
Patient Assistance Programs for Sirolimus Patient assistance programs (PAPs) are usually sponsored by pharmaceutical companies and provide free or discounted medicines to low income or uninsured and under-insured people who meet specific guidelines. Eligibility requirements vary for each program.
Full Answer
Are there any discounts or promotions available for sirolimus?
Sirolimus offers may be in the form of a printable coupon, rebate, savings card, trial offer, or free samples. Some offers may be printed right from a website, others require registration, completing a questionnaire, or obtaining a sample from the doctor's office. There are currently no Manufacturer Promotions that we know about for this drug.
How much does Rapamune (sirolimus) cost?
Are you looking for a place to get your Rapamune (Sirolimus) medication at an affordable price? Prescription Hope offers the top medications prescribed on a national level all for the set price of $50 per month for each medication! Who is Prescription Hope?
What is sirolimus?
Sirolimus is a member of the mTOR inhibitors drug class and is commonly used for Lymphangioleiomyomatosis and Organ Transplant - Rejection Prophylaxis. Brand names for sirolimus include Rapamune. Sirolimus Prices. This sirolimus price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
Is sirolimus a substrate for cytochrome P450 3A4?
Sirolimus is known to be a substrate for both cytochrome P-450 3A4 (CYP3A4) and p-glycoprotein (P-gp). Inducers of CYP3A4 and P-gp may decrease sirolimus concentrations whereas inhibitors of CYP3A4 and P-... Did you find an answer to your question? Yes No Based on animal studies... Did you find an answer to your question? Yes No

What is Pfizer Assistance Program?
Pfizer RxPathways® patients in need get access to their Pfizer medicines. Today, Pfizer RxPathways® connects eligible U.S. patients to a range of Pfizer assistance programs that provide insurance support, co-pay help, and medicines for free or at a savings.
What drug company makes sirolimus?
Pfizer's RAPAMUNE® (sirolimus) Becomes First FDA-Approved Treatment for Lymphangioleiomyomatosis (LAM), A Rare Progressive Lung Disease. Pfizer Inc.
How much does Rapamune cost?
The cost for Rapamune oral tablet 0.5 mg is around $1,750 for a supply of 100 tablets, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
What is the generic brand for Rapamune?
The U.S. pharmaceutical world named the generic medication, sirolimus.
How long can you take sirolimus for?
Take sirolimus exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Swallow the tablets whole; do not split, chew, or crush them. Your doctor will probably adjust your dose of sirolimus during your treatment, usually not more than once every 7 to 14 days.
Is there a generic for sirolimus?
January 30, 2019 - VistaPharm launched a generic version of Pfizer's Rapamune (sirolimus) oral solution.
How expensive is sirolimus?
The retail price Sirolimus is $503.72 for 30, 1MG Tablet, but it can be reduced to $70.91 for 30, 1mg Tablet.
Does sirolimus cause hair loss?
mTOR Inhibitors: Everolimus, Temsirolimus, Sirolimus mTOR inhibitors are drugs with many wide-ranging indications that generally have limited impact on hair. 31, 85 These agents are considered as an uncommon cause of hair loss.
Is sirolimus the same as Rapamune?
Rapamycin (Sirolimus, Rapamune), a potent immunosuppressive agent, has been demonstrated to have remarkable activity in inhibiting allograft rejection in animal models of transplantation. It is currently in phase II clinical trials.
Does sirolimus cause weight gain?
Check with your doctor right away if you or your child is having more than one of these symptoms: bloody urine, a decreased frequency or amount of urine, increased thirst, loss of appetite, lower back or side pain, nausea, swelling of the face, fingers, or lower legs, trouble breathing, unusual tiredness or weakness, ...
Can you stop taking sirolimus?
Do not change your dose or stop taking this medicine without checking first with your doctor. You may have to take this medicine for the rest of your life to prevent your body from rejecting the kidney transplant. Sirolimus is usually used along with a corticosteroid (cortisone-like medicine) and cyclosporine.
Does sirolimus cause high blood pressure?
Bruising, bleeding. Acne. High blood pressure, which may cause headaches, dizziness, blurred vision. Difficulty sleeping.
Where is sirolimus manufactured?
Sirolimus | compare suppliers & send inquiries for freeDKSH Type: Distributor Produced in: SwitzerlandDistributorBiocon Type: Producer Produced in: IndiaProducer−Otto Brandes GmbH MOQ: 25 g Type: Distributor Produced in: GermanyMOQ: 25 g Distributor−16 more rows
Who produces rapamycin?
Rapamycin is currently manufactured and marketed by Wyeth as Rapamune for the prevention of organ graft rejection in kidney transplant patients and is also used as a coating for vascular stents to prevent restenosis of coronary arteries following angioplasty (13).
Who makes rapamycin?
Pfizer, which bought Wyeth in 2009, markets it under the name Rapamune (sirolimus). As rapamycin was wending its way through clinical trials for transplant patients in the mid-1990s, scientists at Wyeth turned their attention to using the compound to fight cancer.
Does sirolimus cause liver damage?
The liver injury associated with sirolimus therapy is usually mild and transient, resolving on its own or with dose modification or discontinuation. Sirolimus has not been linked to cases of acute liver failure or vanishing bile duct syndrome.
What is Sirolimus used for?
Sirolimus is a member of the mTOR inhibitors drug class and is commonly used for Lymphangioleiomyomatosis, and Organ Transplant - Rejection Prophylaxis.
