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imatinib patient assistance

by Prof. Eula Abernathy Published 1 year ago Updated 1 year ago
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 The Sun Pharma Imatinib Patient Assistance Program is offered to allow qualified patients to obtain free medication. It is not a government program or an insurance plan.  If a patient qualifies, they may receive free Imatinib medication each month through July 2016 as long as they continue to meet the program requirements.

Full Answer

What is imatinib?

It is used to treat certain leukemias, myelodysplastic syndromes, and other cancers. It is also used to treat specific digestive tract tumors called GISTs. The lowest GoodRx price for the most common version of imatinib is around $114.15, 97% off the average retail price of $4,734.14.

How much does imatinib cost without insurance?

The cost for imatinib oral tablet 100 mg is around $86 for a supply of 90 tablets, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans. Important: When there is a range of pricing, consumers should normally expect to pay the lower price.

How much chlordiazepoxide should I take to help with imatinib?

In one report, 10 mg at bedtime of chlordiazepoxide (which has sedative, anxiety-reducing, and muscle relaxant properties) helped one patient according to Medeiros and Lipton, 2006 ). Patients newly prescribed imatinib receive blood tests (more frequent early in therapy) to identify any liver function or blood count abnormalities.

Does imatinib cause reduced heart fungus?

A new paper by Kerkela et al (2006) suggests that a small percent of patients taking imatinib may experience reduced heart funct ion. Dr. Thomas Force, the corresponding author of the paper, discussed this possibility on National Public Radio on July 28, 2006. Dr. Force also spoke by phone to GSI.

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How do people afford Gleevec?

Novartis Oncology Universal Co-pay Program – To understand your out-of-pocket costs for Gleevec and to see if you are eligible to pay $10 for a 30-day supply with the Gleevec $10 Co-Pay Card, call 1-866-GLEEVEC (1-866-453-3832) or visit enroll in the Novartis Oncology Universal Co-pay Program.

What is the income requirements for Novartis patient assistance?

To be eligible for NPAF assistance, you must:Household SizeAnnual Household Income Threshold2 People< USD 100 0003 People< USD 125 0004 People< USD 150 000> 5 PeopleAdd USD 25 000 for each additional person1 more row

How do you deal with imatinib?

You have imatinib as a tablet that you swallow whole, with a glass of water after food. If you can't swallow the tablets, you can dissolve them in a glass of mineral water or apple juice. Drop the whole tablets into the fluid, and stir with a spoon until the tablets have broken up completely.

How can I reduce the side effects of imatinib?

Imatinib sometimes causes side effects due to the rapid destruction of cancer cells (tumor lysis syndrome). To lower your risk, drink plenty of fluids unless your doctor directs you otherwise. Also, your doctor may prescribe an additional medication.

What is Novartis program?

If you have limited or no insurance coverage, the Novartis Patient Assistance Foundation, Inc. provides medicines at no cost to eligible US patients who are experiencing financial hardship.

How do you qualify for free eliquis?

You may be eligible for the Free 30-Day Trial Offer for ELIQUIS® (apixaban) if:You have not previously filled a prescription for ELIQUIS;You have a valid 30-day prescription for ELIQUIS;You are being treated with ELIQUIS for an FDA-approved indication that an HCP has planned for more than 35 days of treatment;More items...

How long can you stay on imatinib?

Optimal duration of therapy is unknown but generally imatinib should be continued for 6–9 months, after which additional tumor shrinkage is usually minor.

Does imatinib affect sleep?

Until recently, imatinib and related drugs for CML, known as tyrosine kinase inhibitors (TKIs), had to be taken every day for life, and the drugs can cause fatigue, depression, disrupted sleep, diarrhea, and other side effects.

Does imatinib make tired?

One of the main side effects of long-term treatment with imatinib is chronic tiredness, also known as fatigue. But fatigue is more than just being tired. It is more a feeling of lassitude, getting tired fast and feeling less efficient.

Does imatinib cause weight gain?

The median weight at the start of imatinib therapy was 76.8 kg (range 49.7-123). There was a statistically significant gain in weight in evaluable patients even at 6 months (P < . 0001), with more than 75% of patients gaining weight (Tables 1 and 2).

