Patient Assistance & Copay Programs for Sorafenib Patient assistance programs (PAPs) are usually sponsored by pharmaceutical companies and provide free or discounted medicines and copay programs to low income or uninsured and under-insured people who meet specific guidelines. Eligibility requirements vary for each program.
Full Answer
What is the cost of Nexavar?
The cost for Nexavar oral tablet 200 mg is around $24,033 for a supply of 120 tablets, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans. This Nexavar price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
When should I stop taking Nexavar?
risk of wound healing problems. Tell your healthcare provider if you plan to have any surgery before starting or during treatment with NEXAVAR. You should stop taking NEXAVAR at least 10 days before planned surgery. Your healthcare provider should tell you when you may start taking NEXAVAR again after surgery.
Is Nexavar a chemotherapy?
What Is Nexavar? Nexavar (sorafenib) is a cancer (chemotherapeutic) medication used to treat a type of kidney cancer called advanced renal cell carcinoma. Nexavar is also used to treat liver cancer.
Is sorafenib a generic drug?
Natco Pharma has announced the launch of the first generic version of Nexavar (Sorafenib) tablets in the US market on Wednesday. The product will be launched by Hyderabad-based Natco Pharma's commercial partner, Viatris, a global pharmaceutical company.
How long can you live with sorafenib?
Median overall survival was 26.1 months with overall 6- and 12-month survival rates of 92.1 and 85%, respectively. Median time to radiological progression was 8 months. The progression-free rate was 64.3%. Fatigue, skin disorders and diarrhea were the most frequent grade 3-4 side effects.
How can I reduce the side effects of sorafenib?
Do not split, chew, or crush them. Your doctor may decrease your dose of sorafenib during your treatment, or may tell you to temporarily or permanently stop taking sorafenib for a period of time if you experience side effects. Be sure to tell your doctor how you are feeling during your treatment with sorafenib.
Does sorafenib cause hair loss?
These are less common side effects for patients receiving Nexavar, when compared with those receiving placebo: High blood pressure (particularly in first 6 weeks of treatment) Hair loss (thinning or patchy hair loss) Nausea.
How effective is sorafenib?
Sorafenib was associated with a nonsignificant reduction in mortality at 3 months (44% versus 51%; adjusted risk ratio, 0.88 [95% CI, 0.72-1.07]), but no reduction thereafter.
What happens when you stop taking sorafenib?
Our results showed that the side effects of sorafenib, such as HFSR, diarrhea and hypertension, resolved after the discontinuation of sorafenib. Weight loss and alopecia also improved gradually.
Is sorafenib covered by Medicare?
Do Medicare prescription drug plans cover sorafenib? No. In general, Medicare prescription drug plans (Part D) do not cover this drug.
When did sorafenib go off patent?
Bayer owns Indian Patent 215758 that claims sorafenib tosylate and expires on January 12, 2020.
What is sorafenib target?
Cellular targets of sorafenib. Sorafenib blocks receptor tyrosine kinase signaling (VEGFR, PDGFR, c-Kit and RET) and inhibits downstream Raf serine/threonine kinase activity to prevent tumor growth by anti-angiogenic, antiproliferative and/or pro-apoptotic effects10 (from Bayer website).
What happens when you stop taking sorafenib?
Our results showed that the side effects of sorafenib, such as HFSR, diarrhea and hypertension, resolved after the discontinuation of sorafenib. Weight loss and alopecia also improved gradually.
How effective is Nexavar?
The patients administered with Nexavar showed a 41% reduction in the risk of progression or death when compared to placebo-treated patients. The median PFS was 10.8 months in patients treated with Nexavar, compared to 5.8 months in patients receiving placebo.
Can Nexavar shrink tumors?
Sorafenib (Nexavar; Bayer) shrinks desmoid tumors in one third of patients, according to a recent clinical trial thatcould lead to the first drug approval for the disease (N Engl J Med 2018;379:2417–28).
Does Nexavar cause hair loss?
These are less common side effects for patients receiving Nexavar, when compared with those receiving placebo: High blood pressure (particularly in first 6 weeks of treatment) Hair loss (thinning or patchy hair loss) Nausea.
What is the phone number for BUSPAF?
Provides free medicine for patients who are uninsured or underinsured and meet certain eligibility criteria. Call 1-866-2BUSPAF (228-7723) to speak with a reimbursement counselor (Monday‐Friday, 8:30 am-6 pm ET) Learn More.
