What kind of drug is Velcade?
Velcade Prices, Coupons and Patient Assistance Programs. Velcade (bortezomib) is a member of the proteasome inhibitors drug class and is commonly used for Lymphoma, Mantle Cell Lymphoma and Multiple Myeloma. This Velcade price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
How much does Velcade cost without insurance?
Velcade Prices. The cost for Velcade injectable powder for injection 3.5 mg is around $1,682 for a supply of 1 powder for injection, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
What should I do if I have side effects from Velcade?
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. have liver disease or kidney disease. If you are on dialysis, your doctor will administer VELCADE after the dialysis procedure.
What happens if my partner gets pregnant during treatment with Velcade?
Males with female partners of reproductive potential must use effective contraception during treatment with VELCADE and for four months following the last dose of VELCADE. Tell your healthcare provider right away if you or your partner become pregnant while you are receiving VELCADE or within seven months following the last dose.
What is VELCADE reimbursement assistance program?
This program provides brand name medications at no or low cost.
Is there an alternative to VELCADE?
Two separate clinical trials presented at ASCO 2012 suggest that carfilzomib (Kyprolis) would be a safe and effective alternative to bortezomib (Velcade) for the treatment of multiple myeloma.
How long is VELCADE treatment for multiple myeloma?
Velcade is given for nine 6-week treatment cycles.
How does VELCADE make you feel?
Nerve problems (peripheral neuropathy). Velcade can cause damage to the nerves, a condition called peripheral neuropathy. You may feel muscle weakness, tingling, burning, pain, and loss of feeling in your hands and feet, any of which can be severe. Tell your doctor if you notice any of these symptoms.
Why is dexamethasone used for multiple myeloma?
Dexamethasone and the other steroids are useful in myeloma treatment because they can stop white blood cells from traveling to areas where cancerous myeloma cells are causing damage. This decreases the amount of swelling or inflammation in those areas and relieves associated pain and pressure.
What is the protocol for multiple myeloma?
All transplant-eligible multiple myeloma patients should receive a triplet induction therapy (immunomodulatory agents, proteasome inhibitor and dexamethasone). Bortezomib with lenalidomide and dexamethasone is the most commonly used regimen.
How much does VELCADE cost per month?
For instance, common multiple myeloma drug Bortezomib (Velcade)[5] , which is administered intravenously, costs $4,000-$8,000 per month, depending on dosing, while lenalidomide (Revlimid)[6] , costs $7,900 per month at a 21-out-of-28-day dosing.
Do you lose your hair with VELCADE?
Hair loss. Hair loss isn't a direct side effect of Velcade, but it may be a side effect of other drugs used with Velcade. For example, hair loss may occur in people using Velcade with cyclophosphamide, which is a cytotoxic drug. (Cytotoxic drugs work by killing cells.)
Does VELCADE make you tired?
VELCADE may cause fatigue, dizziness, fainting (syncope), or lightheadedness when you sit or stand up. You should not drive or operate machinery if you experience any of these symptoms.
How fast does Velcade work?
Data from SUMMIT and APEX suggest that in most patients response to treatment is quick with the median time to a first response 1.3 months (Richardson et al 2003, 2005a).
How long is Velcade treatment?
VELCADE is given intravenously twice a week for 2 weeks followed by a 10-day rest period. This can be repeated for up to 6 cycles.
How many cycles of Velcade are there?
The recommended starting dose of Velcade for untreated mantle cell lymphoma is 1.3 mg/m2. Your doctor will give you this dose by IV injection for 6 treatment cycles. Each cycle will last 3 weeks. Typically, Velcade is prescribed as part of a “VcR-CAP” drug regimen or cycle.
Is Velcade and Revlimid the same?
Revlimid (Lenalidomide) However, it frequently causes burning, tingling, and numbness in the hands and feet. Velcade (bortezomib) improved response and delayed cancer progression in multiple myeloma and mantle cell lymphoma. First-choice treatment for multiple myeloma, and effective treatment for mantle cell lymphoma.
