Patient Assistance & Copay Programs for Soliris Patient assistance programs (PAPs) are usually sponsored by pharmaceutical companies and provide free or discounted medicines and copay programs to low income or uninsured and under-insured people who meet specific guidelines. Eligibility requirements vary for each program.
Full Answer
What is Soliris used to treat?
Soliris Prices, Coupons and Patient Assistance Programs. Soliris (eculizumab) is a member of the selective immunosuppressants drug class and is commonly used for Hemolytic Uremic Syndrome, Myasthenia Gravis and Paroxysmal Nocturnal Hemoglobinuria.
Is Soliris safe for children with NMOSD?
SOLIRIS ® (eculizumab) is an FDA-approved prescription medicine used to treat adults with neuromyelitis optica spectrum disorder (NMOSD) who are anti-aquaporin-4 (AQP4) antibody positive. It is not known if SOLIRIS is safe and effective in children with NMOSD.
How do I enroll in the Soliris REMS program?
Under the Soliris REMS, prescribers must enroll in the program. Enrollment in the Soliris REMS program and additional information are available by telephone: 1-888-SOLIRIS (1-888-765-4747) or at www.solirisrems.com. The use of Soliris increases a patient’s susceptibility to serious meningococcal infections (septicemia and/or meningitis).
How do I contact Soliris?
Visit MedWatch, or call 1-800-FDA-1088. What is SOLIRIS? SOLIRIS is a prescription medicine used to treat adults with a disease called generalized myasthenia gravis (gMG) who are anti-acetylcholine receptor (AChR) antibody positive.
How much does SOLIRIS cost per year?
Table 8CADTH Cost Comparison Table for Prescription Drugs Indicated for NMOSD PatientsTreatmentStrengthAverage annual drug cost, $Eculizumab (Soliris)10 mg/mLYear 1: 728,136 Thereafter: 701,168
Can SOLIRIS be given at home?
SOLIRIS is a treatment that is given by intravenous (IV) infusion. Some people visit an infusion center to receive SOLIRIS while others prefer to have a visiting nurse administer their infusion at home. The location in which you receive your infusion can depend on your insurance and where you live.
How is SOLIRIS supplied?
DOSAGE FORMS AND STRENGTHS Soliris is supplied as 300 mg single-use vials each containing 30 mL of 10 mg/mL sterile, preservative-free eculizumab solution.
How does SOLIRIS help myasthenia gravis?
Soliris is thought to work in MG by inhibiting the complement pathway to prevent destruction of the neuromuscular junction.
What happens if you stop SOLIRIS?
If you have PNH, your doctor will need to monitor you closely for at least 8 weeks after stopping SOLIRIS. Stopping treatment with SOLIRIS may cause breakdown of your red blood cells due to PNH. treatment for signs of worsening aHUS symptoms or problems related to abnormal clotting (thrombotic microangiopathy).
How long is SOLIRIS treatment?
For adult patients with generalized myasthenia gravis or neuromyelitis optica spectrum disorder, Soliris therapy consists of: 900 mg weekly for the first 4 weeks, followed by. 1200 mg for the fifth dose 1 week later, then. 1200 mg every 2 weeks thereafter.
How long does it take for Soliris to work?
Individuals who respond to eculizumab often see improvement in the first one to two months. However, it may take up to 12 weeks for some people with MG to see improvement.
How often is Soliris administered?
Recommended Dosage Regimen – aHUS For patients 18 years of age and older, Soliris therapy consists of: 900 mg weekly for the first 4 weeks, followed by. 1200 mg for the fifth dose 1 week later, then. 1200 mg every 2 weeks thereafter.
What is the price of eculizumab?
Soliris (eculizumab), for PNH, annual cost: $409,500. Manufacturer: Alexion Pharmaceuticals.
Is Soliris a chemo drug?
Eculizumab is the generic name for the trade chemotherapy drug Soliris. In some cases, health care professionals may use the trade name Soliris when referring to the generic drug name eculizumab. Drug Type: Soliris is a “monoclonal antibody” that binds or attaches to a protein present in the blood.
What is the new myasthenia gravis drug?
Ultomiris (ravulizumab-cwvz) has been approved in the US for the treatment of adult patients with generalised myasthenia gravis (gMG) who are anti-acetylcholine receptor (AChR) antibody-positive, which represents 80% of people living with the disease.
Is there any new medicine for myasthenia gravis?
The U.S. Food and Drug Administration today approved Vyvgart (efgartigimod) for the treatment of generalized myasthenia gravis (gMG) in adults who test positive for the anti-acetylcholine receptor (AChR) antibody.
How is Solaris given?
