Does Vosevi come with co-pay insurance coupons?
Gilead, the manufacturer of Vosevi has a special patient assistance program called Support Path™ that may assist with co-pay insurance coupons or make Vosevi available at no charge for eligible and qualified uninsured patients.
Where can I find additional information about Vosevi support path?
For additional information about VOSEVI Support Path®, call 1-855-7-MYPATH (1-855-769-7284).
What kind of drug is Vosevi?
Vosevi Prices, Coupons and Patient Assistance Programs. Vosevi (sofosbuvir/velpatasvir/voxilaprevir) is a member of the antiviral combinations drug class and is commonly used for Hepatitis C.
Does Vosevi interact with other medications or foods?
VOSEVI and certain other medicines may affect each other, or may cause side effects. VOSEVI contains sofosbuvir, the medicine that has helped transform Hep C treatment, combined with 2 additional medicines—creating a highly effective Hep C treatment. With VOSEVI, treatment is one pill, once a day, taken with food for 12 weeks.
What is VOSEVI used for?
VOSEVI is a prescription medicine used to treat adults with chronic (lasting a long time) hepatitis C (Hep C) genotype 1, 2, 3, 4, 5, or 6 infection with or without cirrhosis (compensated) who have previously been treated with a Hep C regimen containing an NS5A inhibitor.
How effective is VOSEVI?
It reflects how long the hepatitis C virus is undetectable in the blood. An overall SVR12 rate of 96% was reported for all genotypes. This means that Vosevi cured 96% of people overall.
How long is VOSEVI treatment?
VOSEVI has a simple treatment regimen that's one pill, once a day, taken with food for 12 weeks.
What is support path Patient Assistance Program?
Support Path is a program that can help patients get started on Gilead and Asegua treatments. Call now to connect live with a Support Path Program Navigator at. 1-855-7-MYPATH (1-855-769-7284) Monday – Friday, 9 am to 8 pm ET.
What are the side effects of VOSEVI?
The most common side effects of VOSEVI include headache, tiredness, diarrhea, and nausea.
What is the cost of VOSEVI?
Vosevi costs approximately $930 per tablet. A 4-week treatment course is approximately $26,026, an 8-week course is approximately $52,052 and a 12-week course is $78,078.
Will I feel better after hep C treatment?
Since hepatitis C doesn't always cause any symptoms, you may not feel any different after being cured. If you were experiencing symptoms — fatigue is the common one — you should start to feel stronger and more energetic, which should continue to improve after you finish treatment, says Massoud.
How long can HCV patients live?
An acute HCV infection does not lead to a life-threatening disease and usually goes away after six months without any treatment. On the other hand, a chronic HCV infection can cause severe conditions, like liver cirrhosis, within 20 years after initial infection.
How long does it take for liver to heal after hep C treatment?
If someone's liver has mild to moderate damage (fibrosis) and the hepatitis C virus is eliminated and no other liver damage effects are occurring, the liver can regenerate and heal within a few days up to 3-6 months, approximately.
Does Gilead copay card expire?
Have no fear, the cards are not expired, and you can still fill your PrEP prescription.
Can I get Mavyret free?
You may be eligible to receive free MAVYRET if you: Have been prescribed MAVYRET. Have limited or no health insurance coverage. Live in the United States.
What are the side effects of Epclusa?
Epclusa common side effectsfatigue.headache.nausea.insomnia (trouble sleeping)muscle weakness.irritability.
What is the success rate of hep C treatment?
Hepatitis C treatment can cure more than 90 percent of hepatitis C cases, but testing is a critical first step. It's estimated 40 percent of people with hepatitis C in the U.S. from 2015-2018 were unaware of their infection.
What is the best drug to cure hep C?
Hepatitis C is treated using direct-acting antiviral (DAA) tablets. DAA tablets are the safest and most effective medicines for treating hepatitis C. They're highly effective at clearing the infection in more than 90% of people. The tablets are taken for 8 to 12 weeks.
How long after hep C treatment will I feel better?
The healing process takes time, patience and effort. Most hep C patients report seeing treatment side effects subsiding within a few months or longer. Often it takes six months to a year to regain full energy and feel well. Some patients have reported side effects lingering for longer periods of time.
Can you drink alcohol while taking VOSEVI?
You should avoid drinking alcohol while you're taking Vosevi to treat hepatitis C. Drinking alcohol could cause further damage to your liver. It can also increase your risk for getting Vosevi side effects such as headaches, diarrhea, nausea, and fatigue (lack of energy).
