How long do you take SPRYCEL for CML?
Sprycel is used as a long term treatment and in clinical trials has been taken for 5 years. You usually keep on taking it as long as: your tests show it is working well.
Is SPRYCEL considered chemotherapy?
No, Sprycel is used to treat certain types of leukemia, but it isn't a chemotherapy drug. Chemotherapy drugs work by killing cells that grow and multiply rapidly, including cancer cells. (Cells that multiply are making more cells.)
Is there a generic SPRYCEL?
SPRYCEL is the trade name for the generic chemotherapy drug Dasatinib. In some cases, health care professionals may use the trade name SPRYCEL when referring to the generic drug name Dasatinib.
When is the best time of day to take SPRYCEL?
How should SPRYCEL be taken?Do take SPRYCEL one (1) time a day.Do take SPRYCEL with or without food, either in the morning or in the evening, at the same time each day*Do swallow SPRYCEL tablets whole with water.If your child cannot swallow tablets whole, talk to your healthcare provider.
What are the long term effects of SPRYCEL?
However, some side effects of Sprycel might last longer. Examples of long-term side effects include heart damage from having an abnormal heart rhythm. Or you may have permanent lung damage after experiencing pulmonary hypertension (high blood pressure that occurs in your lungs).
What is the life expectancy of someone with CML?
Today, the ten year survival rate for the most common form of CML is approximately 85% and patients can expect to live life-spans nearly as long as normal healthy adults.
Does SPRYCEL make you tired?
Fatigue. Fatigue, which is a lack of energy, is also a common side effect of Sprycel. In clinical studies of adults who took only Sprycel for Ph+ CML in the chronic phase and had previous treatment with imatinib, up to 19% of them had fatigue.
When does dasatinib go off patent?
FDA authorized dasatinib in June 2006, and the US patent is expected to expire in October 2025, providing more than 19 years of market exclusivity to recoup the investment.
Does SPRYCEL cause stomach problems?
Side effects of SPRYCEL that are considered most common in children receiving SPRYCEL with chemotherapy include: swelling, pain and redness of the lining of your mouth, throat, stomach and bowel (mucositis), low white blood cell counts with fever, fever, diarrhea, nausea, vomiting, muscle pain, stomach-area (abdominal) ...
What should be avoided in SPRYCEL?
The blood levels of this medication can be affected by certain foods and medications, so they should be avoided. These include: grapefruit, grapefruit juice, verapamil, ketoconazole, rifampin, phenytoin, St. John's wort, and modafanil.
What happens if you stop taking SPRYCEL?
If you stop taking TKIs, you might develop withdrawal symptoms, such as skin rash or pain in your bones and muscles. In most cases, these symptoms can be managed with over-the-counter pain relievers. In some cases, your doctor might prescribe corticosteroids to provide relief.
Can you drink alcohol while taking dasatinib?
Tell your doctor if you drink alcohol. Alcohol is not expected to interact with TE-DASATINIB. If you drink alcohol, talk to your doctor about the possible effects of taking alcohol with this medicine.
Does SPRYCEL make you lose hair?
Hair loss is a possible side effect of Sprycel. Individual clinical studies didn't report how often hair loss occurred. However, combined data across studies of chronic myeloid leukemia (CML) and ALL estimated hair loss to affect 1% to 10% of people who took only Sprycel.
What happens if you stop taking SPRYCEL?
If you stop taking TKIs, you might develop withdrawal symptoms, such as skin rash or pain in your bones and muscles. In most cases, these symptoms can be managed with over-the-counter pain relievers. In some cases, your doctor might prescribe corticosteroids to provide relief.
What class of drug is dasatinib?
Dasatinib is in a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply.
Is CML leukemia is fatal?
In the past, CML was considered a deadly disease. Today, modern treatment options have significantly improved the outlook of people with CML. Before the advent of targeted drug therapy, the five-year survival rate for people with CML was only 22%. Today, the overall five-year survival rate is 90%.
How long is a prescription for Sprycel valid?
Patients must be new to SPRYCEL and have not previously filled a prescription for SPRYCEL. Patients must have a valid 30-day prescription for SPRYCEL. The Free Trial may not be redeemed on prescriptions written for longer than 30 days. Patients or their guardian must be 18 years of age or older.
What are the side effects of spraycel?
headache. skin rash. shortness of breath. tiredness. na usea. muscle pain. The most common side effects of SPRYCEL in children receiving SPRYCEL with chemotherapy include: swelling, pain, and redness of the lining of your mouth, throat, stomach, and bowel (mucositis) low white blood cell counts with fever.
How long after taking Sprycel can you breastfeed?