This medication is given by injection into a vein by a health care professional as directed by your doctor. It is usually given every 7 days for 5 weeks, then every 14 days. The dosage is based on your medical condition. For children, the dosage is also based on the weight.
Is there a generic for Soliris?
Eculizumab is the generic name for the trade chemotherapy drug Soliris. In some cases, health care professionals may use the trade name Soliris when referring to the generic drug name eculizumab.
What is a Soliris infusion?
Soliris is used to prevent the breakdown of red blood cells in adults with paroxysmal nocturnal hemoglobinuria (PNH). Soliris is also used to treat a rare chronic blood disease called atypical hemolytic uremic syndrome (aHUS) in adults and children who weigh at least 11 pounds (5 kilograms).
Is Soliris a monoclonal antibody?
SOLIRIS® (eculizumab) is a monoclonal antibody that specifically binds with high affinity to the complement protein C5, inhibiting its cleavage to C5a and C5b and preventing the generation of the terminal complement complex C5b-9. C5 inhibitors have no impact on antibody production.
How to report side effects of Soliris?
Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit MedWatch, or call 1-800-FDA-1088. Please see the full Prescribing Information and Medication Guide for SOLIRIS, including Boxed WARNING regarding serious and life-threatening meningococcal infections.
How long should you take antibiotics before taking Soliris?
It is important that you have all recommended vaccinations before you start SOLIRIS, receive 2 weeks of antibiotics if you immediately start SOLIRIS, and stay up-to-date with all recommended vaccinations during treatment with SOLIRIS.
How long do you have to carry a patient safety card?
Carry it with you at all times during treatment and for 3 months after your last SOLIRIS dose. It is important to show this card to any doctor or nurse to help them diagnose and treat you quickly.
What is a OneSource case manager?
OneSource Case Managers have anti-AChR Ab+ gMG disease education and health insurance expertise. One will be assigned to you to provide complimentary one-on-one education and support. You may also contact your OneSource Case Manager to request a gMG Treatment Journal to use along your journey.
Can you pass out from a soliris infusion?
SOLIRIS can cause serious side effects including serious infusion-related reactions. Tell your doctor or nurse right away if you get any of these symptoms during your SOLIRIS infusion: chest pain; trouble breathing or shortness of breath; swelling of your face, tongue, or throat; and feel faint or pass out.
Does soliris affect the immune system?
SOLIRIS is a medicine that affects your immune system and can lower the ability of your immune system to fight infections. SOLIRIS increases your chance of getting serious and life-threatening meningococcal infections that may quickly become life-threatening and cause death if not recognized and treated early.
Is Soliris a boxed medicine?
Please see the full Prescribing Information and Medication Guide for SOLIRIS, including Boxed WARNING regarding serious and life-threatening meningococcal infections. SOLIRIS is a medicine that affects your immune system and can lower the ability of your immune system to fight infections.
How to report side effects of Soliris?
These are not all the possible side effects of SOLIRIS. For more information, ask your doctor or pharmacist. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit MedWatch, or call 1-800-FDA-1088.
What is the most important information about Soliris?
What is the most important information I should know about SOLIRIS? SOLIRIS is a medicine that affects your immune system and can lower the ability of your immune system to fight infections.
How long do you have to carry a patient safety card?
Carry it with you at all times during treatment and for 3 months after your last SOLIRIS dose. It is important to show this card to any doctor or nurse to help them diagnose and treat you quickly.
Does Soliris help with NMOSD?
Soliris may be able to help reduce your risk of relapse. Whether you are newly diagnosed or have had multiple relapses, see how it may be able to help you control your NMOSD.
Does Soliris lower the immune system?
SOLIRIS is a medicine that affects your immune system and can lower the ability of your immune system to fight infections.
Does soliris cause gonorrhea?
SOLIRIS may also increase the risk of other types of serious infections. Certain people may be at risk of serious infections with gonorrhea. Certain fungal infections ( Aspergillus) may occur if you take SOLIRIS and have a weak immune system or a low white blood cell count.
Is Soliris a boxed warning?
Please see the accompanying full Prescribing Information and Medication Guide for SOLIRIS, including Boxed WARNING regarding serious and life-threatening meningococcal infections.
What is Soliris used for?
Soliris (eculizumab) is a member of the selective immunosuppressants drug class and is commonly used for Hemolytic Uremic Syndrome, Myasthenia Gravis, Neuromyelitis Optica, and others.
How much does Soliris cost?
The cost for Soliris intravenous solution (10 mg/mL) is around $6,820 for a supply of 30 milliliters, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
How to enroll in Soliris?
Under the Soliris REMS, prescribers must enroll in the program. Enrollment in the Soliris REMS program and additional information are available by telephone: 1-888-SOLIRIS ( 1-888-765-4747) or at www.solirisrems.com.
