What is VELCADE reimbursement assistance program?
This program provides brand name medications at no or low cost.
How long is VELCADE treatment for multiple myeloma?
Velcade is given for nine 6-week treatment cycles.
How is VELCADE billed?
HCPCS code: J9041– Injection, bortezomib (Velcade), 0.1 mg; 1 billable unit = 0.1 mg.
How often is VELCADE given for multiple myeloma?
Dosage for multiple myeloma Velcade is typically given in nine treatment cycles, with each cycle being 6 weeks long. There must be at least 3 days between your Velcade injections. During the first 4 days of every cycle, you'll most likely take two other drugs: Alkeran (melphalan) and Rayos (prednisone).
How much does VELCADE cost per month?
For instance, common multiple myeloma drug Bortezomib (Velcade)[5] , which is administered intravenously, costs $4,000-$8,000 per month, depending on dosing, while lenalidomide (Revlimid)[6] , costs $7,900 per month at a 21-out-of-28-day dosing.
Do you lose your hair with VELCADE?
Hair loss. Hair loss isn't a direct side effect of Velcade, but it may be a side effect of other drugs used with Velcade. For example, hair loss may occur in people using Velcade with cyclophosphamide, which is a cytotoxic drug. (Cytotoxic drugs work by killing cells.)
How long can you take Velcade?
VELCADE is given intravenously twice a week for 2 weeks followed by a 10-day rest period. This can be repeated for up to 6 cycles.
Is Velcade considered chemotherapy?
VELCADE (bortezomib) is a type of chemotherapy called a targeted therapy. VELCADE belongs to a class of medicines called proteasome inhibitors. It is approved by the FDA for the treatment of multiple myeloma and mantle cell lymphoma. VELCADE has been studied in many important clinical trials.
Is there a generic for Velcade?
Fresenius Kabi has introduced bortezomib, a new generic equivalent to Takeda's Velcade, which is indicated to treat adults with multiple myeloma and mantle cell lymphoma. The generic is available in a 3.5 mg per 10 mL single-dose for subcutaneous or intravenous use.
Does VELCADE make you tired?
VELCADE may cause fatigue, dizziness, fainting (syncope), or lightheadedness when you sit or stand up. You should not drive or operate machinery if you experience any of these symptoms.
Does VELCADE cause bone pain?
bone or joint pain, sleep problems (insomnia), rash or itching, or. skin irritation where the medicine was injected.
What does VELCADE do for multiple myeloma?
Generic Name: bortezomib This medication is used to treat certain types of cancer (such as multiple myeloma, mantle cell lymphoma). It works by slowing or stopping the growth of cancer cells.
How long do you take Velcade?
VELCADE is given intravenously twice a week for 2 weeks followed by a 10-day rest period. This can be repeated for up to 6 cycles.
How long is a cycle of Velcade?
VELCADE is administered twice weekly for two weeks (Days 1, 4, 8, and 11) followed by a ten day rest period on Days 12 to 21. For patients with a response first documented at Cycle 6, two additional VcR-CAP cycles are recommended. At least 72 hours should elapse between consecutive doses of VELCADE.
Is Velcade considered chemotherapy?
VELCADE (bortezomib) is a type of chemotherapy called a targeted therapy. VELCADE belongs to a class of medicines called proteasome inhibitors. It is approved by the FDA for the treatment of multiple myeloma and mantle cell lymphoma. VELCADE has been studied in many important clinical trials.
How fast does Velcade work?
Data from SUMMIT and APEX suggest that in most patients response to treatment is quick with the median time to a first response 1.3 months (Richardson et al 2003, 2005a).
An Alternative to Velcade Patient Assistance Programs
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We can help keep you up to date and give you the assistance and information you need.
Getting involved with your treatment
At Takeda Oncology, we believe that being an active participant in your treatment plan helps you get more out of your doctors’ appointments. And that starts with asking questions. Lots of them.
Multiple Myeloma Events
Sign up for online and in-person events where you can listen to leading medical experts discuss multiple myeloma treatment options, have your questions answered, and connect with a community of people affected by multiple myeloma.
How is VELCADE administered?
It is administered by a healthcare professional as an injection into your vein (intravenously, or IV) or under your skin (subcutaneously, or SC).
What are the possible side effects of VELCADE?
Tell your healthcare provider if you get any new or worsening symptoms, including: muscle weakness, tingling, burning, pain, and loss of feeling in your hands and feet, any of which can be severe. Your doctor may change the dose and/or schedule of VELCADE or stop it altogether. If you have peripheral neuropathy before starting VELCADE, your doctor could consider giving you VELCADE subcutaneously.
What should I avoid while taking VELCADE?
VELCADE may cause fatigue, dizziness, fainting (syncope), or lightheadedness when you sit or stand up. You should not drive or operate machinery if you experience any of these symptoms.
How long after velcae can you get pregnant?
Females should use effective birth control during treatment and for at least seven months after the final dose of VELCADE. If using hormonal contraceptives (for example, the pill), an additional barrier method of contraception (for example, diaphragm or condom) must be used. Males should use effective contraception during treatment with VELCADE and for four months following treatment. Tell your doctor immediately if you think you are pregnant. Do not breastfeed during treatment with VELCADE and for two months after your final dose of VELCADE.