Can I drink coffee while taking Gleevec?

during Gleevec use may want to avoid certain foods and beverages (i.e., spicy foods, chocolate, caffeine, citrus juice, dairy products, etc.) that may exacerbate these unwanted effects.

Does imatinib cause hair loss?

In most cases, the drug is well tolerated: however, side effects can be seen. Hair loss and paronychia inflammation were often reported with Imatinib, but total alopecia was rarely mentioned. We report a CML patient who was presented with alopecia and paronychia inflammation probably induced by imatinib therapy.

How do I get Cosentyx for free?

If you have commercial or private insurance and your prescription coverage isn't initially approved, you may get up to 2 years of COSENTYX for free through Covered Until You're Covered while we work with your healthcare provider to try to secure coverage for COSENTYX.

Does reclast have a copay card?

Reclast Coupons, Copay Cards and Rebates Reclast offers may be in the form of a printable coupon, rebate, savings or copay card, trial offer, or free samples. Some offers may be printed right from a website, others require registration, completing a questionnaire, or obtaining a sample from the doctor's office.

How does Xolair co-pay assistance work?

Your doctor's office, AIC, HOPD or specialty pharmacy† will use your account to pay part of your out-of-pocket cost. You will pay the first $5 for your drug out-of-pocket cost and/or the first $5 for your injection out-of-pocket cost. *EOBs must be submitted within 365 days of the date of service.

How does Entresto copay card work?

Eligible commercially insured patients get each 30-, 60-, or 90-day supply of Entresto® for as little as a $10 co-pay. The program pays the balance of the co-pay per fill, up to a total maximum of $2500 per calendar year. Offer not valid under Medicare, Medicaid, or any other federal or state program.

What is imatinib used for?

Imatinib is a member of the BCR-ABL tyrosine kinase inhibitors drug class and is commonly used for Acute Lymphoblastic Leukemia, Chronic Eosinophilic Leukemia, Chronic Myelogenous Leukemia, and others.

How much does imatinib cost?

Imatinib Prices. The cost for imatinib oral tablet 400 mg is around $102 for a supply of 30 tablets, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.

How much does a free drug card save?

The free Drugs.com Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions.

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

Uses

Imatinib is used to treat a type of leukemia (chronic myeloid leukemia or CML) as well as certain intestinal tumors (GISTs).

How To Use

Take this medication by mouth with a meal and a large glass of water, usually once or twice daily; or take as directed by your doctor. If you have trouble swallowing the tablets whole, you may dissolve your dose in a glass of water or apple juice.

Side Effects

Nausea, vomiting, diarrhea, swelling (especially in the legs or around the eyes), or muscle cramps may occur. If any of these effects persist or worsen, notify your doctor. Tell your doctor immediately if any of these serious side effects occur: joint/muscle pain, stomach pain, severe weakness.

Precautions

Tell your doctor your medical history, especially of: liver problems, kidney problems, heart disease, lung disease (e.g., asthma, COPD), other cancer or blood disorders, any allergies.

Drug Interactions

Tell your doctor of all prescription and nonprescription medication you may use, especially of: other cancer drugs (e.g., tamoxifen), drugs used for HIV (e.g., efavirenz, indinavir, nevirapine, ritonavir), cimetidine, "blood thinners" (e.g., warfarin), azole antifungals (e.g., itraconazole, ketoconazole), macrolide antibiotics (e.g., clarithromycin, erythromycin), anti-seizure medications (e.g., carbamazepine, phenobarbital, phenytoin), corticosteroids (e.g., prednisone), cholesterol-lowering drugs (e.g., "statins" such as atorvastatin, lovastatin), cyclosporine, tacrolimus, cisapride, calcium channel blockers (e.g., diltiazem, verapamil), heart rhythm drugs (e.g., amiodarone, quinidine), certain diabetes medications (e.g., glipizide, pioglitazone, troglitazone), rifampin, St.

Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include: yellowing eyes and skin, dark urine, change in amount of urine (severe increase or decrease).

How should I take my imatinib?

The Novartis prescribing information advises taking imatinib with food and a large glass of water. Because the half-life is about 18 hours, it is possible to take the entire daily dose at once for doses up to 600 mg, but Novartis advises splitting higher doses. Many patients prefer to split lower doses because this may minimize side effects, and it is acceptable to split any daily dose, as confirmed by Novartis in an opinion shown on our page Novartis Answers ABout Gleevec.

