follow-up periods, such as those of 1 year or less in the studies above, may not adequately reflect the true incidence of malignancies. Cases of acute and chronic leukemia have been reported with TNF-blocker use, including SIMPONI ®. The risks and benefits of TNF-blocker therapy should be considered prior to initiating therapy in patients with a known malignancy or who develop a malignancy.
Can SIMPONI cause serious infections?
SERIOUS INFECTIONS. Patients treated with SIMPONI® (golimumab) are at increased risk for developing serious infections that may lead to hospitalization or death. Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids.
Does Janssen CarePath take Simponi?
We understand how important it is for your patients to take SIMPONI ® medication as you’ve prescribed. Janssen CarePath offers support that may help your patients get started and stay on track with their SIMPONI ® treatment you have prescribed.
What is SIMPONI used for?
SIMPONI® (golimumab) is a prescription medicine. SIMPONI® can lower your ability to fight infections. There are reports of serious infections caused by bacteria, fungi, or viruses that have spread throughout the body, including tuberculosis (TB) and histoplasmosis. Some of these infections have been fatal. Your doctor will test you for TB before starting SIMPONI® and will monitor you for signs of TB during treatment. Tell your doctor if you have been in close contact with people with TB. Tell your doctor if you have been in a region (such as the Ohio and Mississippi River Valleys and the Southwest) where certain fungal infections like histoplasmosis or coccidioidomycosis are common.
How to cancel SIMPONI?
You can ask to cancel your registration by calling 877-CarePath (877-227-3728) Monday-Friday 8:00 am - 8:00 pm ET or by completing the form below and checking opt out in the Safe Returns ® Program Options .
What is the phone number for Janssen Carepath?
If you have any questions, please call a Janssen CarePath Care Coordinator at 877-CarePath (877-227-3728) , Monday−Friday, 8:00 am to 8:00 pm ET. Multilingual phone support is available.
How long does it take for a nurse to return a call?
At all other times, a nurse will return your call in about 15 minutes.
Does Simponi help with low blood count?
Low blood counts have been seen with SIMPONI ®. If this occurs, your body may not make enough blood cells to help fight infections or help stop bleeding. Your doctor will check your blood counts before and during treatment. Tell your doctor if you have signs such as fever, bruising, bleeding easily, or paleness.
Can you get hives from taking Simponi?
Allergic reactions can happen in people who use TNF-blocker medicines, including SIMPONI ®. Tell your doctor if you have any symptoms of an allergic reaction while taking SIMPONI ® such as hives , swollen face, breathing trouble, or chest pain. Some reactions can be serious and life-threatening.
Can simponia cause liver problems?
LIVER PROBLEMS. Serious liver problems can happen in people using TNF blockers, including SIMPONI ®. Contact your doctor immediately if you develop symptoms such as feeling very tired, skin or eyes look yellow, poor appetite or vomiting, or pain on the right side of your stomach.
What is SIMPONI used for?
SIMPONI® (golimumab) is a prescription medicine. SIMPONI® can lower your ability to fight infections. There are reports of serious infections caused by bacteria, fungi, or viruses that have spread throughout the body, including tuberculosis (TB) and histoplasmosis. Some of these infections have been fatal. Your doctor will test you for TB before starting SIMPONI® and will monitor you for signs of TB during treatment. Tell your doctor if you have been in close contact with people with TB. Tell your doctor if you have been in a region (such as the Ohio and Mississippi River Valleys and the Southwest) where certain fungal infections like histoplasmosis or coccidioidomycosis are common.
What are the side effects of Simponi?
Common side effects of SIMPONI® include: upper respiratory tract infection, reaction at site of injection, and viral infections.
When to tell your doctor about simponia?
Tell your doctor if you are pregnant, planning to become pregnant or are breastfeeding or have a baby and were using SIMPONI ® during pregnancy. Tell your baby’s doctor before your baby receives any vaccine because of an increased risk of infection for up to 6 months after birth.
Can you die from taking Simponi?
HEART FAILURE. Heart failure can occur or get worse in people who use TNF blockers, including SIMPONI®. If you develop new or worsening heart failure with SIMPONI ®, you may need treatment in a hospital, and it may result in death. Your doctor will closely monitor you if you have heart failure.
Does Simponi help with low blood count?
Low blood counts have been seen with SIMPONI ®. If this occurs, your body may not make enough blood cells to help fight infections or help stop bleeding. Your doctor will check your blood counts before and during treatment. Tell your doctor if you have signs such as fever, bruising, bleeding easily, or paleness.
Does Simponi cause cancer?
