Patient Assistance Programs for Ambrisentan. Patient assistance programs (PAPs) are usually sponsored by pharmaceutical companies and provide free or discounted medicines to low income or uninsured and under-insured people who meet specific guidelines. Eligibility requirements vary for each program. There are currently no Patient Assistance Programs that we know about for this drug.
Full Answer
What type of drug is ambrisentan?
Ambrisentan is an oral medication classified as an endothelin receptor antagonist (ERA) which is approved for the treatment of pulmonary arterial hypertension (PAH) in World Health Organization (WHO) Group 1 patients.
What is the ambrisentan REMS program?
The Ambrisentan REMS is a safety program that manages the risk of serious birth defects when taking ambrisentan. The Ambrisentan REMS is required by the Food and Drug Administration (FDA). Only prescribers and pharmacies certified by the Ambrisentan REMS can prescribe and dispense ambrisentan to patients.
Can ambrisentan be purchased at a local pharmacy?
Ambrisentan is a limited distribution medication, which means it cannot be purchased at a local pharmacy. It must be prescribed by a physician through the Letairis® Education and Access Program (LEAP) and insurance approval must be obtained prior to starting therapy. LEAP will forward the request to a specialty pharmacy.
What are the treatment options for ambrisentan?
Surgical treatment to prevent pregnancy, such as a tubal ligation, is an option. Another contraception option is for women to use a Copper T380A or LNg 20 intrauterine device (IUD). In addition, a pregnancy test prior to the initiation of ambrisentan and monthly thereafter is advised.
What is ambrisentan used for?
Ambrisentan is used alone or in combination with tadalafil (Adcirca, Cialis) to treat pulmonary arterial hypertension (PAH, high blood pressure in the vessels that carry blood to the lungs). Ambrisentan may improve the ability to exercise and slow the worsening of symptoms in people with PAH.
How long does it take for ambrisentan to work?
How long does it take for ambrisentan (Letairis) to work? Most people will start to notice better exercise ability after taking ambrisentan (Letairis) for one month. It can take up to three months to notice the full effects of this medication.
Is ambrisentan FDA approved?
The US Food and Drug Administration (FDA) has approved four generic versions of Gilead Sciences' Letairis (ambrisentan), an endothelin receptor antagonist indicated for treatment for pulmonary arterial hypertension (PAH).
Is ambrisentan the same as Letairis?
Letairis (ambrisentan) is a prescription medicine used to treat pulmonary arterial hypertension (PAH), which is high blood pressure in the arteries of the lungs.
Does ambrisentan lower BP?
What Is Letairis? Letairis (ambrisentan) is an endothelin receptor antagonist used to treat pulmonary arterial hypertension (PAH). Letairis blocks the effects of endothelin-1, helping to decrease the blood pressure in the lungs, slow the worsening of symptoms, and improve your ability to exercise.
Is there a generic for ambrisentan?
On April 11, 2019, Sun launched an AB-rated generic version of Gilead Sciences' Letairis (ambrisentan) tablets. — Mylan, Teva, Zydus, Par, and Sigmapharm received FDA approval of AB-rated generic versions of Letairis.
Who is the manufacturer of ambrisentan?
Ambrisentan is a potent selective endothelin A receptor antagonist, developed by Gilead Sciences and GlaxoSmithKline, for the treatment of pulmonary arterial hypertension (PAH) and idiopathic pulmonary fibrosis.
What is the brand name of tadalafil?
you should know that tadalafil is available under the brand names Adcirca and Cialis. You should only be treated with one of these products at a time. tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take.
What is the brand name for bosentan?
Bosentan, sold under the brand name Tracleer and Safebo among others, is a dual endothelin receptor antagonist medication used in the treatment of pulmonary artery hypertension (PAH). Bosentan is available as film-coated tablets (62.5 mg or 125 mg) or as dispersable tablets for oral suspension (32 mg).
How much does Letairis cost per month?
Letairis Coupon & Prices - Cost $49 per month.
Does ambrisentan cause anemia?
Results from the VOLT post-marketing program confirmed the safety profile of ambrisentan observed in the ARIES studies, including the low incidence of liver function test abnormalities. Peripheral edema and anemia were common side effects of endothelin receptor antagonist therapies, including ambrisentan.
How do you get Letairis?