What is Vosevi?from drugs.com
Vosevi contains a combination of sofosbuvir, velpatasvir, and voxilaprevir. Sofosbuvir, velpatasvir, and voxilaprevir are antiviral medications that prevent hepatitis C virus (HCV) from multiplying in your body.
What are the symptoms of allergic reaction to Vosevi?from drugs.com
Get emergency medical help if you have signs of an allergic reaction to Vosevi: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
What other drugs will affect Vosevi?from drugs.com
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
What is the effect of voxilaprevir on HCV replication?from pubchem.ncbi.nlm.nih.gov
Voxilaprevir is a direct-acting antiviral agent that targets viral NS3/4A protein and causes a decrease in serum HCV RNA levels. It disrupts HCV replication by specifically inhibiting the critical functions of NS3/4A protein in the replication complex.
How much is voxilaprevir bound to plasma?from pubchem.ncbi.nlm.nih.gov
Voxilaprevir is more than 99% bound to human plasma proteins.
What is the maximum concentration of voxilaprevir?from pubchem.ncbi.nlm.nih.gov
When provided as the fixed dose combination product Vosevi with [DB08934] and [DB11613], voxilaprevir reaches a maximum concentration (Cmax) of 192 ng/mL at a maximum time (Tmax) of 4 hours post-dose.
How long before antacids to take Vosevi?from pubchem.ncbi.nlm.nih.gov
Take separate from antacids. Take Vosevi ( sofosbuvir, velpatasvir, and voxilaprevir) at least 4 hours before or after antacids. Antacids have been shown to reduce the serum levels of velpatasvir and may not impact voxilaprevir.
What is Vosevi?from drugs.com
Vosevi contains a combination of sofosbuvir, velpatasvir, and voxilaprevir. Sofosbuvir, velpatasvir, and voxilaprevir are antiviral medications that prevent hepatitis C virus (HCV) from multiplying in your body.
What are the symptoms of allergic reaction to Vosevi?from drugs.com
Get emergency medical help if you have signs of an allergic reaction to Vosevi: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
What other drugs will affect Vosevi?from drugs.com
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
How long does Vosevi last?from drugs.com
Vosevi is usually taken once per day for 12 weeks. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
How long should I take Vosevi?from drugs.com
Take Vosevi for the entire treatment period as directed by your doctor.
Can you share Vosevi with other people?from drugs.com
Vosevi treats specific genotypes of hepatitis C, and only in certain people. Use only the medications prescribed for you. Do not share your medicine with other people. Vosevi is sometimes used in people who also have HIV.
Can you take Vosevi if you are allergic to rifampin?from drugs.com
You should not use Vosevi if you are allergic to sofosbuvir, velpatasvir, or voxilaprevir. Do not take this medication if you are also taking rifampin. Tell your doctor about all your medical conditions.
What is Vosevi used for?
Vosevi (sofosbuvir/velpatasvir/voxilaprevir) is a member of the antiviral combinations drug class and is commonly used for Hepatitis C.
How much does a free drug card save?
The free Drugs.com Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions.
Do you have to have a Social Security number to be a patient?
The patient must also be a US resident with a Social Security Number.
Is Vosevi a generic?
Vosevi is available as a brand name drug only, a generic version is not yet available. For more information, read about generic Vosevi availability . This Vosevi price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
What is a vosevi?
Vosevi is a name for a combination tablet containing sofosbuvir, velpatasvir, and voxilaprevir that may be used to treat chronic hepatitis C virus (HCV) infection in people who have already undergone treatment with certain other HCV medications . Because Vosevi contains three different active ingredients (sofosbuvir, velpatasvir, ...
What are the side effects of Vosevi?
Side effects are typically mild and may include headache, fatigue, itching, a lack of energy, or gastrointestinal side effects and cure rates range from 91% to 100% depending on the HCV genotype. 5. Tips. Before you start taking Vosevi your doctor will test you for hepatitis B virus (HBV) infection.
What are the symptoms of Vosevi?
Seek urgent medical attention if you develop a very slow heartbeat, feel faint or unwell, or experience symptoms such as dizziness or lightheadedness, weakness, excessive tiredness, shortness of breath, chest pains, confusion, or memory problems. There is limited data as to the effects of Vosevi on a developing fetus.
What is the cure rate for vosevi?
Side effects are typically mild and may include headache, fatigue, itching, a lack of energy, or gastrointestinal side effects and cure rates range from 91% to 100% depending on the HCV genotype.
How long should I take Vosevi?
Take Vosevi for 12 weeks or for the duration that is recommended by your physician. Take Vosevi with food. Food increases how much Vosevi is absorbed, which increases its effectiveness. Tell your doctor if you take any other medications or supplements, including those purchased from a supermarket or health store.