What is Soliris used for?
Soliris is indicated for the treatment of neuromyelitis optica spectrum disorder (NMOSD) in adult patients who are anti-aquaporin-4 (AQP4) antibody positive.
What is the Alexion OneSource program?
IMPORTANT NOTICE: The Alexion OneSource™ Copay Program (“Program”) pays for eligible out-of-pocket medication and infusion costs associated with SOLIRIS ® (eculizumab) up to $15,000 US dollars per calendar year. The Program is not valid for costs eligible to be reimbursed, in whole or in part, by Medicaid, Medicare (including Medicare Part D), Medicare Advantage Plans, Medigap, Veterans Affairs, Department of Defense or TRICARE, or other federal or state programs (including any state prescription drug assistance programs). No claim for reimbursement of any out-of-pocket expense amount covered by the Program may be submitted to any third-party payer, whether public or private. This offer cannot be combined with any other rebate/coupon, free trial, or similar offer. Patients residing in Massachusetts, Minnesota, and Rhode Island are eligible for assistance with medication costs, but are not eligible for assistance with infusion costs. Alexion reserves the right to rescind, revoke, or amend this program without notice. By participating in the Program, participants acknowledge that they understand and agree to comply with the complete terms and conditions, available at https://alexiononesource.com/copay.
Does Alexion OneSource pay for out of pocket?
The Alexion OneSource TM CoPay Program may help patients pay for eligible out-of-pocket medication and infusion costs.
Is Neisseria a serious infection?
Serious infections with Neisseria species (other than N. meningitidis ), including disseminated gonococcal infections, have been reported. Patients may have increased susceptibility to infections, especially with encapsulated bacteria.
Can Soliris cause anaphylaxis?
Administration of Soliris may result in infusion reactions, including anaphylaxis or other hypersensitivity reactions. Interrupt Soliris infusion and institute appropriate supportive measures if signs of cardiovascular instability or respiratory compromise occur.
How many patients were in the Soliris trial?
In the main clinical trial of Soliris, 61 patients in the Soliris treatment arm (98%) and 62 patients in the placebo arm (98%) were receiving 2 or more treatments prior to the start of the clinical trial.
How to contact MedWatch for Soliris?
Visit MedWatch, or call 1-800-FDA-1088. Please see the full Prescribing Information and Medication Guide for SOLIRIS, including Boxed WARNING regarding serious and life-threatening meningococcal infections. Enter.
How long do you have to carry a patient safety card?
Carry it with you at all times during treatment and for 3 months after your last SOLIRIS dose. It is important to show this card to any doctor or nurse to help them diagnose and treat you quickly.
How long should you take antibiotics before taking Soliris?
It is important that you have all recommended vaccinations before you start SOLIRIS, receive 2 weeks of antibiotics if you immediately start SOLIRIS, and stay up-to-date with all recommended vaccinations during treatment with SOLIRIS.
Can you pass out from a soliris infusion?
SOLIRIS can cause serious side effects including serious infusion-related reactions. Tell your doctor or nurse right away if you get any of these symptoms during your SOLIRIS infusion: chest pain; trouble breathing or shortness of breath; swelling of your face, tongue, or throat; and feel faint or pass out.
Can a soliris cause death?
SOLIRIS increases your chance of getting serious and life-threatening meningococcal infections that may quickly become life-threatening and cause death if not recognized and treated early.
Does Soliris lower the immune system?
SOLIRIS is a medicine that affects your immune system and can lower the ability of your immune system to fight infections.
Get REMS Certified to Prescribe SOLIRIS
Because of the risk of meningococcal infections, SOLIRIS is available only through a restricted program under a Risk Evaluation and Mitigation Strategy (REMS). Under the SOLIRIS REMS, prescribers must enroll in the program.
Call to Place an Order
Your Alexion customer operations representative can help streamline the ordering process.
Download our Coding & Billing Guide
SOLIRIS Coding and Billing Guide provides helpful information about patient access processes, coding, and billing for SOLIRIS to support reimbursement of claims related to the treatment of adult patients with anti-AChR antibody-positive gMG.
Claims Support
Please contact your field reimbursement manager or call Alexion OneSource™ for support with claims issues.
What Is Soliris?
Soliris (generic name: eculizumab) is a type of medication called monoclonal antibody, similar to antibodies that our bodies make to protect us when an unwanted substance enters our bodies.
How Is Soliris Used?
Atypical hemolytic-uremic syndrome (aHUS), which is a disease that mainly affects the kidney function. There is no specific age group for when this condition may occur.
Directions for Use
A calculated loading dose is given once weekly for a total of 4 weeks, then the calculated maintenance dose is administered at week 5 and then every 2 weeks thereafter.