Precautions
Bioventus is committed to providing access to SUPARTZ FX, GELSYN-3 and DUROLANE to patients without the financial resources to pay for the treatment by providing Patient Assistance Product at no cost. Patient must be 18 years of age or older. Patient must have a valid prescription.
What is the minimum age to get supartz FX?
SUPARTZ FX is indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics, e.g., acetaminophen. SUPARTZ FX is administered by intra-articular injection once a week (1 week apart) for a total of 5 injections.
What is supartz FX used for?
Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Irritation where Supartz FX (hyaluronate and derivatives injection (knee)) is used. Mild pain, stiffness, or warmth in or by the knee. Swelling where Supartz FX (hyaluronate and derivatives injection (knee)) is used.
What are the side effects of supartz FX (hyaluronate and derivatives)?
Remove joint effusion, if present, before injection of SUPARTZ FX. Take care to remove the tip cap of the syringe and needle aseptically. Inject SUPARTZ FX into the joint through a 22-23 gauge needle. Inject the full 2.5 mL in one knee only. If treatment is bilateral, a separate syringe should be used for each knee.
How do I use supartz FX for knee pain?
What Do I Need to Tell My Doctor Before I Take Supartz FX?
1. If you have an allergy to hyaluronic acid or any other part of Supartz FX (hyaluronate and derivatives injection (knee)). 2. If you are allergic...
What Are Some Things I Need to Know Or Do While I Take Supartz FX?
1. Tell all of your health care providers that you take Supartz FX (hyaluronate and derivatives injection (knee)). This includes your doctors, nurs...
How Is This Medicine (Supartz FX) Best Taken?
Use Supartz FX (hyaluronate and derivatives injection (knee)) as ordered by your doctor. Read all information given to you. Follow all instructions...
What Are Some Side Effects That I Need to Call My Doctor About Right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor o...
What Are Some Other Side Effects of Supartz FX?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help i...
How Do I Store and/or Throw Out Supartz FX?
1. If you need to store Supartz FX (hyaluronate and derivatives injection (knee)) at home, talk with your doctor, nurse, or pharmacist about how to...
What are some other side effects of Supartz FX?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects . Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
How is this medicine (Supartz FX) best taken?
Use Supartz FX (hyaluronate and derivatives injection (knee)) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
How do I store and/or throw out Supartz FX?
If you need to store Supartz FX (hyaluronate and derivatives injection (knee)) at home, talk with your doctor, nurse, or pharmacist about how to store it.
What if you are allergic to Supartz?
If you are allergic to Supartz FX (hyaluronate and derivatives injection (knee)); any part of Supartz FX (hyaluronate and derivatives injection (knee)); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had. If you are using a product that contains ammonium salts or chlorhexidine to clean the area.
How long after Supartz FX can you stand on your feet?
Do not stand on your feet for more than 1 hour at a time during the first 48 hours after getting Supartz FX (hyaluronate and derivatives injection (knee)). Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.
Can you take Supartz FX with a prescription?
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Supartz FX (hyaluronate and derivatives injection (knee)) with all of your drugs and health problems.
Choose SUPARTZ FX and set your own pace
Hyaluronic acid (HA) relieves knee OA pain safely and with fewer side effects than with fewer side effects than NSAIDs (e.g. ibuprofen). 19
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Important Note
The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.
Uses
This medication is used to treat arthritis of the knee. It should be used only after non-drug treatment and simple medication (e.g., acetaminophen) have failed to provide relief.
How To Use
This drug is given by injection into the affected joint by your doctor once a week. Complete the full treatment course, even if you are already feeling better. Follow all instructions. You may not feel clear pain relief until after the last injection in the series.
Side Effects
Injection site pain, itching, swelling, heat or redness of the joint or headache may occur. If these persist or worsen, notify your doctor. Very unlikely but report promptly: fever, bruising, rapid heartbeat, sweating, fainting, chest or stomach pressure/pain, redness of the hands or feet.
Precautions
Before using this drug, tell your doctor your medical history, including: allergies (especially drug allergies), infections and skin diseases in the area of the injection site, knee joint infections. Avoid heavy physical activity or prolonged use of the affected joint (such as jogging, tennis) within 48 hours following the injection.
Drug Interactions
Tell your doctor of all nonprescription or prescription medication you may use, especially of: skin disinfectants that contain ammonium salts. Do not start or stop any medicine without doctor or pharmacist approval.
Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately.
What is SUPARTZ FX?
SUPARTZ FX is indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics, e.g., acetaminophen.
How many times a week is SUPARTZ FX given?
Entry criteria are described for all studies (See Table 2). The treatment regimen consisted of 5 weekly injections in all studies. All patients in these studies (including those injected with the control) received arthrocentesis of the knee prior to an injection of SUPARTZ FX or vehicle (phosphate buffered saline) or, in the German study only, a dilute (1%) form of the SUPARTZ FX formulation. The French study included an additional treatment arm: 3 SUPARTZ FX injections followed by 2 injections of the control per patient. (Table 3 describes the study design and the treatment and follow-up schedules.)
What is Table 6A?
Table 6A: Australia Study Results for WOMAC (Pain, Stiffness, & Disability) as Repeated Measures Analysis of Covariance (ANCOVA) of Mean Reduction from Baseline Over Weeks 6, 10, 14, and 18
How to inject SUPARTZ FX into joint?
Take care to remove the tip cap of the syringe and needle aseptically. Inject SUPARTZ FX into the joint through a 22-23 gauge needle.
How often is SUPARTZ given?
SUPARTZ FX is administered by intra-articular injection once a week (1 week apart) for a total of 5 injections. Some patients may experience benefit with 3 injections given at weekly intervals. This has been noted in a study in which patients treated with three injections were followed for 90 days 4 . Injection of subcutaneous lidocaine or similar local anesthetic may be recommended prior to injection of SUPARTZ FX.
How long does SUPARTZ FX last?
Store in the original packaging below 77°F (25°C). DO NOT FREEZE. Do not use after expiration date indicated on package. Shelf life is 42 months.
Is SUPARTZ FX safe for knees?
The safety and effectiveness of the use of SUPARTZ FX in joints other than the knee have not been established.