What is the monthly cost of Zytiga?
The drug, abiraterone acetate marketed as ZYTIGA® now retails for more than $9,000 per month. Even patients with blue-ribbon health insurance can have co-pays ranging from $1,000 to $3,000 per month. Patients taking abiraterone acetate typically stay on the medication for 12 to 18 months.
Is Zytiga covered by insurance?
Yes. 100% of Medicare prescription drug plans cover this drug.
How long can you survive Zytiga?
Patients who received Zytiga had a median overall survival of 35.3 months compared with 30.1 months for those receiving the placebo.
How much does generic Zytiga cost?
The generic version of Zytiga is abiraterone acetate. The average retail price of Zytiga is around $12,781.54, but this cost can be reduced to $257.01 for 120, 250mg Tablet of generic Zytiga using a Zytiga coupon from SingleCare. These coupons are accepted at neighborhood pharmacies such as CVS, Walmart, and Walgreens.
Is there a generic version of ZYTIGA?
On November 23, 2018, Patriot Pharmaceuticals launched an authorized generic version of Janssen's Zytiga (abiraterone acetate) 250 mg tablets. — Apotex, Hikma, Mylan, and Teva also launched AB-rated generic versions of Zytiga 250 mg tablets.
What happens if you take ZYTIGA with food?
Do not take ZYTIGA® with food. Taking ZYTIGA® with food may cause more of the medicine to be absorbed by the body than is needed and this may cause side effects. Your healthcare provider may change your dose, if needed. Also, take your prednisone exactly how your healthcare provider tells you to.
How fast does Zytiga lower PSA?
The Zytiga started to work quickly. “Within two weeks, 100 percent of the pain was gone,” says Jeff. “Here we are, two months later; I haven't so much as taken an aspirin in six weeks. I had my PSA checked last week: it had dropped to .
What comes after Zytiga?
“Our data suggest that using a sequencing strategy of [Zytiga] followed by [Xtandi] provides the greatest clinical benefit,” they said.
What happens when hormone therapy stops working?
Most of the sexual and emotional side effects caused by low levels of androgens will eventually go away if a man stops taking hormone therapy. However, particularly for older men and those who received ADT for a long time, testosterone levels may not fully recover and these side effects may not disappear completely.
How much does ZYTIGA cost in Canada?
At the recommended dose, the average cost per 28-day course of abiraterone is $3,173. Based on economic analyses conducted by the manufacturer and by the pan-Canadian Oncology Drug Review, abiraterone was not considered cost-effective.
How often is ZYTIGA taken?
You take them once a day. Zytiga comes as a 250-mg tablet and a 500-mg tablet. The usual dosage is 1,000 mg once a day. You should take Zytiga without food (on an empty stomach).
Where can I buy ZYTIGA in USA?
Your Doctor's Office Pharmacy. If your doctor's office has its own pharmacy, your ZYTIGA® and prednisone may be available for pick-up there. However, it is more common to get ZYTIGA® through a specialty pharmacy. Your prednisone prescription may also be filled at any retail pharmacy.
How much does ZYTIGA cost in Canada?
At the recommended dose, the average cost per 28-day course of abiraterone is $3,173. Based on economic analyses conducted by the manufacturer and by the pan-Canadian Oncology Drug Review, abiraterone was not considered cost-effective.
How often do you take ZYTIGA?
You take them once a day. Zytiga comes as a 250-mg tablet and a 500-mg tablet. The usual dosage is 1,000 mg once a day. You should take Zytiga without food (on an empty stomach).
Where can I buy ZYTIGA in USA?
Your Doctor's Office Pharmacy. If your doctor's office has its own pharmacy, your ZYTIGA® and prednisone may be available for pick-up there. However, it is more common to get ZYTIGA® through a specialty pharmacy. Your prednisone prescription may also be filled at any retail pharmacy.
What is the difference between Yonsa and ZYTIGA?