How many antiviral medications are in Vosevi?
Vosevi contains three antiviral medications: sofosbuvir 400mg, velpatasvir 100mg, and voxilaprevir 100mg. These have been combined into one tablet so that only one tablet needs to be taken once daily. Vosevi is a stand-alone treatment. No other HCV medications need to be taken alongside Vosevi.
Is Vosevi generic?
There is currently no generic for Vosevi. Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects.
How much does the Vosevi coupon cover?
The VOSEVI Co-pay Coupon Program will cover the out-of-pocket costs of your VOSEVI prescriptions up to a maximum of 25% of the catalog price of 12 weeks (3 bottles) of VOSEVI. See Terms and Conditions below.
How old do you have to be to use Vosevi?
territories. Product must be dispensed in the U.S., Puerto Rico, or U.S. territories. Coupon user must be at least 18 years old to use the Coupon for themselves or on behalf of a minor.
How many mg of Vosevi?from accessdata.fda.gov
Each Vosevi tablet contains 400 mg of sofosbuvir, 100 mg of velpatasvir, and 100 mg of voxilaprevir. The tablets are beige, capsule-shaped, film-coated, and debossed with "GSI" on one side and " " on the other side.
What is Vosevi used for?from drugs.com
Vosevi is indicated for the treatment of adult patients with chronic hepatitis C virus (HCV) infection without cirrhosis or with compensated cirrhosis (Child-Pugh A) who have [see Dosage and Administration (2.2) and Clinical Studies (14) ]:
What is a vesiv?from accessdata.fda.gov
VOSEVI is a fixed-dose combination of sofosbuvir, a hepatitis C virus (HCV) nucleotide analog NS5B polymerase inhibitor, velpatasvir, an HCV NS5A inhibitor, and voxilaprevir, an HCV NS3/4A protease inhibitor , and is indicated for the treatment of adult patients with chronic HCV infection without cirrhosis or with compensated cirrhosis (Child-Pugh A) who have (1, 2.2, 14): genotype 1, 2, 3, 4, 5, or 6 infection and have previously been
How much Vosevi is in a tablet?from drugs.com
The recommended dosage of Vosevi is one tablet, taken orally, once daily with food [see Clinical Pharmacology (12.3) ]. One tablet of Vosevi contains 400 mg of sofosbuvir, 100 mg of velpatasvir, and 100 mg of voxilaprevir. Table 1 shows the recommended treatment regimen and duration based on patient population.
How many mg of voxilaprevir are in a vesiv?from accessdata.fda.gov
Each VOSEVI tablet contains 400 mg of sofosbuvir, 100 mg of velpatasvir, and 100 mg of voxilaprevir. The tablets are beige, capsule-shaped, film-coated, and debossed with
How much Velpatasvir is given to pregnant mice?from drugs.com
Velpatasvir: Velpatasvir was administered orally to pregnant mice (up to 1000 mg/kg/day), rats (up to 200 mg/kg/day) and rabbits (up to 300 mg/kg/day) from gestation days 6 to 15, 6 to 17, and 7 to 20, respectively, and also to rats (oral doses up to 200 mg/kg) on gestation day 6 to lactation/post-partum day 20.
How often should I take Vosevi?from drugs.com
Advise patients to take Vosevi once daily on a regular dosing schedule with food. Inform patients that it is important not to miss or skip doses and to take Vosevi for the duration that is recommended by the physician.
What is the support path program?from gilead.com
The Support Path program helps patients understand their coverage and identify financial support options to access their Gilead HCV medicine. The program offerings include:
What is the advancing access program?from gilead.com
Advancing Access patient assistance program, which provides Gilead medicines at no cost for qualified patients that meet the program’s eligibility criteria.
Does Zydelig provide patient assistance?from gilead.com
Referral to the Zydelig patient assistance program, which provides Zydelig at no cost for qualified patients that meet the program’s eligibility criteria.
Where were patients treated?from hcp.epclusa.com
Patients were treated in different clinical settings, including university hospitals, academic centers, community centers, outpatient clinics and private practices. Treatment and patient monitoring were based on local clinical practice and standard of care, at the discretion of the treating physician.
What is the dosage of EpclUSA?from hcp.epclusa.com
EPCLUSA (sofosbuvir 400 mg/velpatasvir 100 mg, 200 mg/50 mg tablets; 200 mg/50 mg, 150 mg/37.5 mg oral pellets) is indicated for the treatment of patients 3 years of age and older with chronic hepatitis C virus (HCV) genotype 1-6 infection without cirrhosis or with compensated cirrhosis and in combination with ribavirin for those with decompensated cirrhosis.