Ready to get started on Letairis?Letairis is only available through a Certified Pharmacy and will be shipped directly to you. ... Your Certified Pharmacy will call you to coordinate your prescription. ... Sign for delivery when Letairis is shipped to your home.
What are the side effects of ambrisentan?
Incidence not knownChest pain.clay colored stools.decrease in the amount of urine.decreased appetite.dilated neck veins.extreme tiredness or weakness.irregular breathing.large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals.More items...•
Can you crush ambrisentan?
Swallow the tablet whole. Do not crush, break, or chew it. You may take this medicine with or without food.
What is another name for ambrisentan?
Ambrisentan (U.S. trade name Letairis; E.U. trade name Volibris; India trade name Pulmonext by MSN labs) is a drug indicated for use in the treatment of pulmonary hypertension. The peptide endothelin constricts muscles in blood vessels, increasing blood pressure.
What is tadalafil 20 mg used for?
Tadalafil is a medicine used to treat erection problems (erectile dysfunction) and symptoms of an enlarged prostate (benign prostate enlargement). It's also sometimes used to treat pulmonary hypertension (high blood pressure in the blood vessels that supply the lungs). Tadalafil is available on prescription only.
How much does Ambrisentan cost?
The cost for ambrisentan oral tablet 5 mg is around $2,456 for a supply of 10 tablets, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
What is the drug class of Ambrisentan?
Ambrisentan is a member of the agents for pulmonary hypertension drug class and is commonly used for Pulmonary Hypertension.
What is the medication for pulmonary arterial hypertension?
Letairis (ambrisentan) is a prescription medicine used to treat pulmonary arterial hypertension (PAH), which is high blood pressure in the arteries of the lungs.
What are the other possible side effects of Letairis?
Tell your doctor right away if you have any unusual weight gain, tiredness, or trouble breathing while taking Letairis. These may be symptoms of a serious health problem. You may need to be treated with medicine or need to go to the hospital
What should I tell my doctor before taking Letairis?
All your medical conditions. Be sure to tell your doctor if you have a low red blood cell level (anemia) or liver problems
Who should not take Letairis?
You are pregnant, plan to become pregnant, or become pregnant while taking Letairis. Letairis can cause serious birth defects. (See "What is the most important information I should know about Letairis?")
What is Letairis used for?
Letairis is indicated for the treatment of pulmonary arterial hypertension (PAH) (WHO Group 1) in combination with tadalafil to reduce the risks of disease progression and hospitalization for worsening PAH, and to improve exercise ability.
What are the adverse reactions to tadalafil?
Most common adverse reactions in combination with tadalafil compared to Letairis or tadalafil monotherapy were peripheral edema (45% vs 38% or 28%), headache (41% vs 34% or 35%), nasal congestion (19% vs 16% or 11%), cough (18% vs 13% or 16%), anemia (15% vs 7% or 11%), dyspepsia (11% vs 3% or 12%), and bronchitis (10% vs 4% or 9%)
Do female patients have to enroll in Letairis?
All female patients , regardless of reproductive potential, must enroll in the Letairis REMS Program
Does ambrisentan affect sperm count?
Decreased sperm counts have been observed in patients taking endothelin receptor antagonists and in animal fertility studies with ambrisentan. Counsel patients about potential effects on fertility
Is Letairis safe for hepatic impairment?
Hepatic impairment: Letairis is not recommended in patients with moderate or severe hepatic impairment. Fully investigate cause of liver injury in patients who develop hepatic impairment; discontinue Letairis if liver aminotransferases are >5x ULN or if elevations are accompanied by bilirubin >2x ULN, or by signs or symptoms of liver dysfunction and other causes are excluded
What are the side effects of a syringe?
The most common side effects may include swelling of hands, legs, ankles, and feet (peripheral edema), stuffy nose, inflamed nasal passages, hot flashes or getting red in the face (flushing).
Who is Prescription Hope?
Prescription Hope is a nationally recognized prescription medication access program, headquartered in Columbus, Ohio. Prescription Hope offers access to over 1,500 brand-name medications through patient assistance programs. All you pay is a set service fee of $50 for each medication per month. This includes 100% of the medication cost, no matter the retail price.
Can Prescription Hope Get My Letairis If I Have Health Insurance Coverage?