Yonsa differs from Zytiga in several important Page 2 ways: (1) Zytiga has an additional FDA-approved indication of treatment of metastatic high-risk CSPC; (2) Yonsa is labeled to be used in combination with methylprednisolone, while Zytiga is labeled to be used in combination with prednisone; (3) Yonsa is a micronized ...
What is zytiga used for?
ZYTIGA ® is used to treat men with prostate cancer that has spread to other parts of the body.
What to do if you miss zytiga?
If you miss a dose of ZYTIGA ® or prednisone, take your prescribed dose the following day. If you miss more than 1 dose, tell your healthcare provider right away. Your healthcare provider will do blood tests to check for side effects.
What happens if you take Zytiga with prednisone?
Yellowing of the skin or eyes. Darkening of the urine. Severe nausea or vomiting. Increased risk of bone fracture and death when ZYTIGA ® and prednisone or prednisolone is used in combination with a type of radiation called radium Ra 223 dichloride.
How long after eating can you take zytiga?
Take ZYTIGA ® on an empty stomach, at least 1 hour before or at least 2 hours after a meal. Do not take ZYTIGA® with food.
How long after Zytiga can you breastfeed?
Males who have female partners who are able to become pregnant should use effective birth control (contraception) during treatment with ZYTIGA ® and for 3 weeks after the last dose of ZYTIGA ®. Are breastfeeding or plan to breastfeed. It is not known if ZYTIGA ® passes into your breast milk.
Can you take Zytiga with other medications?
ZYTIGA ® can interact with many other medicines. You should not start or stop any medicine before you talk with the healthcare provider that prescribed ZYTIGA ® . Know the medicines you take. Keep a list of them with you to show to your healthcare provider and pharmacist when you get a new medicine.
Can zytiga be taken with breast milk?
It is not known if ZYTIGA ® passes into your breast milk. Tell your healthcare provider about all the medicines you take or treatments you receive including prescription and over-the-counter medicines, vitamins, and herbal supplements. ZYTIGA ® can interact with many other medicines.
Is Zytiga safe for left ventricular ejection fraction?
The safety of ZYTIGA ® in patients with left ventricular ejection fraction <50% or New York Heart Association (NYHA) Class III or IV heart failure (in COU-AA-301) or NYHA Class II to IV heart failure (in COU-AA-302 and LATITUDE) has not been established because these patients were excluded from these randomized clinical trials [see Clinical Studies (14)] .
Does zytiga inhibit CYP3A4?
Drugs That Inhibit or Induce CYP3A4 Enzymes - Based on in vitro data, ZYTIGA ® is a substrate of CYP3A4. In a drug interaction trial, co-administration of rifampin, a strong CYP3A4 inducer, decreased exposure of abiraterone by 55%. Avoid concomitant strong CYP3A4 inducers during ZYTIGA ® treatment. If a strong CYP3A4 inducer must be co-administered, increase the ZYTIGA ® dosing frequency only during the co-administration period [see Dosage and Administration (2.3)]. In a dedicated drug interaction trial, co-administration of ketoconazole, a strong inhibitor of CYP3A4, had no clinically meaningful effect on the pharmacokinetics of abiraterone [see Clinical Pharmacology (12.3)] .
Is Zytiga safe for bilirubin?
The safety of ZYTIGA ® re-treatment of patients who develop AST or ALT greater than or equal to 20X ULN and/or bilirubin greater than or equal to 10X ULN is unknown.
Can you discontinue Zytiga?
Permanently discontinue ZYTIGA ® for patients who develop a concurrent elevation of ALT greater than 3X ULN and total bilirubin greater than 2X ULN in the absence of biliary obstruction or other causes responsible for the concurrent elevation.
Does Zytiga cause adrenocortical insufficiency?
