Patient Assistance & Copay Programs for Symdeko Patient assistance programs (PAPs) are usually sponsored by pharmaceutical companies and provide free or discounted medicines and copay programs to low income or uninsured and under-insured people who meet specific guidelines. Eligibility requirements vary for each program.
Full Answer
What is Symdeko used to treat?
SYMDEKO is a prescription medicine used for the treatment of cystic fibrosis (CF) in patients age 6 years and older who have two copies of the F508del mutation, or who have at least one mutation in the CF gene that is responsive to treatment with SYMDEKO. Talk to your doctor to learn if you have an indicated CF gene mutation.
Are you eligible for Symdeko?
SYMDEKO is for the treatment of cystic fibrosis (CF) in patients age 6 years and older who have two copies of the F508del mutation, or who have at least one mutation in the CF gene that is responsive to treatment with SYMDEKO. Enter both of your mutations below to see if you're eligible for SYMDEKO.
How much does Symdeko cost at the pharmacy?
Symdeko Prices. This Symdeko price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies. The cost for Symdeko oral tablet (75 mg-50 mg and ivacaftor 75 mg) is around $23,395 for a supply of 56, depending on the pharmacy you visit.
Is Symdeko right for my child with CF?
Since CF is always working beneath the surface, your or your child’s treatment should be, too. SYMDEKO is tough on CF, because it targets the underlying cause in people 6 years and older with eligible mutations. CF is caused by cystic fibrosis transmembrane conductance regulator (CFTR) protein defects.
How to report Symdeko side effects?
What should I avoid while taking SYMDEKO?
About this website
How much does Symdeko cost per year?
Symdeko, as the drug is called, treats a similar population as Orkambi, but has been proven to be more effective. It carries a list price of $292,000 a year, and some analysts, including Geoffrey Porges, of Leerink, say they believe Symdeko will eventually replace Orkambi.
Is Symdeko better than Orkambi?
Symdeko seems to be more potent than Orkambi at dampening inflammatory responses. The study, “Different CFTR modulator combinations downregulate inflammation differently in cystic fibrosis,” was published in the journal eLife.
Is Trikafta better than Symdeko?
The panel voted 14-0 that the clinical evidence was adequate to demonstrate greater net health benefit for Trikafta compared with both best supportive care and Symdeko for patients homozygous for the F508del mutation.
Is Symdeko the same as Trikafta?
Trikafta is a combination of ivacaftor, tezacaftor and elexacaftor (previously coded as VX-445). Symdeko comprises ivacaftor and tezacaftor, while Orkambi is a combo of ivacaftor with lumacaftor.
What is the life expectancy for cystic fibrosis?
CF Foundation Patient Registry Based on 2019 Registry data, the life expectancy of people with CF who are born between 2015 and 2019 is predicted to be 46 years. Data also show that of the babies who are born in 2019, half are predicted to live to be 48 years or older.
What is the main cause of cystic fibrosis?
Cystic fibrosis is caused by a change (mutation) in the gene that makes cystic fibrosis transmembrane regulator (CFTR) protein. To have CF, a baby must get two copies of the CF gene, one from each parent.
Will Trikafta increase life expectancy?
Use of Trikafta could mean an increase in the life expectancy of cystic fibrosis patients, and for young children who begin the treatment early, “They might never have to experience the symptoms of cystic fibrosis in the same way prior to Trikafta,” Quinn said.
Does Trikafta cause weight gain?
Along with all the positive lung-related improvements, I also began to gain weight. My CF care team had said from the beginning that weight gain was experienced by people on Trikafta. I have been about the same weight within a few pounds for the past seven-to-eight years.
Is Trikafta covered by insurance in the US?
Do Medicare prescription drug plans cover Trikafta? Yes. 89% of Medicare prescription drug plans cover this drug.
How much does Trikafta improve lung function?
TRIKAFTA RESEARCH The findings show a significantly slower disease progression with an 18% increase in people with mild lung disease and 19% fewer hospitalizations or home intravenous antibiotics for pulmonary exacerbations.
Does Trikafta improve lung function?
Trikafta® works by improving the flow of chloride and water in patients who have a certain genetic defect and helps improve lung function and breathing.
Who is eligible for Trikafta?
Who is eligible to take Trikafta? The U.S. Food and Drug Administration (FDA) approved Trikafta for people with CF ages 6 years and older who have at least one copy of the F508del mutation or certain mutations in the CFTR gene that are responsive based on laboratory data.
Elexacaftor, Tezacaftor, and Ivacaftor - MedlinePlus
The combination of elexacaftor, tezacaftor, and ivacaftor is used to treat certain types of cystic fibrosis (an inborn disease that causes problems with breathing, digestion, and reproduction) in adults and children 6 years of age and older.
Kaftrio 75 mg 50 mg 100 mg film-coated tablets - medicines
Kaftrio 75 mg 50 mg 100 mg film-coated tablets - Summary of Product Characteristics (SmPC) by Vertex Pharmaceuticals (Europe) Limited
Elexacaftor/tezacaftor/ivacaftor - Wikipedia
Elexacaftor and Tezacaftor act as CFTR correctors to repair F508del processing by binding to the CFTR protein to increase the availability of CFTR protein on the cell surface. They work by modulating the position of the CFTR protein into the right position on the cell surface. The combination of increased CFTR protein in the correct position on the cell surface with ivacaftor's potentiation of ...
Drug Trials Snapshots: SYMDEKO | FDA
SYMDEKO is a drug for the treatment of cystic fibrosis (CF) in patients 12 years and older, who have specific gene mutations
What is Symdeko used for?
Symdeko (ivacaftor/tezacaftor) is a member of the CFTR combinations drug class and is commonly used for Cystic Fibrosis.
How much does a free drug card save?
The free Drugs.com Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions.
What is PAP in Boehringer Ingelheim?from boehringer-ingelheim.us
The PAP is one of the four core programs of Boehringer Ingelheim Cares Foundation.
What is a PAP?from boehringer-ingelheim.us
The PAP is one of the four core programs of Boehringer Ingelheim Cares Foundation. The other programs include the Product Donation Program, Financial Contributions Program, and Employee Volunteer Program. Through these programs, Boehringer Ingelheim provides more health in local U.S. communities and around the world. About Boehringer Ingelheim.
Does Boehringer Ingelheim Cares offer Medicare?from patientassistance.com
Boehringer Ingelheim CARES Foundation Patient Assistance Program For Medicare Beneficiaries, a patient assistance program provided by Boehringer Ingelheim Pharmaceuticals, Inc., offers the medications listed to the right at no cost to those who are eligible for the program. Eligibility is based off of the following requirements:
What to do after enrolling a patient?
After patient enrollment, you can notify the patient or caregiver that a Patient Support Specialist will be reaching out soon.
What can a patient support specialist send?
Your patient's Patient Support Specialist can send a summary of important information in the Enrolled Patient Report to help assess treatment adherence.
How to report Symdeko side effects?
These are not all the possible side effects of SYMDEKO. Call your doctor for medical advice about side effects. You are encouraged to report side effects to FDA at 1-800-FDA-1088. For further information, please see full Prescribing Information, including Patient Information.
What should I avoid while taking SYMDEKO?
SYMDEKO can cause dizziness in some people who take it. Do not drive a car, use machinery, or do anything that needs you to be alert until you know how SYMDEKO affects you