Where can I see detailed information about imatinib effectiveness?

You can view webcasts from the American Society of Clinical Oncology and other medical association meetings to hear presentations and see the slides used by presenters in discussing the research done on imatinib (Gleevec) used against GIST. Direct links to most of the available presentations are provided for you on our page Webcasts and Slide Shows . You can also obtain the medical papers and presentations identified with links earlier in this page.

How does imatinib work?

Focusing on GIST, the effect of imatinib (Gleevec) is to stop the cell-proliferation actions of the KIT and PDGFRA tyrosine kinases. These are growth factor receptors that initiate a signaling pathway causing the cell to proliferate (reproduce through cell division). When GIST cells divide, the tumor gets larger. This signaling normally occurs only when KIT or PDGFRA receptors are triggered by molecules called ligands. The ligand for KIT is stem cell factor, and the ligand for PDGFRA is platelet-derived growth factor (PDGF). However, when the genes for these receptors are mutated, then the proteins are abnormally constructed, and they activate signaling without being stimulated by their ligands (constitutive activation). This abnormal growth signaling causes the GI stromal tumor to develop and keep enlarging. You can refer to our website page Mutation Analysis: KIT and PDGFRA for a more detailed discussion. Imatinib binds the intracellular activation pocket of the receptor in the inactive position, blocking binding by ATP, and thereby preventing the growth signals from being sent.

What are the side effects of imatinib?

The percent of subjects showing less severe side effects (grades 1 and 2) versus more severe side effects (grades 3 and 4) are shown separately for the groups assigned to take 400 mg imatinib per day versus 800 mg imatinib per day .

What drug interactions occur with imatinib?

Imatinib (Gleevec) is metabolized primarily by liver enzyme CYP3A4. Therefore, drugs also metabolized by this same enzyme may interact with imatinib, as well as drugs or other substances that increase (induce) or decrease (inhibit) the amount of this enzyme in the body. Information about drug interactions is available in the prescribing information for imatinib at the website http://www.gleevec.com/ and in Griffin, St. Amand and Demetri (2005). Patients already taking other medications can consult their pharmacists for an analysis of any potential interactions.

What about pregnancy and imatinib?

Patients and their partners are advised to use birth control while either the man or the woman is taking imatinib (Gleevec) and for 3 months after stopping imatinib. For data on pregnancy outcomes of patients on Gleevec, see Pregnancy and Gleevec.

How long does it take for imatinib to show side effects?

The finding for increased side effects at higher doses has held true across all the available imatinib trials. Most side effects appear within the first few months of imatinib therapy. There is general agreement that side effects diminish with time. Additional information about side effects can be found in the complete prescribing information.

What is imatinib used for?from drugs.com

Imatinib is a member of the BCR-ABL tyrosine kinase inhibitors drug class and is commonly used for Acute Lymphoblastic Leukemia, Chronic Eosinophilic Leukemia, Chronic Myelogenous Leukemia, and others.

How much does imatinib cost?from drugs.com

Imatinib Prices. The cost for imatinib oral tablet 400 mg is around $102 for a supply of 30 tablets, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.

Can I obtain other prescription medications through Prescription Hope?from prescriptionhope.com

In addition to Imatinib, Prescription Hope can obtain over 1,500 FDA-approved prescription medications. There is no limit to the number of medications individuals can receive through our pharmacy program.

How long does it take for prescription hope to send medication?from prescriptionhope.com

When your application is approved, the first shipment of medication is typically sent within four to six weeks, with regular refills coming to either your home or doctor’s office.

How to contact prescription hope?from prescriptionhope.com

In the event your additional prescription medications are not currently on our list, contact our advocates at 1-877-296-HOPE (4673) today to see if it has been added.

How much does a free drug card save?from drugs.com

The free Drugs.com Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions.

Can Prescription Hope help me with Imatinib if I have prescription medication coverage?from prescriptionhope.com

Prescription Hope works alongside many prescription medication coverage plans and fill the coverage gap individuals may fall into through insurance and Medicare. Through our unique pharmacy program, Prescription Hope can obtain prescription medications without copays, deductibles or medication tiers.