Where to report side effects of prescription drugs?
You are encouraged to report negative side effects or quality complaints of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
How long after Nexavar can you breastfeed?
Do not breastfeed during treatment with NEXAVAR and for 2 weeks after receiving the last dose of NEXAVAR. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
What is the name of the cancer that can no longer be treated with radioactive iodine?
a type of thyroid cancer called differentiated thyroid carcinoma (DTC) that can no longer be treated with radioactive iodine and is progressing
Can Nexavar harm a baby?
NEXAVAR may harm your unborn baby. Tell your healthcare provider right away if you become pregnant during treatment with NEXAVAR. For females who are able to become pregnant: Your healthcare provider should do a pregnancy test before you start treatment with NEXAVAR.
Does Nexavar help with wound healing?
risk of wound healing problems. Wounds may not heal properly during NEXAVAR treatment. Tell your healthcare provider if you plan to have any surgery before starting or during treatment with NEXAVAR.
Can you take Nexavar if you are allergic to sorafenib?
Do not take NEXAVAR if you: are allergic to sorafenib or any of the other ingredients in NEXAVAR. have squamous cell lung cancer and receive carboplatin and paclitaxel.
What to tell your healthcare provider before taking Nexavar?
Before taking NEXAVAR, tell your healthcare provider about all of your medical conditions, including if you: have heart problems including a condition called “congenital long QT syndrome”. have chest pain. have abnormal magnesium, potassium, or calcium blood levels. have bleeding problems. have high blood pressure.
Where to report a negative side effect of Nexavar?
You are encouraged to report negative side effects or quality complaints of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088. For important risk and use information about NEXAVAR, please see the full Prescribing Information.
How long after nexavar is used?
Use effective birth control (contraception) during your treatment with NEXAVAR and for 6 months after the last dose of NEXAVAR. For males with female partners who are able to become pregnant: Use effective birth control (contraception) during your treatment with NEXAVAR and for 3 months after the last dose of NEXAVAR.
What is the name of the cancer that can no longer be treated with radioactive iodine?
a type of thyroid cancer called differentiated thyroid carcinoma (DTC) that can no longer be treated with radioactive iodine and is progressing
Can Nexavar cause bleeding?
increased risk of bleeding. Bleeding is a common side effect of NEXAVAR that can be serious and can lead to death. Tell your healthcare provider right away if you have any signs of bleeding during treatment with NEXAVAR:
Can Nexavar harm a baby?
are pregnant or plan to become pregnant. NEXAVAR may harm your unborn baby. Tell your healthcare provider right away if you become pregnant during treatment with NEXAVAR. For females who are able to become pregnant: Your healthcare provider should do a pregnancy test before you start treatment with NEXAVAR.
Does Nexavar help with wound healing?
risk of wound healing problems. Wounds may not heal properly during NEXAVAR treatment. Tell your healthcare provider if you plan to have any surgery before starting or during treatment with NEXAVAR.
Can Prescription Hope Help Me Obtain My Other Medications?
Prescription Hope works directly with over 180 U.S. based pharmaceutical manufacturers patient assistance programs to obtain over 1,500 FDA-approved prescription medications. Visit our website to see our full list of medications and fill out an application.
Is Prescription Hope A Nexavar Coupon Card, Generic, Or Insurance Product?
Prescription Hope is not a Nexavar coupon card or insurance policy. Our program is also not a Nexavar Generic. Prescription Hope is a national advocacy program that works with any coverage you may already have. Although Prescription Hope is not a Nexavar coupon, individuals looking for a Nexavar coupon can find more savings through Prescription Hope!
What is the incidence of ischemia in a nexavar group?
Cardiovascular Events: In the SHARP (HCC) study, the incidence of cardiac ischemia/infarction was 2.7% in NEXAVAR-treated patients compared with 1.3% for placebo-treated group. In the TARGET (RCC) study, the incidence of cardiac ischemia/infarction was higher in the NEXAVAR-treated group (2.9%) compared with the placebo-treated group (0.4%). In the DECISION (DTC) study, the incidence of cardiac ischemia/infarction was 1.9% in the NEXAVAR-treated group compared with 0% in the placebo-treated group. Patients with unstable coronary artery disease or recent myocardial infarction were excluded from this study. Consider temporary or permanent discontinuation of NEXAVAR in patients who develop cardiovascular events.
What does Access Services by Bayer refer patients to?