Some people treated with SIMPONI ® have developed certain kinds of skin cancer. If any changes in the appearance of your skin or growths on your skin occur during or after your treatment with SIMPONI ®, tell your doctor.
Can you start Simponi if you have a history of HIV?
You should not start SIMPONI ® if you have any kind of infection. Tell your doctor if you are prone to or have a history of infections or have diabetes, HIV or a weak immune system. You should also tell your doctor if you are currently being treated for an infection or if you have or develop any signs of an infection such as:
What is SIMPONI used for?
SIMPONI® (golimumab) is a prescription medicine. SIMPONI® can lower your ability to fight infections. There are reports of serious infections caused by bacteria, fungi, or viruses that have spread throughout the body, including tuberculosis (TB) and histoplasmosis. Some of these infections have been fatal. Your doctor will test you for TB before starting SIMPONI® and will monitor you for signs of TB during treatment. Tell your doctor if you have been in close contact with people with TB. Tell your doctor if you have been in a region (such as the Ohio and Mississippi River Valleys and the Southwest) where certain fungal infections like histoplasmosis or coccidioidomycosis are common.
Can you die from taking Simponi?
HEART FAILURE. Heart failure can occur or get worse in people who use TNF blockers, including SIMPONI®. If you develop new or worsening heart failure with SIMPONI ®, you may need treatment in a hospital, and it may result in death. Your doctor will closely monitor you if you have heart failure.
Can simponia cause liver problems?
LIVER PROBLEMS. Serious liver problems can happen in people using TNF blockers, including SIMPONI ®. Contact your doctor immediately if you develop symptoms such as feeling very tired, skin or eyes look yellow, poor appetite or vomiting, or pain on the right side of your stomach.
Does Simponi help with low blood count?
Low blood counts have been seen with SIMPONI ®. If this occurs, your body may not make enough blood cells to help fight infections or help stop bleeding. Your doctor will check your blood counts before and during treatment. Tell your doctor if you have signs such as fever, bruising, bleeding easily, or paleness.
What are the most common adverse reactions to Simponi?
Upper respiratory tract infection and nasopharyngitis were the most common adverse reactions reported in the combined Phase 3 trials through Week 16, occurring in 7% and 6% of patients treated with SIMPONI ® as compared with 6% and 5% of patients in the control group, respectively. The rate of injection-site reactions was 6% with patients treated with SIMPONI ® compared with 2% of patients in the control group.
Can you start Simponi with TB?
The risks and benefits of treatment with SIMPONI® should be carefully considered prior to initiating therapy in patients with chronic or recurrent infection. Do not start SIMPONI® in patients with clinically important active infections, including localized infections. Closely monitor patients for the development of signs and symptoms of infection during and after treatment with SIMPONI®, including the possible development of TB in patients who tested negative for latent TB infection prior to initiating therapy, who are on treatment for latent TB, or who were previously treated for TB infection.
Is SIMPONI a TNF blocker?
TNF-blocking agents, of which SIMPONI ® is a member, have been associated with rare cases of new-onset or ex acerbation of demyelinating disorders, including multiple sclerosis (MS) and Guillain-Barré syndrome. Cases of central demyelination, MS, optic neuritis, and peripheral demyelinating polyneuropathy have rarely been reported with SIMPONI ®. Exercise caution in considering the use of SIMPONI ® in patients with these disorders. Consider discontinuation if these disorders develop.
Can SIMPONI be used for heart failure?
Some cases had a fatal outcome. Exercise caution and monitor patients with heart failure. Discontinue SIMPONI ® if new or worsening symptoms of heart failure appear.
Is simponia a serious infection?
Risk of infection may be higher in patients greater than 65 years of age, patients with co-morbid conditions and/or patients taking concomitant immunosuppressant therapy. Other serious infections observed in patients treated with SIMPONI ® included sepsis, pneumonia, cellulitis, abscess and hepatitis B infection.
Does Simponi cause lymphoma?
In the controlled portions of clinical trials of all TNF-blocking agents including SIMPONI ®, more cases of lymphoma have been observed among patients receiving TNF-blocking treatment compared with control patients. In the Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA), and Ankylosing Spondylitis (AS) clinical trials, the incidence of lymphoma per 100 patient-years of follow-up was 0.21 (95% CI: 0.03, 0.77) in the combined SIMPONI ® group compared with an incidence of 0 (95% CI: 0, 0.96) in the placebo group. In clinical trials, the incidence of malignancies other than lymphoma was not increased with exposure to SIMPONI ® and was similar to what would be expected in the general population. In controlled and uncontrolled portions of the Phase 2/3 studies in ulcerative colitis (UC) with a mean follow-up of approximately 1 year, there were no cases of lymphoma with SIMPONI ®. Short follow-up periods, such as those of 1 year or less in the studies above, may not adequately reflect the true incidence of malignancies. Cases of acute and chronic leukemia have been reported with TNF-blocker use, including SIMPONI ®. The risks and benefits of TNF-blocker therapy should be considered prior to initiating therapy in patients with a known malignancy or who develop a malignancy.