How much does imatinib cost?from drugs.com

Imatinib Prices. The cost for imatinib oral tablet 400 mg is around $102 for a supply of 30 tablets, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.

What is PAF in Novartis?from hematology.org

The Novartis Patient Assistance Foundation (PAF) can help patients acquire high cost drugs either for free or at reduced process. For help acquiring imatinib, visit the online enrollment page, select imatinib, and fill in the required information.

How much does a free drug card save?from drugs.com

The free Drugs.com Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions.

Does Patient Access Network Foundation offer co-pay assistance?from hematology.org

The Patient Access Network Foundation also offers co-pay assistance for patients needing imatinib. Please read the application instructions , and then follow the prompts on the online application .

How much does imatinib cost?from drugs.com

Imatinib Prices. The cost for imatinib oral tablet 400 mg is around $102 for a supply of 30 tablets, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.

What is PAF in Novartis?from hematology.org

The Novartis Patient Assistance Foundation (PAF) can help patients acquire high cost drugs either for free or at reduced process. For help acquiring imatinib, visit the online enrollment page, select imatinib, and fill in the required information.

How much does a free drug card save?from drugs.com

The free Drugs.com Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions.

Does Patient Access Network Foundation offer co-pay assistance?from hematology.org

The Patient Access Network Foundation also offers co-pay assistance for patients needing imatinib. Please read the application instructions , and then follow the prompts on the online application .

What is billing assistance?

Billing assistance - Discuss any billing questions with reimbursement specialists. Also, if a claim is denied due to billing errors or medical necessity issues, specialists can help patients develop strategies for appeal.

What is a national patient travel center?

National Patient Travel Center Provides information about all forms of charitable, long-distance medical air transportation and provides referrals to all appropriate sources of help available in a national charitable medical air transportation network.

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Important Note

  • The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug. IMATINIB - ORAL (ih-MAT-in-ibb) COMMON BRA…
See more on patientassistance.com

Uses

  • Imatinib is used to treat a type of leukemia (chronic myeloid leukemia or CML) as well as certain intestinal tumors (GISTs).
See more on patientassistance.com

How to Use

  • Take this medication by mouth with a meal and a large glass of water, usually once or twice daily; or take as directed by your doctor. If you have trouble swallowing the tablets whole, you may dissolve your dose in a glass of water or apple juice. The amount of liquid will vary depending on your dose; consult your doctor or pharmacist for more deta...
See more on patientassistance.com

Side Effects

  • Nausea, vomiting, diarrhea, swelling (especially in the legs or around the eyes), or muscle cramps may occur. If any of these effects persist or worsen, notify your doctor. Tell your doctor immediately if any of these serious side effects occur: joint/muscle pain, stomach pain, severe weakness. Tell your doctor immediately if any of these unlikely but serious side effects occur: tr…
See more on patientassistance.com

Precautions

  • Tell your doctor your medical history, especially of: liver problems, kidney problems, heart disease, lung disease (e.g., asthma, COPD), other cancer or blood disorders, any allergies. Because this medication and/or your medical condition can lower your body's ability to fight an infection, do not touch your eyes or the inside of your nose without first washing your hands. Do not have immuni…
See more on patientassistance.com

Drug Interactions

  • Tell your doctor of all prescription and nonprescription medication you may use, especially of: other cancer drugs (e.g., tamoxifen), drugs used for HIV (e.g., efavirenz, indinavir, nevirapine, ritonavir), cimetidine, "blood thinners" (e.g., warfarin), azole antifungals (e.g., itraconazole, ketoconazole), macrolide antibiotics (e.g., clarithromycin, erythromycin), anti-seizure medication…
See more on patientassistance.com

Overdose

  • If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include: yellowing eyes and skin, dark urine, change in amount of urine (severe increase or decrease).
See more on patientassistance.com

Notes

  • Do not share this medication with others. Laboratory and/or medical tests (e.g., blood tests, liver function tests) will be performed to monitor your progress.
See more on patientassistance.com

Missed Dose

  • If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
See more on patientassistance.com

Storage

  • Store at controlled room temperature (77 degrees F or 25 degrees C) away from light and moisture. Brief storage between 59 and 86 degrees F (15 to 30 degrees C) is permitted.
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