If ineligible, an Access Services by Bayer counselor will refer patients to independent charitable organizations to assist with out-of-pocket costs
What are the most common laboratory abnormalities observed in the Nexavar study?
In the DTC study, the most common laboratory abnormalities observed in the NEXAVAR arm versus the placebo arm, respectively, were elevated ALT (59% vs. 24%), elevated AST (54% vs. 15%), and hypocalcemia (36% vs. 11%). The relative increase for the following laboratory abnormalities observed in NEXAVAR-treated DTC patients as compared to placebo-treated patients is similar to that observed in the RCC and HCC studies: lipase, amylase, hypokalemia, hypophosphatemia, neutropenia, lymphopenia, anemia, and thrombocytopenia.
What is the treatment for hepatocellular carcinoma?
STIVARGA is indicated for the treatment of patients with hepatocellular carcinoma (HCC) who have been previously treated with sorafenib.
What is Nexavar used for?
NEXAVAR is indicated for the treatment of patients with advanced renal cell carcinoma (RCC). NEXAVAR is indicated for the treatment of patients with locally recurrent or metastatic, progressive, differentiated thyroid carcinoma (DTC) that is refractory to radioactive iodine treatment.
How long after Nexavar can you breastfeed?
Lactation: Because of the potential for serious adverse reactions in a breastfed child from NEXAVAR, advise lactating women not to breastfeed during treatment with NEXAVAR and for 2 weeks after the last dose.
How long to wait to take Nexavar after surgery?
Withhold NEXAVAR for at least 10 days prior to elective surgery. Do not administer for at least 2 weeks following major surgery and until adequate wound healing.
What is the incidence of ischemia in a nexavar group?
Cardiovascular Events: In the SHARP (HCC) study, the incidence of cardiac ischemia/infarction was 2.7% in NEXAVAR-treated patients compared with 1.3% for placebo-treated group. In the TARGET (RCC) study, the incidence of cardiac ischemia/infarction was higher in the NEXAVAR-treated group (2.9%) compared with the placebo-treated group (0.4%). In the DECISION (DTC) study, the incidence of cardiac ischemia/infarction was 1.9% in the NEXAVAR-treated group compared with 0% in the placebo-treated group. Patients with unstable coronary artery disease or recent myocardial infarction were excluded from this study. Consider temporary or permanent discontinuation of NEXAVAR in patients who develop cardiovascular events.
How to report a drug to the FDA?
You are encouraged to report negative side effects or quality complaints of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. For Bayer products you can report these directly to Bayer by clicking here.
What are the most common laboratory abnormalities observed in the Nexavar study?
In the DTC study, the most common laboratory abnormalities observed in the NEXAVAR arm versus the placebo arm, respectively, were elevated ALT (59% vs. 24%), elevated AST (54% vs. 15%), and hypocalcemia (36% vs. 11%). The relative increase for the following laboratory abnormalities observed in NEXAVAR-treated DTC patients as compared to placebo-treated patients is similar to that observed in the RCC and HCC studies: lipase, amylase, hypokalemia, hypophosphatemia, neutropenia, lymphopenia, anemia, and thrombocytopenia.
What is the treatment for hepatocellular carcinoma?
STIVARGA is indicated for the treatment of patients with hepatocellular carcinoma (HCC) who have been previously treated with sorafenib.
How long after Nexavar can you breastfeed?
Lactation: Because of the potential for serious adverse reactions in a breastfed child from NEXAVAR, advise lactating women not to breastfeed during treatment with NEXAVAR and for 2 weeks after the last dose.
What is Nexavar used for?
NEXAVAR is indicated for the treatment of patients with advanced renal cell carcinoma (RCC). NEXAVAR is indicated for the treatment of patients with locally recurrent or metastatic, progressive, differentiated thyroid carcinoma (DTC) that is refractory to radioactive iodine treatment.
How long to wait to take Nexavar after surgery?
Withhold NEXAVAR for at least 10 days prior to elective surgery. Do not administer for at least 2 weeks following major surgery and until adequate wound healing.
How much does a free drug card save?
The free Drugs.com Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions.
How much does Nexavar cost?
The cost for Nexavar oral tablet 200 mg is around $21,683 for a supply of 120 tablets, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
What is Nexavar used for?
Nexavar (sorafenib) is a member of the multikinase inhibitors drug class and is commonly used for Hepatic Tumor, Hepatocellular Carcinoma, Renal Cell Carcinoma, and others.