Can you take SIMPONI with Lupus?
Treatment with T NF blockers, including SIMPONI ®, may result in the formation of antinuclear antibodies and, rarely, in the development of a lupus-like syndrome. Discontinue treatment if symptoms suggestive of a lupus-like syndrome develop.
What are the most common adverse reactions to Simponi?
Upper respiratory tract infection and nasopharyngitis were the most common adverse reactions reported in the combined Phase 3 trials through Week 16, occurring in 7% and 6% of patients treated with SIMPONI ® as compared with 6% and 5% of patients in the control group, respectively. The rate of injection-site reactions was 6% with patients treated with SIMPONI ® compared with 2% of patients in the control group.
What are the risks of taking Simponi?
Risk of infection may be higher in patients greater than 65 years of age , patients with co-morbid conditions and/or patients taking concomitant immunosuppressant therapy. Other serious infections observed in patients treated with SIMPONI®included sepsis, pneumonia, cellulitis, abscess and hepatitis B infection. MALIGNANCIES.
What is empiric antifungal therapy?
Consider empiric anti-fungal therapy in patients at risk for invasive fungal infections who develop severe systemic illness. Bacterial, viral, and other infections due to opportunistic pathogens, including Legionella and Listeria.
How long after simponia injection can you give a baby?
Administration of live vaccines to infants exposed to SIMPONI® in uterois not recommended for 6 months following the mother’s last SIMPONI®injection during pregnancy due to an increased risk of infection.
Can SIMPONI cause death?
Patients treated with SIMPONI®(golimumab) are at increased risk for developing serious infections that may lead to hospitalization or death. Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids.
Can you die from simponi?
Patients treated with SIMPONI® (golimumab) are at increased risk for developing serious infections that may lead to hospitalization or death. Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. Discontinue SIMPONI® if a patient develops a serious infection.
Can you start Simponi with TB?
The risks and benefits of treatment with SIMPONI® should be carefully considered prior to initiating therapy in patients with chronic or recurrent infection. Do not start SIMPONI® in patients with clinically important active infections, including localized infections. Closely monitor patients for the development of signs and symptoms of infection during and after treatment with SIMPONI®, including the possible development of TB in patients who tested negative for latent TB infection prior to initiating therapy, who are on treatment for latent TB, or who were previously treated for TB infection.
What is SIMPONI used for?
SIMPONI® (golimumab) is a prescription medicine. SIMPONI® can lower your ability to fight infections. There are reports of serious infections caused by bacteria, fungi, or viruses that have spread throughout the body, including tuberculosis (TB) and histoplasmosis. Some of these infections have been fatal. Your doctor will test you for TB before starting SIMPONI® and will monitor you for signs of TB during treatment. Tell your doctor if you have been in close contact with people with TB. Tell your doctor if you have been in a region (such as the Ohio and Mississippi River Valleys and the Southwest) where certain fungal infections like histoplasmosis or coccidioidomycosis are common.
Can you die from taking Simponi?
HEART FAILURE. Heart failure can occur or get worse in people who use TNF blockers, including SIMPONI®. If you develop new or worsening heart failure with SIMPONI ®, you may need treatment in a hospital, and it may result in death. Your doctor will closely monitor you if you have heart failure.
Can simponia cause liver problems?
LIVER PROBLEMS. Serious liver problems can happen in people using TNF blockers, including SIMPONI ®. Contact your doctor immediately if you develop symptoms such as feeling very tired, skin or eyes look yellow, poor appetite or vomiting, or pain on the right side of your stomach.
Does Simponi help with low blood count?
Low blood counts have been seen with SIMPONI ®. If this occurs, your body may not make enough blood cells to help fight infections or help stop bleeding. Your doctor will check your blood counts before and during treatment. Tell your doctor if you have signs such as fever, bruising, bleeding easily, or paleness.
How often is SIMPONI given?
MTX is used as directed. For RA, PsA, and AS: SIMPONI ® 50 mg is given as an injection under the skin (subcutaneous injection) once a month. For UC: SIMPONI ® begins with 3 starter injections under the skin (subcutaneous injection): Two 100-mg injections on the first day of treatment, followed by one 100-mg injection 2 weeks later.
What are the side effects of Simponi?