Breastfeeding or plan to breastfeed. It is not known if SPRYCEL passes into your breast milk. You should not breastfeed during treatment and for 2 weeks after your last dose of SPRYCEL.
Can you get low blood count with spraccel?
Low blood cell counts: Low blood cell counts are common with SPRYCEL and can be severe, including low red blood cell counts (anemia), low white blood cell counts (neutropenia), and low platelet counts (thrombocytopenia). Your healthcare provider will do blood tests to check your blood cell counts regularly during your treatment with SPRYCEL. Call your healthcare provider right away if you have any of these symptoms during treatment with SPRYCEL:
Does Sprycel cause low red blood cells?
SPRYCEL may cause serious side effects, including those listed below. Call your healthcare provider right away if you have any symptoms of the side effects below, or any other concerns about these side effects: Low blood cell counts: Low blood cell counts are common with SPRYCEL and can be severe, including low red blood cell counts (anemia), ...
Can you change your dose of Sprycel?
Take SPRYCEL exactly as your healthcare provider tells you to take it. Your healthcare provider may change your dose of SPRYCEL or temporarily stop treatment with SPRYCEL. Do not change your dose or stop taking SPRYCEL without first talking to your healthcare provider.
Does Bristol Myers Squibb reimburse?
The accurate completion of reimbursement- or coverage-related documentation is the responsibility of the healthcare provider and patient. Bristol Myers Squibb and its agents make no guarantee regarding reimbursement for any service or item.
What should I discuss with my healthcare provider before starting SPRYCEL?
If you take an antacid medicine, take it 2 hours before or 2 hours after your dose of SPRYCEL.
What is SPRYCEL used for?
SPRYCEL ® (dasatinib) is a prescription medicine used to treat: adults with newly diagnosed Philadelphia chromosome–positive (Ph+) chronic myeloid leukemia (CML) in chronic phase . adults with Ph+ CML who no longer benefit from, or did not tolerate, other treatment, including GLEEVEC® (imatinib mesylate)
How long after taking Sprycel can you breastfeed?
Breastfeeding or plan to breastfeed. It is not known if SPRYCEL passes into your breast milk. You should not breastfeed during treatment and for 2 weeks after your last dose of SPRYCEL.
What to do if you miss a Sprycel?
If you miss a dose of SPRYCEL, take your next scheduled dose at your regular time. Do not take two doses at the same time. Call your healthcare provider or your pharmacist if you are not sure what to do.
What are the side effects of spraycel?
headache. skin rash. shortness of breath. tiredness. na usea. muscle pain. The most common side effects of SPRYCEL in children receiving SPRYCEL with chemotherapy include: swelling, pain, and redness of the lining of your mouth, throat, stomach, and bowel (mucositis) low white blood cell counts with fever.
Can you get low blood count with spraccel?
Low blood cell counts: Low blood cell counts are common with SPRYCEL and can be severe, including low red blood cell counts (anemia), low white blood cell counts (neutropenia), and low platelet counts (thrombocytopenia). Your healthcare provider will do blood tests to check your blood cell counts regularly during your treatment with SPRYCEL. Call your healthcare provider right away if you have any of these symptoms during treatment with SPRYCEL:
Does Sprycel cause low red blood cells?
SPRYCEL may cause serious side effects, including those listed below. Call your healthcare provider right away if you have any symptoms of the side effects below, or any other concerns about these side effects: Low blood cell counts: Low blood cell counts are common with SPRYCEL and can be severe, including low red blood cell counts (anemia), ...
What is BMS Access Support?
BMS Access Support ® can provide information about financial assistance programs for eligible patients who have been prescribed SPRYCEL and who need help managing the cost of treatment. The appropriate program will depend on the patient's coverage.
How to contact BMS?
Please contact BMS Access Support at 1-800-861-0048 for details and additional assistance. The Bristol Myers Squibb Patient Assistance Foundation (BMSPAF), a charitable organization, may also provide medicine, free of charge, to eligible, uninsured patients who have an established financial hardship. For more information and eligibility criteria, ...
Does Bristol Myers Squibb guarantee reimbursement?
Bristol Myers Squibb cannot guarantee that a patient will receive assistance. The accurate completion of reimbursement- or coverage-related documentation is the responsibility of the healthcare provider and patient. Bristol Myers Squibb and its agents make no guarantee regarding reimbursement for any service or item.
What is Sprycel used for?
Sprycel (dasatinib) is a member of the BCR-ABL tyrosine kinase inhibitors drug class and is commonly used for Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, and Leukemia.
How much does Sprycel cost?
The cost for Sprycel oral tablet 20 mg is around $8,791 for a supply of 60 tablets, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
How long is the free trial for Sprycel?