Because Prescription Hope is not a health insurance plan, our program works alongside any coverage you may currently have to obtain your Letairis medication at an affordable price. Our national advocacy program does not have medication tiers, copays, or deductibles.
What is Letairis used for?
Letairis is used to treat pulmonary arterial hypertension and may also help make exercise and breathing easier.
How to get more information about Letairis?
To receive farther information about Letairis and its effects, talk to your doctor.
Do I Qualify For Letairis Patient Assistance With Prescription Hope?
Prescription Hope works with thousands of Americans every month, obtaining prescription medications on their behalf for the set price of $50.00 per month per medication.
How much does Letairis cost?
Patients who have commercial insurance may pay as little as $5 per month for Letairis. Eligible patients are automatically enrolled when they are prescribed branded Letairis.
What are the other possible side effects of Letairis?
Tell your doctor right away if you have any unusual weight gain, tiredness, or trouble breathing while taking Letairis. These may be symptoms of a serious health problem. You may need to be treated with medicine or need to go to the hospital
Who should not take Letairis?
You are pregnant, plan to become pregnant, or become pregnant while taking Letairis. Letairis can cause serious birth defects. (See "What is the most important information I should know about Letairis?")
What to do if you don't have insurance for Letairis?
If you are uninsured or underinsured. If you do not have insurance or your insurance does not cover Letairis costs, LEAP can offer guidance and may be able to help identify financial support for Letairis.
What is the medication for pulmonary arterial hypertension?
Letairis (ambrisentan) is a prescription medicine used to treat pulmonary arterial hypertension (PAH), which is high blood pressure in the arteries of the lungs. How LEAP Can HelpFinancial Resources. Stay on track with supportSupport from LEAP is only available with . branded Letairis.
What should I tell my doctor before taking Letairis?
All your medical conditions. Be sure to tell your doctor if you have a low red blood cell level (anemia) or liver problems
Who should not take Letairis?
You are pregnant, plan to become pregnant, or become pregnant while taking Letairis. Letairis can cause serious birth defects. (See "What is the most important information I should know about Letairis?")
How long does it take for a fluid to reappear after taking Letairis?
Swelling all over the body (fluid retention) can happen within weeks after starting Letairis. Tell your doctor right away if you have any unusual weight gain, tiredness, or trouble breathing while taking Letairis. These may be symptoms of a serious health problem. You may need to be treated with medicine or need to go to the hospital
Does Letairis help with physical symptoms?
Letairis can improve your ability to exercise and it can help slow down the worsening of your physical condition and symptoms
Does Letairis cause swelling?
The most common side effects of Letairis are swelling of hands, legs, ankles and feet (peripheral edema), stuffy nose (nasal congestion), inflamed nasal passages (sinusitis), hot flashes or getting red in the face (flushing). Tell your doctor if you have any side effect that bothers you or does not go away.
What is the number to call for Letairis?
If your patients are struggling to cover out-of-pocket costs or have no insurance at all, encourage them to call 1-866-664-5327 to explore possible support options. Learn more about how LEAP can help. Start a patient on Letairis. Review clinical results.
What is Letairis used for?
Letairis is indicated for the treatment of pulmonary arterial hypertension (PAH) (WHO Group 1) in combination with tadalafil to reduce the risks of disease progression and hospitalization for worsening PAH, and to improve exercise ability.
What are the adverse reactions to tadalafil?
Most common adverse reactions in combination with tadalafil compared to Letairis or tadalafil monotherapy were peripheral edema (45% vs 38% or 28%), headache (41% vs 34% or 35%), nasal congestion (19% vs 16% or 11%), cough (18% vs 13% or 16%), anemia (15% vs 7% or 11%), dyspepsia (11% vs 3% or 12%), and bronchitis (10% vs 4% or 9%)
Does ambrisentan affect sperm count?
Decreased sperm counts have been observed in patients taking endothelin receptor antagonists and in animal fertility studies with ambrisentan. Counsel patients about potential effects on fertility
Is Letairis safe for hepatic impairment?
Hepatic impairment: Letairis is not recommended in patients with moderate or severe hepatic impairment. Fully investigate cause of liver injury in patients who develop hepatic impairment; discontinue Letairis if liver aminotransferases are >5x ULN or if elevations are accompanied by bilirubin >2x ULN, or by signs or symptoms of liver dysfunction and other causes are excluded