Can EPCLUSA connect to support path?from epclusa.com
Once you and your healthcare provider have decided on treatment with EPCLUSA, EPCLUSA Educators can connect you to Support Path ® for financial assistance.
Does nurse support take place with a physician?from hcp.epclusa.com
Nurse support does not take the place of talking with a physician.
Can you take EPCLUSA with topotecan?from hcp.epclusa.com
Coadministration of EPCLUSA is not recommended with topotecan due to increased concentrations of topotecan.
How It Works
Upsides
- Vosevi may be used to treat adults with HCV genotypes 1, 2, 3, 4, 5, or 6 infection (without cirrhosis, or with compensated cirrhosis) that has previously been treated with an NS5A inhibitor regimen.
- Vosevi may also be used to treat adults HCV genotype 1a or 4 infection (without cirrhosis, or with compensated cirrhosis) that has previously been treated with a sofosbuvir regimen with…
- Vosevi may be used to treat adults with HCV genotypes 1, 2, 3, 4, 5, or 6 infection (without cirrhosis, or with compensated cirrhosis) that has previously been treated with an NS5A inhibitor regimen.
- Vosevi may also be used to treat adults HCV genotype 1a or 4 infection (without cirrhosis, or with compensated cirrhosis) that has previously been treated with a sofosbuvir regimen without an NS5A...
- Vosevi contains three antiviral medications: sofosbuvir 400mg, velpatasvir 100mg, and voxilaprevir 100mg. These have been combined into one tablet so that only one tablet needs to be taken once daily.
- Vosevi is a stand-alone treatment. No other HCV medications need to be taken alongside Vo…
Downsides
- If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: 1. Vosevi is usually well-tolerated, but the most common side effects reported include headache, fatigue, itching, asthenia (lack of energy), nausea or an upset stomach, diarrhea, or difficulty sleeping. 2. Reactivation of h…
Bottom Line
- Vosevi is a stand-alone combination antiviral treatment that may be used to treat HCV infection of genotypes 1 through 6 in adults who have been previously treated with certain other antiviral medications. Side effects are typically mild and may include headache, fatigue, itching, a lack of energy, or gastrointestinal side effects and cure rates range from 91% to 100% depending on th…
Tips
- Before you start taking Vosevi your doctor will test you for hepatitis B virus (HBV) infection. This is because treating HCV may reactivate an underlying hepatitis B infection (HBV). Any underlying...
- Vosevi is best taken at the same time every day. Take Vosevi for 12 weeks or for the duration that is recommended by your physician.
- Before you start taking Vosevi your doctor will test you for hepatitis B virus (HBV) infection. This is because treating HCV may reactivate an underlying hepatitis B infection (HBV). Any underlying...
- Vosevi is best taken at the same time every day. Take Vosevi for 12 weeks or for the duration that is recommended by your physician.
- Take Vosevi with food. Food increases how much Vosevi is absorbed, which increases its effectiveness.
- Tell your doctor if you take any other medications or supplements, including those purchased from a supermarket or health store. Some medications, such as amiodarone, should not be taken with Vosevi.
Response and Effectiveness
- Vosevi cures HCV in most people depending on their genotype and prior exposure to other antiviral agents.
- Cure rates range from 91% to 100% depending on a person's HCV genotype.
- Trials evaluated how effective Vosevi was in people without cirrhosis or with compensated cirrhosis who had either previously received an NS5A inhibitor, or another type of antiviral tre…
- Vosevi cures HCV in most people depending on their genotype and prior exposure to other antiviral agents.
- Cure rates range from 91% to 100% depending on a person's HCV genotype.
- Trials evaluated how effective Vosevi was in people without cirrhosis or with compensated cirrhosis who had either previously received an NS5A inhibitor, or another type of antiviral treatment. A c...
- When looking at specific genotypes, cure rates in those that had previously received an NS5A inhibitor in a trial called POLARIS 1 were as follows: genotype 1a: 96%, genotype 1b: 100%, genotype 2:1...
Interactions
- Medicines that interact with Vosevi may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with Vosevi. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be mana…
References
- Vosevi (sofosbuvir, velpatasvir, and voxilaprevir) [Package Insert]. Updated 10/2021. Gilead Sciences, Inc. https://www.drugs.com/pro/vosevi.html
Further Information
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Vosevi only for the indication prescribed. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Copyright 1996-2022 Drugs.com. Revision date: February 24, 2022. Medical Disc…