Adrenocortical Insufficiency - Adrenocortical insufficiency was reported in patients receiving ZYTIGA ® in combination with prednisone, after an interruption of daily steroids and/or with concurrent infection or stress. Monitor patients for symptoms and signs of adrenocortical insu fficiency if prednisone is stopped or withdrawn, if the prednisone dose is reduced, or if the patient experiences unusual stress. Symptoms and signs of adrenocortical insufficiency may be masked by adverse reactions associated with mineralocorticoid excess seen in patients treated with ZYTIGA ®. Perform appropriate tests, if clinically indicated, to confirm adrenocortical insufficiency . Increased dosages of corticosteroids may be used before, during, and after stressful situations [see Warnings and Precautions (5.1)].
Does Zytiga cause hypokalemia?
Hypokalemia, Fluid Retention, and Cardiovascular Adverse Reactions Due to Mineralocorticoid Excess - ZYTIGA ® may cause hypertension, hypokalemia, and fluid retention as a consequence of increased mineralocorticoid levels resulting from CYP17 inhibition [see Clinical Pharmacology (12.1)]. Monitor patients for hypertension, hypokalemia, and fluid retention at least once a month. Control hypertension and correct hypokalemia before and during treatment.
Can zytiga cause fetal harm?
Females and Males of Reproductive Potential - ZYTIGA ® can cause fetal harm and potential loss of pregnancy. Advise males with female partners of reproductive potential to use effective contraception during treatment and for 3 weeks after the final dose of ZYTIGA ® [see Use in Specific Populations (8.1)].
What is zytiga used for?
ZYTIGA ® is used to treat men with prostate cancer that has spread to other parts of the body. It is not known if ZYTIGA ® is safe and effective in females or children. IMPORTANT SAFETY INFORMATION.
How to report side effects of zytiga?
THESE ARE NOT ALL THE POSSIBLE SIDE EFFECTS OF ZYTIGA®. Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Please see the full Prescribing Information and Patient Information for ZYTIGA ® and discuss any questions you have with your doctor.
What happens if you take Zytiga with prednisone?
Yellowing of the skin or eyes. Darkening of the urine. Severe nausea or vomiting. Increased risk of bone fracture and death when ZYTIGA ® and prednisone or prednisolone is used in combination with a type of radiation called radium Ra 223 dichloride.
How long after eating can you take zytiga?
Take ZYTIGA ® on an empty stomach, at least 1 hour before or at least 2 hours after a meal. Do not take ZYTIGA® with food.
How long after Zytiga can you breastfeed?
Males who have female partners who are able to become pregnant should use effective birth control (contraception) during treatment with ZYTIGA ® and for 3 weeks after the last dose of ZYTIGA ®. Are breastfeeding or plan to breastfeed. It is not known if ZYTIGA ® passes into your breast milk.
What to do if you miss zytiga?
If you miss a dose of ZYTIGA ® or prednisone, take your prescribed dose the following day. If you miss more than 1 dose, tell your healthcare provider right away. Your healthcare provider will do blood tests to check for side effects.
Can zytiga be taken with breast milk?
It is not known if ZYTIGA ® passes into your breast milk. Tell your healthcare provider about all the medicines you take or treatments you receive including prescription and over-the-counter medicines, vitamins, and herbal supplements. ZYTIGA ® can interact with many other medicines.
What is zytiga used for?
ZYTIGA ® is used to treat men with prostate cancer that has spread to other parts of the body.
How to report side effects of zytiga?
THESE ARE NOT ALL THE POSSIBLE SIDE EFFECTS OF ZYTIGA®. Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Please see the full Prescribing Information and Patient Information for ZYTIGA ® and discuss any questions you have with your doctor.
What happens if you take Zytiga with prednisone?
Yellowing of the skin or eyes. Darkening of the urine. Severe nausea or vomiting. Increased risk of bone fracture and death when ZYTIGA ® and prednisone or prednisolone is used in combination with a type of radiation called radium Ra 223 dichloride.
How long after eating can you take zytiga?
Take ZYTIGA ® on an empty stomach, at least 1 hour before or at least 2 hours after a meal. Do not take ZYTIGA® with food.
How long after Zytiga can you breastfeed?