Is kyprolis the same as Velcade?
"Based on these data, we now know that KYPROLIS not only significantly extended progression-free survival compared to Velcade, but also overall survival, making it a clinically meaningful advance in the treatment of relapsed or refractory multiple myeloma."
Is Ninlaro the same as Velcade?
Bottom line: Ninlaro is used to treat multiple myeloma and Velcade can be used to treat multiple myeloma and mantle cell lymphoma. Ninlaro is a convenient capsule taken weekly, Velcade is an injection given twice weekly or weekly. Ninlaro has less side effects, that are not as severe.
Is Velcade a Revlimid?
The addition of the proteasome inhibitor Velcade® (bortezomib) to the treatment combination Revlimid® (lenalidomide) plus dexamethasone improves survival when used as initial therapy in multiple myeloma among patients who do not intend to immediately undergo a stem cell transplant according to clinical trial results ...
How long after velcade can you use birth control?
Females should use effective birth control during treatment and for at least seven months after the final dose of VELCADE. If using hormonal contraceptives (for example, the pill), an additional barrier method of contraception (for example, diaphragm or condom) must be used.
Does Velcade lower blood pressure?
VELCADE can cause a drop in blood pressure. Tell your doctor if you have low blood pressure, feel dizzy, or feel as though you might faint. If you are taking drugs that lower blood pressure, your medications might need to be adjusted. If you are not drinking enough liquids, your doctor may need to administer IV fluids.
Does Velcade cause heart problems?
Treatment with VELCADE can cause or worsen heart rhythm problems and heart failure. Your doctor may closely monitor you if you have, or are at risk for, heart disease. Tell your doctor if you experience chest pressure or pain, palpitations, swelling of your ankles or feet, or shortness of breath.
Can Velcade cause nerve damage?
VELCADE can cause serious side effects, including: Nerve problems (peripheral neuropathy). VELCADE can cause damage to the nerves, a condition called peripheral neuropathy. You may feel muscle weakness, tingling, burning, pain, and loss of feeling in your hands and feet, any of which can be severe.
Can velcae cause low neutrophils?
Lowered white blood cells (neutropenia). VELCADE can cause low levels of neutrophils which are a type of white blood cells that help to fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or believe you have an infection.
Can Velcade be stopped?
Treatment with VELCADE should be stopped in cases of PRES. It is not known whether restarting VELCADE therapy in patients previously experiencing this complication is safe. Stomach and Intestinal problems (gastrointestinal toxicity). VELCADE treatment can cause nausea, vomiting, diarrhea, and constipation.
An Alternative to Velcade Patient Assistance Programs
If you or your loved one is in this difficult situation, Welcome Funds may have a solution. We help multiple myeloma patients and their families relieve financial stress by converting their life insurance benefits into a lump sum cash payment that can be used as a personal health care fund.
About Welcome Funds
Founded in 2000, Welcome Funds has helped thousands of Americans qualify for a life insurance settlement.
How is VELCADE administered?
It is administered by a healthcare professional as an injection into your vein (intravenously, or IV) or under your skin (subcutaneously, or SC).
What are the possible side effects of VELCADE?
Tell your healthcare provider if you get any new or worsening symptoms, including: muscle weakness, tingling, burning, pain, and loss of feeling in your hands and feet, any of which can be severe. Your doctor may change the dose and/or schedule of VELCADE or stop it altogether. If you have peripheral neuropathy before starting VELCADE, your doctor could consider giving you VELCADE subcutaneously.
What should I avoid while taking VELCADE?
VELCADE may cause fatigue, dizziness, fainting (syncope), or lightheadedness when you sit or stand up. You should not drive or operate machinery if you experience any of these symptoms.
How long after velcae can you get pregnant?