Can velcade be administered to spinal fluid?
It is administered by a healthcare professional as an injection into your vein (intravenously, or IV) or under your skin (subcutaneously, or SC). VELCADE must not be administered into your spinal fluid (intrathecally).
Can you restart Velcade?
It is not known whether restarting VELCADE therapy in patients previously experiencing this complication is safe. Hematologic disease (Thrombotic Microangiopathy, TMA). VELCADE can lead to the formation of blood clots in small blood vessels.
Can Velcade cause lung problems?
Lung problems (pulmonary toxicity). There have been reports of lung disorders in people receiving VELCADE. Some of these events have been fatal. Tell your doctor if you experience any cough, shortness of breath, wheezing, or difficulty breathing.
How long after velcade can you use birth control?
Females should use effective birth control during treatment and for at least seven months after the final dose of VELCADE. If using hormonal contraceptives (for example, the pill), an additional barrier method of contraception (for example, diaphragm or condom) must be used.
Does Velcade lower blood pressure?
VELCADE can cause a drop in blood pressure. Tell your doctor if you have low blood pressure, feel dizzy, or feel as though you might faint. If you are taking drugs that lower blood pressure, your medications might need to be adjusted. If you are not drinking enough liquids, your doctor may need to administer IV fluids.
Does Velcade cause heart problems?
Treatment with VELCADE can cause or worsen heart rhythm problems and heart failure. Your doctor may closely monitor you if you have, or are at risk for, heart disease. Tell your doctor if you experience chest pressure or pain, palpitations, swelling of your ankles or feet, or shortness of breath.
Can Velcade cause nerve damage?
VELCADE can cause serious side effects, including: Nerve problems (peripheral neuropathy). VELCADE can cause damage to the nerves, a condition called peripheral neuropathy. You may feel muscle weakness, tingling, burning, pain, and loss of feeling in your hands and feet, any of which can be severe.
Can velcae cause low neutrophils?
Lowered white blood cells (neutropenia). VELCADE can cause low levels of neutrophils which are a type of white blood cells that help to fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or believe you have an infection.
Can Velcade be stopped?
Treatment with VELCADE should be stopped in cases of PRES. It is not known whether restarting VELCADE therapy in patients previously experiencing this complication is safe. Stomach and Intestinal problems (gastrointestinal toxicity). VELCADE treatment can cause nausea, vomiting, diarrhea, and constipation.
What is Velcade used for?
Velcade (bortezomib) is a member of the proteasome inhibitors drug class and is commonly used for Lymphoma, Mantle Cell Lymphoma, and Multiple Myeloma.
How much does a free drug card save?
The free Drugs.com Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions.
Is Velcade a generic drug?
Velcade is available as a brand name drug only, a generic version is not yet available. For more information, read about generic Velcade availability . This Velcade price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
What is velcade used for?
VELCADE belongs to a class of medicines called proteasome inhibitors. It is approved by the FDA for the treatment of multiple myeloma and mantle cell lymphoma. VELCADE has been studied in many important clinical trials.
What is velcade injection?
VELCADE is an injection that is given intravenously (into your vein) or subcutaneously (under your skin) by a healthcare professional.
What is the treatment for mantle cell lymphoma?
In a clinical trial, people with mantle cell lymphoma received either VELCADE or vincristine along with rituximab, cyclophosphamide, doxorubicin, and prednisone
How does Velcade work?
As a targeted therapy, VELCADE works by blocking or slowing down the action of proteasomes inside cells. The function of proteasomes is to break down proteins in both healthy and cancerous cells.
How long do you have to wait between Velcade doses?
You must wait at least 3 days between VELCADE doses.
How long does Velcade therapy last?
In a study, half of the people taking VELCADE-based therapy stayed on VELCADE for at least 50 weeks out of a planned 54 weeks
How long does it take for Velcade to respond to treatment?
In this study of VELCADE, in previously untreated people, some people had their best response as early as 6 weeks. Others continued to respond after 6 months of treatment. If you don’t respond early, don’t be discouraged. It’s important to stick with your treatment plan if you and your doctor decide it’s right for you.
Important Note
The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.
Uses
This medication is a cancer chemotherapy drug used to treat certain types of tumors (e.g., multiple myeloma). It blocks certain proteins which helps to slow the growth and spread of the cancer.
How To Use
This medication is given by injection into a vein (IV) by a healthcare professional. The dosage is based on your medical condition and response to therapy. Follow all directions for proper mixing. Before using, check this medication visually for particles or discoloration. If either is present, do not use the liquid.
Side Effects
Dizziness, lightheadedness, nausea, vomiting, loss of appetite, diarrhea, constipation, tiredness, weakness, or blurred vision may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
Precautions
Before using this medication, tell your doctor or pharmacist your medical history, especially of: nerve sensation problems (e.g., peripheral neuropathy), low blood pressure, loss of body fluids (dehydration), diabetes, liver disease, severe kidney disease, any allergies (especially to boron or mannitol).
Drug Interactions
Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: medications to treat high blood pressure, oral anti-diabetic drugs, other drugs that may cause peripheral neuropathy (e.g., amiodarone, isoniazid, nitrofurantoin, certain anti-virals such as acyclovir, ritonavir, zidovudine).
Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include: fainting or persistent fever.