Males who have female partners who are able to become pregnant should use effective birth control (contraception) during treatment with ZYTIGA ® and for 3 weeks after the last dose of ZYTIGA ®. Are breastfeeding or plan to breastfeed. It is not known if ZYTIGA ® passes into your breast milk.
What to do if you miss zytiga?
If you miss a dose of ZYTIGA ® or prednisone, take your prescribed dose the following day. If you miss more than 1 dose, tell your healthcare provider right away. Your healthcare provider will do blood tests to check for side effects.
Can you take Zytiga with other medications?
ZYTIGA ® can interact with many other medicines. You should not start or stop any medicine before you talk with the healthcare provider that prescribed ZYTIGA ® . Know the medicines you take. Keep a list of them with you to show to your healthcare provider and pharmacist when you get a new medicine.
What is zytiga used for?
ZYTIGA ® is used to treat men with prostate cancer that has spread to other parts of the body.
How to report side effects of zytiga?
THESE ARE NOT ALL THE POSSIBLE SIDE EFFECTS OF ZYTIGA®. Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Please see the full Prescribing Information and Patient Information for ZYTIGA ® and discuss any questions you have with your doctor.
What happens if you take Zytiga with prednisone?
Yellowing of the skin or eyes. Darkening of the urine. Severe nausea or vomiting. Increased risk of bone fracture and death when ZYTIGA ® and prednisone or prednisolone is used in combination with a type of radiation called radium Ra 223 dichloride.
How long after eating can you take zytiga?
Take ZYTIGA ® on an empty stomach, at least 1 hour before or at least 2 hours after a meal. Do not take ZYTIGA® with food.
How long after Zytiga can you breastfeed?
Males who have female partners who are able to become pregnant should use effective birth control (contraception) during treatment with ZYTIGA ® and for 3 weeks after the last dose of ZYTIGA ®. Are breastfeeding or plan to breastfeed. It is not known if ZYTIGA ® passes into your breast milk.
What to do if you miss zytiga?
If you miss a dose of ZYTIGA ® or prednisone, take your prescribed dose the following day. If you miss more than 1 dose, tell your healthcare provider right away. Your healthcare provider will do blood tests to check for side effects.
Can zytiga be taken with breast milk?
It is not known if ZYTIGA ® passes into your breast milk. Tell your healthcare provider about all the medicines you take or treatments you receive including prescription and over-the-counter medicines, vitamins, and herbal supplements. ZYTIGA ® can interact with many other medicines.
What is zytiga used for?
Zytiga (abiraterone) is a member of the miscellaneous antineoplastics drug class and is commonly used for Prostate Cancer.
Is zytiga a generic?
Prices are for cash paying customers only and are not valid with insurance plans. A generic version of Zytiga is available, see abiraterone prices. This Zytiga price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
What is zytiga used for?
ZYTIGA ® is used to treat men with prostate cancer that has spread to other parts of the body.
Can you have low blood sugar with zytiga?
Severe low blood sugar (hypoglycemia). Severe low blood sugar with ZYTIGA®can happen in people who have diabetes and take certain antidiabetic medicine s. You and/or your healthcare provider should check your blood sugar levels regularly during treatment with ZYTIGA®and after you stop treatment.
Can you change your Zytiga prednisone?
Do not change or stop taking your prescribed dose of ZYTIGA® or prednisone without talking to your healthcare provider first
Can you take Zytiga while pregnant?
Are pregnant or plan to become pregnant. ZYTIGA ® can cause harm to your unborn baby and loss of pregnancy (miscarriage). Females who are or may become pregnant should not handle ZYTIGA ® uncoated tablets or other ZYTIGA ® tablets if broken, crushed, or damaged without protection, such as gloves
Can you take prednisone with zytiga?
This can be life-threatening. To decrease the chance of this happening, you must take prednisone with ZYTIGA ® exactly as your healthcare provider tells you. Your healthcare provider will check your blood pressure, do blood tests to check your potassium levels, and check for any signs and symptoms of fluid retention every month during treatment with ZYTIGA ®
Can you take zytiga with food?
