How to enroll a patient in Xtandi support solutions?
After the patient has been prescribed XTANDI (enzalutamide), the patient can be enrolled in XTANDI Support Solutions. a Log into Astellas eService b to complete the patient enrollment form. Print to obtain all healthcare provider and patient signatures and then upload through eService or fax to 1-855-982-6341 OR
What is the Xtandi patient savings program?
The XTANDI Patient Savings Program helps eligible patients understand the savings opportunities for XTANDI through their commercial insurance. See below for more details XTANDI Patient Connect helps connect patients and their caregivers to independent resources and services that may help them manage their disease and daily life while on treatment.
What should I avoid while taking Xtandi?
If you take XTANDI, you may be at risk of having a seizure. Avoid activities where a sudden loss of consciousness could seriously harm you or someone else. Tell your doctor right away if you lose consciousness or have a seizure. Posterior Reversible Encephalopathy Syndrome (PRES).
How to get XTANDI for free?
The Astellas Patient Assistance Program provides XTANDI at no cost to patients who meet the program eligibility requirements. All patients in this program who qualify receive their XTANDI prescription at no cost. Call 1-855-8XTANDI (1-855-898-2634) to see if you qualify.
Who is the manufacturer of XTANDI?
XTANDI® is a registered trademark of Astellas Pharma Inc.
What is the monthly cost of XTANDI?
Xtandi Coupon & Prices - Cost $49 per month.
How long does Xtandi extend life?
How long does Xtandi extend life? In the AFFIRM trial, treatment with Xtandi extended life by almost 5 months. Treatment with Xtandi resulted in a median overall survival time of 18.4 months (95% CI 17.3 to not yet reached) compared with 13.6 months (95% CI 11.3 to 15.8) in the placebo recipients (p<0.001).
Does Medicare cover the drug Xtandi?
Do Medicare prescription drug plans cover Xtandi? Yes. 100% of Medicare prescription drug plans cover this drug.
Why does Xtandi cost so much?
But the Xtandi costs are particularly galling because the drug's research and development were underwritten by American taxpayers,” according to their letter. The high cost of the drug means that insurers often require its pre-approval, at repeated intervals, which can delay treatment, the petition's supporters say.
Can Xtandi cause memory loss?
Other side effects include: lower respiratory tract infection, pneumonia, pulmonary infection, altered mental status, amnesia, bronchitis, cognitive dysfunction, falling, hypertension, hypoesthesia, and memory impairment.
Is there a generic version of Xtandi?
Enzalutamide is the generic name for the trade name drug Xtandi®. In some cases, health care professionals may use the trade name Xtandi® when referring to the generic drug name enzalutamide.
Is there a generic for Xtandi?
Enzalutamide is the generic name for the trade name drug Xtandi®. In some cases, health care professionals may use the trade name Xtandi® when referring to the generic drug name enzalutamide.
What happens when you stop taking Xtandi?
If your doctor thinks Xtandi has stopped working they will advise you to stop taking it. In about 50 percent of the men whose PSA level starts to rise again while on antiandrogen therapy, stopping treatment will lead to antiandrogen withdrawal syndrome or antiandrogen withdrawal response (AAWR).
What are the lab abnormalities in Xtandi?
Lab Abnormalities: Lab abnormalities that occurred in ≥ 5% of patients, and more frequently ( > 2%) in the XTANDI arm compared to placebo in the pooled, randomized, placebo-controlled studies are neutrophil count decreased, white blood cell decreased, hyperglycemia, hypermagnesemia, hyponatremia, and hypercalcemia.
What are the most common ARs in Xtandi?
In the data from the four randomized placebo-controlled trials, the most common ARs ( ≥ 10%) that occurred more frequently ( ≥ 2% over placebo) in XTANDI-treated patients were asthenia/fatigue, back pain, hot flush, constipation, arthralgia, decreased appetite, diarrhea, and hypertension. In the bicalutamide-controlled study, the most common ARs ( ≥ 10%) reported in XTANDI-treated patients were asthenia/fatigue, back pain, musculoskeletal pain, hot flush, hypertension, nausea, constipation, diarrhea, upper respiratory tract infection, and weight loss.
Does Xtandi cause seizures?
In a study of patients with predisposing factors for seizure, 2.2% of XTANDI-treated patients experienced a seizure. It is unknown whether anti-epileptic medications will prevent seizures with XTANDI. Patients in the study had one or more of the following predisposing factors: use of medications that may lower the seizure threshold, history of traumatic brain or head injury, history of cerebrovascular accident or transient ischemic attack, and Alzheimer’s disease, meningioma, or leptomeningeal disease from prostate cancer, unexplained loss of consciousness within the last 12 months, history of seizure, presence of a space occupying lesion of the brain, history of arteriovenous malformation, or history of brain infection. Advise patients of the risk of developing a seizure while taking XTANDI and of engaging in any activity where sudden loss of consciousness could cause serious harm to themselves or others. Permanently discontinue XTANDI in patients who develop a seizure during treatment.
Does Xtandi affect other drugs?
Effect of XTANDI on Other Drugs Avoid CYP3A4, CYP2C9, and CYP2C19 substrates with a narrow therapeutic index , as XTANDI may decrease the plasma exposures of these drugs. If XTANDI is co-administered with warfarin (CYP2C9 substrate), conduct additional INR monitoring.
Is Xtandi safe for women?
Embryo-Fetal Toxicity The safety and efficacy of XTANDI have not been established in females. XTANDI can cause fetal harm and loss of pregnancy when administered to a pregnant female. Advise males with female partners of reproductive potential to use effective contraception during treatment with XTANDI and for 3 months after the last dose of XTANDI.
Can Xtandi be taken with other drugs?
Effect of Other Drugs on XTANDI Avoid strong CYP2C8 inhibitors, as they can increase the plasma exposure to XTANDI. If co-administration is necessary, reduce the dose of XTANDI.