Common side effects of SIMPONI® include: upper respiratory tract infection, reaction at site of injection, and viral infections.
What is SIMPONI 50 mg?
MTX is used as directed. For RA, PsA, and AS: SIMPONI ® 50 mg is given as an injection under the skin (subcutaneous injection) once a month.
What are the symptoms of simponia?
Tell your doctor if you know or think you may be a carrier of hepatitis B virus or if you experience signs of hepatitis B infection, such as: feel very tired. dark urine. skin or eyes look yellow.
How often should I inject Simponi?
After these 3 starter injections, SIMPONI ® requires one 100-mg injection every 4 weeks. Once you and your doctor are comfortable with the self-injection process, you will inject SIMPONI ® under the skin. Important Safety Information For SIMPONI ®.
When to tell your doctor about simponia?
Tell your doctor if you are pregnant, planning to become pregnant or are breastfeeding or have a baby and were using SIMPONI ® during pregnancy. Tell your baby’s doctor before your baby receives any vaccine because of an increased risk of infection for up to 6 months after birth.
Does Simponi cause cancer?
Some people treated with SIMPONI ® have developed certain kinds of skin cancer. If any changes in the appearance of your skin or growths on your skin occur during or after your treatment with SIMPONI ®, tell your doctor.
What are the most common adverse reactions to Simponi?
Upper respiratory tract infection and nasopharyngitis were the most common adverse reactions reported in the combined Phase 3 trials through Week 16, occurring in 7% and 6% of patients treated with SIMPONI ® as compared with 6% and 5% of patients in the control group, respectively. The rate of injection-site reactions was 6% with patients treated with SIMPONI ® compared with 2% of patients in the control group.
Can you start Simponi with TB?
The risks and benefits of treatment with SIMPONI® should be carefully considered prior to initiating therapy in patients with chronic or recurrent infection. Do not start SIMPONI® in patients with clinically important active infections, including localized infections. Closely monitor patients for the development of signs and symptoms of infection during and after treatment with SIMPONI®, including the possible development of TB in patients who tested negative for latent TB infection prior to initiating therapy, who are on treatment for latent TB, or who were previously treated for TB infection.
Is SIMPONI a TNF blocker?
TNF-blocking agents, of which SIMPONI ® is a member, have been associated with rare cases of new-onset or ex acerbation of demyelinating disorders, including multiple sclerosis (MS) and Guillain-Barré syndrome. Cases of central demyelination, MS, optic neuritis, and peripheral demyelinating polyneuropathy have rarely been reported with SIMPONI ®. Exercise caution in considering the use of SIMPONI ® in patients with these disorders. Consider discontinuation if these disorders develop.
Can SIMPONI be used for heart failure?
Some cases had a fatal outcome. Exercise caution and monitor patients with heart failure. Discontinue SIMPONI ® if new or worsening symptoms of heart failure appear.
Does Simponi cause lymphoma?
In the controlled portions of clinical trials of all TNF-blocking agents including SIMPONI ®, more cases of lymphoma have been observed among patients receiving TNF-blocking treatment compared with control patients. In the Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA), and Ankylosing Spondylitis (AS) clinical trials, the incidence of lymphoma per 100 patient-years of follow-up was 0.21 (95% CI: 0.03, 0.77) in the combined SIMPONI ® group compared with an incidence of 0 (95% CI: 0, 0.96) in the placebo group. In clinical trials, the incidence of malignancies other than lymphoma was not increased with exposure to SIMPONI ® and was similar to what would be expected in the general population. In controlled and uncontrolled portions of the Phase 2/3 studies in ulcerative colitis (UC) with a mean follow-up of approximately 1 year, there were no cases of lymphoma with SIMPONI ®. Short follow-up periods, such as those of 1 year or less in the studies above, may not adequately reflect the true incidence of malignancies. Cases of acute and chronic leukemia have been reported with TNF-blocker use, including SIMPONI ®. The risks and benefits of TNF-blocker therapy should be considered prior to initiating therapy in patients with a known malignancy or who develop a malignancy.
Is simponia a serious infection?
Risk of infection may be higher in patients greater than 65 years of age, patients with co-morbid conditions and/or patients taking concomitant immunosuppressant therapy. Other serious infections observed in patients treated with SIMPONI ® included sepsis, pneumonia, cellulitis, abscess and hepatitis B infection.
Can you take SIMPONI with Lupus?
Treatment with T NF blockers, including SIMPONI ®, may result in the formation of antinuclear antibodies and, rarely, in the development of a lupus-like syndrome. Discontinue treatment if symptoms suggestive of a lupus-like syndrome develop.