Do not take ZYTIGA® with food. Taking ZYTIGA ® with food may cause more of the medicine to be absorbed by the body than is needed, and this may cause side effects
Is zytiga safe for children?
ZYTIGA®is used to treat men with prostate cancer that has spread to other parts of the body. It is not known if ZYTIGA®is safe and effective in females or children. Important Safety Information For ZYTIGA®.
What is The Patient Assistance Program?
The Johnson & Johnson Patient Assistance Foundation, Inc. (JJPAF) is an independent, non-profit organization that is committed to helping eligible patients without insurance coverage receive prescription products donated by Johnson & Johnson operating companies.
Program Update
Patients may now choose the option of electronic income verification. Instead of submitting a copy of their Federal tax return, they can simply check a box on the updated application form.
Is Zytiga safe for left ventricular ejection fraction?
The safety of ZYTIGA ® in patients with left ventricular ejection fraction <50% or New York Heart Association (NYHA) Class III or IV heart failure (in COU-AA-301) or NYHA Class II to IV heart failure (in COU-AA-302 and LATITUDE) has not been established because these patients were excluded from these randomized clinical trials [see Clinical Studies (14)] .
Does zytiga inhibit CYP3A4?
Drugs That Inhibit or Induce CYP3A4 Enzymes - Based on in vitro data, ZYTIGA ® is a substrate of CYP3A4. In a drug interaction trial, co-administration of rifampin, a strong CYP3A4 inducer, decreased exposure of abiraterone by 55%. Avoid concomitant strong CYP3A4 inducers during ZYTIGA ® treatment. If a strong CYP3A4 inducer must be co-administered, increase the ZYTIGA ® dosing frequency only during the co-administration period [see Dosage and Administration (2.3)]. In a dedicated drug interaction trial, co-administration of ketoconazole, a strong inhibitor of CYP3A4, had no clinically meaningful effect on the pharmacokinetics of abiraterone [see Clinical Pharmacology (12.3)] .
Is Zytiga safe for bilirubin?
The safety of ZYTIGA ® re-treatment of patients who develop AST or ALT greater than or equal to 20X ULN and/or bilirubin greater than or equal to 10X ULN is unknown.
Can you discontinue Zytiga?
Permanently discontinue ZYTIGA ® for patients who develop a concurrent elevation of ALT greater than 3X ULN and total bilirubin greater than 2X ULN in the absence of biliary obstruction or other causes responsible for the concurrent elevation.
Does Zytiga cause adrenocortical insufficiency?
Adrenocortical Insufficiency - Adrenocortical insufficiency was reported in patients receiving ZYTIGA ® in combination with prednisone, after an interruption of daily steroids and/or with concurrent infection or stress. Monitor patients for symptoms and signs of adrenocortical insu fficiency if prednisone is stopped or withdrawn, if the prednisone dose is reduced, or if the patient experiences unusual stress. Symptoms and signs of adrenocortical insufficiency may be masked by adverse reactions associated with mineralocorticoid excess seen in patients treated with ZYTIGA ®. Perform appropriate tests, if clinically indicated, to confirm adrenocortical insufficiency . Increased dosages of corticosteroids may be used before, during, and after stressful situations [see Warnings and Precautions (5.1)].
Does Zytiga cause hypokalemia?
Hypokalemia, Fluid Retention, and Cardiovascular Adverse Reactions Due to Mineralocorticoid Excess - ZYTIGA ® may cause hypertension, hypokalemia, and fluid retention as a consequence of increased mineralocorticoid levels resulting from CYP17 inhibition [see Clinical Pharmacology (12.1)]. Monitor patients for hypertension, hypokalemia, and fluid retention at least once a month. Control hypertension and correct hypokalemia before and during treatment.
Can zytiga cause fetal harm?
Females and Males of Reproductive Potential - ZYTIGA ® can cause fetal harm and potential loss of pregnancy. Advise males with female partners of reproductive potential to use effective contraception during treatment and for 3 weeks after the final dose of ZYTIGA ® [see Use in Specific Populations (8.1)].
