Full Answer
What is the Endari copay assistance program?
A copay assistance program is available for eligible patients covered under commercial or private insurance who require assistance with out-of-pocket costs associated with their ENDARI prescription. Patients with coverage from a federally funded program (such as Medicare or Medicaid) are not eligible for the copay assistance program.
What is Endari?
The first treatment for sickle cell disease in nearly 20 years. Available for adults and children 5 years and older to reduce the acute complications of sickle cell disease. ENDARI is indicated to reduce the acute complications of sickle cell disease in adults and children 5 years of age and older.
How do I get a copy of my Endari offer?
Some offers may be printed right from a website, others require registration, completing a questionnaire, or obtaining a sample from the doctor's office. Endari Commercial Copayment Assistance Program: Eligible commercially insured patients pay a $10 monthly copay; for additional information contact the program at 855-723-5646.
Who is required to pay the first co-payment for Endari?
Patient is required to pay the first $10.00 of their monthly co-payment for ENDARI. Emmaus reserves the right to terminate, rescind, revoke, or modify this Program at any time without notice. ENDARI is indicated to reduce the acute complications of sickle cell disease in adults and children 5 years of age and older.
What company makes Endari?
About Emmaus Life Sciences, Inc. Its lead product, Endari, demonstrated positive clinical results in the completed Phase 3 clinical trial for sickle cell anemia and sickle ß0-thalassemia and has received FDA approval.
Is Endari a specialty drug?
ENDARI is a specialty medication and may not be available at your usual pharmacy. Your physician will typically send your prescription to a specialty pharmacy that will fill your ENDARI prescription.
How do you take Endari?
Take your prescribed dose of ENDARI twice a day – once in the morning and once in the evening. Each packet of ENDARI is 5 grams. Fill a cup or bowl with 4 to 6 ounces of food like yogurt or applesauce. DO NOT USE A HOT FOOD.
What drug class is Endari?
Endari (L-glutamine oral powder) is an amino acid indicated to reduce the acute complications of sickle cell disease in adult and pediatric patients 5 years of age and older.
How does hydroxyurea treat sickle cell?
Hydroxyurea makes your red blood cells bigger. It helps them stay rounder and more flexible — and makes them less likely to turn into a sickle shape. The medicine does this by increasing a special kind of hemoglobin called hemoglobin F.
What is the side effects of glutamine?
Side EffectsBlood in urine.changes in skin color.cold hands and feet.difficulty swallowing.fast heartbeat.frequent and painful urination.hives, itching, skin rash.lightheadedness.More items...•
Does sickle cell get worse with age?
Because SCD is a genetic disease, people must be born with it. Children begin showing symptoms around 5 months old. Symptoms and complications then tend to get worse with age. The transition from pediatric to adult care is also linked to more medical problems.
What vitamins are good for sickle cell?
Supplementing with vitamin C may help correct a deficiency. Antioxidant nutrients protect the body's cells from oxygen-related damage. Many studies show that sickle cell anemia patients tend to have low blood levels of antioxidants, including carotenoids, vitamin A, vitamin E, and vitamin C, despite adequate intake.
Is Endari FDA approved?
Endari® was approved by the FDA in July 2017 for the treatment of sickle cell disease in adult and pediatric patients five years of age and older and sales began in 2018.
Is L-glutamine FDA approved?
On July 7, 2017, the U.S. Food and Drug Administration approved L-glutamine oral powder (Endari, Emmaus Medical, Inc.) for oral administration to reduce the acute complications of sickle cell disease in adult and pediatric patients 5 years and older.
Is Crizanlizumab FDA approved?
FDA Approves ADAKVEO (Crizanlizumab-tmca) to Reduce the Frequency of Vasoocclusive Crises in Adults and Pediatric Patients Aged 16 Years and Older with Sickle Cell Disease.
How does L-glutamine help sickle cell?
L-glutamine is a naturally occurring amino acid. Although the mechanism of action for L-glutamine is not fully understood, its use in sickle cell disease is based on its antioxidant activity. It increases NAD redox potential in sickle red blood cells through increasing the availability of reduced glutathione.
What age is Endari recommended for?
ENDARI is indicated to reduce the acute complications of sickle cell disease in adults and children 5 years of age and older.
Is Endari safe for children?
It is not known whether ENDARI is safe and effective in children with sickle cell disease young er than 5 years old. Talk to your doctor to determine if prescription ENDARI is right for you. You may report side effects to the FDA. Visit www.fda.gov/MedWatch or call 1-800-FDA-1088.
INDICATION
ENDARI is indicated to reduce the acute complications of sickle cell disease in adults and children 5 years of age and older.
IMPORTANT SAFETY INFORMATION
The most common side effects in clinical studies were constipation, nausea, headache, pain in the stomach area, cough, pain in hands or feet, back pain, and chest pain.
What is endari used for?
Endari (glutamine) is a member of the nutraceutical products drug class and is commonly used for Anemia - Sickle Cell.
Is Endari a generic?
Endari is available as a brand name drug only, a generic version is not yet available. For more information, read about generic Endari availability . This Endari price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
INDICATION
ENDARI is indicated to reduce the acute complications of sickle cell disease in adults and children 5 years of age and older.
IMPORTANT SAFETY INFORMATION
The most common side effects in clinical studies were constipation, nausea, headache, pain in the stomach area, cough, pain in hands or feet, back pain, and chest pain.
What is Endari for kids?
About ENDARI. ENDARI is a medication to reduce the acute complications of sickle cell disease in adults and children 5 years and older. ENDARI is pharmaceutical grade l-glutamine oral powder that has been shown to reduce the acute complications of sickle cell disease in adults and children 5 years and older when taken as directed.
How to report Endari side effects?
You may report side effects to the FDA. Visit www.fda.gov/MedWatch or call 1-800-FDA-1088. You can also call Emmaus Medical, Inc. at 1-855-725-0900. For more information, please read the full Prescribing Information, including Instructions for Use, for ENDARI.
How many sachets of Endari powder are in a carton?
ENDARI comes in a carton that holds 60 individually packaged sachets of ENDARI powder.
What age is Endari recommended for?
ENDARI is indicated to reduce the acute complications of sickle cell disease in adults and children 5 years of age and older.
Is Endari safe for kids?
Side effects that lead to a stop in treatment during the clinical study were, one case each of overactive spleen (an organ that helps filter your blood), pain in the stomach area, indigestion, burning sensation, and hot flash. It is not known whether ENDARI is safe and effective in children with sickle cell disease younger than 5 years old .