Sprycel One Card Free Trial: New eligible commercially insured patients may receive a 1-month FREE trial supply; for additional information contact the program at 800-861-0048.
How much does a free drug card save?
The free Drugs.com Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions.
Is Sprycel a generic?
Sprycel is available as a brand name drug only, a generic version is not yet available. For more information, read about generic Spr ycel av ailability . This Sprycel price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
When is Sprycel approved for use?from news.bms.com
In addition to this pediatric approval, Sprycel is approved for use in children one year of age and older with Ph+ chronic myeloid leukemia (CML) in chronic phase (CP). 1
What is Sprycel used for?from news.bms.com
Sprycel is the first and only second-generation tyrosine kinase inhibitor for pediatric patients for the treatment of newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia in combination with chemotherapy
How long after taking Sprycel can you breastfeed?from sprycel.com
Breastfeeding or plan to breastfeed. It is not known if SPRYCEL passes into your breast milk. You should not breastfeed during treatment and for 2 weeks after your last dose of SPRYCEL.
What is SPRYCEL grade 3/4?from news.bms.com
Treatment with SPRYCEL is associated with severe (NCI CTCAE Grade 3/4) thrombocytopenia, neutropenia, and anemia, which occur earlier and more frequently in patients with advanced phase CML or Ph+ ALL than in patients with chronic phase CML. Myelosuppression was reported in patients with normal baseline laboratory values as well as in patients with pre-existing laboratory abnormalities.
How long does Sprycel last?from news.bms.com
1 The median duration of therapy was 24 months (range 2 to 27 months). 1
How often do you perform CBCs for Ph+?from news.bms.com
During the consolidation blocks of chemotherapy, perform CBCs every 2 days until recovery
How effective is Sprycel?from news.bms.com
The efficacy of Sprycel tablets in combination with chemotherapy was evaluated in a single cohort of the Phase 2, multicenter, single-arm CA180-372 study, which included 78 pediatric patients with newly diagnosed B-cell precursor Ph+ ALL. 1,2 At three years, the study demonstrated an event-free survival (EFS) binary rate of 64.1% (95% confidence interval [CI]: 52.4 to 74.7). 1 Event-free survival is defined as the time from the start of Sprycel to lack of complete response at the end of the third high-risk block, relapse, secondary malignancy or death from any cause.
What is BMS Access Support?from bmsaccesssupport.bmscustomerconnect.com
That's why we offer the BMS Access Support program, which provides resources to help patients understand their insurance coverage and find information on sources of financial support, including co-pay assistance for eligible commercially insured patients.
Is Bristol Myers Squibb merged with Celgene?from bms.com
As of 2019, Bristol Myers Squibb and Celgene have merged. If you or someone you know have possibly experienced a side effect or have a product complaint while taking a legacy Celgene product, please contact us. 1-800-640-7854. (toll free U.S. only) Bristol Myers Squibb COVID-19 Response Line. 1-800-721-8909.
How long does Sprycel treatment last?from sprycel-hcp.com
The median duration of therapy in all 2712 SPRYCEL-treated adult patients was 19.2 months (range 0–93.2 months). Median duration of therapy in:
Who owns the Sprycel logo?from sprycel-hcp.com
SPRYCEL ® and the SPRYCEL logo are trademarks of Bristol-Myers Squibb Company. All other trademarks are property of their respective owners.
How long after taking Sprycel can you breastfeed?from sprycel.com
Breastfeeding or plan to breastfeed. It is not known if SPRYCEL passes into your breast milk. You should not breastfeed during treatment and for 2 weeks after your last dose of SPRYCEL.
How often do you perform CBCs for Ph+?from sprycel-hcp.com
During the consolidation blocks of chemotherapy, perform CBCs every 2 days until recovery
What is BMSPAF in medical terms?from bmspaf.org
The Bristol Myers Squibb Patient Assistance Foundation (BMSPAF) is an independent, charitable organization that helps eligible patients who need temporary help obtaining the medicines listed on this website.
How to contact BMS?from bmsaccesssupport.bmscustomerconnect.com
Please contact BMS Access Support at 1-800-861-0048 for details and additional assistance. The Bristol Myers Squibb Patient Assistance Foundation (BMSPAF), a charitable organization, may also provide medicine, free of charge, to eligible, uninsured patients who have an established financial hardship. For more information and eligibility criteria, ...
What is the number to call for Reblozyl?from bms.com
For more information about how insurance covers REBLOZYL and co-pay assistance for eligible, commercially-insured patients, visit Bristol Myers Squibb Access Support or call 1-800-861-0048. Assistance for Uninsured Patients.
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