Females should use effective birth control during treatment and for at least seven months after the final dose of VELCADE. If using hormonal contraceptives (for example, the pill), an additional barrier method of contraception (for example, diaphragm or condom) must be used. Males should use effective contraception during treatment with VELCADE and for four months following treatment. Tell your doctor immediately if you think you are pregnant. Do not breastfeed during treatment with VELCADE and for two months after your final dose of VELCADE.
What to do if you feel dizzy and low blood pressure?
If you are taking drugs that lower blood pressure, your medications might need to be adjusted . If you are not drinking enough liquids, your doctor may need to administer IV fluids. Heart problems (cardiac toxicity).
Can velcade be administered to spinal fluid?
It is administered by a healthcare professional as an injection into your vein (intravenously, or IV) or under your skin (subcutaneously, or SC). VELCADE must not be administered into your spinal fluid (intrathecally).
Can you restart Velcade?
It is not known whether restarting VELCADE therapy in patients previously experiencing this complication is safe. Hematologic disease (Thrombotic Microangiopathy, TMA). VELCADE can lead to the formation of blood clots in small blood vessels.
Important Note
The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.
Uses
This medication is a cancer chemotherapy drug used to treat certain types of tumors (e.g., multiple myeloma). It blocks certain proteins which helps to slow the growth and spread of the cancer.
How To Use
This medication is given by injection into a vein (IV) by a healthcare professional. The dosage is based on your medical condition and response to therapy. Follow all directions for proper mixing. Before using, check this medication visually for particles or discoloration. If either is present, do not use the liquid.
Side Effects
Dizziness, lightheadedness, nausea, vomiting, loss of appetite, diarrhea, constipation, tiredness, weakness, or blurred vision may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
Precautions
Before using this medication, tell your doctor or pharmacist your medical history, especially of: nerve sensation problems (e.g., peripheral neuropathy), low blood pressure, loss of body fluids (dehydration), diabetes, liver disease, severe kidney disease, any allergies (especially to boron or mannitol).
Drug Interactions
Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: medications to treat high blood pressure, oral anti-diabetic drugs, other drugs that may cause peripheral neuropathy (e.g., amiodarone, isoniazid, nitrofurantoin, certain anti-virals such as acyclovir, ritonavir, zidovudine).
Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include: fainting or persistent fever.
What is velcade used for?
VELCADE belongs to a class of medicines called proteasome inhibitors. It is approved by the FDA for the treatment of multiple myeloma and mantle cell lymphoma. VELCADE has been studied in many important clinical trials.
What are the side effects of Velcade?
The most common side effects reported by people receiving VELCADE in this study included abnormal blood cell counts; numbness, tingling, burning, or weakness in hands or feet; nausea; diarrhea; and nerve pain.
What is the treatment for mantle cell lymphoma?
In a clinical trial, people with mantle cell lymphoma received either VELCADE or vincristine along with rituximab, cyclophosphamide, doxorubicin, and prednisone
What is velcade injection?
VELCADE is an injection that is given intravenously (into your vein) or subcutaneously (under your skin) by a healthcare professional.
How does Velcade work?
As a targeted therapy, VELCADE works by blocking or slowing down the action of proteasomes inside cells. The function of proteasomes is to break down proteins in both healthy and cancerous cells.
How long do you have to wait between Velcade doses?
You must wait at least 3 days between VELCADE doses.
How long does Velcade therapy last?
In a study, half of the people taking VELCADE-based therapy stayed on VELCADE for at least 50 weeks out of a planned 54 weeks
What is Velcade used for?
Velcade (bortezomib) is a member of the proteasome inhibitors drug class and is commonly used for Lymphoma, Mantle Cell Lymphoma, and Multiple Myeloma.
How much does a free drug card save?
The free Drugs.com Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions.
Is Velcade a generic drug?
Velcade is available as a brand name drug only, a generic version is not yet available. For more information, read about generic Velcade availability . This Velcade price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