How much does sirolimus cost?
Sirolimus Prices. The cost for sirolimus oral tablet 1 mg is around $240 for a supply of 30, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
Does Sirolimus have a coupon?
Sirolimus Coupons and Rebates. Sirolimus offers may be in the form of a printable coupon, rebate, savings card, trial offer, or free samples. Some offers may be printed right from a website, others require registration, completing a questionnaire, or obtaining a sample from the doctor's office.
Who is Prescription Hope?
Prescription Hope is a nationally recognized prescription medication access program, headquartered in Columbus, Ohio. Prescription Hope offers access to over 1,500 brand-name medications through patient assistance programs. All you pay is a set service fee of $50 for each medication per month. This includes 100% of the medication cost, no matter the retail price.
Is Prescription Hope A Rapamune Coupon Card, Generic, Or Insurance Product?
Prescription Hope is not a Rapamune coupon card or insurance policy. Our program is also not a Rapamune Generic. Prescription Hope is a national advocacy program that works with any coverage you may already have. Although Prescription Hope is not a Rapamune coupon, individuals looking for a Rapamune coupon can find more savings through Prescription Hope!
Can Prescription Hope Get My Rapamune If I Have Health Insurance Coverage?
Because Prescription Hope is not a health insurance plan, our program works alongside any coverage you may currently have to obtain your Rapamune medication at an affordable price. Our national advocacy program does not have medication tiers, copays, or deductibles.
Can Prescription Hope Help Me Obtain My Other Medications?
Prescription Hope works directly with over 180 U.S. based pharmaceutical manufacturers patient assistance programs to obtain over 1,500 FDA-approved prescription medications. Visit our website to see our full list of medications and fill out an application.
How much does prescription hope cost?
Prescription Hope is a national advocacy program that can obtain over 1,500 FDA-approved prescription medications directly from the pharmaceutical companies and their pharmacy for the set price of $50.00 per month per medication .
What is rapamune used for?
Rapamune is used to decrease the immune system’s response to a transplanted organ, usually after a kidney transplant. This medication can also be used to treat a rare lung disease called lymphangioleiomyomatosis. Important Safety Information & Side Effects:
How long does it take for a prescription to arrive?
Once your application is approved, the first shipment of prescription medication typically arrives within four to six weeks.
What is Pfizer Patient Assistance Program?
The Pfizer Patient Assistance Program provides eligible patients with select Pfizer medicines for free. To qualify: Patients must not have any prescription drug coverage, or not enough coverage to pay for their Pfizer medicines. Patients must meet program income guidelines, which vary by product and household size.
What to do if a patient has no income and does not file taxes?
NOTE: If patient has no income and does not file taxes, a letter from the physician stating the patient has no income OR a notarized letter from a family member is required.
Do patients have to meet income guidelines?
Patients must meet program income guidelines, which vary by product and household size.
How often is rapamune given?
Rapamune is to be administered orally once daily, consistently with or without food [ see
What is rapamune used for?
Rapamune (sirolimus) is indicated for the prophylaxis of organ rejection in...
Is Rapamune absorbed through the skin?
16 HOW SUPPLIED/STORAGE AND HANDLING. Since Rapamune is not absorbed through the skin, there are no special precautions. However, if direct contact of the oral solution occurs with the skin or eyes, wash skin thoroughly with... Read more.
Is rapamune contraindicated?
Rapamune is contraindicated in patients with a hypersensitivity to Rapamune [ see Warnings and Precautions (5.4) ].
Does sirolimus inhibit T lymphocytes?
Sirolimus inhibits T-lymphocyte activation and proliferation that occurs in response to antigenic and cytokine (...
Can you overdose on Rapamune?
Reports of overdose with Rapamune have been received; however, experience has been limited. In general, the adverse effects of overdose are consistent with those listed in the adverse reactions section [...
Is sirolimus a substrate for p-glycoprotein?
Sirolimus is known to be a substrate for both cytochrome P-450 3A4 (CYP3A4) and p-glycoprotein (P- gp). Inducers of CYP3A4 and P-gp may decrease sirolimus concentrations whereas inhibitors of CYP3A4 and P-... Read more.

Important Note
- The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your …
How to Use
- Take this medication by mouth usually once daily, exactly as prescribed by your doctor. The dosage is based on your medical condition and response to therapy. This medication works best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals (e.g., every 24 hours) and take this drug consistently either with or witho…
Precautions
- Tell your doctor your medical history, especially of: liver or kidney problems, high cholesterol or triglyceride levels, any allergies. This drug may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcohol intake because it can intensify the dizziness effects of this medication. This medication may make you more suscepti…
Drug Interactions
- Tell your doctor of all prescription and nonprescription medication you may use, especially: drugs for high cholesterol or triglycerides (e.g., lovastatin, atorvastatin, gemfibrozil), calcium-channel blockers (e.g., diltiazem, verapamil, nicardipine), rifamycin antibiotics (e.g., rifampin, rifabutin), macrolide antibiotics (e.g., clarithromycin, erythromycin), aminoglycoside antibiotics (e.g., genta…
Overdose
- If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include: unusually fast heartbeat.
Notes
- Do not share this medication with others. Keep all scheduled medical appointments. Laboratory and medical tests will be performed to monitor your condition and response to therapy.
Missed Dose
- If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Storage
- Store at room temperature between 68 and 77 degrees F (20 and 25 degrees C) away from light and moisture.
Medical Alert
- Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).